Patents Assigned to Governors of the University of Alberta
  • Patent number: 9744270
    Abstract: The invention provides compositions for the inhibition of bacterial adhesion. The composition can include nanocrystalline cellulose (NCC) and a water-soluble polymer, which form an NCC hydrogel in water. The NCC hydrogel can be used to treat or coat devices such as a catheter, whereby the NCC hydrogel inhibits bacterial adhesion to the catheter surface to thereby inhibit biofilm formation and growth of bacteria on the catheter surface. The compositions and devices can thus be useful for inhibiting or preventing conditions such as urinary tract infections.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: August 29, 2017
    Assignee: The Governors of the University of Alberta
    Inventors: Yaman Boluk, Yang Liu, Xiaohui Sun
  • Patent number: 9749388
    Abstract: Systems, methods, and devices for encoding and decoding data packets for transmission across a data network. To encode, data packets are first subjected to a an outer code process to result in outer coded packets. The outer coded packets are then divided into generations or groups of outer coded packets, each group or generation having an equal number of packets. Output packets are then created by forming random linear combinations of the outer coded packets from a specific generation or group of outer coded packets. The coefficients for the various elements of each linear combination is selected from a Galois field of values. To decode the incoming packets, enough packets are received until an iterative decoding process can be initiated.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: August 29, 2017
    Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Kaveh Mahdaviani, Raman Yazdani, Masoud Ardakani
  • Patent number: 9744245
    Abstract: There is provided a method of detecting in a sample the presence of an anti-M and/or anti-A and/or anti-C/Y antibody, the method comprising contacting the sample with a diagnostic conjugate provided according to the invention, comprising an oligosaccharide which comprises at least two units of 4,6-dideoxy-4-acylamido-?-pyranose and comprising at least one -(1-3)-link between adjacent 4,6-dideoxy-4-acylamido-?-pyranose units, in which the carbon at position 5 in the pyranose is linked to an R group, where R is independently selected from —CH2OH, —H or an alkyl group having at least one C atom, the oligosaccharide being covalently linked to a non-saccharide molecule or to a surface.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: August 29, 2017
    Assignees: THE SECRETARY OF STATE FOR ENVIRONMENT FOOD AND RURAL AFFAIRS, THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: John McGiven, David Bundle, Laurence Howells, Julie Guiard, Vijaya Ganesh Narayanaswamy
  • Patent number: 9718868
    Abstract: Described herein is insulin, an insulin-like growth factor, parathyroid hormone, a fragment of parathyroid hormone, or a parathyroid hormone related protein that includes at least one bone targeting moiety, wherein the bone targeting moiety is covalently bonded to the peptide. Also described herein are the methods of making these compositions that prevent or treat conditions associated with bone loss and preventing bone fractures, and/or the inability to initiate de novo bone turnover and stimulate bone fracture repair.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: August 1, 2017
    Assignee: The Governors of the University of Alberta
    Inventors: Michael Doschak, Yang Yang, Krishna Hari Bhandari
  • Publication number: 20170210641
    Abstract: Methods of using modified keratin to remove trace metals and/or napthenic acids from a waste water stream are described. The waste water stream may be mature or fine fluid tailings from oil sands operations, and the methods may include the removal of trace metals, naphthenic acids with simultaneous consolidation of the tailings. The keratin may be modified to unfold the keratin, disrupt disulphide bonding, add functional groups, and/or maintain or stabilize the unfolded configuration.
    Type: Application
    Filed: December 14, 2016
    Publication date: July 27, 2017
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Aman ULLAH, Tariq SIDDIQUE
  • Patent number: 9704101
    Abstract: A quantum device is provided that includes controllably quantum mechanically coupled dangling bonds extending from a surface of a semiconductor material. Each of the controllably quantum mechanically coupled dangling bonds has a separation of at least one atom of the semiconductor material. At least one electrode is provided for selectively modifying an electronic state of the controllably quantum mechanically coupled dangling bonds. By providing at least one additional electron within the controllably quantum mechanically coupled dangling bonds with the proviso that there exists at least one unoccupied dangling bond for each one additional electron present, the inventive device is operable at least to 293 degrees Kelvin and is largely immune to stray electrostatic perturbations. Room temperature operable quantum cellular automata and qubits are constructed therefrom.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: July 11, 2017
    Assignees: National Research Council of Canada, The Governors of the University of Alberta
    Inventors: Gino A. Dilabio, Robert A. Wolkow, Jason L. Pitters, Paul G. Piva
  • Publication number: 20170190844
    Abstract: A novel mussel-inspired injectable hydrogel with self-healing and anti-biofouling capabilities is developed, possessing great potential as drug delivery carrier. The hydrogel can heal autonomously from repeated structural damage and also effectively prevent nonspecific cell attachment and biofilm formation.
    Type: Application
    Filed: December 23, 2016
    Publication date: July 6, 2017
    Applicant: The Governors of the University of Alberta
    Inventors: Hongbo Zeng, Lin Li, Bin Yan
  • Publication number: 20170190749
    Abstract: Genetically encoded, photocleavable proteins are derived from a fluorescent protein. Upon illumination, the proteins photocleave and spontaneously dissociate into two or more fragments or release one end of an internal loop.
    Type: Application
    Filed: February 10, 2015
    Publication date: July 6, 2017
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Robert CAMPBELL, Wei ZHANG, Hiofan HOI
  • Patent number: 9694073
    Abstract: The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: July 4, 2017
    Assignees: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, ALBERTA HEALTH SERVICES
    Inventors: Michael Weinfeld, Dennis G. Hall, Feridoun Karimi-Busheri, Gary Kenneth Freschauf, Todd Randall Mereniuk
  • Patent number: 9694169
    Abstract: A gel assembly comprising a polymeric gel layer between metal layers. A gel assembly process comprising providing a colloidal polymer in solution, drying the solution to form a polymeric gel layer and forming metal layers on either side of the polymeric gel layer. A method of drug delivery comprising loading a polymeric gel layer with drug, forming metal layers on either side of the polymeric gel layer, wherein the polymeric gel layer comprises a material that is sensitive to a stimulus, and subjecting the polymeric gel layer to the stimulus to release the drug from between or through the metal layers.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: July 4, 2017
    Assignee: The Governors of the University of Alberta
    Inventor: Michael J. Serpe
  • Publication number: 20170174730
    Abstract: The invention, in some aspects relates to light-activated ion channel polypeptides and encoding nucleic acids and also relates in part to compositions comprising light-activated ion channel polypeptides and methods using light-activated ion channel polypeptides to alter cell activity and function.
    Type: Application
    Filed: March 1, 2017
    Publication date: June 22, 2017
    Applicants: Massachusetts Institute of Technology, The Governors of the University of Alberta, President and Fellows of Harvard College
    Inventors: Nathan Klapoetke, Edward Boyden, Yongku Cho, Brian Y. Chow, Gane K.S. Wong, Adam E. Cohen, Daniel R. Hochbaum
  • Publication number: 20170136442
    Abstract: A hydrogen sulphide adsorbent is formed from an alkali metal nanotitanate having a portion of the alkali metal cations exchanged with metal cations reactive with hydrogen sulphide, and heat treated. A method for producing the adsorbent includes the steps of mixing an alkali metal nanotitanate in powder form into an aqueous metal cation solution to produce a slurry, which is subsequently dehydrated to produce a powder, which is heat treated. A low temperature method for removing hydrogen sulphide from a gaseous mixture involves exposing the gaseous mixture to the aforementioned adsorbent, at a temperature less than 250° C. The adsorbent maintains a high adsorption capacity over a range of activation temperatures and humidity conditions.
    Type: Application
    Filed: August 27, 2014
    Publication date: May 18, 2017
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventor: Steven M. KUZNICKI
  • Patent number: 9624523
    Abstract: The present invention provides a simple culture device that is designed for manufacture and use in areas of limited resources. The device is useful for cell culture in such environments with limited resources because cells grow in paper just as they do in a culture dish. Also provided is a binding assay that employs an activatable dormant bacteriophage carrying a reporter gene to qualitatively or quantitatively detect the presence of a substance of interest in a sample.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: April 18, 2017
    Assignee: The Governors of the University of Alberta
    Inventors: Ratmir Derda, Maribel Elizabeth Funes Huacca, Simon Ng, Katrina Felicia Tjhung
  • Publication number: 20170088590
    Abstract: The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels.
    Type: Application
    Filed: November 23, 2016
    Publication date: March 30, 2017
    Applicants: Massachusetts Institute of Technology, The Governors of the University of Alberta
    Inventors: Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Gane Ka-Shu Wong, Yongku Peter Cho
  • Patent number: 9592497
    Abstract: The present disclosure provides a process for the mono-reduction of one or more imide moieties in a compound comprising contacting the compound with hydrogen gas and a catalyst comprising a transition metal hydride in the presence of a base, under conditions for the mono-reduction of the one or more imide moieties to form a compound comprising one or more hydroxy amides.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: March 14, 2017
    Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Steven H. Bergens, Satoshi Takebayashi
  • Publication number: 20170066973
    Abstract: A method of converting lipids to useful olefins includes reacting a mixture of lipids and a reactant olefin with microwave irradiation in the presence of ruthenium metathesis catalysts. The lipids may be unsaturated triacylglycerols or alkyl esters of fatty acids. The lipids may be sourced from renewable sources such as vegetable oil, waste cooking oil, or waste animal products.
    Type: Application
    Filed: September 6, 2016
    Publication date: March 9, 2017
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Aman ULLAH, Muhammad ARSHAD
  • Patent number: 9567502
    Abstract: The invention is directed to a method for preparing a polymer derived from an animal protein, such as in a feedstock derived from animal by-products. The method involves hydrolyzing proteins present in a feedstock to obtain hydrolyzed proteins, wherein hydrolysis is conducted under conditions sufficient to digest the proteins and destroy pathogens; extracting a protein fraction from the hydrolyzed proteins; and treating the protein fraction with a crosslinking reagent to form the polymer. The crosslinking reagents may include epoxies. The polymer may be further processed to form a thermoset plastic. The polymer may be used as an adhesive, or in the preparation of a natural fiber composite material.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: February 14, 2017
    Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: David Curtis Bressler, Phillip Choi
  • Patent number: 9535071
    Abstract: The present disclosure provides methods and compositions that find use in facilitating a diagnosis of inflammatory liver disease in a subject. The methods and compositions generally involve detection of eotaxin-3 (E3) levels, either alone or with levels of eotaxin-1 (E1), and optionally, with levels of CCL22 and, further optionally, with levels of IL15. These levels can be used to facilitate a diagnosis of a liver disease of at least one of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC), and/or to facilitate a differential diagnosis between AIH, PBC, and PSC. The methods and compositions of the present disclosure also find use in facilitating treatment decisions for a subject.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: January 3, 2017
    Assignees: The Governors of the University of Alberta, Medizinische Hochschule Hannover
    Inventors: Abdolamir Landi, Michael Houghton, D. Lorne Tyrrell, Tim Lankisch, Tobias Weismueller, Michael Manns
  • Patent number: 9529062
    Abstract: A liner for a bore of a waveguide is provided. The liner as an aperture passing through it and is formed of a metamaterial that has a relative electrical permittivity that is negative and near zero. When the liner is installed in the waveguide, it lowers the cutoff frequency of the waveguide while allowing the waveguide to remain hollow. This liner can be used in the bore of an MRI machine to lower the cutoff frequency of the bore of the MRI machine to allow the MRI machine to operate using waves having a lower frequency that if the liner was not used.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: December 27, 2016
    Assignees: The Governors of the University of Alberta, Alberta Health Services
    Inventors: Ashwin Iyer, Justin Pollock, Nicola de Zanche
  • Patent number: 9522515
    Abstract: The invention is directed to adhesives derived from animal or plant proteins, particularly canola and spent hen proteins. The adhesives are prepared by extracting the proteins by pH shifting; and either treating the extracted proteins with urea or sodium dodecyl sulfate, or polymerizing the proteins to form a protein-polymer conjugate. The invention is also directed to a wood based product comprising pieces of wood based material joined or consolidated with the adhesives.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: December 20, 2016
    Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Jianping Wu, Chanchan Wang