Abstract: An airway management device (10) for a human or animal subject (20) includes an airway tube (101) having a first end for disposal external to the subject (20) and a second end (102) for disposal in a portion of an airway of the subject (20). A light emitting element (108) and a photo-sensing element (109) may be disposed at the second end (102) of the airway tube (101). The light emitting element (108) may be configured to transmit light to tissue adjacent to the light emitting element (108). The photo-sensing element (109) may be configured to receive reflectance spectra (204) from the tissue. The location of the second end (102) of the airway tube (101) may be determined from characteristics of the reflectance spectra (204) of the tissue.

Abstract: A system for reconstruction of an explosion blast loading on a subject can include at least two pressure sensors and a computing system configured to: receive sensor data from the at least two pressure sensors, the sensor data being generated in response to an explosion blast wave; compute an explosion location and explosive charge mass of an explosive that caused the explosion blast wave based on the sensor data; and compute explosion blast loading on a subject from the explosion location and explosive charge mass. The pressure sensors can be configured as wearable pressure sensors or on equipment. The computing of the explosion location and explosive charge mass includes processing the sensor data through an inverse problem solver (IPS); and/or the computing of the explosion blast loading on the subject includes simulating the explosion blast wave with a forward problem solver (FPS).

Abstract: Described are a therapeutic monoclonal antibody specific for the Type Six Secretion System (T6SS) needle protein of Acinetobacter baumannii (A. baumannii) and methods of use. Specifically, the antibody specifically binds to hemolysin co-regulated protein (Hep). Further disclosed are methods of using an anti-Hep antibody for detecting A. baumannii in a sample as well as a mutant A. baumannii strain comprising a deletion or mutation in its genome such that said deletion or mutation interrupts the proper translation of its hep protein.

Abstract: A novel spacer assembly includes a body defining a bottom surface and a top surface opposite the bottom surface, a guide coupled to the top surface and extending along an axis, and a plurality of spacer elements movably coupled to the guide along the axis and being configured to receive a plurality of electrical leads therebetween. Each of the spacer elements extends above the top surface of the body and defines a predetermined width along the axis. When the leads are placed between the spacer elements, a spacing between adjacent ones of the leads corresponds to the predetermined width of the interposing spacer element. The predetermined width corresponds to a predefined electromagnetic compatibility (EMC) testing criteria. The spacer assembly facilitates rapid placement and accurate spacing of leads during initial EMC test setup or reconfiguration.

Abstract: The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines,

Abstract: Various embodiments associated with a heads-up display capable of functioning while underwater are described. An underwater mask can have a segment that a diver sees through and this segmented can be augmented with various portions that disclose information to the diver. These portions can relate to the diver herself or relate to other information such as the location of a source transmitting a signal. With these portions the diver can quickly learn about important information and act on that information.

Abstract: A system that can assess red blood cell AChE activity to provide warning of exposure and possibly inform treatment with medical countermeasures is disclosed. A portable, ideally hand-held, in vitro diagnostic point of care system capable of electrochemically-based detection of red blood cell acetylcholinesterase (AChE) activity from an undiluted whole blood sample provides a real-time pre-symptomatic warning of exposure to organophosphorus nerve agent or other poison, such as a pesticide, which informs treatment with medical countermeasures. One preferred version of the invention provides a system that uses highly stable test strips and a lightweight, low power hand-held potentiostat detector. The disclosed invention provides a real-time quantitative assessment of cholinesterase (ChE) enzymatic activity directly from a small whole blood sample for indication of exposure to ChE inhibiting substances (i.e.

Abstract: An apparatus for mounting surgical rails to a litter having a pair of parallel poles includes a surgical rail fixed to a clamp. The clamp is fixed to one of the parallel poles. A cross bar extends between the clamp and a second clamp fixed to the other of the parallel poles.

Abstract: Various embodiments are described that relate to failure determination for an integrated circuit. An integrated circuit can be tested to determine if the integrated circuit is functioning properly. The integrated circuit can be subjected to a specific radiation such that the integrated circuit produces a response. This response can be compared against an expected response to determine if the response matches the expected response. If the response does not match the expected response, then the integrated circuit fails the test. If the response matches the expected response, then the integrated circuit passes the test.

Abstract: Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I). A compound of Formula (I) can be administered prior to potential exposure of a species of Plasmodium, during potential exposure of a species of Plasmodium, and after potential exposure of a species of Plasmodium. The methods of the invention also pertains to kits comprising specific doses of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I), and instructions for administration of dosing quantity and frequency. The methods of the invention also pertain to determining doses of Formula (I) that meet the general regulatory requirement for a drug to be efficacious in the prevention of malaria in malaria-naïve subjects.

Abstract: A system or a method for assisting an individual to acclimatize to hot environment prior to being exposed to the hot environment using a measured heart rate with or without a measured skin temperature and/or a measured body core temperature. A Physiological Strain Index (PSI) or adaptive PSI (aPSI) is calculated for the individual to provide a target for the individual's exertion level such that an area under the calculated PSI/aPSI curve is used to determine the amount of heat acclimatization that has occurred for that particular training session and/or prior training sessions.

Abstract: The present invention addresses a need for antibodies useful for filovirus infections.

Abstract: Various embodiments are described that relate to patch antenna elements and parasitic feed pads. A patch antenna element can have a resistance and reactance. The resistance can be desirable while the reactance can be undesirable. To counteract the reactance, a parasitic feed pad can be placed near the patch antenna element and the parasitic feed pad produces a capacitance. The capacitance balances out the reactance to cancel out one another. When two patch antenna elements and two parasitic feed elements are employed in one antenna stack, the stack antenna can function as a dual band antenna.

Abstract: The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines.

Abstract: A guide system for use in electro-processing a bore of a gun barrel includes a non-conductive external bore guide and a non-conductive internal bore guide. The external bore guide is an adapter that is configured to removably engage the outside of the gun barrel and includes a conduit formed therein. The conduit is disposed such that it is axially aligned with a bore of the gun barrel when the external bore guide is engaged with the gun barrel. The internal bore guide is elongated and includes an axial recess that is sized to seat an electro-processing electrode (an anode). A method for uniformly plating the bore includes moving an anode through the gun barrel at one or more rate(s) of travel to uniformly plate the bore is also disclosed. The plating is sufficiently uniform to conform to military specifications. The systems, methods, support structures, etc. described herein are particularly well-suited to plating small-bore gun barrels.

Abstract: Various embodiments are described that relate to wave transmission from a vehicle, and reception of a response to the transmitted wave. A vehicle wheel can include a sensor that transmits a radio wave in front of the vehicle. The radio wave can reflect off a non-uniformity, such as a speed bump or pothole, and be returned to the sensor. A controller can compare the transmitted wave against the returned wave to identify the existence of the non-uniformity.

Abstract: Various embodiments that pertain to oxygen enrichment are described. Oxygen enrichment is shown to allow for independent control of both reformer residence time and the oxygen-to-carbon ratio during reforming. This allows for much better control over the reformer and for significant gains in reformer through-put without negative impacts to reformer performance. Additionally, the use of oxygen enriched reforming is shown to result in enhanced reformer performance, reduced degradation from catalyst poisons (carbon formation and sulfur) and enhanced fuel cell stack performance due to greatly increased hydrogen concentration in the reformate.

Abstract: Various embodiments are described that relate to energy generation. A housing can retain a spring coupled to a gear set. As the spring experiences linear compression and extension, the spring can cause rotational movement in the gear set. The rotational movement from the gear set can cause rotation of a rotational magnet. The rotational magnet, when rotated about a coil set, can convert an energy. The energy can be used to charge a battery.

Abstract: An embodiment of the invention provides a method including obtaining ultrasonic images of one or more vessel to be catheterized with an ultrasonic imaging device 212 and identifying the center(s) of the vessel(s) with the ultrasonic images. One of the vessels is punctured with a needle 220 based on the identifying of the center of the vessel. A guide wire 230 is inserted into the vessel and maneuvered with guide wire ultrasonic feedback control. The guide wire ultrasonic feedback control includes obtaining ultrasonic images of the vessel and the guide wire 230 in the vessel, and displaying the ultrasonic images of the vessel and the guide wire 230 in the vessel to a user. A catheter sheath 240 is inserted over the guide wire 230 and maneuvered with sheath ultrasonic feedback control. The guide wire 230 is removed and a catheter 250 is inserted into the catheter sheath 240 and maneuvered with catheter ultrasonic feedback control.

Abstract: Various embodiments are described that relate to an adaptive learning system. The adaptive learning system can be trained by correlation between a first set of raw technical performance data and a set of actual operational effectiveness assessment data. Once trained, the adaptive learning system can be deployed. Once deployed, the adaptive learning system can produce a set of predicted operational effectiveness assessment data from a second set of raw technical performance data that is different from the first set of raw technical performance data.