Abstract: A system for reconstructing a magnetic particle image based on adaptive optimization of regularization terms includes: a MPI device for scanning an imaging object to acquire a voltage response signal; a signal processor for constructing a system matrix; and a control processor for reconstructing the magnetic particle image based on an arbitrarily selected regularization term, inputting the reconstructed magnetic particle image to a regularization-term adaptive optimization neural network model for enhancement processing, taking the enhanced magnetic particle image as a first image, and calculating a loss value between the first image and an initial image to acquire a final reconstructed magnetic particle image. The system adopts a neural network model-based automatic learning approach, instead of the approach of manually selecting regularization terms and adjusting parameters, to improve the reconstruction efficiency and quality of the magnetic particle image.

Abstract: Systems and methods are provided for improving a localization estimate of a vehicle by leveraging localization estimates of surrounding vehicles. A vehicle may estimate its own location relative to a global reference frame. The vehicle may identify nearby vehicles. The vehicle may estimate the location of the nearby vehicles. The vehicle and nearby vehicles may generate and exchange localization packets containing information about the vehicles and the location estimates. The vehicle may refine its localization estimate based on received localization packets.

Abstract: A gas replacement process and a gas replacement apparatus are employed, in the nitro compound hydrogenation reaction process. The gas replacement process at least includes a first step of subjecting a stream to be replaced to the gas replacement in presence of a first replacement gas, and then a second step of subjecting to the gas replacement in presence of the second replacement gas. Assuming the superficial velocity of the first replacement gas is V1, and the superficial velocity of the second replacement gas is V2, then V2/V1?1.5.

Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method of decoding an image includes receiving a bitstream in which the image is encoded; obtaining index information for specifying a block division type of a current block in the image; and determining the block division type of the current block from a candidate group pre-defined in the decoding apparatus. The candidate group includes a plurality of candidate division types, including at least one of a non-division, a first quad-division, a second quad-division, a binary-division or a triple-division. The method also includes dividing the current block into a plurality of sub-blocks; and decoding each of the sub-blocks with reference to syntax information obtained from the bitstream.

Abstract: A compound midazolam-D3 and its preparation method as it's synthesized from 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (Compound II), by ring closure reaction with ethyl isocyanoacetate, hydrolysis with base, ring-opening with acid, ring closure under high temperature, and reacted with trideuteromethyl reagent; the synthetic route has advantage of short synthetic route appropriate, accessible and affordable. The prepared midazolam-D3 has characteristic with high purity, high deuterium content and very good stability.

Abstract: Disclosed is a camouflage pattern forming device, which includes a communication unit that receives first data including a location of an observer from an external device, an information collection unit that collects second data including images for each of a plurality of wavelength bands in external environment, a pattern forming unit that forms pattern data of the plurality of wavelength bands by performing machine learning based on the first data, the second data, and third data including camouflage pattern data for each environment, and a display unit that receives the pattern data from the pattern forming unit to form and display a camouflage patterns of the plurality of wavelength bands, and the display unit includes a display device and a heat generator capable of adjusting a heat emissivity.

Abstract: A method for extracting and correcting a ringing component in a dynamic pressure measurement signal of a shock wave flow field includes: adaptively decomposing a dynamic pressure measurement signal of a shock wave flow field through an empirical mode decomposition (EMD) method, and extracting a ringing component in the dynamic pressure measurement signal of the shock wave flow field; constructing a ringing component distortion correction model through a convolutional neural network (CNN) and a dataset through a staggered spanning dataset construction method; and predicting a time series of a segment with mode mixing in the ringing component, to accurately extract a ringing component in a dynamic pressure response signal. The method combines advantages of an adaptive signal decomposition method and a CNN model identification method.

Abstract: A method of forming a federated digital twin and a digital twin for performing the method are disclosed. The digital twin includes general functions (GF) configured to provide a function and data of the digital twin and federation orchestration functions (FOF), wherein the FOF are configured to discover one or more other digital twins to federate with the digital twin, determine, from among the discovered digital twins, a digital twin to form a federated digital twin, and form the federated digital twin by establishing a communication connection with the determined digital twin.

Abstract: Disclosed are bifunctional compounds (degraders) that target ALK for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the bifunctional compounds to treat diseases and disorders characterized or mediated by aberrant ALK activity.

Abstract: A planar transparent antenna structure is provided. The planar transparent antenna structure includes a dielectric substrate, a radiation patch conductive layer, a parasitic patch conductive layer and a ground conductive layer. The radiation patch conductive layer is disposed on the dielectric substrate. The radiation patch conductive layer is a ring structure. The parasitic patch conductive layer is disposed on the dielectric substrate. The ground conductive layer is disposed on the dielectric substrate. The radiation patch conductive layer, the parasitic patch conductive layer and the ground conductive layer are composed of a plurality of wires interconnected and connected with each other and are light-transmissive.

Abstract: The present disclosure relates to a method and an apparatus for processing accelerated test data based on multiple performance degradation, and a device.

Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method of decoding an image includes receiving a bitstream in which the image is encoded; obtaining index information for specifying a block division type of a current block in the image; and determining the block division type of the current block from a candidate group pre-defined in the decoding apparatus. The candidate group includes a plurality of candidate division types, including at least one of a non-division, a first quad-division, a second quad-division, a binary-division or a triple-division. The method also includes dividing the current block into a plurality of sub-blocks; and decoding each of the sub-blocks with reference to syntax information obtained from the bitstream.

Abstract: The present invention relates to: a novel chimeric antigen receptor containing, as an intracellular signaling domain, an intracellular domain of a receptor containing a dead region; and immune cells expressing the chimeric antigen receptor. In environments in which normal cells are present, the immune cells expressing the chimeric antigen receptor according to the present invention exhibit little or no cytotoxicity and cell death of the immune cells is exhibited, thus ensuring the stability of the normal cells. Conversely, in environments in which target cells are present, the immune cells exhibit more potent cytotoxicity than with conventional techniques utilizing a lone chimeric antigen receptor.

Abstract: Disclosed is an optical pulse adjusting device including a pulse shaper that receives an input signal generated based on an optical frequency comb (OFC) signal and outputs a spectrum adjustment signal by adjusting an optical spectrum shape of the input signal, an optical amplifier that outputs an optical amplification signal by amplifying the spectrum adjustment signal, an optical spectrum analyzer (OSA) that outputs an information signal by comparing an optical spectrum shape of the optical amplification signal with a target optical spectrum shape, and a control circuit that outputs a comparison signal based on the information signal. The pulse shaper further receives the comparison signal and adjusts the optical spectrum shape of the input signal based on information about a difference between the optical spectrum shape of the optical amplification signal and the target optical spectrum shape, which is included in the comparison signal.

Abstract: Disclosed are deubiquitinase (DUB) JOSD1 inhibitors and methods of treating a disease or disorder mediated by dysregulated Janus Kinase 2 (JAK2) activity, in a subject in need thereof, comprising administering a therapeutically effective amount of one or more DUB inhibitors.

Abstract: A planar transparent antenna structure is provided. The planar transparent antenna structure includes a dielectric substrate, a radiation conductive layer and a ground conductive layer. The dielectric substrate has a first surface and a second surface. The radiation conductive layer is disposed on the first surface of the dielectric substrate. The ground conductive layer is disposed on the second surface of the dielectric substrate. The radiation conductive layer and the ground conductive layer are composed of a plurality of wires connected in a mesh manner. Each of the wires is composed of a plurality of grid lines connected in a mesh manner.

Abstract: A copolyester is formed by reacting 100 parts by weight of a polyester elastomer and 0.01 to 0.29 parts by weight of a compound having multi-functional groups. The polyester elastomer is formed by reacting polyethylene terephthalate, diol, and poly(alkylene ether)glycol. The polyethylene terephthalate and the diol have a weight ratio of 1:0.6 to 1:3, and the polyethylene terephthalate and the poly(alkylene ether) glycol have a weight ratio of 1:0.05 to 1:3.

Abstract: Disclosed is a method of treating cancer with a compound that possesses degradation activity against SMARCA4/2 in combination with a DOT1L r inhibitor.

Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method of decoding an image includes receiving a bitstream in which the image is encoded; obtaining index information for specifying a block division type of a current block in the image; and determining the block division type of the current block from a candidate group pre-defined in the decoding apparatus. The candidate group includes a plurality of candidate division types, including at least one of a non-division, a first quad-division, a second quad-division, a binary-division or a triple-division. The method also includes dividing the current block into a plurality of sub-blocks; and decoding each of the sub-blocks with reference to syntax information obtained from the bitstream.

Abstract: The present invention relates to a method for monitoring the quality of red pepper powder, comprising the steps of: estimating at least one of a first particle size and a first moisture content of a first red pepper powder, based on the spectroscopic image data of the first red pepper powder obtained in or before and after at least one of the grinding process, filtration process and sterilization process of red pepper powder; calculating a second spicy level, based on at least one of the first particle size and the first moisture content, and the spectroscopic image data; and estimating a third spicy level of a first mixed red pepper powder in the mixing process, based on at least one of the first particle size and the first moisture content, the second spicy level, and an input amount of the first red pepper powder.