Abstract: A magnetic field measurement system includes at least one magnetometer having a vapor cell, a light source to direct light through the vapor cell, and a detector to receive light directed through the vapor cell; at least one magnetic field generator disposed adjacent the vapor cell; and a feedback circuit coupled to the at least one magnetic field generator and the detector of the at least one magnetometer. The feedback circuit includes a first feedback loop that includes a first low pass filter with a first cutoff frequency and a second feedback loop that includes a second low pass filter with a second cutoff frequency. The first and second feedback loops are configured to compensate for magnetic field variations having a frequency lower than the first or second cutoff frequency, respectively.

Abstract: A method of making an array of vapor cells for an array of magnetometers includes providing a plurality of separate vapor cell elements, each vapor cell element including at least one vapor cell; arranging the vapor cell elements in an alignment jig to produce a selected arrangement of the vapor cells; attaching at least one alignment-maintaining film onto the vapor cell elements in the alignment jig; transferring the vapor cells elements and the at least one alignment-maintaining film from the alignment jig to a mold; injecting a bonding material into the mold and between the vapor cell elements to bond the vapor cell elements in the selected arrangement; removing the at least one alignment maintaining film from the vapor cell elements; and removing the bonded vapor cells elements in the selected arrangement from the mold to provide the array of vapor.

Abstract: An array of optically pumped magnetometers includes an array of vapor cells; and an array of beam splitters. The array of beam splitters is arranged into columns, including a first column, and rows. Each row and each column includes at least two of the beam splitters. The array of beam splitters is configured to receive light into the first column of the array and to distribute that light from the first column into each of the rows and to distribute the light from each of the rows into a plurality of individual light beams directed toward the vapor cells.

Abstract: An illustrative optical measurement device includes a light source configured to emit light pulses directed at a target. The optical measurement device further includes a detector configured to detect arrival times for photons of the light pulses after the photons are scattered by the target. The optical measurement device further includes a processing unit configured to generate, based on the arrival times of the photons at the detector, histogram data associated with the target. The processing unit is further configured to determine, based on the histogram data, an absolute optical property associated with the target. The processing unit is further configured to determine, based on the absolute optical property, a blood oxygenation level of the user, and perform an operation based on the blood oxygenation level.

Abstract: Source light having a range of optical wavelengths is generated. The source light is split into sample light and reference light. The sample light is delivered into a sample, such that the sample light is scattered by the sample, resulting in signal light that exits the sample. The signal light and the reference light are combined into an interference light pattern having optical modes, each having a direct current (DC) component and at least one alternating current (AC) component. Different subsets of the optical modes of the interference light pattern are respectively detected, and analog signals representative of the optical modes of the interference light pattern are output. Pair of the analog signals are subtracted from each other, and differential analog signals are output. The sample is analyzed based on the differential analog signals.

Abstract: An illustrative wearable brain interface system includes a headgear configured to be worn on a head of a user and a plurality of photodetector units configured to attach to the headgear, the photodetector units each housing a photodetector included in a plurality of photodetectors configured to be controlled by a master control unit to detect photons of light.

Abstract: A non-invasive self-autonomous system and method of optimizing a lifestyle regimen of a person containing a combination of lifestyle variables is provided. At least one value of the combination of lifestyle variables is repeatedly modified, thereby creating different variations of the combination of lifestyle variables respectively having different sets of values. The different variations of the combination of lifestyle variables are sequentially administered to the person. Physiological activity of the person is detected in response to the administration of the combination of lifestyle variables to the person. Sets of qualitative indicators of an aspect of a lifestyle of the person are derived from the detected physiological activity of the person. The lifestyle regimen of the person is optimized based on the different variations of the combination of lifestyle variables and the derived sets of qualitative indicators.

Abstract: A magnetic field recording system includes a headgear for a user; optically pumped magnetometers (OPMs) disposed in or on the headgear to detect magnetic fields and, in response to the detection, produce magnetic field data; at least one sensing modality including an optical sensing modality having at least one light source and at least one camera or light detector to receive light reflected or directed from the user and to produce an optical data stream; a tracking unit to receive the optical data stream and track a position or orientation of the headgear or user; a system controller to control operation of the OPMs and receive, from the tracking unit, the position or orientation of the headgear or user; and a processor to receive the optical data stream and the magnetic field data from the OPMs and analyze the magnetic field data using the optical data stream for validation.

Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity.

Abstract: A calibration arrangement of a magnetic field measurement device includes at least one attachment point nub configured for attachment to the magnetic field measurement device; mounting arms extending from the at least one attachment point nub; and reference coil loops distributed among the mounting arms. A magnetic field measurement system includes the calibration arrangement and a magnetic field measurement device including a sensor mounting body, magnetic field sensors disposed on or within the sensor mounting body, and at least one primary attachment point formed in or on the sensor mounting body configured to receive the at least one attachment point nub of the calibration arrangement.

Abstract: An illustrative wearable system includes a head-mountable component configured to be worn on a head of a user and a processor. The head-mountable component includes a time-to-digital converter (TDC) configured to receive, during a predetermined event detection time window that commences in response to an application of a light pulse to a target, a signal triggered by an event in which a photodetector detects a photon of the light pulse after the light pulse reflects from the target, the signal configured to enable a GRO of the TDC. The TDC is further configured to measure, using the GRO, a time interval between when the event occurred and an end of the predetermined event detection time window. The processor is configured to determine, based on the time interval and the predetermined event detection time window, an arrival time of the photon at the photodetector.

Abstract: A method for bonding together two substrates includes providing a molecular glue including glue molecules, each of the glue molecules having at least two —O—Si or —O—Al moieties; reacting a surface of a first substrate with the molecular glue to attach the glue molecules to the surface of the first substrate by at least one of the —O—Si or —O—Al moieties; and reacting a surface of a second substrate with the molecular glue to attach the glue molecules to the surface of the second substrate by at least another one of the —O—Si or —O—Al moieties. The method can be used for a variety of applications including manufacturing a vapor cell.

Abstract: An array of optically pumped magnetometers includes a vapor cell arrangement having a wafer defining one or more cavities and alkali metal atoms disposed in the cavities to provide an alkali metal vapor; an array of light sources, each of the light sources arranged to illuminate a different portion of the one or more cavities of the vapor cell arrangement with light; at least one mirror arranged to reflect the light from the array of light sources after the light passes through the one or more cavities of the vapor cell arrangement; and an array of detectors to receive light reflected by the at least one mirror, wherein each of the detectors is arranged to receive light originating from one of the light sources.

Abstract: A mental impairment detection system and non-invasive method of detecting mental impairment of a user are provided. A test (e.g., an inhibitory reflex test or a sustained attention test) is administered to the user, brain activity in a frontal lobe of the user is non-invasively detected while the test is administered to the user, and a level of mental impairment of the user is determined based on the brain activity detected in the frontal lobe of the user.

Abstract: An optical measurement system and method are provided. Pump sample light and probe sample light are delivered through into an anatomical structure of a user. The anatomical structure has molecules having a resonant vibrational frequency equal to the difference between a first optical frequency of the pump sample light and a second optical frequency of the probe sample light, whereby a portion of the probe sample light is inelastically scattered by the molecules as signal light encoded with a physiological event occurring in the molecules, and whereby sample light comprising the signal light exits the anatomical structure. Signal light in the exiting sample light is detected, and an electrical signal representative of the signal light is outputted. The electrical signal is analyzed, and based on this analysis, the presence and the depth of the physiological event in the anatomical structure is determined.

Abstract: A magnetometer includes a vapor cell having at least one wall, a chamber defined by the at least one wall, and alkali metal atoms disposed in the chamber to produce an alkali metal vapor in the chamber, wherein the at least one wall includes an oxide-containing interior surface; and an anti-relaxation coating disposed on the oxide-containing interior surface of the at least one wall of the vapor cell, wherein the anti-relaxation coating is a reaction product of the oxide-containing interior surface of the at least one wall with at least one mono- or dichlorosilane compound.

Abstract: A magnetic field measurement system that includes at least one magnetometer; at least one magnetic field generator; a processor coupled to the at least one magnetometer and the at least one magnetic field generator and configured to: measure an ambient background magnetic field using at least one of the at least one magnetometer in a first mode selected from a scalar mode or a vector mode; generate, in response to the measurement of the ambient background magnetic field, a compensation field using the at least one magnetic field generator; and measure a target magnetic field using at least one of the at least one magnetometer in a spin exchange relaxation free (SERF) mode which is different from the first mode.

Abstract: Disclosed herein are devices and methods for modifying a conventional imager to have functional features similar to that of a lock-in camera. Optical mask devices are configured to be coupled to conventional imager sensors and the configuration of the mask devices can be adjusted to acquire image data in rapid succession. One variation of an optical mask device comprises a substrate comprising a pattern of light-blocking and light-transmitting regions and an attachment structure for coupling the optical mask device to the imager. The substrate is configured to adjust the position of the light-blocking regions and light-transmitting regions relative to the light-sensing region of the imager based on a set of one or more predetermined substrate configurations. In some variations, the mask device and/or the imager sensor may be mechanically moved relative to each other based on the set of one or more predetermined substrate configurations.

Abstract: A magnetic field generator includes a first planar substrate, a second planar substrate positioned opposite to the first planar substrate and separated from the first planar substrate by a gap, a first wiring set on the first planar substrate, a second wiring set on the second planar substrate, and one or more interconnects between the first planar substrate and the second planar substrate. The one or more interconnects electrically connect the first wiring set with the second wiring set to form a continuous electrical path. The continuous electrical path forms a conductive winding configured to generate, when supplied with a drive current, a first component of a compensation magnetic field configured to actively shield a magnetic field sensing region located in the gap from ambient background magnetic fields along a first axis that is substantially parallel to the first planar substrate and the second planar substrate.

Abstract: A magnetic field measurement system for measurement of weak magnetic field signals or a wearable assembly includes at least one magnetometer and a shield disposed around the magnetometer. The shield includes a first portion configured for positioning between the at least one magnetometer and a source of the weak magnetic field signals. The first portion is made of an amplitude-selective magnetic shield (ASMS) that preferentially passes magnetic fields having a magnetic field amplitude below a threshold (for example, 500 nT or less) and shields magnetic fields having a larger magnetic field amplitude.