Patents Assigned to INSTITUTE
  • Patent number: 11254790
    Abstract: The present invention discloses a silicone rubber and a method for preparing it, and a phenolic modified silicone rubber resin and a method for preparing it. The structural formula of the silicone rubber is shown as follows: Wherein x=70-80, y=10-20. The structural formula of the phenolic-modified silicone rubber resin is shown as follows: wherein n, x, y are degrees of polymerization, n=10-20, x=70-80, y=10-20. A method for preparing the phenolic-modified silicone rubber resin orderly comprises: adding 90-110 parts by mass of brominated phenolic resin and 180-220 parts of organic solvent into 100 parts by mass of silicone rubber, reacting at 70-80° C. for 24-48 h until the solution is clear and transparent; adding 9-11 parts by mass of capping agent, reacting for another 4-5 h to obtain a reaction liquid containing phenolic-modified silicone rubber resin.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: February 22, 2022
    Assignee: AEROSPACE RESEARCH INSTITUTE OF MATERIALS & PROCESSING TECHNOLOGY
    Inventors: Chen He, Wu Lu, Boqian Li, Yibing Zeng, Junshan Wang
  • Patent number: 11254156
    Abstract: An approach to printing a nickel precursor ink on a wide range of substrates for electronics and magnetic applications is disclosed. The nickel ink reduces to elemental nickel following heating. The ink was printed using an ultrasonic aerosol printing technique. By sintering the nickel precursor ink in the presence of a homogeneous magnetic field, the reduced nickel complex formed continuously aligned nickel nanofibers axially aligned with the direction of the magnetic field. The fabrication of aligned interlayered nanofiber films provides opportunities to produce structures with enhanced isotropic electrical and magnetic properties. The resistivity of the film was found to be as low as 0.56 m?·cm, and the saturation magnetization was measured to be 30 emu/g, which is comparable to bulk Ni. Magnetic anisotropy was induced with an easy axis along the direction of the applied magnetic field with soft magnetic properties.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: February 22, 2022
    Assignee: Rochester Institute of Technology
    Inventors: Chaitanya G. Mahajan, Denis Cormier, Mark Irving, Scott Williams, David Borkholder, Ahmed Alfadhel
  • Patent number: 11253727
    Abstract: Magnetic resonance (“MR”) visible markers for use in MR-guided placement of brachytherapy seeds, and for use in other MR-guided interventional procedures, are described. The MR-visible markers generally include a tube in which an absorbent thread assembly is disposed. The tube is made fluid-tight by sealing it at both ends with suitable end plugs. The absorbent thread assembly is soaked in a suitable MR-visible fluid.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: February 22, 2022
    Assignee: Sunnybrook Research Institute
    Inventors: Ananth Ravi, Moti Raj Paudel, Amir Owrangi, Harry Easton
  • Patent number: 11254866
    Abstract: Provided is a fluoride nanophosphor using, as cores, luminescent nanoparticles expressed by Chemical Formula 1. LiEr1-x-yLyF4:Tm3+x??[Chemical Formula 1] (In Chemical Formula 1, x is a real number satisfying 0?x?0.3, y is a real number satisfying 0?y?0.8 and is selected within a range satisfying 0?x+y?0.9, and L is any one selected from the group consisting of yttrium (Y), lanthanum (La), cerium (Ce), praseodymium (Pr), neodymium (Nd), promethium (Pm), samarium (Sm), europium (Eu), gadolinium (Gd), terbium (Tb), dysprosium (Dy), holmium (Ho), ytterbium (Yb), lutetium (Lu), and a combination thereof.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: February 22, 2022
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ho Seong Jang, A Ra Hong, So Hye Cho, Seung Yong Lee
  • Patent number: 11253516
    Abstract: The present invention relates to a N2,N4-diphenylpyrimidin-2,4-diamine derivative, a method for preparing the same, and a pharmaceutical composition for the prevention or treatment of cancer, containing the same as an active ingredient. The derivative shows a relatively weak EGFR activity inhibitory effect on wild-type EGFR, a high inhibitory ability on EGFR mutation, and a high inhibitory ability on even FLT3 and FLT3 mutation, and thus, can be effectively used for the treatment of cancer with EGFR mutation or cancer with FLT3 or a mutation thereof, and the derivative shows a synergy effect at the time of combination administration, and thus can be effectively used for the treatment of combination administration.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: February 22, 2022
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Kwangho Lee, Inji Shin, Gildon Choi, Chong Hak Chae, Hyeon Jeong Choe, Myoung Eun Jung, Byeong Uk Jeon, Byoung Chul Cho, Chae Won Park, Hwan Kim, Krishna Babu Duggirala
  • Patent number: 11255868
    Abstract: Provided is fluid control equipment for bio-reaction, including a pipette configured to transport a reaction solution, and a liquid pump configured to adjust the internal pressure of the pipette.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: February 22, 2022
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Kwang Hyo Chung, Bong Kyu Kim, Jin Tae Kim, Chang-Geun Ahn, Eun-Ju Jeong, Chul Huh
  • Patent number: 11255025
    Abstract: The present invention relates to a spinning nozzle apparatus for manufacturing a high-strength fiber. The spinning nozzle apparatus for manufacturing a high-strength fiber according to the present invention is designed to optimize a heating method for the spinning region of a spinning nozzle in the melt spinning process. The heat transfer method is optimized by disposing the spinning nozzle holes of spinning nozzle commercially available on the outside of, directly under the pack body and heating the spinning nozzle holes with a heating body. In addition, an instantaneous heat treatment at high temperature is adopted to control the molecular entanglement structure in the melted polymer, which enhances the drawability of the thermoplastic resin and hence improves the mechanical properties such as strength and elongation.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: February 22, 2022
    Assignee: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY
    Inventors: Wan Gyu Hahm, In Woo Nam, Seung Jin Lee, Ki Sub Lim
  • Patent number: 11254343
    Abstract: A vehicle system including one or more sensors, a steering wheel including a rim and an adjusting mechanism for adjusting a coefficient of friction between a surface of the rim and a driver's hand, and a controller configured to determine whether a deviation factor between a target path and an actual path based on the one or more sensors exceeds a threshold deviation, send a first signal to the adjusting mechanism for operating to a first state in response to determining that the deviation factor exceeds the threshold deviation, the coefficient of friction being decreased when the adjusting mechanism is in the first state, and send a second signal to the adjusting mechanism for operating to a second state in response to determining that the deviation factor does not exceed the threshold deviation, the coefficient of friction being increased when the adjusting mechanism is in the second state.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: February 22, 2022
    Assignee: TOYOTA RESEARCH INSTITUTE, INC.
    Inventors: Manuel Ludwig Kuehner, Jaime Camhi
  • Patent number: 11254908
    Abstract: This application relates to methods and materials for providing a benefit to a seed, seedling or plant by producing seeds that are internally colonized with endophytes. Beneficial endophytes with particular characteristics are provided. These may be used in the methods described to provide a benefit to a seed, seedling or plant.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: February 22, 2022
    Assignees: Indigo Ag, Inc., AIT Austrian Institute of Technology GMBH
    Inventors: Birgit Mitter, Muhammad Naveed, Teresa Berninger, Stephane Compant, Angela Sessitsch, Geoffrey Von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Jonathan W. Leff, Phillip Samayoa, Craig Sadowski
  • Patent number: 11254934
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 600 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in retinal endothelial cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: February 22, 2022
    Assignee: FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Josephine Juettner, Botond Roska
  • Patent number: 11253155
    Abstract: A brain activity estimation device includes a brain activity estimation portion. The brain activity estimation portion includes a blood-circulation-amount calculating unit and an estimation unit. The blood-circulation-amount calculating unit is configured to calculate time-series blood-circulation-amount data on a facial surface of a human based on RGB data of photographed image data on the facial surface acquired in time series. The RGB data is obtained by conducting RGB processing on the photographed image data. The RGB processing includes decomposing the photographed image data into three color components composed of an R component, a G component and a B component. The estimation unit is configured to estimate brain activity of the human based on a plurality of decomposition components obtained by decomposing the blood-circulation-amount data by singular value decomposition, principal component analysis, or independent component analysis.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: February 22, 2022
    Assignees: Daikin Industries, Ltd., TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Junichiro Arai, Yasunori Kotani, Yoshimi Ohgami, Taro Tomatsu
  • Patent number: 11254043
    Abstract: The present invention aims at providing a high-accuracy contactless measurement method for measuring the temperature of a metal thermoforming mold, which is capable of timely monitoring the metal temperature in multiple areas and also has threshold warning functionalities for delivering real-time notifications, in order to save the labor costs for long-term monitoring.
    Type: Grant
    Filed: December 23, 2018
    Date of Patent: February 22, 2022
    Assignee: National Chung-Shan Institute of Science and Technology
    Inventors: Shiang-Feng Tang, Shun-Lung Yen, Kun-Chi Lo, Wen-Jen Lin
  • Patent number: 11255220
    Abstract: Heat exchanger assemblies and methods for providing heat exchange as well as methods providing specific energy to predetermined materials within an assembly as well as gas turbine engines as well as methods of powering same are provided. Heating assemblies are provided that can include: a heat-sinking substrate; and a selective emitter layer in thermal communication with the substrate. These assemblies can be provided as part of heat exchanger assemblies. Methods for providing heat to a fluid are also provided that can include heating a layer upon a substrate to provide photons of a predetermined wavelength to a fluid from the layer. Turbine combustion engines are also provided that can include a turbine having at least a portion of the blades in the hot section of the turbine coated with an emissivity layer in thermal communication with the turbine blade. Methods for powering turbine combustion engines are also provided.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: February 22, 2022
    Assignee: Battelle Memorial Institute
    Inventors: B. Peter McGrail, Jeromy J. Jenks, Bruce E. Bernacki
  • Patent number: 11253521
    Abstract: Described inter alia are compounds according to formula (I): or a pharmaceutically acceptable salt thereof, and uses in methods for the modulation of flap endonuclease 1 (FEN1), Xeroderma Pigmentosum Complementation Group G protein (XPG), Exonuclease 1 (EXO1) and/or GEN1.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: February 22, 2022
    Assignee: Ludwig Institute for Cancer Research Ltd
    Inventors: Timothy Gahman, Andrew Shiau, Richard Kolodner
  • Patent number: 11258968
    Abstract: Examples of image sensors are described herein. In an example, an image sensor may comprise an array of hybrid pixels, where each hybrid pixel includes light sensing unit and a non-volatile memory component coupled to the light sensing unit. The light sensing unit comprises a light detecting element and a charge to voltage conversion unit. The charge to voltage conversion unit is to provide an output pixel signal (VPD), based on photo-electrons generated by the light detecting element. Further, the non-volatile component when calibrated to an initial resistance state is to compress the output pixel signal (VPD) during exposure.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: February 22, 2022
    Assignee: Indian Institute of Technology Delhi
    Inventors: Manan Suri, Mukul Sarkar
  • Patent number: 11256373
    Abstract: An input sensing unit that utilizes conductive layers to sense various types of input. The input sensing unit may include a first conductive layer including first sensing electrodes; a second conductive layer disposed on the first conductive layer, the second conductive layer including second sensing electrodes and third sensing electrodes; and at least one insulating layer insulating the first conductive layer and the second conductive layer from each other. The input sensing unit senses at least one of a touch, a pressure, and a degree of moisture based on a change in capacitance between the conductive layers.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: February 22, 2022
    Assignees: SAMSUNG DISPLAY CO., LTD., UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventors: Jae Ik Lim, Won Sang Park, Hye Yong Chu, Kibog Park, Sungchul Jung, Hanbyul Jin
  • Patent number: 11255656
    Abstract: Our high phase sensitivity wide-field phase cancellation interferometry system allows single-shot, label-free optical sensing of neural action potentials via imaging of optical path length changes. Single-shot sensing and monitoring of single neurons within a neural network should lead to a more comprehensive understanding neural network processing, which is beneficial for the advancement in the field of neuroscience as well as its biomedical applications and impact. Our system cancels the phase profile of the resting neuron from the phase profile of the spiking neuron, improving the sensitivity by two orders of magnitude. Using a detector with an extremely large well depth and an appropriately biased interferometer increases the sensitivity by another order of magnitude, yielding a measurement that is three orders of magnitude more sensitive than those possible with other microscopes.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: February 22, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Peter T. C. So, Zahid Yaqoob, Dominika Lyzwa, Vijay Singh, Dushan N. Wadduwage
  • Patent number: 11253367
    Abstract: There is provided a scaffold for bone regeneration which is adapted to be implanted at a bone defect site of a bone. The scaffold comprises a main support member configured to be fixed to the bone, and a load supporting unit configured to be installed in the bone defect site of the bone to selectively bear a load applied to the bone. The load supporting unit includes one or two supporting pieces to be installed in the bone defect site of the bone to selectively bear a load applied to the bone. The supporting piece has at one end portion a contact portion to be brought into contact with and fixed to a compact bone in the bone defect site of the bone. The other end portion of the supporting piece is selectively coupled to the main support member.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: February 22, 2022
    Assignee: Institute for Advanced Engineering
    Inventors: Kyoung-Don Lee, Tae-Suk Suh, Jong Won Rhie, Ki-Young Park, Jae-Sung Kim, Byeong-Ju Jin, Ki Joo Kim, Do-kun Yoon
  • Patent number: 11254682
    Abstract: The present disclosure provides novel heteroaryl compounds of formula (IV). Such compounds are useful for the treatment of cancers.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: February 22, 2022
    Assignees: THE SCRIPPS RESEARCH INSTITUTE, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael S. Gray, Jianming Zhang, Barun Okram, Xianming Deng, Jae Won Chang, Amy Wojciechowski
  • Patent number: 11254566
    Abstract: A preparation method of a bionic adhesive material with a tip-expanded microstructural array includes the following steps: machining through-holes on a metal sheet; modifying morphology of a through-hole by electroplating, using the metal sheet in step 1 as an electroplating cathode, and arranging the electroplating cathode and an electroplating anode in parallel to prepare a hyperboloid-like through-hole array assembly, fitting a lower surface of the hyperboloid-like through-hole array assembly tightly to an upper surface of a substrate assembly to prepare a through-hole assembly of a mold; and filling the mold assembly with a polymer, curing, and demolding to obtain the adhesive material with the tip-expanded microstructural array.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: February 22, 2022
    Assignees: NANJING UNIVERSITY OF AERONAUTICS AND ASTRONAUTICS, NANJING LI-HANG INDUSTRY INSTITUTE OF BIONIC TECHNOLOGY LIMITED COMPANY
    Inventors: Zhendong Dai, Keju Ji, Enhua Cui, Jian Chen, Cong Yuan, Yiqiang Tang