Abstract: The present invention discloses a nanobody targeting IL-6R? protein and uses thereof, wherein the heavy chain variable region of the nanobody comprises three complementary determining regions, CDR1, CDR2, and CDR3, wherein CDR1 has an amino acid sequence as shown in SEQ ID NO. 2, CDR2 has an amino acid sequence as shown in SEQ ID NO. 3, and CDR3 has an amino acid sequence as shown in SEQ ID NO. 4. With high affinity to IL-6R? protein and high stability and water solubility, the nanobody can be used in the development of pharmaceutical compositions for the treatment of IL-6-mediated related diseases or conditions, as well as in the development of reagents or kits for the detection of IL-6R?, which can provide potentially highly effective antibodies for the study of IL-6-mediated related diseases, and provide new therapeutic strategies and targets for autoimmune diseases or tumors.

Abstract: The present invention relates to the use of Raman spectroscopy for the real time detection and quantitation of innate immunity response in plants. More specifically, the present invention provides Raman spectroscopy as a tool for rapid, non-invasive, and early detection and quantitation of plant innate immune response.

Abstract: A manufacturing method for an electron source according to the present disclosure includes steps of: (A) cutting out a chip from a block of an electron emission material, (B) fixing a first end portion of the chip to a distal end of a support needle, and (C) sharpening a second end portion of the chip. The step (A) includes forming first and second grooves which constitute first and second surfaces of the chip in the block by irradiating a surface of the block with an ion beam. The first end portion of the chip includes the first surface and the second surface with the surfaces forming an angle ? of 10 to 90°. The step (B) includes forming a joint between the distal end of the support needle and the first end portion of the chip.

Abstract: Disclosed are a method of encoding a division block in video encoding and a method of decoding a division block in video decoding. An input picture is divided into encoding unit blocks. The encoding unit blocks are divided into sub-blocks. The sub-blocks are encoded by selectively using at least one of intra prediction encoding and inter prediction encoding. A decoding process is performed through a reverse process of the encoding method. When pixel values of an encoding unit block are encoded in video encoding, the flexibility in selecting an encoding mode is increased and the efficiency of encoding is increased.

Abstract: The present disclosure provides a speaker box structure and an electronic device. The speaker box structure includes a speaker box housing, a sound guiding member, a high-pitched speaker, and a mid-bass speaker. The sound guiding member is installed on the speaker box housing, and the sound guiding member forms a high-pitched sound guiding channel and a mid-bass sound guiding channel at intervals. Both the high-pitched sound guiding channel and the mid-bass sound guiding channel have a sound inlet facing the speaker box housing and a sound outlet facing away from the speaker box housing. The high-pitched speaker is disposed on the speaker box housing and is opposite to the sound inlet of the high-pitched sound guiding channel, and the mid-bass speaker is disposed on the speaker box housing and is opposite to the sound inlet of the mid-bass sound guiding channel.

Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method of decoding an image includes receiving a bitstream in which the image is encoded; obtaining index information for specifying a block division type of a current block in the image; and determining the block division type of the current block from a candidate group pre-defined in the decoding apparatus. The candidate group includes a plurality of candidate division types, including at least one of a non-division, a first quad-division, a second quad-division, a binary-division or a triple-division. The method also includes dividing the current block into a plurality of sub-blocks; and decoding each of the sub-blocks with reference to syntax information obtained from the bitstream.

Abstract: The present disclosure relates to compositions, methods and kits for enhancing ribosomal activities in a host cell, especially improvement of the translation activity of heterologous ribosomes within a host cell. Specifically, the instant disclosure provides a number of evolved rRNA sequences, which were remarkably identified to possess enhanced translation activities, improved orthogonal-ribosome binding site (o-RBS) and orthogonal anti-ribosome binding site (o-antiRBS) sequences, host cells possessing deletion or disruption of ribosome hibernation promoting factor (HPF) that thereby exhibit enhanced propagation of selection phage constructs during (PACE), among other aspects. New transgenic organisms harboring heterologous ribosomes and operons are also provided.

Abstract: Disclosed herein are a method, an apparatus, and a storage medium for image encoding/decoding using geometric partitioning. A target block may be geometrically partitioned, and multiple partitioned regions may be generated from geometric partitioning. Each partitioned region may have a non-square and a non-rectangular shape. Different prediction schemes may be applied to different partitioned regions. The different prediction schemes for multiple partitioned regions may be signaled as explicit information, and may be derived using information about a coding parameter for the target block or the like.

Abstract: A method and a device for encoding/decoding an image according to the present invention may determine a reference region for intra prediction of a current block, derive an intra prediction mode of the current block on the basis of a predetermined MPM candidate group, and perform intra prediction on the current block on the basis of the reference region and the intra prediction mode.

Abstract: Provided is a quantum circuit, a quantum computing element, a quantum computing system, and a quantum computing method with which physical reservoir computing with high learning efficiency becomes possible.

Abstract: An oxygen generator with an oxygen-producing having a center bore, including: an impact-activated ignition mechanism, an end cover, a cylinder, a bell-shaped hood, a thermally insulating inner cylinder, an oxygen-producing column, a thermally insulating material, a support bowl, a gas purification material, a safety valve, an isolation net, an oxygen-discharging end cover and an oxygen-discharging joint. The cylinder is provided with the end cover at one end; the impact-activated ignition mechanism is fixed on the end cover; the oxygen-producing column is coaxially located with the cylinder, one end of the oxygen-producing column is connected to the impact-activated ignition mechanism, and the other end of the oxygen-producing column is connected to the support bowl; the support bowl is connected to the isolation net; the thermally insulating inner cylinder is arranged on the outside of the oxygen-producing column and the thermally insulating material.

Abstract: A method of decoding an image, includes obtaining at least one offset for a picture, deriving a variable for scaling for the picture based on the at least one offset, and performing inter prediction based on the variable for scaling for the picture. The at least one offset is defined with a direction of scaling.

Abstract: The present disclosure provides a technology field of caking of crystal particles, and in particular relates to a method for predicting a critical caking cycle of crystal particle. The method includes: establishing a CHS crystal bridge growth model database of a crystal particle with a same type of crystal particle to be predicted firstly, selecting existed data in the corresponding CHS crystal bridge growth model database based on an equivalent particle radius, a stored ambient temperature, and an environmental high and low humidity cycle condition of the crystal particle to be predicted, respectively, and calculating the critical caking cycle according to experience calculation equations, wherein a result obtained by calculation is a predicted critical caking cycle of the crystal particle to be predicted.

Abstract: A method and a device for encoding/decoding an image according to the present invention may determine a reference region for intra prediction of a current block, derive an intra prediction mode of the current block on the basis of a predetermined MPM candidate group, and perform intra prediction on the current block on the basis of the reference region and the intra prediction mode.

Abstract: A pyrimidine derivative, a method for preparing the pyrimidine derivative, and a pharmaceutical composition comprising the pyrimidine derivative are disclosed. Also disclosed is a method for preventing or treating cancer which includes administering the pyrimidine derivative or a composition containing the pyrimidine derivative to a subject in need of cancer treatment or prevention.

Abstract: A method and a device for encoding/decoding an image according to the present invention may determine a reference region for intra prediction of a current block, derive an intra prediction mode of the current block on the basis of a predetermined MPM candidate group, and perform intra prediction on the current block on the basis of the reference region and the intra prediction mode.

Abstract: A semiconductor integrated circuit device includes a resistive layer having a trench-like structure with an upward opening, a first electrode located on an outer side of the resistive layer, and a second electrode located on an inner side of the resistive layer; the first electrode and the second electrode are opposite to each other on two sides of a sidewall of the resistive layer; and the resistive layer, the first electrode and the second electrode form a first memory cell. A manufacturing method includes forming a first electrode on a substrate, the substrate including a first via connected with a first metal layer; etching a recess in the first electrode at a position staggered from the first via and forming a resistive layer in the recess; and forming a second electrode in the opening of the resistive layer to obtain a first memory cell.

Abstract: The present invention relates to a metal-organic hybrid lattice material and the application in the detection of radiation sources. In the invention, a water-soluble thorium salt and 2,2?:6?,2?-terpyridine-4?-carboxylic acid are subjected to a solvothermal reaction in water and an organic mixed solvent to obtain a metal-organic hybrid lattice material. The crystalline material produces radiation-induced discoloration and photoluminescence change under ultraviolet light, X-ray, ?-ray, ?-ray, and so on. The material is useful for qualitative and quantitative detection and calibration after high-dose irradiation. Compared with the traditional radiation-induced color change indicator labels, the material achieves the visual qualitative and quantitative detection and has strong radiation stability, high reuse rate, wide detection range, and good linear relationship, to solve the problem of traditional materials relying on professional optical equipment to quantify the radiation dose.

Abstract: Disclosed are a transition metal chalcogenide thin-layer material, a preparation method and an application thereof. The preparation method comprises: uniformly spreading a transition metal source between two substrates to prepare a sandwich structure; performing a heat treatment on the sandwich structure to fuse and bond the two substrates together, and performing a chemical vapor deposition reaction on a chalcogen element source and the fused and bonded sandwich structure under the protection of a protective gas, wherein the transition metal source is heated to dissolve and diffuse at a reaction temperature, separated out from surfaces of the substrates, and reacts with the chalcogen element source. The prepared thin-layer material is uniformly distributed in a centimeter-level substrate.

Abstract: A pixel circuit may comprise: a first transistor having a first terminal connected to a data line and to which a data signal is applied and a gate terminal connected to a scan line and to which a scan signal is applied; a third transistor having a gate terminal connected to a second terminal of the first transistor and a second terminal connected to a light emitting device; a capacitor having a second terminal commonly connected to the second terminal of the first transistor and the gate terminal of the third transistor; and a second transistor having a second terminal commonly connected to a first terminal of the capacitor and a first terminal of the third transistor, a first terminal connected to a first power supply voltage, and a gate terminal connected to an emission line to which an emission signal is applied.