Patents Assigned to IDEXX Laboratories
  • Pharmaceutical compositions for the administration of aptamers
    Patent number: 8114440
    Abstract: Pharmaceutical compositions comprising an aptamer and an amino acid ester or amide or an aptamer; a divalent metal cation; and a carboxylic acid, a phospholipid, a phosphatidyl choline, or a sphingomyelin. Methods of treating or preventing a condition in an animal comprising administering to the animal the pharmaceutical compositions.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: February 14, 2012
    Assignee: Idexx Laboratories Inc.
    Inventor: Yerramilli V. S. N. Murthy
  • Methods, devices, kits and compositions for detecting roundworm
    Patent number: 8105795
    Abstract: Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: January 31, 2012
    Assignees: Idexx Laboratories, Inc., Divergence, Inc.
    Inventors: David Allen Elsemore, Laurie A. Flynn, Michael Crawford
  • Roundworm coproantigen detection
    Patent number: 8097261
    Abstract: A composition, device, kit and method for detecting the presence or absence of roundworm in a fecal sample. The composition, device, kit and method of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: January 17, 2012
    Assignee: Idexx Laboratories, Inc.
    Inventors: David Allen Elsemore, Laurie A. Flynn
  • Automated calibration method and system for a diagnostic analyzer
    Publication number: 20120005150
    Abstract: A method to track stability and performance of diagnostic instrumentation, especially for veterinary automated hematology analyzers, applies a weighted moving averages algorithm to the diagnostic results of patient samples calculated by the analyzer. Control chart rules are used to set limits or ranges in order to determine if weighted averaged diagnostic results are within or outside of such limits or ranges. If the weighted average diagnostic results are outside of such control chart rule limits, then fuzzy logic and a gradient descent algorithm are applied to the weighted averaged diagnostic results.
    Type: Application
    Filed: February 18, 2011
    Publication date: January 5, 2012
    Applicant: IDEXX Laboratories, Inc.
    Inventor: Jeremy Hammond
  • Anticoagulant-coated dipstick for use with a blood centrifuge rotor
    Patent number: 8021630
    Abstract: An anticoagulant-coated dipstick is selectively receivable by the central fill port of a rotor of a blood centrifuge. The dipstick includes an elongated, rod-like member having a first axial end and an opposite second axial end, and a cap affixed to the second axial end. At least a portion of a surface of the rod-like member is coated with an anticoagulant. The elongated rod-like member of the dipstick is dimensioned in length and diameter to be receivable through the central fill port of the rotor to contact a blood sample contained therein. The cap is circular in shape, with a diameter that is greater than that of the rotor fill port to entirely cover and seal the fill port to prevent leakage therethrough of a blood sample contained in the rotor, especially when the rotor is gently agitated or inverted.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: September 20, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventor: Alyssa J. Dassa
  • Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same
    Patent number: 8017159
    Abstract: The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of an aptamer and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: September 13, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventor: Yerramilli V. S. N. Murthy
  • Blood centrifuge rotor with fill indicator
    Patent number: 7993610
    Abstract: A spinnable rotor for a high speed centrifuge includes a housing which defines a chamber interiorly thereof for receiving a whole blood sample and for containing a predetermined amount of red blood cell absorbent gel. The housing includes an upper portion and a bottom portion, the upper portion having a port formed through the thickness thereof. The upper portion has at least a portion thereof formed from a light transmissible material. A light pipe is joined to the upper portion and light transmissively communicates with the light transmissive portion of the upper portion. The light pipe extends at least partially into the chamber and has an open, lower free end. When whole blood filling the rotor chamber contacts the lower free end of the light pipe, the red color of the blood is transmissively communicated to the upper portion of the rotor housing where it is viewable by the user of the centrifuge.
    Type: Grant
    Filed: October 2, 2006
    Date of Patent: August 9, 2011
    Assignee: IDEXX Laboratories, Incorporated
    Inventor: Carl Russell Rich
  • Methods, devices, kits and compositions for detecting whipworm
    Patent number: 7993861
    Abstract: Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of whipworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, roundworm, and heartworm. Confirmation of the presence or absence of whipworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: August 9, 2011
    Assignees: IDEXX Laboratories, Inc., Divergence, Inc.
    Inventors: David Allen Elsemore, Laurie A. Flynn, Michael Crawford
  • Methods, devices, kits and compositions for detecting roundworm
    Patent number: 7993862
    Abstract: Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: August 9, 2011
    Assignees: IDEXX Laboratories, Inc., Divergence, Inc.
    Inventors: David Allen Elsemore, Laurie A. Flynn, Michael Crawford
  • Method and Device for Detecting Feline Immunodeficiency Virus
    Publication number: 20110189651
    Abstract: A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV polypeptides and determining the binding of antibodies in the sample to the polypeptides. The determination of whether an animal is infected with FIV or has been vaccinated against FIV can be determined by measuring the animal's immune response to an FIV env polypeptide. A device for detecting FIV antibodies is provided.
    Type: Application
    Filed: April 15, 2010
    Publication date: August 4, 2011
    Applicant: IDEXX Laboratories, Inc.
    Inventors: Randall G. Groat, Quentin J. Tonelli
  • Compositions for Controlled Delivery of Pharmaceutically Active Compounds
    Publication number: 20110177157
    Abstract: Pharmaceutical compositions comprising (i) a dibasic amino acid ester or dibasic amino acid amide; (ii) a dicarboxylic acid; (iii) a pharmaceutically active compound or pharmaceutically acceptable salt thereof; and (iv) a pharmaceutically acceptable organic solvent. The pharmaceutical compositions form a depot when administered to an animal by injection that releases the pharmaceutically active compound over time.
    Type: Application
    Filed: December 23, 2010
    Publication date: July 21, 2011
    Applicant: IDEXX Laboratories, Inc.
    Inventor: Murthy V.S.N. Yerramilli
  • Fluoroquinolone carboxylic acid salt compositions
    Patent number: 7973022
    Abstract: The invention relates to pharmaceutical compositions that are a solution of a salt formed between a fluoroquinolone and a carboxylic acid, a cyclodextrin, and a pharmaceutically acceptable organic solvent and to methods of treating a condition in an animal by administering to an animal in need thereof the pharmaceutical composition of the invention.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: July 5, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventor: Yerramilli V. S. N. Murthy
  • Methods and compositions for detection of (VLPT)
    Patent number: 7964366
    Abstract: The invention provides methods and compositions for the detection of Ehrlichia chaffeensis.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: June 21, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Thomas Patrick O'Connor, Jr., Eugene Regis Krah, III, Jill M. Saucier
  • Methods, devices, kits and compositions for detecting roundworm, whipworm, and hookworm
    Patent number: 7951547
    Abstract: Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: May 31, 2011
    Assignees: Idexx Laboratories, Inc., Divergence, Inc.
    Inventors: David Allen Elsemore, Jinming Geng, Laurie A. Flynn, Michael Crawford
  • Detection of bovine viral diarrhea virus in hair samples
    Patent number: 7947438
    Abstract: The present invention relates to a method of detecting whether a target animal is Bovine Viral Diarrhea Virus (BVDV) positive or negative by determining whether a gp48 protein-specific reagent binds to a gp48 Bovine Viral Diarrhea Virus protein or protein fragment, which retains antigenic specificity, from a target animal's hair sample.
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: May 24, 2011
    Assignees: Cornell Research Foundation, Inc., IDEXX Laboratories
    Inventors: Roy Huchzermeier, Edward J. Dubovi
  • Detection of bovine viral diarrhea virus in tissue samples
    Patent number: 7947439
    Abstract: The present invention relates to a method of detecting whether a target animal is Bovine Viral Diarrhea Virus (BVDV) positive or negative by determining whether a gp48 protein-specific reagent binds to a gp48 Bovine Viral Diarrhea Virus protein or protein fragment, which retains antigenic specificity, from a target animal's tissue sample.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: May 24, 2011
    Assignees: Cornell Research Foundation, Inc., IDEXX Laboratories, Inc.
    Inventors: Roy Huchzermeier, Edward J. Dubovi
  • Methods and compositions for inhibiting binding of IgE to a high affinity receptor
    Patent number: 7931898
    Abstract: The invention provides methods and compositions for inhibiting binding of IgE to a high affinity receptor. The methods and compositions are useful in the treatment of allergic diseases and allergy symptoms in mammals.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: April 26, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Eugene Regis Krah, III, Robert Lawton
  • Macrolides Having Antibiotic Activity
    Publication number: 20110071096
    Abstract: The present invention relates to a semi-synthetic macrolide having antimicrobial activity, in particular antibacterial activity; pharmaceutical compositions comprising the macrolide; and methods of using the macrolide to treat or prevent an infection.
    Type: Application
    Filed: August 19, 2010
    Publication date: March 24, 2011
    Applicant: IDEXX Laboratories, Inc.
    Inventors: Murthy V.S.N. Yerramilli, Michael Randolph Atkinson, Hengguang Ll, Christopher Alan Cox
  • Animal identification band generator apparatus and method
    Patent number: 7908174
    Abstract: An animal tracking system integrated with a computerized animal management system operated by a microprocessor that maintains an animal information database of a plurality of animals within the custody of an animal handing facility, veterinary, pet kennel, or other pet care facility, includes an animal label driver that selectively generates an animal identification band having information associated with a selected one of the animals printed by a printer on a first surface with an attacher such as an opposing adhesive surface for attaching to the band in association with the animal. A method for generating an animal identification band by an animal management system is disclosed.
    Type: Grant
    Filed: December 17, 2005
    Date of Patent: March 15, 2011
    Assignee: Idexx Laboratories, Inc.
    Inventor: Dan G. Starko
  • Detection of
    Patent number: 7906296
    Abstract: The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: March 15, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Melissa Jane Beall, Phyllis Ione Tyrrell, Ramaswamy Chandrashekar, Jiayou Liu