Patents Assigned to INSTITUTE
  • Publication number: 20220050064
    Abstract: A NEMS readout system includes a sensor array comprising a plurality of sensors. Each sensor of the plurality of sensors including a resonator with frequency characteristics different from the resonator of each other sensor of the plurality of sensors. A readout signal indicative of a plurality of output signals is collected from the sensor array. Each output signal of the plurality of output signals corresponding to one of the plurality of sensors. An analysis of the plurality of output signals is performed to identify a plurality of resonant frequencies and to detect a frequency shift associated with at least one of the plurality of resonant frequencies.
    Type: Application
    Filed: October 27, 2021
    Publication date: February 17, 2022
    Applicant: California Institute of Technology
    Inventors: Michael L. Roukes, Chung Wah Fon, Ewa Rej
  • Patent number: 11248309
    Abstract: Disclosed is a method of preparing single crystal ingot of barium zirconium oxide. The method includes preparing a cylindrical BaZrO3 ceramic by pulverizing a BaZrO3 compound into a powder and sintering the same into a cylindrical ceramic form, ii) fixing two cylindrical BaZrO3 ceramics to an optical floating zone furnace, joining the two cylindrical BaZrO3 ceramics together and melting the junction at a temperature of 2,600 to 3,500° C. using light emitted from a xenon lamp or laser, and after the melting, moving the two cylindrical BaZrO3 ceramics in a direction parallel to an axis of rotation thereof, enabling the molten junction to be solidified, and thereby growing a single crystal.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: February 15, 2022
    Assignee: UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventor: Yoon Seok Oh
  • Patent number: 11248624
    Abstract: A centrifugal compressor includes a volute base block, a volute cover plate, an impeller, a diffuser-adjusting assembly, a radial constraint assembly, an axial constraint assembly and a driving assembly. A diffuser and a connected volute are formed between the cover plate and the base block. The impeller discharges gas to the centrifugal compressor through the diffuser and the volute. The diffuser adjustment assembly includes a driving ring, a driving rod, a pin and a diffuser ring. The radial constraint assembly is disposed on an inner circumference surface of the driving ring. The axial constraint assembly on an outer circumference surface of the driving ring is located between the top and bottom portions. The drive assembly is to rotate the driving ring. When the driving ring rotates, the pin slides along the pin track, and the driving rod displaces the diffuser ring to adjust a flow-path width of the diffuser.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: February 15, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jun-Jie Lin, Jenn-Chyi Chung, Chung-Che Liu, Kuo-Shu Hung
  • Patent number: 11246711
    Abstract: An integral humeral stem includes a diaphyseal portion which has, orthogonal to a diaphyseal axis, an octagonal cross-section with convex rounded angles, and a metaphyseal portion in the form of a flared corolla which extends the diaphyseal portion up to a proximal face, which has, orthogonal to a central axis, an octagonal cross-section with convex rounded angles so that the humeral stem has a peripheral surface provided with eight lateral facets and eight rounded fillets which continuously extend from the diaphyseal portion to the metaphyseal portion. On the metaphyseal portion, the rounded fillets progressively widen and the lateral facets progressively narrow from the diaphyseal portion in the direction of the proximal face.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: February 15, 2022
    Assignee: SHOULDER FRIENDS INSTITUTE
    Inventors: Yves Lefebvre, Stephane Audebert, Johannes Barth, Christophe Charousset, Jerome Garret, David Gallinet, Jacques Guery, Thierry Joudet, Arnaud Godeneche
  • Patent number: 11248007
    Abstract: Provided herein are compounds that inhibit MALT1, a protein whose activity is responsible for constitutive NF-?B signaling in certain cancers (e.g., activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL)). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating MALT1-related diseases and disorders (e.g., cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: February 15, 2022
    Assignees: Cornell University, Dana-Farber Cancer Institute, Inc.
    Inventors: Nathanael S. Gray, David A. Scott, John Hatcher, Ari M. Melnick, Lorena Fontan Gabas
  • Patent number: 11251323
    Abstract: A system for providing a solar harvesting building envelope is disclosed. The system includes a plurality of solar harvesting apparatus configured to be installed as or on a building envelope in manner like that of traditional shingles or siding. The apparatus includes a frame having a photovoltaic end wall, as well as reflective base and side walls. A translucent, wedge-shaped body layer is positioned on the frame. A luminescent species film is positioned at and substantially parallel to a base of the wedge-shaped body layer, such that the luminescent species film is positioned at an angle relative to the photovoltaic end wall. Light incident on the wedge-shaped body layer is concentrated towards the photovoltaic end wall, such as through absorption and re-emission along with scattering by the luminescent species film and internal reflection by the wedge-shaped body layer and the reflective base and side walls of the frame.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: February 15, 2022
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Michael Hughes, Diana-Andra Borca-Tasciuc, Deborah A. Kaminski
  • Patent number: 11251653
    Abstract: Disclosed is a system for tracking a maximum power point. The system includes an energy harvesting device, a power management integrated circuit including a switching circuit that adjusts an input voltage that is transmitted from the energy harvesting device and a conversion circuit that converts the input voltage adjusted by the switching circuit to output an output voltage, and a measuring device that calculates a ratio of a second power based on the input voltage to a first power based on an open circuit voltage of the energy harvesting device, using an internal impedance of the energy harvesting device and an input impedance of the power management integrated circuit.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: February 15, 2022
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Jong Pil Im, Seungeon Moon, Jeong Hun Kim, Jiyong Woo, Yeriaron Kim, Solyee Im
  • Patent number: 11246873
    Abstract: The present invention provides methods of inducing differentiation of oligodendrocyte progenitor cells to a mature myelinating cell fate with a neurotransmitter receptor modulating agent. The present invention also provides methods of stimulating increased myelination in a subject in need thereof by administering said neurotransmitter receptor modulating agent. Methods of treating a subject having a demyelinating disease using a neurotransmitter receptor modulating agent are also provided.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: February 15, 2022
    Assignee: The Scripps Research Institute
    Inventors: Peter Schultz, Luke Lairson, Vishal Deshmukh, Costas Lyssiotis
  • Patent number: 11248304
    Abstract: A method for producing a transparent electrode for oxygen production having a Ta nitride layer on a transparent substrate, including: a step of forming a Ta nitride precursor layer on the transparent substrate; and a step of nitriding the Ta nitride precursor layer with a mixed gas containing ammonia and a carrier gas.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: February 15, 2022
    Assignees: Mitsubishi Chemical Corporation, THE UNIVERSITY OF TOKYO, JAPAN TECHNOLOGICAL RESEARCH ASSOCIATION OF ARTIFICIAL PHOTOSYNTHETIC CHEMICAL PROCESS, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Hiroshi Nishiyama, Tomohiro Higashi, Yutaka Sasaki, Taro Yamada, Kazunari Domen, Yohichi Suzuki, Seiji Akiyama
  • Patent number: 11248709
    Abstract: A fast blind plate switching device, comprising a sealing structure, a clamping structure, a support structure and an execution mechanism. The blind plate has an open-state structure and a blind-state structure. The support structure is used for connecting pipelines at two sides and providing support for the whole device. The clamping structure and the sealing structure are located inside the support structure. The clamping structure is driven by the execution mechanism, and under the drive of the execution mechanism, the clamping structure presses on the blind plate (1) to eliminate a gap between two sides of the blind plate, so that a seal is formed by means of the sealing structure. When a gap is formed away from the blind plate (1), the open/blind state of the blind plate (1) is switched.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: February 15, 2022
    Assignees: BEIJING AEROSPACE PROPULSION INSTITUTE, BEIJING AEROSPACE PETROCHEMICAL TECHNOLOGY & EQUIPMENT ENGINEERING CORPORATION LIMITED
    Inventors: Yang Gao, Shuai Wu, Lei Liu, Limin Dai, Xuebin Wang, Xiangyu Chen, Shuai Li
  • Patent number: 11247991
    Abstract: The present application provides bifunctional compounds of Formula (Ia) or (Ib): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which act as protein degradation inducing moieties for cyclin-dependent kinase 8 (CDK8). The present application also relates to methods for the targeted degradation of CDK8 through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to CDK8 which can be utilized in the treatment of disorders modulated by CDK8.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: February 15, 2022
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael S. Gray, Tinghu Zhang, Calla M. Olson, Yanke Liang, Nicholas Kwiatkowski
  • Patent number: 11249150
    Abstract: Exemplary embodiments of the present disclosure provide a spin valve and a spintronic device comprising the same. The spin valves may comprise two or more magnetic layers stacked in sequence, wherein any two adjacent magnetic layers among the two or more magnetic layers have different coercive forces, and at least one of the any two adjacent magnetic layers is a van der Waals magnetic layer, wherein the van der Waals magnetic layer refers to a magnetic layer made of a van der Waals magnetic material.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: February 15, 2022
    Assignee: Institute of Semiconductors, Chinese Academy of Sciences
    Inventors: Kaiyou Wang, Ce Hu
  • Patent number: 11251438
    Abstract: A structure, and more specifically a tube-shaped structure having an inner surface and two ends, wherein one or both ends are open and the inner surface is exposed through said one or both open ends, and a metal provide on the inner surface. Also, an electrode active material, such as lithium metal, on the metal included on the inner surface of the tube.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: February 15, 2022
    Assignees: LG ENERGY SOLUTION, LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Eunkyung Park, Jang Wook Choi, Byung Gon Kim, Minchul Jang, Byoungkuk Son, Junghun Choi, Donghyeon Kang
  • Patent number: 11251609
    Abstract: A surge protection apparatus includes a signal determination unit configured to generate a control signal by detecting a surge on a power line, and a switching unit connected between the power line and a ground terminal and configured to include a power transistor that is turned on in response to the control signal.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: February 15, 2022
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Kwanguk Chu, Jinha Yoo, Namwon Moon, Seung-Kab Ryu
  • Patent number: 11248842
    Abstract: The present invention relates to the technical field of bee product processing, and discloses a continuous drying apparatus for bee pollen and related drying method. The continuous drying apparatus for bee pollen comprises: a box body; a first drying conveying structure; a second drying conveying structure; and a heat pump dehumidification heating structure. The continuous drying apparatus for bee pollen has the advantage of high drying efficiency.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: February 15, 2022
    Assignee: INSTITUTE OF APICULTURAL RESEARCH CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Wenjun Peng, Xiaoming Fang, Liming Wu, Wenli Tian, Lingyu Gao, Yazhou Zhao, Yuemin Tong, Hongwei Xiao, Shengming Han
  • Patent number: 11252408
    Abstract: An image processing apparatus includes a storage unit, a selection unit, and an encoding unit. The storage unit stores pre-synchronized image data. The selection unit selects as a reference image at least one of the pre-synchronized image data based on a result of comparison between the pre-synchronized image data and an original image data. The encoding unit generates a compressed image data by compressing the original image data using the reference image. The selection unit calculates similarity between the original image data and at least one of the pre-synchronized image data and selects the reference image among the synchronized image data based on the calculated similarity.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: February 15, 2022
    Assignee: Ulsan National Institute of Science and Technology
    Inventors: Kyunghan Lee, Wooseung Nam
  • Patent number: 11246822
    Abstract: A method for skin care and/or maintenance including applying or administering a preparation to a subject is provided. The preparation includes a biomedical composition, and the biomedical composition includes an effective amount of micelle, wherein the micelle includes a hyaluronic acid and/or a derivative thereof and a modified histidine. The modified histidine is grafted to at least one primary hydroxyl group of the hyaluronic acid and/or the derivative thereof, and a graft ratio of the modified histidine is 1-100%. Moreover, the hyaluronic acid and/or the derivative thereof and the modified histidine form the micelle on a weight percentage of 0.2-300:1.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: February 15, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Ting-Yu Shih, Lu-Chih Wang, Yuan-Kun Yu, Yi-Ting Hsieh, Yu-Chun Liu, Jing-Wen Tang
  • Patent number: 11248033
    Abstract: A nucleic acid sequence is provided that encodes a chimeric protein comprising a ligand that comprises a naturally occurring or modified follicle stimulating hormone sequence, e.g., an FSH? sequence, or fragment thereof, which ligand binds to human follicle stimulating hormone (FSH) receptor, linked to either (a) a nucleic acid sequence that encodes an extracellular hinge domain, a transmembrane domain, a co-stimulatory signaling region, and a signaling endodomain; or (b) a nucleic acid sequence that encodes a ligand that binds to NKG2D. The vector containing the nucleic acid sequence, the chimeric proteins so encoded, and modified T cells expressing the chimeric protein, as well as method of using these compositions for the treatment of FSHR-expressing cancers or tumor cells are also provided.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: February 15, 2022
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Alfredo Perales-Puchalt, Jose R. Conejo-Garcia
  • Patent number: 11248261
    Abstract: The present invention relates to the identification of a novel allele of the RHD gene associated with a weak D phenotype and the kits and methods for detecting this allele.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: February 15, 2022
    Assignees: ETABLISSEMENT FRANCAIS DU SANG, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), NATIONAL INSTITUTE OF IMMUNOHAEMATOLOGY, UNIVERSITE DE BRETAGNE OCCIDENTALE (UBO)
    Inventors: Yann Fichou, Swati Kulkarni
  • Patent number: 11250600
    Abstract: A method for processing an X-ray computed tomography (CT) image using a neural network and an apparatus therefor are provided. An image reconstruction method includes receiving low-dose X-ray CT data, obtaining an initial reconstruction image for the received low-dose X-ray CT data using a predetermined analytic algorithm, and reconstructing a denoised final image using the obtained initial reconstruction image and a previously trained neural network.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: February 15, 2022
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jong Chul Ye, Eun Hee Kang