Abstract: A low cost process for the high yield recovery of wheat gluten and starch is provided which comprises initially pearling whole wheat kernels to remove germ and a part of the bran, followed by grinding to an average particle size of 100-400 microns. The ground, pearled wheat is then subjected to wet processing to isolate gluten and starch. Yields of gluten are 20-25% higher than yields using flour as a starting material.
Type:
Grant
Filed:
March 28, 1991
Date of Patent:
November 17, 1992
Assignee:
Kansas State Univ. Research Foundation
Inventors:
Elieser S. Posner, Paul A. Seib, Qiang Zhuge
Abstract: An intracatheter pump apparatus and method is described for infusing fluids through a lumen of a catheter. The intracatheter pump includes a motor or power source on the outside of the catheter which causes movement of a fluid moving mechanism positioned in the lumen of the catheter, the fluid moving mechanism being attached to the distal end of an elongated member which in turn is attached to the motor.
Type:
Grant
Filed:
March 3, 1992
Date of Patent:
November 17, 1992
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: Novel thioimidazoles are 5-carboxyaldehyde-1-methyl-4-(phenylmethyl)thioimidazole and 5-(.alpha.-aminoacetyl)-1-methyl-4-(phenylmethyl)thioimidazole acid addition salt. The latter is prepared from the former by steps comprising Grignard addition to form 5-(1-hydroxyethyl)-1-methyl-4-(phenylmethyl)thioimidazole, oxidizing the hydroxy compound to form the corresponding ketone, brominating under acidic conditions to form the bromoacetyl derivative, converting the bromo in the bromoacetyl derivative to N,N-diformylamino and then hydrolyzing. The latter thioimidazole is an intermediate for forming 5-methylimidazo[4,5-e]-1,2-thiazin-4(5H)-one, that is neamphine, and for forming 3-chloro-(5-methylimidazo) [4,5-e]-1,2-thiazin-4(5H)-one, that is 3-chloroneamphine.
Abstract: An apparatus is disclosed to optically determine which of four fluorophores is attached to a band of DNA molecules on an electrophoresis gel. The apparatus includes four separate band pass interference filters and four wedge prisms to create four discrete areas of light on a detector. Digital comparison of the relative intensity of light sensed in the four discrete areas determines the identity of the excited fluorophore.
Abstract: Catalytic polymerization of dialkyl-, alkylaryl- or diaryldiethynylhydridosilanes cleanly affords soluble poly(silylene)vinylenes which can be shaped as fibers, films and bulk objects and thermally converted to silicon carbide.
Type:
Grant
Filed:
September 17, 1990
Date of Patent:
November 10, 1992
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: A soil desorption device and method which utilizes an easily manufacturable and assemblable pressure cell to contain soil samples. The pressure cells are in turn easily attachable to pneumatic pressure manifolds and can be independently valved. The cells are also easily adapted to be connected to collection containers for any desorbed fluid. Each cell utilizes a cylindrical container having rubber gaskets at opposite ends and which can be sandwiched between top and bottom plates to seal the container. A thin nylon membrane having small pores is positioned at the bottom of the container and the bottom plate has apertures to allow fluid forced through the membrane to pass to the fluid collection devices. This cell presents low impedance to fluid flow, produces high flow rates, and allows maintenance of good seals and accurate pressurization of each cell. These and other features and advantages allow for more economical and better soil desorption procedures and soil hydraulic characteristic measurements.
Type:
Grant
Filed:
October 16, 1990
Date of Patent:
November 10, 1992
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Mark D. Ankeny, Hugh J. Brown, Richard M. Cruse
Abstract: A selectively-sized, raw, low-rank coal is processed to produce a low ash and relative water-free agglomerate with an enhanced heating value and a hardness sufficient to produce a non-decrepitating, shippable fuel. The low-rank coal is treated, under high shear conditions, in the first stage to cause ash reduction and subsequent surface modification which is necessary to facilitate agglomerate formation. In the second stage the treated low-rank coal is contacted with bridging and binding oils under low shear conditions to produce agglomerates of selected size. The bridging and binding oils may be coal or petroleum derived. The process incorporates a thermal deoiling step whereby the bridging oil may be completely or partially recovered from the agglomerate; whereas, partial recovery of the bridging oil functions to leave as an agglomerate binder, the heavy constituents of the bridging oil. The recovered oil is suitable for recycling to the agglomeration step or can serve as a value-added product.
Type:
Grant
Filed:
July 12, 1991
Date of Patent:
November 10, 1992
Assignee:
University of North Dakota School of Engineering & Mines Foundation (UND-SEM Foundation)
Inventors:
Curtis L. Knudson, Ronald C. Timpe, Todd A. Potas, Raymond A. DeWall, Mark A. Musich
Abstract: A process for converting starch or partially hydrolyzed starch into a syrup containing dextrose includes the steps of saccharifying starch hydrolyzate in the presence of a saccharifying starch hydrolyzate in the presence of a mutated glucoamylase or related enzyme and increasing the selectivity of the enzyme for .alpha.-(1.fwdarw.4)-glucosidic bonds by the glucoamylase or related enzyme by including at least one mutation, the mutation substituting an amino acid of the enzyme with at least one amino acid chosen by comparison with structurally related regions of other enzymes that selectively hydrolyze only .alpha.-(1.fwdarw.4) glucosidic bonds.Enzymes made in accordance with the present invention are also disclosed.
Type:
Grant
Filed:
June 29, 1990
Date of Patent:
November 10, 1992
Assignee:
Iowa State University Research Foundation
Abstract: A tetrahydroquinoline alkaloid compound named "aspernomine" has been isolated from the sclerotia of the fungus Aspergillus nomius. Aspernomine has the structure: ##STR1## and is effective for controlling Lepidopteran insects.
Type:
Grant
Filed:
July 19, 1991
Date of Patent:
November 10, 1992
Assignees:
The United States of America as represented by the Secretary of Agriculture, University of Iowa Research Foundation, Biotechnology Research & Development Corporation
Inventors:
Gail M. Staub, Patrick F. Dowd, James B. Gloer, Donald T. Wicklow
Abstract: Insecticidal and acaricidal compounds of FormulaAR(CH.sub.2).sub.x O(CH.sub.2).sub.m A(CH.sub.2).sub.n (CE.sup.1 =CE.sup.2).sub.a (CE.sup.3 =CE.sup.4)CONR.sup.1 R.sup.2 (I)whereinAr is phenyl or naphthyl, in either case optionally substituted by one or more of optionally substituted C.sub.1-6 alkyl, optionally substituted C.sub.1-6 -alkylthio or C.sub.1-6 alkylthiooxy, halogen or optionally substituted C.sub.1-6 alkoxy,x=0 or 1m=1 to 7n=1 to 7A=CH.sub.2 or oxygena=0 or 1R.sup.1 and R.sup.2 are independently selected from hydrogen, C.sub.1-6 alkyl and C.sub.3-6 cycloalkyl (either of which may be substituted by one or more of halo, C.sub.1-6 alkyl, C.sub.2-6 alkenyl, CF.sub.2-6 alkoxy, C.sub.2-6 alkynyl, dioxalanyl and C.sub.3-6 cycloalkyl)E.sup.1, E.sup.2, E.sup.3 and E.sup.4 are independently selected from hydrogen, C.sub.1-4 alkyl, optionally substituted by halo, and nitrile, provided that at least one of E.sup.1, E.sup.2, E.sup.3 and E.sup.
Abstract: A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to degrade and release the macromolecular agent at a controlled rate. The method involves emulsifying a vinyl derivative of a biodegradable hydrophilic polymer, a water-soluble monovinyl monomer and a biologically active macromolecule in water, and copolymerizing the biodegradable hydrophilic polymer and the water-soluble monovinyl monomer such that the biologically active macromolecule is entrapped therein.
Type:
Grant
Filed:
January 9, 1990
Date of Patent:
November 3, 1992
Assignee:
The University of Kentucky Research Foundation
Abstract: An energy beam position detector including a shape memory alloy wire positioned at a boundary of acceptable beam trajectory. The wire is held under adjustable tension. A contraction detector monitors contraction of the wire. If the beam strays, is misaligned, or spreads and strikes the wire, the contraction detector can actuate a switch to alert personnel, shut off the beam, or can exert a force to enable other remedial action be taken.
Type:
Grant
Filed:
June 14, 1990
Date of Patent:
November 3, 1992
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: Multi-layer heterostructure transistors, and methods for making them, involve the use of a p+ doped GaAs gate for an n-channel device to increase barrier height and reduce turn-on threshold. A p++-i-p substrate helps to reduce source and drain capacitances and control short-channel effects. Use of one relatively high temperature photoresist in the fabrication process facilitates alignment of ohmic contact depositions with the source and drain regions.
Type:
Grant
Filed:
February 20, 1990
Date of Patent:
November 3, 1992
Assignee:
University of Virginia Alumni Patents Foundation
Abstract: Programs having multiple procedures are analyzed by creating a systThis invention was made with U.S. Government support awarded by the National Science Foundation (NSF), Grant #DCR-8603356 and PYI Award #DCR-8552602. The U.S. Government has certain rights in this invention.
Type:
Grant
Filed:
March 8, 1989
Date of Patent:
November 3, 1992
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Thomas Reps, Susan Horwitz, David Binkley
Abstract: A ponded infiltrometer including a bubble chamber formed in a base that supports a liquid reservoir. A single valve interposed in a channel between the bubble chamber and the reservoir controls both air flow into the device and water flow out of the device. A selectively movable bubble tube communicates between the bubble chamber and the atmosphere, and the position of the lower end of the bubble tube precisely regulates the amount of ponded water in the containment ring which contacts a section of soil. The base and attached reservoir are supported and secured above the containment ring by an adjustable tripod.
Type:
Grant
Filed:
April 10, 1991
Date of Patent:
October 27, 1992
Assignees:
Iowa State University Research Foundation, Inc., The United States of America as represented by the United States Department of Agriculture
Inventors:
Mark D. Ankeny, Tom Kaspar, Mark Prieksat
Abstract: A method is disclosed for stimulating the immune systems of animals with non-toxic lipid A derivatives. The derivatives include the lipopolysaccharide (LPS) and diphosphoryl lipid A (DPLA) for Rhodopsuedomonas.
Abstract: Sulfonic acid-substituted polyaniline salt compositions and uses therefor are disclosed. The sulfonated polyaniline salt compositions have fast electronic and optical responses to electrochemical potentials, improved environmental stability, and improved solubility. The sulfonated polyaniline salt compositions are useful as an ionic electrolyte polymer.
Type:
Grant
Filed:
May 25, 1990
Date of Patent:
October 27, 1992
Assignee:
Ohio State University Research Foundation
Abstract: Methods and systems are disclosed for encapsulating viable cells which produce biologically-active factors. The cells are encapsulated within a semipermeable, polymeric membrane by co-extruding an aqueous cell suspension and a polymeric solution through a common port to form a tubular extrudate having a polymeric outer coating which encapsulates the cell suspension. For example, the cell suspension and the polymeric solution can be extruded through a common extrusion port having at least two concentric bores, such that the cell suspension is extruded through the inner bore and the polymeric solution is extruded through the outer bore. The polymeric solution coagulates to form an outer coating. As the outer coating is formed, the ends of the tubular extrudate can be sealed to form a cell capsule. In one embodiment, the tubular extrudate is sealed at intervals to define separate cell compartments connected by polymeric links.