Abstract: A method and system for reporting medical data including both current and past medical results for medical tests performed on a patient is provided. The medical data is output in columns, and the current results and past results of the same medical test are presented in the same row. In this manner, the report is provided in a layout that has rows and columns, so that all current results are presented in one column, and all past results are presented in a separate column. In addition, graphs of the medical results can be displayed to illustrate current and past medical results in a view that allows for trend and comparative diagnosis.

Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.

Abstract: Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

Abstract: Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

Abstract: A fluid pressure control device, including a pressurized fluid inlet, a first valve in fluid communication with the pressurized fluid inlet and controlling the flow of fluid from the pressurized fluid inlet, a first pressure measurement device detecting a fluid pressure downstream of the first valve, and a controller electrically coupled to the first valve. The first pressure measurement device causes the controller to operate the first valve such that a fluid downstream of the first valve is maintained at a substantially constant pressure.

Abstract: Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (—SH) group or hydroxyl (—OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.

Abstract: A method for determining the amount of NT-proBNP in blood samples from felines. The method includes detecting degradation products of feline NT-proBNP by various methods, including using antibodies, kits and devices.

Abstract: Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.

Abstract: The invention provides methods and compositions for the detection of Ehrlichia chaffeensis.

Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.

Abstract: An optical system includes a laser diode, a collimating lens and first and second housing parts. The first housing part retains the collimating lens therein. The second housing part engages the first housing part to retain the laser diode therebetween. The position of the laser diode is adjustable with respect to the collimating lens in X, Y and Z directions. One or more biasing members are interdisposed between the housing parts in the X direction, the Y direction, and/or the Z direction for biasing the laser diode relative to the collimating lens in the X direction, the Y direction and/or the Z direction. One or more securing members fixedly engage the first and second housing to one another and provide a compression force on the housing parts to maintain the relative position of the laser diode with respect to the collimating lens in the X, Y and Z directions.

Abstract: Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of whipworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, roundworm, and heartworm. Confirmation of the presence or absence of whipworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

Abstract: The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of a pharmaceutically active agent and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions. One particular type of condition for which the pharmaceutical compositions are useful is a microbial infection, e.g., of the skin, ear, or eye, especially for veterinary applications.

Abstract: An automated method for calibrating in real time a diagnostic analyzer includes the steps of receiving diagnostic results of patient samples calculated by the analyzer using pre-set parameters of the analyzer, and calculating the centroid of the analyzer's diagnostic results. The centroid of the analyzer's diagnostic results is subtracted from a centroid of diagnostic results of a field population of comparable analyzers to obtain a bias in the centroid of the analyzer's diagnostic results. The bias is compared to predetermined limits Should the bias fall outside the predetermined limits, an optimization factor is derived and applied to the analyzer's diagnostic results to obtain optimized results from the analyzer without changing the pre-set parameters of the analyzer.

Abstract: A method of normalizing an analyzer response value of a fluorescence analyzer is provided. The method includes measuring an excitation spectrum of the analyzer and measuring an emission sensitivity spectrum of the analyzer. Next, a normalization factor based at least in part upon the excitation spectrum of the analyzer and the emission sensitivity spectrum of the analyzer is determined. The sample is then analyzed to obtain an uncorrected analyzer response value. A normalized analyzer response value is calculated based at least in part upon the uncorrected analyzer response value and the normalization factor.

Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.

Abstract: The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal by injection. When the pharmaceutical compositions are administered to an animal by injection, they form a drug depot that releases the pharmaceutically active compound over time. The pharmaceutical compositions can also be administered orally.

Abstract: The present disclosure describes a method of monitoring disease progression in a mammal positive for immunodeficiency virus which includes collecting blood cells from a mammal to obtain a first blood sample adding antibodies such as CD4 and CD8 to the first blood sample scanning the blood sample to produce a first multivariate dot plot which may be used to quantify at least CD4+ and CD8+ blood cell populations to produce a first ratio. The first multivariate dot plot may also be used to quantify a CD8??low subpopulation which may be used to calculate a second ratio. A third ratio is calculated of the second ratio to the first ratio and the result plotted on a graph as a first point. This process may be repeated to produce a second point for evaluating an extent of disease progression.

Abstract: A slide cartridge for use with a chemical analyzer includes an upper ring and a lower ring secured together but rotatable with respect to each other. The upper and lower rings define a plurality of reaction chambers between them, which receive dry analyte test slides. A gear track formed in the underside of the lower ring engages a pinion gear attached to a stepping motor of the chemical analyzer in order to rotate the slide cartridge. The slide cartridge is rotated under a sample fluid metering device, which deposits a sample fluid on the test slides through a plurality of spotter ports formed in the upper ring, and above a reflectometer, which performs a colorimetric measurement on the spotted test slides through viewing windows formed in the lower ring of the slide cartridge. A chemical analyzer with which the slide cartridge may be used includes a reflectometer, a sample fluid metering device and a stepping motor for rotating the slide cartridge.