Patents Assigned to Hiroshima University
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Patent number: 9695235Abstract: The present invention provides a composition for regulating cell proliferation comprising a peptide having a partial amino acid sequence of BBF2H7 or an antibody capable of binding to the peptide. The problem has been solved by preparation of the peptide having a partial amino acid sequence of BBF2H7 which has a cell proliferation activity.Type: GrantFiled: August 28, 2013Date of Patent: July 4, 2017Assignee: Hiroshima UniversityInventors: Kazunori Imaizumi, Atsushi Saito
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Patent number: 9656351Abstract: Provided is a solder material that has a high melting point and exhibits superior mechanical characteristics, and therefore can form a connecting portion with high heat-resistant reliability.Type: GrantFiled: December 1, 2014Date of Patent: May 23, 2017Assignee: Hiroshima UniversityInventors: Kazuhiro Matsugi, Kenichiro Suetsugu
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Patent number: 9609872Abstract: Disclosed is an antibacterial agent composition which is highly safe and has excellent antibacterial abilities, by using a silicon-containing compound that is obtained by a specific manufacturing method. The antibacterial agent composition has a more stable antibacterial component, and is capable of imparting antibacterial abilities to teeth, while being also capable of cleaning an article or the mouth. Also disclosed are: an antiviral agent composition which is highly safe and has excellent virus deactivation abilities; an antibacterializing method, a cleaning/mouth rinsing method, each using the antibacterial agent composition or the antiviral agent composition; and a method for fixing an antibacterial agent or an antiviral agent. The antibacterial agent composition may contain a silicon-containing compound which is represented by general formula (1) and obtained by reacting a specific triethoxysilyl compound in an ethanol solvent.Type: GrantFiled: January 21, 2016Date of Patent: April 4, 2017Assignee: Hiroshima UniversityInventors: Hiroki Nikawa, Hironori Takeda, Toshio Kakihara, Takemasa Sakaguchi
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Patent number: 9605116Abstract: A method for secondary-molding a polymer nano oriented crystal material in accordance with an embodiment of the present invention includes the steps of: heating the polymer nano oriented crystal material so that the polymer nano oriented crystal material changes into a mobile phase or a melt having a dense entanglement network structure; molding the polymer nano oriented crystal material which changed into the mobile phase or the melt including the dense entanglement network in the step; and cooling the polymer nano oriented crystal material, which has undergone the step, until the polymer nano oriented crystal material changes into an ordered phase.Type: GrantFiled: October 7, 2011Date of Patent: March 28, 2017Assignees: SUNALLOMER LTD., HIROSHIMA UNIVERSITYInventors: Masamichi Hikosaka, Kiyoka Okada, Junichiro Washiyama, Takeshi Nakajima, Yuka Akiyama, Shingo Ueno
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Publication number: 20170073594Abstract: A gasification system includes a countercurrent type heat exchanger that includes a low-temperature side flow channel through which a gasification feedstock flows, and a high-temperature side flow channel to which treated water in a supercritical state is introduced. The treated water raises a temperature of the gasification feedstock by exchanging heat with the gasification feedstock. The system further includes a reactor that gasifies the gasification feedstock, whose temperature has been raised by the countercurrent type heat exchanger, by heating and pressurizing the gasification feedstock to be in a supercritical state. The reactor discharges the gasification feedstock as treated water in the supercritical state. The system further includes a treated water flow channel that introduces, to the countercurrent type heat exchanger, the treated water that has been discharged from the reactor, and a feedstock introduction port that introduces the feedstock to the low-temperature side flow channel.Type: ApplicationFiled: March 5, 2014Publication date: March 16, 2017Applicants: THE CHUGOKU ELECTRIC POWER CO., INC., HIROSHIMA UNIVERSITY, TOYO KOATSU CO., LTD.Inventors: Yasutaka Wada, Haruhito Kubota, Yukimasa Yamamura, Ichiro Uchiyama, Keiji Oyama, Toshiki Yamasaki, Yukihiko Matsumura, Yoshifumi Kawai, Takashi Noguchi
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Publication number: 20170073764Abstract: Disclosed is the provision of a method for assisting the detection of pancreatic cancer, the method assisting the detection of pancreatic cancer with high accuracy. In the method for assisting the detection of pancreatic cancer, the amounts of (1) miR-122-5p and (2) at least one miRNA selected from the group consisting of miR-16-5p, miR-19b-3p and miR-25-3p, all of which are contained in a test sample separated from a living body, are used as indicators. A larger amount of miR-122-5p and a smaller amount of at least one miRNA selected from the group consisting of miR-16-5p, miR-19b-3p and miR-25-3p than those in a healthy individual indicates that the living body is more likely to have developed pancreatic cancer.Type: ApplicationFiled: March 3, 2015Publication date: March 16, 2017Applicant: HIROSHIMA UNIVERSITYInventors: Hidetoshi TAHARA, Kozue IKEDA
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Publication number: 20170074592Abstract: A double tube and the like includes: a cylindrical outer tube; a cylindrical inner tube including a helical protrusion in an outer circumferential surface, the inner tube being provided inside the outer tube; and a helical flow passage forming member that forms a helical flow passage inside the inner tube, the helical flow passage forming member being provided inside the inner tube.Type: ApplicationFiled: March 5, 2014Publication date: March 16, 2017Applicants: THE CHUGOKU ELECTRIC POWER CO., INC., HIROSHIMA UNIVERSITY, TOYO KOATSU CO., LTD.Inventors: Yasutaka WADA, Haruhito KUBOTA, Yukimasa YAMAMURA, Ichiro UCHIYAMA, Keiji OYAMA, Toshiki YAMASAKI, Yukihiko MATSUMURA, Yoshifumi KAWAI, Takashi NOGUCHI
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Patent number: 9594069Abstract: In a vibration information detection step, a probe is inserted into a food sample, and any one of the displacement, the velocity or the acceleration of a vibration occurring on the probe by the insertion is detected as vibration information (step S1). In a frequency band dividing step, the vibration information is divided by a band pass filter into individual pieces of vibration information in each of a plurality of frequency bands (step S2). In a food texture index calculation step, a food texture index value based on vibrational energy per unit time in each of the frequency bands is calculated using a computer from the vibration information in each of the frequency bands and the center frequency of the corresponding frequency band (step S3).Type: GrantFiled: August 31, 2011Date of Patent: March 14, 2017Assignee: HIROSHIMA UNIVERSITYInventors: Naoki Sakurai, Shinichiro Iwatani, Hidemi Akimoto
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Publication number: 20170066981Abstract: A gasification apparatus heats and pressurizes a gasification feedstock to bring the gasification feedstock into a supercritical state, and performs decomposition-treatment on the gasification feedstock to obtain fuel gas. The gasification apparatus includes a heat exchanger, a gas-liquid separator, and a synthesizer. The heat exchanger introduces the gasification feedstock into a low-temperature-side flow channel and introduces treated fluid in a supercritical state into a high-temperature-side flow channel, so that heat exchange is performed between the gasification feedstock and the treated fluid. The gas-liquid separator extracts, from the high-temperature-side flow channel, the treated fluid that has been in a subcritical state due to heat exchange, performs gas-liquid separation on the treated fluid, and returns a separated liquid to the high-temperature-side flow channel. The synthesizer synthesizes a liquid fuel from fuel gas separated by the gas-liquid separator.Type: ApplicationFiled: March 5, 2014Publication date: March 9, 2017Applicants: THE CHUGOKU ELECTRIC POWER CO., INC., HIROSHIMA UNIVERSITY, TOYO KOATSU CO., LTD.Inventors: Yasutaka Wada, Haruhito Kubota, Yukimasa Yamamura, Ichiro Uchiyama, Keiji Oyama, Toshiki Yamasaki, Yukihiko Matsumura, Yoshifumi Kawai, Takashi Noguchi
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Publication number: 20170066982Abstract: A gasification apparatus heats and pressurizes a gasification feedstock to bring the gasification feedstock into a supercritical state, and performs decomposition-treatment on the gasification feedstock to obtain fuel gas. The gasification apparatus includes a heat exchanger, a gas-liquid separator, and a turbine. The heat exchanger introduces the gasification feedstock into a low-temperature-side flow channel and introduces treated fluid in a supercritical state into a high-temperature-side flow channel, so that heat exchange is performed between the gasification feedstock and the treated fluid. The gas-liquid separator extracts, from the high-temperature-side flow channel, the treated fluid that has been in a subcritical state due to heat exchange, performs gas-liquid separation on the treated fluid, and returns a separated liquid to the high-temperature-side flow channel. The turbine is powered by fuel gas separated by the gas-liquid separator.Type: ApplicationFiled: March 5, 2014Publication date: March 9, 2017Applicants: THE CHUGOKU ELECTRIC POWER CO., INC., HIROSHIMA UNIVERSITY, TOYO KOATSU CO., LTD.Inventors: Yasutaka Wada, Haruhito Kubota, Yukimasa Yamamura, Ichiro Uchiyama, Keiji Oyama, Toshiki Yamasaki, Yukihiko Matsumura, Yoshifumi Kawai, Takashi Noguchi
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Publication number: 20170067691Abstract: A heat exchanger includes: a flow passage unit arranged with a plurality of planar flow passage bodies each arranged with two flow passages adjacent to each other in a same plane. The plurality of the planar flow passage bodies are layered in an intersecting direction that intersects with the plane. In two of the planar flow passage bodies adjacent in the intersecting direction of the plurality of the layered planar flow passage bodies, each one of two flow passage ports in both ends of each of the flow passages of one of the planar flow passage bodies is connected to each one of two flow passage ports in both ends of each of the flow passages of another of the planar flow passage bodies. A high-pressure pipe covers an outside of the flow passage unit.Type: ApplicationFiled: March 5, 2014Publication date: March 9, 2017Applicants: THE CHUGOKU ELECTRIC POWER CO., INC., HIROSHIMA UNIVERSITY, TOYO KOATSU CO., LTD.Inventors: Yasutaka Wada, Haruhito Kubota, Yukimasa Yamamura, Ichiro Uchiyama, Keiji Oyama, Toshiki Yamasaki, Yukihiko Matsumura, Yoshifumi Kawai, Takashi Noguchi
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Publication number: 20170044597Abstract: An object of the present invention is to provide a method of detecting a nucleic acid binding protein and a method of screening for a binding inhibitor or promoter for a nucleic acid binding protein. According to the present invention, there is provided a method of detecting binding between a nucleic acid and a nucleic acid binding protein, comprising determining the degree of structural change in a nucleic acid complex having at least two nucleic acid duplex moieties.Type: ApplicationFiled: August 23, 2016Publication date: February 16, 2017Applicant: Hiroshima UniversityInventors: Hidetoshi TAHARA, Toru MIYAGI
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Patent number: 9526523Abstract: A fixation device set S includes an external fixation device which is attached on one end-side of first and second pins; and a pin fixture which is attached on the other end-side. The external fixation device includes a first and a second permanent magnets disposed with their same poles opposed to each other; a first holding portion provided in the first permanent magnet; a second holding portion provided in the second permanent magnet; first limiter portions sandwiching the first and the second permanent magnets from a second direction; and second limiter portions connecting the first limiter portions to each other. The first pins are inserted through through-holes in the first holding portion, whereas the second holding portion is attached to the second pin via a ball joint.Type: GrantFiled: June 11, 2013Date of Patent: December 27, 2016Assignees: HITACHI METALS, LTD., HIROSHIMA UNIVERSITYInventors: Masaaki Aoki, Mitsuo Ochi
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Publication number: 20160364503Abstract: An industrial product design system includes: a muscle activity acquisitor that acquires muscle activity required for each action of a given body area when a product user moves the body area to use an industrial product to be designed; a muscle activity normalizer that normalizes the acquired muscle activity; a function operator that calculates, as a design value change rate, mapping of the normalized muscle activity using a given function; and a design value corrector that corrects the design value of the industrial product to be designed with the design value change rate.Type: ApplicationFiled: August 24, 2016Publication date: December 15, 2016Applicant: HIROSHIMA UNIVERSITYInventors: Yuichi KURITA, Toshio TSUJI, Masaya KONDO, Yusuke KISHISHITA
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Publication number: 20160363598Abstract: Provided are a sweat allergy antigen, an antibody capable of binding to the antigen specifically, and others, which are produced utilizing a microorganism-originated protein that exists in sweat allergy patient in a dissolved state or a partial peptide of the protein.Type: ApplicationFiled: August 26, 2016Publication date: December 15, 2016Applicant: Hiroshima UniversityInventors: Michihiro Hide, Takaaki Hiragun, Kaori Ishii, Shoji Mihara, Makiko Hiragun, Jens-M Schroeder
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Publication number: 20160354868Abstract: Provided is a solder material that has a high melting point and exhibits superior mechanical characteristics, and therefore can form a connecting portion with high heat-resistant reliability.Type: ApplicationFiled: December 1, 2014Publication date: December 8, 2016Applicant: HIROSHIMA UNIVERSITYInventors: Kazuhiro Matsugi, Kenichiro Suetsugu
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Publication number: 20160350912Abstract: An endoscopic image diagnosis support system (100) includes: a memory (10) that stores learning images pre-classified into pathological types; and a processor (20) that, given an endoscopic image, performs feature value matching between an image of an identification target region in the endoscopic image and the learning images, to identify the pathological types in the identification target region.Type: ApplicationFiled: February 2, 2015Publication date: December 1, 2016Applicant: HIROSHIMA UNIVERSITYInventors: Tetsushi KOIDE, HoangAnh TUAN, Shigeto YOSHIDA, Tsubasa MISHIMA, Satoshi SHIGEMI, Toru TAMAKI, Tsubasa HIRAKAWA, Rie MIYAKI, Kouki SUGI
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Patent number: 9499822Abstract: A simple and inexpensive method for selectively culturing a microorganism which method makes it possible to selectively culture a microorganism of interest even without using a sterilization operation or an antibiotic substance is provided. The method according to the present invention selectively culturing a microorganism includes the step of culturing, in a culture medium containing phosphorous acid as a sole phosphorous source, a recombinant microorganism into which a phosphite dehydrogenase gene has been introduced.Type: GrantFiled: August 8, 2013Date of Patent: November 22, 2016Assignee: HIROSHIMA UNIVERSITYInventors: Akio Kuroda, Ryuichi Hirota, Takenori Ishida
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Publication number: 20160326246Abstract: The present invention provides a composition for regulating cell proliferation comprising a peptide having a partial amino acid sequence of BBF2H7 or an antibody capable of binding to the peptide. The problem has been solved by preparation of the peptide having a partial amino acid sequence of BBF2H7 which has a cell proliferation activity.Type: ApplicationFiled: July 28, 2016Publication date: November 10, 2016Applicant: Hiroshima UniversityInventors: Kazunori Imaizumi, Atsushi Saito
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Patent number: 9457071Abstract: Provided are a sweat allergy antigen, an antibody capable of binding to the antigen specifically, and others, which are produced utilizing a microorganism-originated protein that exists in sweat allergy patient in a dissolved state or a partial peptide of the protein.Type: GrantFiled: June 25, 2013Date of Patent: October 4, 2016Assignee: Hiroshima UniversityInventors: Michihiro Hide, Takaaki Hiragun, Kaori Ishii, Shoji Mihara, Makiko Hiragun, Jens-M Schroeder