Abstract: The present subject matter is directed to a luminogen exhibiting aggregation induced emission, wherein T1, T2, and T3 comprise one or more polyynes as a conjugated bridge. The present subject matter is also directed to an AIEgen comprising a hydrophilic pyridium group as a strong electron-withdrawing group; a piperazine group as an electron-donating group; and a ?-Cyanostilbene; wherein the AIEgen exhibits aggregation induced emission. The present subject matter is directed to a method of synthesizing an AIEgen and is further directed to a method of labeling comprising incubating a subject having cells with a conjugate formed by conjugating an AIEgen with an antibody; and selectively labeling desired cells by turn-on imaging, wherein labeling occurs when the desired cells are selectively stained by fluorescent emission of the AIEgen upon degradation of the antibody after cellular internalization of the conjugate through endocytosis.
Type:
Grant
Filed:
July 21, 2017
Date of Patent:
February 14, 2023
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
Benzhong Tang, Xiujuan Shi, Yee Yung Yu, Tsz Kin Kwok, Zheng Zhao, Pengfei Zhang, Huifang Su
Abstract: Provided herein are small molecular acceptor compounds containing thiophene end groups, methods for their preparation and intermediates used therein, the use of formulations containing the same as semiconductors in organic electronic devices, especially in organic photovoltaic and organic field-effect transistor devices, and to organic electronic and organic photovoltaic devices made from these formulations.
Type:
Grant
Filed:
April 30, 2020
Date of Patent:
December 27, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: Embodiments disclosed herein represent powder based additive manufacturing processes which provide a microstructure having improved mechanical properties. The methods may include the use of ultrasonic excitation in combination with the active control of a substrate's temperature to provide some level of control over the microstructure and hence the properties.
Type:
Grant
Filed:
December 9, 2016
Date of Patent:
December 27, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
George Alexandru Tilita, Wenhao Chen, Chi Fong Kwan, Matthew Ming Fai Yuen
Abstract: An architecture is provided for cooperative target tracking and signal propagation learning using mobile sensors. A method can comprise as a function of sensing data representative of a location of a target device at a first defined moment and model data relating to a motion model representing a probability density function, determining, by a system comprising a processor, a group of locations for the target device at a second defined time point, wherein the probability density function facilitates determining, based on the location of the target device at the first defined moment, a current location of the target device at a third defined moment; and as a function of the group of locations, generating, by the system, a data structure representing a matrix of received signal strength values; and identifying, by the system, a location of the group of locations for the target device at the third defined moment based on the data structure.
Type:
Grant
Filed:
August 26, 2019
Date of Patent:
December 13, 2022
Assignee:
The Hong Kong University of Science And Technology
Abstract: The moisture-resistant catalyst for air pollution remediation is a catalyst with moisture-resistant properties, and which is used for removing nitrogen compound pollutants, such as ammonia (NH3), from air. The moisture-resistant catalyst for air pollution remediation includes at least one metal oxide catalyst, at least one inorganic oxide support for supporting the at least one metal oxide catalyst, and a porous framework for immobilizing the at least one metal oxide catalyst and the at least one inorganic oxide support, where the porous framework is moisture-resistant. As non-limiting examples, the at least one metal oxide catalyst may be supported on the at least one inorganic oxide support by precipitation, impregnation, dry milling, ion-exchange or combinations thereof. The at least one metal oxide catalyst supported on the at least one inorganic oxide support may be physically embedded in the porous framework.
Type:
Grant
Filed:
March 20, 2020
Date of Patent:
November 29, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: Various embodiments disclosed herein enable a mobile device to accurately locate where the mobile device is located indoors by measuring geomagnetic fields, and tracing relative changes in the magnetic fields as the mobile device is moved. The relative changes can be compared to a fingerprint signal map, and a trace of a portion of the path can be determined by matching the relative changes in the magnetic fields to relative changes in the fingerprint signal map. A collection of the path portions can then be connected by determining a shortest path that connects each of the path portions. In another embodiment, a step counter can also be used to constrain possible locations, and fuse the geomagnetic field and step counter information for joint indoor localization.
Type:
Grant
Filed:
February 5, 2018
Date of Patent:
November 15, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: Aspects describe a nanotube array gas sensor, and methods to manufacture and use the same. In one example, the nanotube array gas sensor comprises an insulator template including an array of parallel aligned, open-ended nanotubes; a sensing material deposited on at least interior surfaces of the nanotubes; and catalyst nanoparticles distributed on the sensing material. An electronic controller activates electrodes made of different conductor materials in order to obtain multiple measurements of electrical resistance across the insulator template. The electrical resistance measurements can be compared to electrical resistance profiles in order to determine types and concentrations of gases in the nanotube array gas sensor.
Type:
Grant
Filed:
April 29, 2019
Date of Patent:
October 11, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: A device (1) comprises: a cylindrical shell (4); a first spring (5) encased inside the cylindrical shell (4); a second spring (6) encased inside the cylindrical shell (4); a separator (13) in the cylindrical shell (4) separating the first and second springs (5, 6); a first end plate (12) on a first side (13a) of the separator (13) and a second end plate (11) on a second side (13b) of the separator (13); a first rod (2) and a second rod (3) passing openings (20a, 20b) provided at each end of the cylindrical shell (4), with the first rod (2) connected to the first end plate (12) and the second rod (3) connected to the second end plate (11); and a spacer (14) inserted between the first end plate (12) and the first spring (5).
Type:
Grant
Filed:
January 4, 2017
Date of Patent:
September 20, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
Charles Wang Wai Ng, Clarence Edward Choi, Dongri Song
Abstract: A resistive random-access memory (ReRAM) includes a hybrid memory cell. The hybrid memory cell includes: (a) a left resistance-switching device comprising a first terminal and a second terminal, (b) a right resistance-switching device comprising a first terminal and a second terminal, wherein the first terminal of the right resistance-switching device is connected to the first terminal of the left-resistive switching device at an internal node, and (c) a transistor comprising a source terminal, a drain terminal, and a gate terminal, wherein the drain terminal of the transistor is connected to the left resistance-switching device and the right resistance-switching device at the internal node.
Type:
Grant
Filed:
July 11, 2018
Date of Patent:
September 13, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
Kwang Ting Cheng, Miguel Angel Lastras MontaƱo
Abstract: A nanoparticle film is disclosed. The nanoparticle film comprises a plurality of polymerized liquid crystal monomers having an axis of alignment, and a plurality of nanoparticles disposed in the polymerized liquid crystal monomers. Each of the nanoparticles has a surface modified by a plurality of first ligands and a long axis aligned with the axis of alignment through the plurality of first ligands.
Type:
Grant
Filed:
August 7, 2020
Date of Patent:
September 13, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: Modeling, constructing, and designing conformal cellular structures with spatially variable and graded microstructures that have full geometric continuity is disclosed, which includes defining a global structural domain, where the microstructures are generated for a global mesh, defining a unit structure as a base cell using a level set function, which allows for beams, trusses, shells, and solids, transforming and mapping the base cell into each element of the global mesh using an isoparametric transformation, which creates a conformal cellular structure in accordance with a set of requirements on distribution of material and/or mechanical properties, and applying a global cutting function to guarantee geometric continuity in connections on the common face of any two neighboring cells of the structure. As a result, more complex geometric shapes and features can be generated at the cell level, while maintaining the specified geometric connectivity across the cells of the structure.
Type:
Grant
Filed:
August 10, 2018
Date of Patent:
August 30, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: Disclosed are a method of manufacturing a polyethylene membrane comprising: stretching a polyethylene film in a first direction during a first stretching; attaching a plurality of rods on side edges of the polyethylene film; attaching a tape on the polyethylene film; stretching the polyethylene film having the rods attached thereto in a second direction during a second stretching; and annealing the polyethylene film after the second stretching. The second direction can be a transverse direction of the first direction, and the first stretching and the second stretching can be performed at the same (or higher) temperature and the same stretching speed as each other.
Type:
Grant
Filed:
December 18, 2018
Date of Patent:
July 19, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: A theranostic agent can be used in both photoacoustic imaging (PAI) and photothermal therapy (PTT) applications. The theranostic agent can include a small molecule, organic compound with absorption in the near-infrared (NIR) interrogation window (700-900 nm). The compound can be a biocompatible organic nanoparticle (ONP). The theranostic agent can be effectively used in PAI and PAI-guided PTT applications. The theranostic agent can be administered to a patient to locate a tumor site in the patient using in vivo imaging techniques. Once the tumor site has been determined, the tumor site can be irradiated with near-infrared light to stop or inhibit the growth of the tumor.
Type:
Grant
Filed:
May 14, 2018
Date of Patent:
July 19, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: Microfluidic devices to efficiently remove particulate matter (PM) in air are provided, as are methods of fabricating and using the same. A device can include a channel having a structure configured to generate chaotic advective flow in air within the channel. The channel structure can include a plurality of SHMs disposed within the channel, where each SHM comprises a plurality of grooves each having a width of 200 ?m or less and a spacing between each groove of 200 ?m or less. The plurality of SHMs can be configured to introduce microvortices in air flow within the channel.
Type:
Grant
Filed:
May 2, 2019
Date of Patent:
July 5, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: AIE-active chemosensors, according to the present teachings, exhibit UV-vis absorption change and become non-luminescent upon protonation. Upon deprotonation, the chemosensors revert to their original absorption and emission. This deprotonation process can be triggered in the presence of amines, and specifically, biogenic amines. The chemosensors can detect amine species, e.g., biogenic amines produced during food fermentation, quickly and with high sensitivity. Further, due to the AIE nature of the compounds, the chemosensors can be loaded onto a physical support and sealed inside a food package to monitor food spoilage.
Type:
Grant
Filed:
May 16, 2018
Date of Patent:
May 17, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
Benzhong Tang, Parvej Alam, Nelson Lik Ching Leung
Abstract: The present subject matter relates to a fluorescent compound having aggregation-induced emission (AIE) characteristics. The compound can undergo spontaneous hierarchical self-assembly from a vesicle to a helical fiber in the aggregate state. A composition capable of providing circularly polarized luminescence can include the fluorescent compound and at least one additional compound selected from the group consisting of an aggregation-caused quenching luminogen and an aggregation-induced emission luminogen.
Type:
Grant
Filed:
October 2, 2019
Date of Patent:
May 17, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: The present subject matter relates to compounds that have aggregation-induced emission (AIE) characteristics and are capable of generating Raman signals in the Raman cell-silent region (1800 cm?1-2800 cm?1). The compounds can be used in dual-mode cell imaging by fluorescence and Raman microscopes.
Type:
Grant
Filed:
April 18, 2018
Date of Patent:
May 3, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: A method for stretching a plurality of sample isolates, including: trapping the plurality of sample isolates away from a wall of at least one microfluidic channel of a microfluidic flow system; generating a microfluidic flow to stretch the plurality of trapped sample isolates; determining deformation characteristics of the plurality of stretched samples isolates based on one or more frames from an image processing system; and outputting information corresponding to the deformation characteristics.
Type:
Grant
Filed:
January 13, 2020
Date of Patent:
May 3, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
Zhanshi Yao, Ching Chi Kwan, Andrew Wing-On Poon
Abstract: Methods of synthesizing few-layer two-dimensional (2D) Sb2S3 nanosheets using scalable chemical exfoliation are provided. The 2D Sb2S3 nanosheets can be developed as bi-functional anode materials in both lithium ion batteries and sodium ion batteries. The unique structural and functional features brought by 2D Sb2S3 nanosheets can offer short electron/ion diffusion paths and abundant active sites for surface redox reactions.
Type:
Grant
Filed:
July 26, 2019
Date of Patent:
April 12, 2022
Assignee:
The Hong Kong University of Science and Technology
Abstract: A composite photoalignment layer for aligning liquid crystal molecules includes: a monomeric material; a photoinitiator or a thermal initiator; and an azo dye material. A method for preparing a composite photoalignment layer for aligning liquid crystal molecules includes: mixing, in solution form, a monomeric material, a photoinitiator or a thermal initiator, and an azo dye material; coating the mixed solution onto a substrate to form a thin film; exposing the thin film to polarized light; and, with a thermal initiator, heating the thin film to polymerize the monomeric material and form a solid thin film.
Type:
Grant
Filed:
September 22, 2020
Date of Patent:
April 5, 2022
Assignee:
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Inventors:
Man Chun Tseng, Abhishek Kumar Srivastava, Cuiling Meng, Vladimir Grigorievich Chigrinov, Hoi Sing Kwok, Yue Shi, Yeuk Lung Jacob Ho, Chenxiang Zhao