Abstract: Disclosed is a Processing-In-Sensor Accelerator (PISA) that provides a flexible, energy-efficient, and high-performance solution for real-time and smart image processing in AI devices. PISA implements a coarse-grained convolution operation in Binarized-Weight Neural Networks (BWNNs) leveraging a novel compute-pixel with non-volatile weight storage at the sensor side. This reduces power consumption of data conversion and transmission to an off-chip processor. A bit-wise near-sensor in-memory computing unit processes the remaining network layers. Once the object is detected, PISA switches to typical sensing mode to capture the image for a fine-grained convolution using only a near-sensor processing unit. The circuit-to-application co-simulation results on a BWNN acceleration demonstrate minor accuracy degradation on various image datasets in coarse-grained evaluation compared to baseline BWNN models. PISA achieves a frame rate of 1000 and efficiency of 1.74 TOp/s/W.

Abstract: The invention discloses a subwavelength grating based on bounds state in the continuum as the optical antenna for optical phased array, which includes a substrate and a grating layer atop the substrate. The grating layer includes a strip waveguide and sub-gratings symmetrically arranged on both sides of the strip waveguide. The sub-gratings may also be placed on different layers to build a multi-layer grating. The sub-grating excites the radiation modes, and destructive interference is formed between the sideward radiation modes by adjusting the width of the strip waveguide, which is used to establish the bounds state in the continuum. By designing the grating structure and adjusting the width of the strip waveguide, the invention establishes a diffraction-limited bound state in the continuum between sub-gratings to suppress sideward emission, thereby suppressing crosstalk between gratings, reducing the antenna pitch of the optical phased array, and increasing the phase-tuned beam steering range.

Abstract: Provided are a conductive nano thin film having an excellent flexibility while ensuring an electric conductivity, and exhibiting a favorable expansion and contraction in the thickness direction and the surface direction and a favorable conformability to a curved surface of the body and to shape deformation; and a dielectric elastomer actuator using such conductive nano thin film. The conductive nano thin film of the present invention includes an elastomer layer and a carbon nanotube layer laminated on at least one surface of the elastomer layer, and the conductive nano thin film has a film thickness of smaller than 1,000 nm. The dielectric elastomer actuator of the present invention has the conductive nano thin film as an electrode.

Abstract: Disclosed herein are trogocytosis based TCR ligand discovery platforms and methods of using the same, trogocytosis based TCR discovery platforms and methods of using the same, and trogocytosis based ligand discovery platforms and methods of using the same. Also disclosed herein are isolated cells, nucleotides, sequences, and sequence databases produced using trogocytosis based discovery platforms.

Abstract: The disclosure provides various systems and methods for identifying individuals from one or more samples. In particular, improved systems and methods of analysis are provided for handling multiple contributors, as well as systems and methods that model not only individual error rates per locus but factor in amplification of errors induced through PCR cycles. In some embodiments, modeling of error rates can be applied in multi-contributor settings to more accurately establish real alleles from artifacts. Other aspects involve application of sequencing in error modeling. Further, methods are provided for determining the presence of common individual DNA profiles in one or more complex DNA mixtures and for deconvolution of multiple complex DNA mixtures into shared individual components. The methods of the disclosure do not require any prior knowledge of individual DNA profiles or contributors to the complex DNA mixtures.

Abstract: A base pathway of a computerized two-pathway video action recognition model is trained using a plurality of labeled video samples. The base pathway is trained using a plurality of unlabeled video samples at a first framerate. An auxiliary pathway of the computerized two-pathway video action recognition model is trained using a plurality of the unlabeled video samples at a second framerate, the second framerate being slower than the first framerate, wherein the training of the base pathway and the training of the auxiliary pathway result in a trained computerized two-pathway video action recognition model. A candidate video is categorized using the trained computerized two-pathway video action recognition model and the categorized candidate video is stored in a computer-accessible video database system for information retrieval.

Abstract: Articles and methods for the active transport of molecules into, within, and/or from a matrix are generally described. In some embodiments, an electric field may be used to alter the position of the molecule with respect to the matrix. The electric field may be used to move the molecule to a new location within the matrix, remove the molecule from the matrix, or infuse the molecule into the matrix. For instance, the electric field may be used to move a molecule having a binding partner within the matrix into or away from the vicinity of the binding partner. In some embodiments, the position of the molecule may be altered by exposing the molecule to an electrodynamic field. In some such embodiments, the molecule exposed to the dynamic electric field may have enhanced mobility and minimal adverse matrix interactions relative to conventional molecular transport methods, and in some cases, a molecule exposed to an electrostatic field.

Abstract: High-power light absorbers (HPLAs) can exhibit low back-scattered light, mitigate stray light, and withstand high optical power. The absorbers can be used with or without baffling as beam dumps for high-power lasers. An HPLA may include a substrate made of high thermally conductive material with an anti-reflection (AR) coating formed on the substrate. A thin layer of highly absorbing material may be located between the AR coating and substrate. The substrate can be cooled with a fluid, such as water or air.

Abstract: A sensorless commutation error compensation system for a brushless motor, comprises: a brushless motor (200) and a commutation logic module circuit (100). The commutation logic module circuit (100) is connected to three virtual Hall signal output ends of the brushless motor (200), and used for receiving three virtual Hall signals output by the brushless motor (200), obtaining three error compensation angle signals on the basis of the three virtual Hall signals, respectively superimposing the three error compensation angle signals and the three virtual Hall signals to form superposition results, and controlling the brushless motor (200) to adjust commutation timing on the basis of the superposition results, so as to achieve commutation error compensation.

Abstract: Components with relatively high loading of active pharmaceutical ingredients (e.g., drugs), are generally provided. In some embodiments, the component (e.g., a tissue interfacing component) comprises a solid therapeutic agent (e.g., a solid API) and a supporting material (e.g., a binder such as a polymer) such that the solid therapeutic agent is present in the component in an amount of greater than or equal to 10 wt % versus the total weight of the tissue interfacing component. Such tissue-interfacing components may be useful for delivery of API doses e.g., to a subject. Advantageously, in some embodiments, the reduction of volume required to deliver the required API dose as compared to a liquid formulation permits the creation of solid needle delivery systems for a wide variety of drugs in a variety of places/tissues (e.g., tongue, GI mucosal tissue, skin) and/or reduces and/or eliminates the application of an external force in order to inject a drug solution through the small opening in the needle.

Abstract: Disclosed are methods, systems, cells and compositions directed to modeling a physiologic or pathologic process in an animal using a set of yeast genes analogous to a set of animal genes and augmenting the physiologic or pathologic process in the animal with predicted gene interactions based on the interactions between the set of yeast genes. Also disclosed are methods of screening for and using therapeutics for neurodegenerative proteinopathies.

Abstract: Systems and methods for assessment of lipid membrane-associated molecules are described. Generally, a system can comprise a scaffold with a molecule attached thereon. The scaffold can comprise a plurality of hydrophobic seeds to form a liposome. The molecule attached to the scaffold can integrate into the formed liposome and then be released from the scaffold. The kinetics, dynamics, and interactions of the molecule within the liposome can be detected or monitored.

Abstract: An information processing system includes a processor that performs an object detection to detect an object from a detection target image. The processor divides the detection target image into a group of first grid cells. The object is positioned to overlap a group of second grid cells included in the group of the first grid cells. At this time, the processor generates a bounding box in a respective second grid cell included in the group of the second grid cells. The processor surrounds a portion of the object positioned in the respective second grid cell with the bounding box generated in the respective second grid cell and displays, on a display, a position and shape of the object by a collection of a plurality of bounding boxes superimposedly on the detection target image.

Abstract: Provided herein are compositions and methods for enhancing the activity of Stimulator of Interferon Genes (STING) with one or more agents for inhibiting the activity of one or more negative regulators of STING, including DNAJC13 and ESCRT.

Abstract: An object of the present invention to realize a step of producing an environmentally friendly textile product using a solvent in place of conventionally used water or an organic solvent in a textile product scouring step. A method according to one aspect of the present invention includes a step (a) of bringing a fluid containing supercritical carbon dioxide into contact with the textile product to remove part or all substances adhered to a surface of the textile product.

Abstract: Quantum teleportation is essential for many quantum information technologies, including long-distance quantum networks. Using fiber-coupled devices, including state-of-the-art low-noise superconducting nanowire single-photon detectors and off-the-shelf optics, we achieve conditional quantum teleportation of time-bin qubits at the telecommunication wavelength of 1536.5 nm. We measure teleportation fidelities of ?9% that are consistent with an analytical model of our system, which includes realistic imperfections. To demonstrate the compatibility of our setup with deployed quantum networks, we teleport qubits over 22 km of single-mode fiber while transmitting qubits over an additional 22 km of fiber. Our systems, which are compatible with emerging solid-state quantum devices, provide a realistic foundation for a high-fidelity quantum Internet with practical devices.

Abstract: Systems and methods related to aluminum-water reactions, hydrogen gas production, and the recovery of activating metals are generally described.

Abstract: A closed leak-free, diffusion-blocking one-way check valve is composed of a substrate having a flow passage through the substrate, the flow passage has a sealing surface between the substrate and a membrane preventing flow through the flow passage. A thin film having internal stress is disposed on the membrane which induces deformation of the membrane biasing the membrane resulting in the sealing surface in a closed orientation. A method for fabrication and pump utilizing the check valve are disclosed.

Abstract: Systems, methods, and other embodiments described herein relate to enhancing and complementing a creative process of a user that includes generating and iterating visual content with an emphasis on diverse design ideas. In one embodiment, a method includes generating a plurality of texts that are related and semantically diverse based on one or more prompts using a generative language model and generating a plurality of images based on at least a portion of the plurality of texts using a generative visual model.

Abstract: Electrochemical devices, and associated materials and methods, are generally described. In some embodiments, an electrochemical device comprises an electroactive material. The electroactive material may comprise an alloy having a solid phase and a liquid phase that co-exist with each other. As a result, such a composite electrode may have, in some cases, the mechanical softness to permit both high energy densities and an improved current density as compared to, for example, a substantially pure metal electrode.