Abstract: A balloon catheter having an elongated catheter shaft defining a fluid drainage lumen and a balloon inflation lumen. The balloon catheter includes a fluid drainage port disposed about the distal end of the catheter shaft in fluid communication with the fluid drainage lumen, and a balloon inflation port disposed about the distal end of the catheter shaft in fluid communication with the balloon inflation lumen. A balloon portion is disposed about the distal end of the catheter shaft in fluid communication with the balloon inflation port. A release device is disposed in fluid communication with the balloon portion and the fluid drainage lumen, and includes an activating member. A tether is attached to the activating member of the release device. Tension applied to the tether activates the release device, enabling fluid flow from the balloon portion into the fluid drainage lumen and out of the body.

Abstract: A method to reduce the likelihood of a dysbiosis of the vaginal microbiome in an individual employing a probiotic method and composition for maintaining a healthy vaginal microbiome, with particular embodiments including a bacterial formulation of at least two live bacteria selected from the group consisting of L. reuteri, L johnsonii and L. crispatus, and at least one prebiotic having glycogen as a component thereof. The bacterial formulation is administered to an individual's vagina in an amount sufficient for the bacterial formulation to generate an amount of tryptophan metabolites sufficient to act as aryl hydrocarbon receptor (AHR) agonists, thereby reducing inflammation in the individual's vagina. Certain embodiments include increasing the production of SCFAs in the individual's gut microbiome, while reducing the production of SCFAs in the individual's vagina and introducing ammonia oxidizing microorganisms to the individual's vagina.

Abstract: A method for detecting chromosomal abnormalities comprising conversion of a chromosomal image into an ideogram which is compared to a control or standard ideogram of a chromosome; or converting an ideogram of a chromosome into a chromosomal image.

Abstract: An exercise apparatus comprises a platform having a front roller, a rear roller and an endless belt mounted around the front roller and the rear roller for allowing a user to perform a first exercise type of a relatively lower resistance or a second exercise type of a relatively higher resistance. A front frame is mounted at a front side of the platform and has at least one holding portion adapted to be grasped by the user. One or more control interfaces controls the first exercise type and the second exercise type.

Abstract: This disclosure is directed to a method and system for matching human pose data in the form of 2D skeletons for the purposes of 3D reconstruction. The system may comprise a scoring module that assigns an affinity score to each pair of cross-view 2D skeletons, a matching module that assigns optimal pairwise matches based on the affinity scores, a grouping module that assigns each 2D skeleton to a group such that each group corresponds to a unique person, based on the pairwise matches; and a temporal consistency module that assigns each group an ID that maintains correspondence to the same person over the multi-video sequence.

Abstract: Vaccines are provided that elicit neutralizing antibodies to Epstein-Barr virus (EBV). Some vaccines comprise nanoparticles that display envelope proteins from EBV on their surface. The nanoparticles comprise fusion proteins comprising a monomeric subunit of a self-assembly protein, such as ferritin, joined to at least a portion of an EBV envelope protein. The fusion proteins self-assemble to form the envelope protein-displaying nanoparticles. Such vaccines can be used to vaccinate an individual against infection by different types of Epstein-Barr viruses as well as Epstein-Barr viruses that are antigenically divergent from the virus from which the EBV envelope protein was obtained. Also provided are fusion proteins and nucleic acid molecules encoding such proteins.

Abstract: Healthcare asset units are enabled to accomplish a healthcare facility management objective by first preparing the asset units in a pre-processing phase by using a computational processor to determine a first unique identifier for each asset unit. The prepared asset units are then transported in a removal phase to a manufacturer location, retrofit in a manufacturing phase at the manufacturer location by applying manufacturing processes to implement the durable information identifier on each asset unit, and by using a computational processor to determine a second unique identifier for each asset unit. The prepared asset units are then transported in a return phase, from the manufacturer location to a healthcare facility where the retrofitted asset units are subsequently used to accomplish a healthcare facility management objective.

Abstract: There is described herein a method of predicting recurrence free survival in a patient with meningioma comprising: (a) determining a tumor DNA methylation profile from a tumor sample from the patient, the tumor DNA methylation profile comprising the methylation status of at least 200 loci represented by the probes set forth in Table 9; and (b) calculating a risk of meningioma recurrence based on comparing the tumor DNA methylation profile and a reference methylation profile comprising the extent to which the methylation status of the at least 200 loci is associated with a risk of recurrence.

Abstract: A clinician station supporting private and secure telemedicine session between an operator and a patient on a remote patient station terminal. The clinician stations comprising a base, an interactive device stand, and a display terminal. The interactive device stand includes an electronic device, a device casing, and an adjustable arm. The display terminal includes a display device, a display casing, and an adjustable arm. The electronic device and the electronic display device are electronically communicable over a network with a cloud based system that is configured to host a medical session between a patient in the patient station terminal and the operator using the clinician station.

Abstract: The invention is directed to products and methods for preparing self-seeding vascular constructs generated as a bi-layered electrospun matrices, conjugated with EPC-specific antibodies and anti-thrombogenic agents on the inner surfaces of their lumens.

Abstract: Described herein are new synthetic routes for production of Endochin-Like Quinolone (ELQ) compounds. Synthetic routes to 3-substituted 4(1H)-quinolones are presented that are amenable to industrial scale preparation. One herein presented approach is relatively short, does not require palladium, and involves no chromatographic separation. A second herein presented approach is similarly relatively short, does not require palladium, involves no chromatographic separation, and also avoids high vacuum distillation. Additionally, both approaches require no protecting group chemistry because the insoluble 4(1H)-quinolone is not formed until the final reaction step.

Abstract: The present invention relates to a Gluconobacter thailandicus strain deposited under Accession No.

Abstract: The present invention relates to a carrier-formulated mRNA comprising at least one coding sequence encoding an influenza HA stem polypeptide, and to related aspects.

Abstract: An intelligent massage chair is provided. The chair includes a chair frame and armrests connected on left and right sides of the chair frame. At least one of the armrests is connected to the chair frame through a flipping device. The flipping device includes a base connected to the chair frame and a flipping fixed seat rotatably connected to the base around a rotation axis extending left and right, the flipping fixed seat is fixed to the at least one of the armrests. When the flipping device flips the armrest to a set position, the chair frame has a side entrance on the side of the armrest. The armrest can be rotated open from the side to form a side entrance for users to sit in the massage chair from the left and right sides, which is convenient for users to sit in the massage chair.

Abstract: A telemedicine platform utilizes artificial intelligence to match patients with practitioners. The platform includes a virtual assistant operable to automatically generate responses to a patient using machine learning in order to further identify details regarding the patient's symptoms and needs. The virtual assistant includes a digitally generated human face that automatically adapts mouth-movements and facial expressions to match the automatically generated responses in order to provide a feeling of interacting with a human assistant. The platform includes a patient interface, for identifying physicians and scheduling appointments, a practitioner interface, for managing patients and scheduling issues, and an administrator interface, for managing a larger practice of multiple practitioners.

Abstract: An interactive exercise apparatus for guiding a user to perform an exercise includes a frame, a mirror, a display device, a driving mechanism, and a control unit. The mirror is movably mounted on the frame and configured to reflect an image of the user. The display device is disposed on a backside of the mirror and visible through the mirror. The driving mechanism is configured to drive the mirror to move with respect to the frame. The control unit is operable to control the driving mechanism according to a location of the user so as to control the mirror to move to a suitable position where the user can see their reflected image.

Abstract: Compounds of Formula I and the pharmaceutically acceptable salts thereof are disclosed The variables X1, X2, and R1-4 are disclosed herein. The compounds are useful for treating cancer and related proliferative diseases. Pharmaceutical compositions containing compounds of Formula I and methods of treatment comprising administering compounds of Formula I are also disclosed.

Abstract: A probe including a first sensor having a first magnetometer and a first accelerometer and a second sensor having a second magnetometer and a second accelerometer is configured for determining the distance and direction to a marker. The marker may be magnetic and may be surgically inserted into a patient's body to mark a specific location. The probe may be used to locate the marker, thus identifying the location. The probe may include a microprocessor that receives an output from the first sensor and an output from the second sensor and determines the distance and direction to the marker.