Abstract: Geospatial data can be converted into audio outputs. For example, a system can receive a dataset indicating geospatial locations of objects within a region. Based on the dataset, the system can generate a virtual map representing the region and including virtual points representing the objects. The virtual points can be spatially positioned at locations in the virtual map corresponding to the geospatial locations of the objects in the region. The system can receive a user input via a user input device for interacting with a particular virtual point among the virtual points in the virtual map. The system can determine one or more sound characteristics for a sound based on receiving the user input. The system can then transmit an audio signal to an audio device for causing the audio device to generate the sound having the one or more sound characteristics, which may assist with exploring the virtual map.
Type:
Grant
Filed:
August 24, 2020
Date of Patent:
February 22, 2022
Assignee:
SAS INSTITUTE INC.
Inventors:
Claude Edward Summers, II, Sean Patrick Mealin, Julianna Elizabeth Langston, Gregory David Kraus, Jonathan Tyler Williamson, Lisa Beth Morton Robinson, Jesse Daniel Sookne, Brice Joseph Smith
Abstract: A new column-based purification system and approach are described for rapid separation and purification of the alpha-emitting therapeutic radioisotope 211At from dissolved cyclotron targets that provide highly reproducible product results with excellent 211At species distributions and high antibody labeling yields compared with prior art manual extraction results of the prior art that can be expected to enable enhanced production of purified 211At isotope products suitable for therapeutic medical applications such as treatment of cancer in human patients.
Abstract: A method for manufacturing a semiconductor device is provided. A first substrate and at least one second substrate are provided. A single crystal lamination structure is formed on the first substrate. The single crystal lamination structure includes at least one hetero-material layer and at least one channel material layer that are alternately laminated, each of the at least one hetero-material layer is bonded to an adjacent one of the at least one channel material layer at a side away from the first substrate, and each of the at least one channel material layer is formed from one of the at least one second substrate. At least one layer of nanowire or nanosheet is formed from the single crystal lamination structure. A gate dielectric layer and a gate which surround each of the at least one layer of nanowire or nanosheet is formed. A semiconductor device is also provided.
Type:
Grant
Filed:
September 23, 2020
Date of Patent:
February 22, 2022
Assignee:
Institute of Microelectronics, Chinese Academy
Abstract: The present invention relates to a nanocarrier peptide sequence (SEQ ID NO: 6 KXPXXXXA/V/GXGNXX; wherein X is selected from amino acid R, K, A or H. The present invention also relates to the method for cellular delivery, by implementing the steps of: complexation of a peptide nanocarrier sequence: KXPXXXXA/V/GXGNXX; where X is selected from amino acid R,K,A and H having SEQ ID NO: 6 with a macromolecule to obtain a complex; and administering the complex to a targeted mammalian or plant cell or tissue.
Abstract: A cell culture module, a cell culture system and a cell culture method are provided. The cell culture module includes a casing, a first fixer, a second fixer and a sheet-shaped carrier member. The casing has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the casing and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. The sheet-shaped carrier member is formed by arranging a plurality of cell culture carriers, and two opposite ends of the sheet-shaped carrier member are respectively fixed to the first fixer and the second fixer. The sheet-shaped carrier member is in an open state or a folded state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
February 22, 2022
Assignee:
Industrial Technology Research Institute
Abstract: Disclosed herein are a magnetic-field-generating coil system, an imaging system having the magnetic-field-generating coil system, and a method for operating the imaging system. The method for operating an imaging system includes generating multiple Linear Gradient Fields (LGFs) in respective axial directions by controlling coil currents, and acquiring MRI information or Magnetic Particle Imaging (MPI) information about an object while moving the multiple LGFs by varying the coil currents.
Type:
Grant
Filed:
September 16, 2019
Date of Patent:
February 22, 2022
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Hyo-Bong Hong, Jae-Chan Jeong, Seung-Min Choi, Jin-Sun Kim
Abstract: A method for synthesizing parameters for control of a closed loop system based on a differentiable simulation model of the closed loop system includes determining requirements/specifications for the closed loop system in signal temporal logic (STL). The method also includes selecting a parametric control law having a differentiable parameter control function. The method also includes converting the requirements in signal temporal logic into differentiable computational graph. The method further includes building the differentiable simulation model as a differentiable computational graph. Furthermore, the method includes automatically learning values of parameters for the differentiable parameter control function of the closed loop system by backpropagating an error.
Type:
Grant
Filed:
May 29, 2019
Date of Patent:
February 22, 2022
Assignees:
TOYOTA RESEARCH INSTITUTE, INC., THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Inventors:
Nikos Arechiga Gonzalez, Karen Y. Leung, Soon Ho Kong, Jonathan Decastro, Frank Permenter
Abstract: Provided is a wireless communication terminal that communicates wirelessly. The terminal includes: a transceiver; and a processor. The processor is configured to receive a Downlink Multi-User (DL MU) PPDU including information for an Uplink Multi-User (UL MU) transmission from a base wireless communication terminal by using the transceiver, and transmit the UL MU PPDU to the base wireless communication terminal based on the information for UL MU transmission.
Type:
Grant
Filed:
April 17, 2020
Date of Patent:
February 22, 2022
Assignees:
WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., SK TELECOM CO., LTD.
Abstract: A lithium metal pouch cell having a specific energy ?300 Wh·kg?1 includes an anode comprising lithium metal and an anode current collector, the anode having an areal capacity N (mAh·cm?2); a cathode comprising a cathode material and a cathode current collector, the cathode having an a real capacity P (mAh·cm?2), wherein a ratio of N/P is within a range of 0.02 to 5; an electrolyte having an electrolyte mass E and comprising a lithium active salt and a solvent, the lithium metal pouch cell having an electrolyte mass to cell capacity (E/C) ratio within a range of 1 to 6 g·Ah?1; a separator positioned between the anode and the cathode; and a packaging material defining a pouch enclosing the anode, cathode, electrolyte, and separator; wherein a protruding tab of the anode current collector and a protruding tab of the cathode current collector are external to the pouch.
Type:
Application
Filed:
October 27, 2021
Publication date:
February 17, 2022
Applicant:
Battelle Memorial Institute
Inventors:
Jie Xiao, Jun Liu, Hongkyung Lee, Dianying Liu, Chaojiang Niu
Abstract: A method of decoding an image, includes obtaining at least one offset for a picture, deriving a variable for scaling for the picture based on the at least one offset, and performing inter prediction based on the variable for scaling for the picture. The at least one offset is defined with a direction of scaling.
Abstract: Provided herein are bifunctional compounds with a moiety or domain that is a binder of the ubiquitin receptor RPN13 and another moiety or domain that is a binder of a target protein DOT1L to induce degradation of DOT1L. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers). Provided also are methods of inducing the degradation of DOT1L by administering a bifunctional compound or composition described herein, wherein one domain of the bifunctional compound is a binder of the ubiquitin receptor RPN13 and another domain of the compound is a binder of the target protein DOT1L in a subject.
Abstract: Described herein is a surge tank based system to control surge tanks in a manufacturing train. The system includes data acquisition unit, data normalization unit, deviation identification and handling unit and an real time execution of control action from centralized computer in a manufacturing process unit, wherein said manufacturing unit includes an integrated system which incorporates a plurality of pumps, surge tanks, and weighing balances, and other unit operations alongside the normal unit operations of production of output product.
Type:
Application
Filed:
August 6, 2021
Publication date:
February 17, 2022
Applicant:
INDIAN INSTITUTE OF TECHNOLOGY DELHI
Inventors:
ANURAG S. RATHORE, GARIMA THAKUR, NIKITA SAXENA, ANAMIKA TIWARI
Abstract: A virtual stage based on parallel simulation, includes a stage modeling unit, a motion simulation unit, a display simulation unit, and a data extraction output unit. The stage modeling unit performs stage simulation modeling according to the designed stage styling; the motion simulation unit simulates a stage motion in a simulation system according to the designed stage animation; the display simulation unit is configured to simulate LED screen display of the stage in the simulation system according to the designed stage background. The data extraction output unit includes a styling extraction output unit, a motion extraction output unit and a display extraction output unit, which are configured to extract data from the stage modeling unit, the motion simulation unit, and the display simulation unit respectively for processing and conversion, and output geometric styling parameters of an actual stage, stage mechanical motion parameters, and stage LED screen display parameters.
Abstract: Methods of making decellularized tendon matrix (DTM) and DTM hydrogels are provided. These compositions and hydrogels are useful for repairing tendon injuries and in some cases may be used by injection, arthroscopic procedures, or as adjuncts to traditional surgical repair.
Type:
Application
Filed:
December 20, 2019
Publication date:
February 17, 2022
Applicant:
The Steadman Clinic and Steadman Philippon Research Institute
Inventors:
Chelsea S. BAHNEY, Peter J. MILLETT, David BERNHOLT, Anna-Laura NELSON
Abstract: The present invention is directed to antibodies binding to MUC1-C/extracellular domain (MUC1-C/ECD) and methods of using such antibodies to treat cancers that express the MUC1 antigen.
Type:
Application
Filed:
October 5, 2021
Publication date:
February 17, 2022
Applicants:
DANA-FARBER CANCER INSTITUTE, INC., GENUS ONCOLOGY, LLC
Abstract: A three-dimensional porous composite electrode includes a three-dimensional porous current-collector and an active material layer including an active material and having a three-dimensional structure along a surface of the three-dimensional porous current-collector. The three-dimensional porous current-collector extends along a first direction, includes a current-collecting material and has a porosity gradient along a second direction perpendicular to the first direction. The three-dimensional porous composite electrode has a ratio gradient of the active material to the current-collecting material along the second direction.
Type:
Application
Filed:
February 17, 2021
Publication date:
February 17, 2022
Applicant:
Korea Advanced Institute of Science and Technology
Abstract: Communication systems and methods in accordance with various embodiments of the invention utilize modulation on zeros. Carrier frequency offsets (CFO) can result in an unknown rotation of all zeros of a received signal's z-transform. Therefore, a binary MOCZ scheme (BMOCZ) can be utilized in which the modulated binary data is encoded using a cycling register code (e.g. CPC or ACPC), enabling receivers to determine cyclic shifts in the BMOCZ symbol resulting from a CFO. Receivers in accordance with several embodiments of the invention include decoders capable of decoding information bits from received discrete-time baseband signals by: estimating a timing offset for the received signal; determining a plurality of zeros of a z-transform of the received symbol; identifying zeros from the plurality of zeros that encode received bits by correcting fractional rotations resulting from the CFO; and decoding information bits based upon the received bits using a cycling register code.
Type:
Application
Filed:
March 17, 2021
Publication date:
February 17, 2022
Applicants:
California Institute of Technology, The Regents of the University of California, Technische Universität Berlin
Inventors:
Philipp Walk, Babak Hassibi, Peter Jung, Hamid Jafarkhani
Abstract: The present disclosure provides a biomimetic cell culture apparatus that mimics interactions among organs in a human body. The present disclosure includes a plurality of culture units for culturing cells, a conduit for connecting the plurality of culture units to each other to form a circulating path, a pump unit disposed on the conduit for forming a flow in culture medium such that the culture medium circulates through the plurality of culture units, and an agitating module for agitating the plurality of culture units.
Type:
Application
Filed:
August 14, 2020
Publication date:
February 17, 2022
Applicant:
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
Inventors:
Cho Rok JUNG, Jung Hwa LIM, Hyun Mi KANG, Kyung Hee NOH, Kyung Sook CHUNG, Mi Young SON, Myung Jin SON
Abstract: The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells am molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described hemin are useful for treating retinal degenerative diseases.
Type:
Application
Filed:
March 29, 2021
Publication date:
February 17, 2022
Applicant:
Astellas Institute for Regenerative Medicine
Inventors:
Christopher Malcuit, Linda Lemieux, William Holmes, Pedro Huertas, Lucy Vilner