Abstract: An integrated circuit may include: a first transmission line; a second transmission line; a first compensator circuit suitable for generating a first compensation signal by delaying and differentiating a signal transferred through the second transmission line; a second compensator circuit suitable for generating a second compensation signal by delaying and differentiating a signal transferred through the first transmission line; a first receiver circuit suitable for receiving the signal transferred through the first transmission line, and compensating for the signal transferred through the first transmission line using the first compensation signal; and a second receiver circuit suitable for receiving the signal transferred through the second transmission line, and compensating for the signal transferred through the second transmission line using the second compensation signal.

Abstract: A system and method for reducing intrafractional motion of a subject The system includes a subject user device, whereby the user device includes an image acquisition device configured to receive location marker information of the subject to provide location marking data of the subject. The system may also include a digital processor configured to: receive the location marking data and determine movement of the subject relative to the location marker information; and communicate feedback of the movement to the subject to help the subject reduce intrafractional motion.

Abstract: The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.

Abstract: The present disclosure relates to antisense oligomers targeting the long non-coding RNA HOXB-AS3 and methods of treating acute myeloid leukemia.

Abstract: A capture device for capturing a biological substance can include: a substrate; a graphene-oxide layer on the substrate; at least one polydopamine polymer coupled with the graphene-oxide; and at least one targeting receptor coupled to the polydopamine(s), wherein the targeting receptor is capable of targeting/binding with a target biological substance. The graphene-oxide may be covalently coupled with the substrate and polydopamine, and the polydopamine may be covalently coupled with the targeting receptor. The targeting receptor can be an antibody or fragment thereof. The target biological substance can be an exosome. The substrate can be a particle (e.g., magnetic, such as magnetically responsive) or a surface in a microfluidic channel. The surface can be a top surface of a post, the post having a Y-shaped cross-sectional profile. In one aspect, the substrate is a particle. The capture device can include the target biological substance bound to the targeting receptor.

Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.

Abstract: An apparatus and methods for performing ablation of myocardial tissues are disclosed. The apparatus includes a plurality of ablation electrode configurations to which nanosecond pulsed electric fields are applied. The methods relate to therapies to treat cardiac arrhythmias, such as, atrial fibrillation and scar-related ventricular tachycardia, amongst others. The affected myocardial tissues are ablated creating a plurality of lesions enabled by the nanosecond pulsed electric fields applied to either penetrating electrodes, endo-endo electrodes, or endo-epi electrodes. Different electrophysiological tests are performed to assess the application of nanosecond pulsed electric field ablation to specific desired tissue location within the heart. Test results show the potential to overcome limitations of current ablation therapies, thereby providing patients and doctors a superior treatment for cardiac arrhythmias.

Abstract: A method, apparatus, and system to quantify tension forces of the anchor bolts for, e.g., SLTS support structures. A sensing assembly comprising one or more washers is installed along an anchor bolt. The sensing assembly comprises two spaced-apart surfaces between which a capacitance can be measured if electrical potential is created between the surfaces. The capacitance between the surfaces can be calibrated to bolt tension based on the relative distance between the surfaces. An RFRD circuit is connected to the two surfaces. An RF interrogation signal can supply the electrical potential and allow a reading of the responsive capacitance between surfaces to convert the capacitance reading into a bolt tension. Additionally, the introduction of the battery-free RFRD allows data to be acquired wirelessly from a distance, enabling an entirely new method of inspection. With minimum additional hardware cost, it provides a cost-effective way to replace traditional bolt installation and inspection methods.

Abstract: An antiaromatic compound and an organic light-emitting device including the same.

Abstract: A sample preparation device for electron microscopy (EM) that is configured to eliminate user-to-user variations and environment contaminations, which are often present in the conventional method of sample preparation. The device not only provides a means for evenly and reproducibly delivering a fluid or sample to an EM grid, but also provides a means for sealing the EM grid in an air-tight chamber and delivering air-sensitive samples to the EM grid. The platform may comprise readily fabricated glass chips with features integrated to preserve the integrity of the sample grid and to facilitate its extraction. The methods may eliminate the element of user dependent variability and thus improve the throughput, reproducibility and translation of these methods.

Abstract: The present invention demonstrates a technique for achieving milli-joule level and higher energy, broad bandwidth laser pulses centered around 2.4 micrometer with a kilohertz and other repetition rate. The key to such technique is to start with a broadband micro-joule level seed laser at around 2.4 micrometer, which could be generated through difference frequency generation, four-wave mixing process and other methods. This micro-joule level seed laser could then be amplified to above one milli-joule through chirped pulse amplification in a Cr2+:ZnSe or Cr2+:ZnS crystal pumped by a commercially available Ho:YAG or other appropriate suitable lasers. Due to the high seed energy, fewer gain passes are needed to achieve a milli-joule level output thus significantly simplifies laser architectures. Furthermore, gain narrowing effect in a typical chirped pulse amplifier is also mitigated and thus enable a broadband output.

Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.

Abstract: A method for managing health care patient record data including: associating, by a processor, native health care patient record data of a first patient stored in a database to a plurality of data fields, wherein the native health care patient record data of the first patient represents the first patient's health care record; assigning, by a processor, a relative importance weight score to each of the plurality of data fields; and generating, by a processor, a record strength score of the first patient's health care record based on the relative importance weight score assignments. The record strength score indicates a percentage of the first patient's health care record that contains important native health care patient record data.

Abstract: A power generation system burns a fuel in a gas in a combustion chamber, producing one or more combustion products and heating a working fluid, preferably supercritical CO2, that is chemically the same as a combustion product. The working fluid is mixed with the combustion products to form a combustion output mixture which is used in a turbine to drive a shaft of the turbine connected with a generator, producing electricity. The turbine outputs an exhaust that goes to a working fluid recycling system that connects the turbine outlet with the combustion chamber. The fluid recycling system has a radial compressor that receives and pressurizes the exhaust mixture and sends it to a chamber that has a bleed outlet and a recycling outlet.

Abstract: This document provides methods and materials for treating HIV infections. For example, methods and materials for using one or more proteosome inhibitors in combination with one or more other agents to treat HIV infections are provided.

Abstract: A skeletal fixation apparatus may include two or more bodies that are attached to two or more screws that have been inserted into vertebral bodies associated with a patient. The apparatus may also include two or more cylindrical members that are attached to the bodies to control the movement or alignment of the bodies when the skeletal fixation apparatus is being installed in the patient. The apparatus may further include a rod that includes a first curvature and a second curvature. The first curvature may be different than the second curvature and may be based on a medical diagnosis associated with stabilizing the vertebral bodies. The second curvature may enable the bodies to be immovably fastened to the rod in a manner that precludes the cylindrical members from contacting each other or causing a false torque condition to exist when the skeletal fixation apparatus is installed in the patient.

Abstract: This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wrist watch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.

Abstract: The functional effect of having additional color-sensing cone types in the human eye is implemented by an encoding of some spectral information differently for the left and right eyes. This different encoding for identical features seen by the left and right eyes is interpreted as a perceptively different feature by the human brain, allowing additional spectral information to be conveyed through the limited tristimulus sensitivity of the human eye.

Abstract: Methods and devices related to wound healing using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising Ring System 1, Ring System 2, Ring System 3, Ring System 4 or Ring System 5.

Abstract: A switching device, comprising an anti-ferromagnet structure having an upper layer and a lower layer, the upper layer and lower layer anti-ferromagnetically coupled by an exchange coupling layer, the upper and lower layer formed of a similar material but having differing volumes, and wherein the device is configured to inject symmetrically spin-polarized currents through the upper and lower layers to achieve magnetic switching of the anti-ferromagnet structure.