Patents Assigned to @HEALTH
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Publication number: 20250255497Abstract: Provided are method and device for non-invasive detection of central arterial pressure and other intraluminal large arterial pressures. Blood flow and vascular elasticity are the main factors affecting pulse waveform acquisition. A midstream airbag strap can be positioned at the same level as an intraluminal large artery in a human body, and an upstream signal channel can be positioned close to the trunk of the human body and thus is very close to the intraluminal large artery so that the influence of the vascular elasticity is minimized. On the basis of the relationship between the pressure in a blood vessel and the pressure of the airbag strap outside the blood vessel under the condition that the width of the midstream airbag strap is sufficient.Type: ApplicationFiled: April 13, 2022Publication date: August 14, 2025Applicant: SHENZHEN RAYCOME HEALTH TECHNOLOGY CO., LTD.Inventors: Xiaoguang WU, Zihuan WU
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Publication number: 20250255701Abstract: A compact liquid-outlet system comprising a liquid pump device, a liquid-inlet flow channel, and a liquid-outlet flow channel and an oral cleaning method. The liquid pump device comprises a liquid pump cavity, a piston slidably disposed in the liquid pump cavity, and a piston rod. The piston rod extends through the liquid pump cavity in a liquid-tight manner and is connected to the piston. The piston divides a pump chamber of the liquid pump cavity into a rod chamber and a rodless chamber. The piston comprises a liquid-outlet one-way valve allowing only liquid to flow from the rod chamber to the rodless chamber. The liquid-inlet flow channel communicates with the rod chamber through a liquid-inlet one-way valve. The liquid-outlet flow channel communicates with the rodless chamber. This system eliminates the need of extra space for installing the liquid-outlet one-way valve, resulting in a more compact structure.Type: ApplicationFiled: August 24, 2023Publication date: August 14, 2025Applicants: Bixdo (SH) Healthcare Technology Co.,Ltd., GuangDong Bixdo Health Technology Co.,Ltd.Inventor: Jiaquan FU
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Publication number: 20250255703Abstract: A throttling method for a dental irrigator, a throttling system, and a method for using the throttling system are provided. The throttling method comprises obtaining flow pulses showing a flow of the dental irrigator varying over time in a pulsatile manner during operation; defining a flow threshold, and dividing a region defined by a flow curve and a time axis within a single pulse cycle into high-flow spraying region and low-flow reflux regions; determining whether a present flow value of the dental irrigator is greater than the flow threshold; if yes, spraying out liquid in a liquid pump device of the dental irrigator through a nozzle; and if not, configuring the dental irrigator such that the liquid in the liquid pump device before and/or after a flow peak flows back to a liquid storage tank of the dental irrigator, making the cleaning liquid's impact on the oral cavity more rhythmic.Type: ApplicationFiled: August 24, 2023Publication date: August 14, 2025Applicants: Bixdo (SH) Healthcare Technology Co.,Ltd., GuangDong Bixdo Health Technology Co.,Ltd.Inventor: Jiaquan FU
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Publication number: 20250255495Abstract: Wearable sensor apparatus and methods. The wearable sensor apparatus includes a body temperature sensor to be placed in the xiphoid process of a user, a heart rate sensor to be placed in any curvilinear surface of the upper trunk of the chest; a microcontroller unit (MCU) contained within the wearable sensor apparatus and in operable connectivity with the at least one sensor device and configured to receive the gathered data and process it onboard the wearable sensor; and a communication module in operable connectivity with the MCU and configured to wirelessly transmit at least some of the gathered data to an external receiver.Type: ApplicationFiled: April 12, 2023Publication date: August 14, 2025Applicant: SIBEL HEALTH INC.Inventors: Ha Uk Chung, Daniel Lopez, Elena Kulikova, Husein Gonzalez
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Patent number: 12383596Abstract: A Chinese herbal medicine composition for boosting immunity, and a preparation method and use thereof are provided, belonging to the technical field of pharmaceutical preparations. The Chinese herbal medicine composition for boosting immunity is prepared with Lingnan authentic medicinal materials (Exocarpium Citri Grandis, dried tangerine peel, and Rhizoma Atractylodis) as a main drug, which is supplemented with affordable medicinal materials (Rosa roxburghii fruit, Fructus Lycii, Herba Cistanches, and saffron). The Chinese herbal medicine composition can be used in conjunction with moxibustion therapy to effectively improve the immunity of human body and relieve fatigue. Moreover, optimization of the preparation method can further improve a use effect of the drugs.Type: GrantFiled: November 14, 2024Date of Patent: August 12, 2025Assignees: Guangzhou University of Chinese Medicine, Zhongkefu Moxibustion (Hunan) Health Tech Co., Ltd.Inventors: Yunlong Bai, Yongchao Ning, Wei Zhang, Yan Yu
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Patent number: 12383609Abstract: The present invention provides a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, for example for use in a malaria vaccine. The present invention also provides nucleic acids encoding a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, compositions comprising a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1 and antibodies binding to a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1. The antibodies according to the present invention bind specifically to P. falciparum sporozoites and may be used in the treatment and/or prevention of malaria.Type: GrantFiled: April 19, 2018Date of Patent: August 12, 2025Assignees: Institute for Research in Biomedicine, Seattle Children's Hospital, Schweizerisches Tropen-und Public Health-InstitutInventors: Antonio Lanzavecchia, Joshua Hoong Yu Tan, Claudia Daubenberger, Brandon Wilder
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Patent number: 12383251Abstract: Various embodiments of a spinal shield having a shield body including a plurality of lateral extensions configured to be positioned over an exposed spinal canal for establishing a protective barrier around the contents of the exposed spinal canal are disclosed.Type: GrantFiled: February 15, 2024Date of Patent: August 12, 2025Assignee: Dignity HealthInventors: Michael A. Bohl, Randall Porter, Udaya Kumar Kakarla
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Patent number: 12385068Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.Type: GrantFiled: July 15, 2022Date of Patent: August 12, 2025Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
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Patent number: 12384834Abstract: Methods and compositions for preventing or treating cognitive decline associated with dementia and/or mild cognitive impairment and/or neurodegeneration using antibodies, peptides, fusion proteins, or genome editing systems that modulate HSPG/heparin binding affinities of ApoE.Type: GrantFiled: May 28, 2020Date of Patent: August 12, 2025Assignees: The General Hospital Corporation, Banner Health, The Schepens Eye Research Institute, Inc.Inventors: Yakeel T. Quiroz, Joseph F. Arboleda-Velasquez, Eric Reiman, Francisco Lopera
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Patent number: 12384820Abstract: The invention provides modified griffithsin polypeptides comprising the amino acid sequence of SEQ ID NO: 1, as well as corresponding nucleic acids, vectors, cells, fusion proteins, constructs, conjugates, and methods of inhibiting viral infection.Type: GrantFiled: April 19, 2022Date of Patent: August 12, 2025Assignees: University of Louisville Research Foundation, Inc., University of Pittsburgh—Of the Commonwealth System of Higher Education, The United States of America, As represented by the Secretary, Department of Health and Human ServicesInventors: Barry R. O'Keefe, Tinoush Moulaei, Kenneth E. Palmer, Lisa C. Rohan, Joshua L. Fuqua, Lindsay F. Kramzer
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Patent number: 12383618Abstract: Embodiments of a novel system for delivering an expression vector encoding an antigen to a subject that allows for spatiotemporal control over stimulation of the subject's immune response to the antigen are provided. In some embodiments, the expression vector delivery system includes a polymer linked to an adjuvant in prodrug form that can form polymer nanoparticles and enter a cell (such as an immune cell) under physiological conditions. In some embodiments, the adjuvant is linked to the polymer by an enzyme degradable labile bond, the cleavage of which activates the adjuvant to stimulate an immune response.Type: GrantFiled: October 6, 2020Date of Patent: August 12, 2025Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The Chancellor, Masters and Scholars of the University of OxfordInventors: Robert Seder, Geoffrey Lynn, Leonard Seymour
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Patent number: 12385872Abstract: A working wire for a biological sensor is disclosed. The working wire includes a substrate comprising cobalt-chromium (Co—Cr) alloy or Nitinol alloy, a platinum layer comprising platinum on the substrate, and a membrane layer comprising a biological membrane applied over the platinum layer.Type: GrantFiled: May 3, 2021Date of Patent: August 12, 2025Assignee: Allez Health Inc.Inventors: Robert James Boock, Khyati Mehta
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Patent number: 12386494Abstract: A system for dynamic user interface interactions comprising a computing device configured to receive behavior data, generate one or more educational modules and a selectable event graphic, configure a first remote device to display an event handler graphic corresponding to a data-reception event handler, receive from the first remote device a plurality of interactive data generated by at least the data-reception event handler, configure the first remote device to generate a graphical view, wherein the graphical view includes at least a display element generated as a function of the one or more educational modules and the selectable event graphic corresponding to a selectable event handler, wherein the selectable event handler is configured to receive interaction of the selectable event graphic and trigger an event action based on a comparison.Type: GrantFiled: November 23, 2024Date of Patent: August 12, 2025Assignee: Signet Health CorporationInventors: Blake Browder, Joy Figarsky
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Patent number: 12383401Abstract: A valve implant includes a valve leaflet prosthesis having a wire frame, a leaflet blade panel attached to the wire frame, and one or more tether struts extending from the wire frame, and a stent having a first end portion and a second end portion along a longitudinal stent axis, and a flexible extended stent strut extending longitudinally from the first end portion, wherein the one or more tether struts of the valve leaflet prosthesis is rotatably coupled to the flexible extended stent strut in a manner such that the one or more tether struts are rotatable about a rotational axis which is parallel to the one or more tether struts and which extends transverse to the longitudinal stent axis. A delivery system for the valve implant and a method of preparing the delivery system are also disclosed.Type: GrantFiled: August 22, 2019Date of Patent: August 12, 2025Assignees: SINGAPORE HEALTH SERVICES PTE LTDInventors: James R. Watson, Khung Keong Yeo
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Publication number: 20250249307Abstract: An exercise apparatus for leg exercises includes a frame, two first link rods, two second link rods, and two pedals. Each first link rod has a rotating portion and a first reciprocating portion respectively moving along a circular path and a first reciprocating path. Each second link rod has a second reciprocating portion moving along a second reciprocating path. Each first link rod has a first pivot portion connected to a second pivot portion of the corresponding second link rod. Each pedal is coupled to the corresponding second link rod, moving along an elongated closed path. The first reciprocating path, the second reciprocating path and the closed path are located below a lowermost position of the circular path, and height ranges of the first reciprocating path and the second reciprocating path at least partially overlap.Type: ApplicationFiled: January 9, 2025Publication date: August 7, 2025Applicant: Johnson Health Tech. Co., Ltd.Inventors: Meng-Hung Tsai, Joe Chen
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Publication number: 20250249457Abstract: Systems and methods for male fertility analysis may include: loading an aliquot of a male fertility sample into a chamber of an analysis system via an inlet, the chamber having an opening covered over by a porous membrane and a concave bottom opposite the opening; introducing media so that the membrane acts as a migration path for motile sperm; removing the media and a motile portion of the aliquot from the system into a container; sealing the container; and transporting the sealed container and a remainder of the male fertility sample to a testing facility. The testing facility may: determine a first concentration of the portion of the sample from the first container; determine a second concentration of the remainder; and estimate a percentage of total motile sperm for the sample based on the first concentration, the second concentration, and a predetermined relationship between portions and remainders of samples.Type: ApplicationFiled: October 21, 2024Publication date: August 7, 2025Applicant: Flow Health Services IncorporatedInventor: Sa XIAO
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Publication number: 20250248891Abstract: The present invention discloses a motor-driven rotating magnetic pole assisted standing health and leisure seat, comprising a sofa body and a sofa support connected thereto. The sofa body includes a seat cushion, a backrest, and a footrest. The backrest consists of a lumbar support and headrest from bottom to top, with both the lumbar support and seat cushion equipped with rotating magnetic motors to maximize the high-intensity, high-penetration magnetic field effect. By incorporating rotating magnetic motors in both the seat cushion and backrest, the invention achieves comprehensive coverage of most human body areas. The addition of six magnetic strips expands the magnetic field distribution range and coverage area. Through the combination of dynamic and static magnetic fields, users can better benefit from magnetic therapy, endowing the health and leisure seat with magnetic therapy effect and playing a role in health care.Type: ApplicationFiled: April 28, 2025Publication date: August 7, 2025Applicant: HEYE HEALTH TECHNOLOGY CO., LTDInventors: Shibiao ZHANG, Qunyong YAO, Yanwen FANG, Zhicai FANG
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Publication number: 20250249108Abstract: Embodiments include prodrug compounds, that can be used, inter alia, for treating an ailment such as cancer. The prodrug compounds can include an active agent component such as a cyclic monoterpene. The compounds can also include a prodrug component such as cholecalciferol or retinoic acid. Benefits of the prodrug compounds include increased solubility, increased half-lives, increased stability, increased lipophilicity, improved targeting (e.g., to tumor cells) and/or increased permeability/transmission across the blood-brain barrier.Type: ApplicationFiled: April 8, 2023Publication date: August 7, 2025Applicant: GATC Health CorpInventors: Ian Jenkins, Eric J. Mathur, Jonathan Lakey, Robert Tinder, Vaishnavi Narayan, Jayson Uffens
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Patent number: D1087791Type: GrantFiled: April 16, 2025Date of Patent: August 12, 2025Assignee: Anhui Huami Health Technology Co., Ltd.Inventors: Wei Po Chao, Wei Zheng
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Patent number: D1088150Type: GrantFiled: August 9, 2023Date of Patent: August 12, 2025Assignee: Vive Health LLCInventors: Juan Lopez, Joshua Reyes