Patents Assigned to Institute for Basic Science
  • Patent number: 10712479
    Abstract: A wavelength multiplexing device is disclosed. When light is irradiated on a first longitudinal end region of a metal nano-structure, surface plasmon polaritons are generated in the first longitudinal end region. The surface plasmon polaritons and the light are coupled with each other to form first coupled surface plasmon polaritons, wherein the first coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure. When the first coupled surface plasmon polaritons reach a two-dimensional material layer, excitons are induced in the two-dimensional material layer, wherein the induced excitons and the first coupled surface plasmon polaritons are coupled with each other to form second coupled surface plasmon polaritons. The second coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure toward a second longitudinal end thereof.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: July 14, 2020
    Assignees: Research & Business Foundation Sungkyunkwan University, Institute for Basic Science
    Inventors: Hyun Seok Lee, Young Hee Lee
  • Patent number: 10704099
    Abstract: The present invention relates to a method for determining a decrease in the functions of the hippocampus by using the correlation between a micro RNA (miRNA) and an N-methyl-D-aspartate receptor (NMDAR), a method for inhibiting the decrease in the functions, and a method for screening for inhibitors of the decrease in the functions.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: July 7, 2020
    Assignees: DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY, INSTITUTE FOR BASIC SCIENCE
    Inventors: Keetae Kim, Hong Gil Nam, Chand Parvez Danka Mohammed
  • Patent number: 10662206
    Abstract: The present invention relates to a method for preparing various silane derivatives by subjecting various furan derivatives to hydrosilylation in the presence of a borane catalyst. The method for preparing silane derivatives according to the present invention is a very efficient method for converting, into high value-added silane derivatives, various furan derivatives derived from biomass.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: May 26, 2020
    Assignees: INSTITUTE FOR BASIC SCIENCE, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sukbok Chang, Chinmoy Kumar Hazra, Narasimhulu Gandhamsetty
  • Patent number: 10639397
    Abstract: The present invention relates to a partial skull replacement consisting of polydimethylsiloxane (PDMS) and a method of monitoring biological tissues within a skull using the partial skull replacement. The method of monitoring using the partial skull replacement of the present invention has a minimal influence on intracranial pressure and cerebrospinal fluid flow as compared to a conventional cranial window technique using glass, and, by way of visualizing biological tissues within a skull with enhanced clarity, is expected to be usefully employed as a method of monitoring biological tissues within the skull.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: May 5, 2020
    Assignees: Research & Business Foundation Sungkyunkwan University, Institute for Basic Science
    Inventors: Seong-Gi Kim, Minah Suh, Chaejeong Heo, Hyoung Won Baac
  • Patent number: 10633696
    Abstract: The present disclosure provides a new protocol for sequencing the 3? end of messenger RNA (mRNA). The present disclosure can be very favorably used in analyzing the repetitive sequences of nucleic acids, which are difficult to analyze by current sequencing methods, especially, homopolymeric sequences (poly[A] sequence) of mRNA. The present disclosure has significantly improved sensitivity to mRNA compared with an existing method, thereby obtaining a lot of genetic information from a small amount of sample. The method of the present disclosure reduces the time and cost for sequencing the 3? end of mRNA and can be applied to various samples, and thus, can be used as a useful tool in the study of RNA synthesis/degradation and protein production in association with all life phenomena, including embryogenesis, cancer, and neurotransmission.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: April 28, 2020
    Assignees: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: V. Narry Kim, Jaechul Lim, Hyeshik Chang
  • Publication number: 20200110026
    Abstract: The present invention relates to a high-speed imaging system for measuring a target object within a sample, comprising: a light source emitting a plane wave; an angle-adjustment mirror adjusting an angle of the plane wave emitted from the light source; an optical interferometer dividing the plane wave whose angle was adjusted by the angle-adjustment mirror into a reference wave and a sample wave and forming an interference wave between the reference wave reflected from a reference mirror and the sample wave reflected from the target object; a camera module obtaining the interference wave, and an imaging controller controlling the angle-adjustment mirror to adjust the angle of the plane wave sequentially, forming a time-gated reflection matrix by using the interference waves obtained by the camera module in accordance with each angle of the plane wave, and imaging the target object based on the time-gated reflection matrix.
    Type: Application
    Filed: October 3, 2019
    Publication date: April 9, 2020
    Applicants: Korea University Research and Business Foundation, Institute For Basic Science
    Inventors: Won-Shik CHOI, Moon-Seok KIM, Yong-Hyeon JO, Seok-Chan YOON
  • Patent number: 10577465
    Abstract: The present invention relates to a silicon polymer production method using a non-transition-metal-catalyst method of hydrosilylation, and more specifically relates to a production method for a silicon polymer using a non-transition-metal-catalyst method of hydrosilylation, wherein an environmentally friendly silicon polymer is produced by using hydrosilylation using a non-transition metal as a catalyst, thereby avoiding the use of platinum, palladium and rhodium or other expensive platinum group catalysts and so achieving outstanding economic viability and making it possible to prevent residues of heavy metals.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: March 3, 2020
    Assignees: INSTITUTE FOR BASIC SCIENCE, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sukbok Chang, Seewon Joung, Dongwook Kim, Jeung Gon Kim
  • Patent number: 10564043
    Abstract: The present invention relates to a apparatus and method for measuring a waveform of a light wave. A light wave measurement apparatus according to an embodiment of the present invention includes a pulse separation unit to separate an input light wave into a fundamental pulse and a signal pulse, a time delay adjustment unit to adjust a time delay between the fundamental pulse and the signal pulse, a focusing unit to focus the fundamental pulse and the signal pulse whose time delay is adjusted on an ionization material, and an ionization yield measurement unit to measure an ionization yield from electrons and/or ions generated by the focused fundamental pulse and signal pulse. The waveform of the input light wave is obtained by obtaining an ionization yield modulation changed by the signal pulse as a function of the time delay.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: February 18, 2020
    Assignees: Institute For Basic Science, Gwangju Institute of Science And Technology
    Inventors: Kyung-Taec Kim, Chang-Hee Nam, Seung-Beom Park, Wo-Sik Cho, Kyung-Seung Kim
  • Patent number: 10543477
    Abstract: Provided are a polymer capsule loaded with transition metal particles having excellent water dispersibility and stability, and a method for preparing the same. Specifically, the polymer capsule loaded with transition metal particles according to the present invention includes a surface-modified polymer capsule surface-modified to thereby have a positive zeta potential in a dispersed state in water; and transition metal particles loaded on a surface of the surface-modified polymer capsule. In addition, a method for preparing a polymer capsule loaded with transition metal particles according to the present invention includes a) preparing a polymer capsule; b) surface-modifying the polymer capsule to prepare a polymer capsule having a positive zeta potential in a dispersed state in water; and c) sequentially adding a water-soluble transition metal precursor and a reducing agent to a water dispersion of the surface-modified polymer capsule obtained in step b).
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: January 28, 2020
    Assignees: INSTITUTE FOR BASIC SCIENCE, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Kimoon Kim, Gyeongwon Yun, Zahid Hassan, Jiyeong Lee, Jeehong Kim, Nam Hoon Kim, Kangkyun Baek, Ilha Hwang
  • Patent number: 10517963
    Abstract: Provided is a gene delivery including a polymer network formed by binding phenylboronic acid, sugar, and a low-molecular weight branched polymer. The gene delivery may be stably maintained in vivo and efficiently deliver a gene specifically to cancer cells, such that the gene delivery system may be usefully used as a gene delivery system for chemotherapy.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: December 31, 2019
    Assignees: Institute for Basic Science, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Won Jong Kim, Jinhwan Kim
  • Publication number: 20190333858
    Abstract: Provided is a dielectric layer that has a rock salt structure in a room temperature stable phase. The dielectric layer is made of a compound having a chemical formula of BexM1-xO, where M includes one of alkaline earth metals and x has a value greater than 0 and less than 0.5.
    Type: Application
    Filed: December 19, 2018
    Publication date: October 31, 2019
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INSTITUTE FOR BASIC SCIENCE, ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Seong Keun KIM, Woo Chul LEE, Sang Tae KIM, Hyun Cheol SONG, Seung Hyub BAEK, Ji Won CHOI, Jin Sang KIM, Chong Yun KANG, Christopher W. BIELAWSKI, Jung Hwan YUM, Eric S. LARSEN
  • Publication number: 20190200589
    Abstract: The present invention relates to: a transgenic Caenorhabditis elegans in which a glutamine tRNA 5? terminus-derived fragment (Gln 5?-tsRNA) is overexpressed; a preparation method therefor; and a method for screening for aging-associated factors by using the transgenic Caenorhabditis elegans. A transgenic Caenorhabditis elegans model provided in the present invention is an animal model in which Gln 5?-tsRNA is overexpressed such that aging is inhibited. When the model of the present invention is used, anti-aging mechanisms can be easily investigated, thereby significantly contributing to various research fields such as that of developing new anti-aging drugs and screening for age-inducing materials.
    Type: Application
    Filed: April 21, 2017
    Publication date: July 4, 2019
    Applicants: Postech Academy-Industry Foundation, Institute for Basic Science, Daegu Gyeongbuk Institute of Science
    Inventors: Hong Gil NAM, Gyoo Yeol JUNG, Seung Jae LEE, Woo Seon HWANG, Gi Won SHIN, Mi Hwa SEO
  • Patent number: 10301332
    Abstract: Provided is a method of controlling release of nitric oxide, and more particularly, to a method of selectively releasing nitric oxide depending on a change in pH using calcium phosphate. The method of selectively releasing nitric oxide according to the present invention may stably deliver nitric oxide to a desired site, and induce release of nitric oxide by a change in pH, thereby making it possible to improve a therapeutic effect while preventing a loss of nitric oxide.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: May 28, 2019
    Assignees: Institute for Basic Science, Postech Academy-Industry Foundation
    Inventors: Won Jong Kim, Jihoon Kim, Hyung Woo Choi
  • Patent number: 10280402
    Abstract: The present invention relates to a method for producing immune-compatible cells or a cell population which comprises a step of editing one or two alleles of one or more immune-compatible antigen genes by gene deletion or modification in an isolated cell comprising at least one of the immune-compatible antigen genes selected from HLA (human leukocyte antigen)-A, HLA-B and HLA-DR, to immune-compatible cells produced by the method, and to a cell population comprising the immune-compatible cells produced by the method.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: May 7, 2019
    Assignees: COLLEGE OF MEDICINE POCHON CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, INSTITUTE FOR BASIC SCIENCE
    Inventors: Jin Soo Kim, Dong Youn Hwang
  • Patent number: 10219779
    Abstract: An apparatus for generating a 3D left ventricle image includes: an ultrasonic sensor transmitting ultrasonic waves to the heart and receiving echoes thereof, an image processor acquiring a plurality of 2D left ventricle images based on the echoes of the ultrasonic waves and extracting sets of left ventricle boundary coordinates from the plurality of 2D images, respectively and a controller calculating a position of the left ventricle in 3D space through transformation of the sets of left ventricle boundary coordinates extracted by the image processor and generating a 3D left ventricle image based on the position of the left ventricle in 3D space.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: March 5, 2019
    Assignee: Institute for Basic Science
    Inventors: Chi Young Ahn, Ki Wan Jeon, Sang Woon Yun
  • Publication number: 20180353684
    Abstract: Provided are a biosensor and a method for forming the same, a glucose control system, a method for forming the glucose control system, and a method for controlling glucose using the glucose control system. The biosensor comprises at least one sensor comprising a sensing unit, a bridge unit connected to the sensing unit, and an electrode unit connected to the bridge unit, wherein the sensing unit comprises a graphene layer. The method for forming the biosensor that comprises at least one sensor comprising a sensing unit, a bridge unit connected to the sensing unit and an electrode unit connected to the bridge unit, comprises forming a lower insulation layer, forming a conductive electrode layer on the lower insulation layer, forming a graphene layer on the conductive electrode layer and forming a reaction layer on the graphene layer.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 13, 2018
    Applicants: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: Daehyeong KIM, Taeghwan HYEON, Seunghong CHOI, Hyunjae LEE, Taekyu CHOI
  • Patent number: 10082385
    Abstract: A system for measuring displacement of an accelerating tube by using a micro-alignment telescope, which includes a vacuum chamber; a hollow accelerating tube in the vacuum chamber; a sighting target attached to a surface of the accelerating tube while protruding from the surface of the accelerating tube; the micro-alignment telescope spaced apart from one side surface of the vacuum chamber; a first lens device interposed between the micro-alignment telescope and the vacuum chamber; and a second lens device spaced apart from an opposite side surface of the vacuum chamber by a distance, wherein the vacuum chamber includes first and second viewports placed on the surfaces of the vacuum chamber in correspondence with each other, and the micro-alignment telescope, the first lens device, the first viewport, the sighting target, the second viewport and the second lens device are aligned on a same axis in one direction.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: September 25, 2018
    Assignee: Institute for Basic Science
    Inventors: Min-Ki Lee, Young-Kwon Kim, Yong-Woo Jo, Jong-Wan Choi, Woo-Kang Kim, Hee-Tae Kim
  • Publication number: 20180266891
    Abstract: The present invention relates to a apparatus and method for measuring a waveform of a light wave. A light wave measurement apparatus according to an embodiment of the present invention includes a pulse separation unit to separate an input light wave into a fundamental pulse and a signal pulse, a time delay adjustment unit to adjust a time delay between the fundamental pulse and the signal pulse, a focusing unit to focus the fundamental pulse and the signal pulse whose time delay is adjusted on an ionization material, and an ionization yield measurement unit to measure an ionization yield from electrons and/or ions generated by the focused fundamental pulse and signal pulse. The waveform of the input light wave is obtained by obtaining an ionization yield modulation changed by the signal pulse as a function of the time delay.
    Type: Application
    Filed: May 17, 2018
    Publication date: September 20, 2018
    Applicants: Institute for Basic Science, Gwangju Institute of Science and Technology
    Inventors: Kyung-Taec KIM, Chang-Hee Nam, Seung-Beom Park, Wo-Sik Cho, Kyung-Seung Kim
  • Patent number: 10026913
    Abstract: A quantum dot electronic device comprises a first encapsulation layer, a first electrode disposed on the first encapsulation layer, a quantum dot pattern disposed on the first electrode, a second electrode disposed on the quantum dot pattern and a second encapsulation layer disposed on the second electrode. The quantum dot pattern may be formed by an intaglio transfer printing method, where the method comprises forming a quantum dot layer on a donor substrate, picking up the quantum dot layer using a stamp, putting the quantum dot layer into contact with an intaglio substrate using the stamp and separating the stamp from the intaglio substrate. Using the quantum dot transfer printing method, a subminiature quantum dot pattern can be transferred at a high transfer rate. Accordingly, a highly integrated quantum dot electronic device exhibiting excellent performance and a high integrated quantum dot light emitting device with an ultrathin film can be realized.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: July 17, 2018
    Assignees: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, INSTITUTE FOR BASIC SCIENCE
    Inventors: Daehyeong Kim, Taeghwan Hyeon, Moonkee Choi, Jiwoong Yang, Kwanghun Kang
  • Publication number: 20180145342
    Abstract: A flow field including graphene foam for a fuel cell. The flow field is made of graphene foam that enhances mass transport and suffers no corrosion under operating conditions of the fuel cell when compared with conventional flow fields. In addition, compressed graphene foam has smaller in-plane pores due to the compression and has more tortuous pathways for flowing reactants, thereby increasing retention time of reactants and accelerating diffusion of reactants into a gas diffusion layer (GDL). Further, large through-plane pores inside the graphene foam transport reactants to entire areas of a catalyst layer, and faster flow velocity compared with the conventional membrane electrode assembly (MEA) is derived from a decreased flow field width due to compression. Therefore, mass transport of reactants and products is enhanced, and performance of the fuel cell is improved at high current density regions.
    Type: Application
    Filed: November 16, 2017
    Publication date: May 24, 2018
    Applicants: Seoul National University, R&DB Foundation, Institute for Basic Science, Kangwon National University, University-Industry Cooperation Foundation
    Inventors: Yung-Eun SUNG, Yong-Hun CHO, Ji Eun PARK, Chi-Yeong AHN, Sungjun KIM