Abstract: The present invention relates to methods for shifting the splicing profile of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding U7-based small nuclear RNAs to induce DUX4 exon-skipping and the expression of shortened forms of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.

Abstract: In an aspect, provided herein are methods for producing sulfuric acid and hydrogen gas, the methods comprising steps of: providing sulfur dioxide formed by thermal conversion of a sulfur-containing species; electrochemically oxidizing said sulfur dioxide to sulfuric acid in the presence of water; and electrochemically forming hydrogen gas via a reduction reaction. In some embodiments, the methods comprise a step of thermally converting said sulfur-containing species to said sulfur dioxide. Systems configured to perform these methods are also disclosed herein. Also provided herein are methods and systems for producing sulfuric acid and hydrogen gas by electrochemically forming the sulfuric acid and the hydrogen gas in a mixture comprising a sulfur material, a supporting acid, and water. Also provided herein are methods and systems for producing a cement material.

Abstract: Disclosed are an additive raw material composition and an additive for superhard material product, a composite binding agent, a superhard material product, a self-sharpening diamond grinding wheel and a method for manufacturing the same. The raw material composition consisting of components in following mass percentage: Bi2O3 25%˜40%, B2O3 25%˜40%, ZnO 5%˜25%, SiO2 2%˜10%, Al2O3 2%˜10%, Na2CO3 1%˜5%, Li2CO3 1%˜5%, MgCO3 0%˜5%, and CaF2 1%˜5%. The composite binding agent is prepared from the additive and a metal composite binding agent. The self-sharpening diamond grinding wheel prepared from the composite binding agent has high self-sharpness, high strength, and fine texture, is uniformly consumed during the grinding process, does not need to be trimmed during the process of being used, and maintains good grinding force all the time, fundamentally solving the problems of long trimming time and high trimming cost of the diamond grinding wheel (FIG. 1).

Abstract: A time-of-flight imaging system may output light with a modulation frequency in the gigahertz band, to illuminate a range target. This high-frequency illumination may enable extremely precise—e.g., micron-scale—depth measurements. The system may modulate reflected light from the range target, to create a beat tone that has a frequency in the hertz band. In some cases, the modulated light in the gigahertz band is created by a first modulator and the beat tone in the hertz band is created by a second modulator. In some cases, the modulated light in the gigahertz band is created by an upshift cascade of modulators and the beat tone in the hertz band is created by a downshift cascade of modulators. A photodetector may measure the low-frequency beat tone. From this beat tone, phase of the signal and depth of the range target may be extracted.

Abstract: A method of processing a transmission signal may comprise grouping a coded bit sequence including a plurality of coded bits into a plurality of groups; comparing indices of code bits belonging to a first group among the plurality of groups and indices of code bits belonging to a second group among the plurality of groups; configuring the coded bits belonging to the first group as higher bits among bits constituting each modulation symbol based on a result of comparing the indices of the coded bits; configuring the coded bits belonging to the second group as lower bits among the bits constituting each modulation symbol based on the result of comparing the indices of the code bits; and generating the each modulation symbol by using the higher bits and the lower bits.

Abstract: A method and an apparatus for allocating a flexible transmission slot in a wireless local area network (LAN) system are disclosed. A flexible transmission slot allocation method of an access point (AP) in a wireless local area network (WLAN) system according to an exemplary embodiment includes transmitting a beacon including a traffic indication map (TIM) bit to a station, receiving a power save poll (PS-Poll) from the station in a slot implicitly allocated by the TIM bit, and transmitting an acknowledgement (ACK) including transmission slot allocation information on downlink data to the station.

Abstract: The present invention relates to a method for preparing a sulfated metal oxide catalyst for chlorination, and a method for producing a reaction product containing methyl chloride (CH3Cl) by using the sulfated metal oxide catalyst. A sulfated zirconia catalyst and a sulfated tin oxide catalyst are disclosed as the sulfated metal oxide catalyst for chlorination.

Abstract: The present disclosure provides compositions and therapies that can address both the symptoms and disorders associated with insufficient surfactant production and hyperoxia. In one embodiment, the composition can be formulated for aerosol delivery during ventilation therapy. The composition can comprise one or more of the following: a PPAR gamma agonist, a surfactant peptide, and one or more phospholipids. The compositions are formulated to provide the complementary benefits of reducing the likelihood of developing or the severity of RDS in infants, as well as protecting and promoting lung maturation in a hyperoxic environment.

Abstract: A high-throughput communications channel is encoded using transmit waveforms which satisfy a variety of technical constraints deemed desirable for effective radar operations and signal processing. This enables new cooperative spectrum sharing modalities for radar and communications systems.

Abstract: A device and a method for preparing pure titanium by electrolysis-chlorination-electrolysis, wherein the device includes a first electrolytic cell, a second electrolytic cell, a chlorination reactor and guide tubes. The Cl2 generated at the anode of the first electrolytic cell is introduced into a chlorination reactor containing the TiCxOy or TiCxOyNz raw materials via a guide tube, and a chlorination is carried out to generate TiCl4 gas at a temperature of 200° C.-600° C. The TiCl4 gas passes through a guide tube into a cathode of the second electrolytic cell, and then an electrolysis is performed to obtain the high-purity titanium in the second electrolytic cell. At the same time, the Cl2 generated at the anode of the second electrolytic cell is recycled into the chlorination reactor in the first electrolytic cell to continue to participate in the chlorination of TiCxOy or TiCxOyNz.

Abstract: The present invention provides a reflective wide-angle lens having a large aperture (for example, FNO 1.7) and a small projection ratio (for example, TR?0.2). The reflective wide-angle lens reduces lens size and reduces the number of lenses required while achieving a clear focus on a wide range of screen sizes. The reflective wide-angle lens comprises a front lens group and a rear lens group. The front lens group comprises a first lens group and two second lens group. The rear lens group comprises a curved mirror. The first lens group comprises at least a triple cemented lens, an aspherical lens, and two spherical lenses. The second lens group comprises at least two aspherical lenses and two spherical lenses. The curved mirror is a concave optical symmetric aspheric mirror.

Abstract: A turbulent fluidized bed reactor, device and method for preparing para-xylene and co-producing light olefins from methanol and/or dimethyl ether and toluene, resolving or improving the competition problem between an MTO reaction and an alkylation reaction during the process of producing para-xylene and co-producing light olefins from methanol and/or dimethyl ether and toluene, and achieving a synergistic effect between the MTO reaction and the alkylation reaction. By controlling the mass transfer and reaction, competition between the MTO reaction and the alkylation reaction is coordinated and optimized to facilitate a synergistic effect of the two reactions, so that the conversion rate of toluene, the yield of para-xylene, and the selectivity of light olefins are increased. The turbulent fluidized bed reactor includes a first reactor feed distributor and a number of second reactor feed distributors and are arranged sequentially along the gas flow direction.

Abstract: A photonic aerosol particle sensor includes a plurality of photonic waveguide resonators each having a photonic waveguide disposed along a separate waveguide resonator path and each photonic waveguide having a lateral waveguide width different than the waveguide width of other photonic waveguide resonators in the plurality. All waveguides in the plurality of photonic waveguide resonators have a common vertical thickness and are formed of a common photonic waveguide material. An optical input connection couples light into the waveguide resonators. A particle input conveys aerosol particles toward the waveguide resonators and an aerosol particle output conveys aerosol particles away from the waveguide resonators. At least one optical output connection is optically connected to accept light out of the plurality of photonic waveguide resonators to provide a signal indicative of at least one characteristic of the aerosol particles to be analyzed.

Abstract: Systems, devices, and methods for manufacturing nanobubbles are disclosed herein. In an embodiment, a nanobubble generator system includes a medium, wherein in the medium is a liquid medium or a semi-liquid medium. A device is immersed in the medium. The device includes a ceramic membrane having a first surface and an opposing second surface, and pores extending through the membrane from the first surface to the second surface, and a hydrophobic porous coating layer disposed on the first surface of the membrane. The system includes a gas source for providing a gas to the medium. In operation, the gas enters pores on the second surface of the membrane and exits the coating layer in the form of nanobubbles.

Abstract: A system for recognizing collision positions of a plurality of moving objects in a screen includes an infrared camera configured to obtain an image frame when a plurality of moving objects move toward a screen, a memory configured to store a program for calculating a collision position in the screen on the basis of the image frame, and a processor configured to execute the program stored in the memory. By executing the program, the processor detects all of the plurality of moving objects from the image frame to generate a graph where moving objects included in a successive image frame are connected to one another, and calculates a collision position of the moving object included in the image frame and a collision position of the moving object in the screen on the basis of the graph.

Abstract: The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.

Abstract: The present invention relates to a method of preparing a hierarchically porous polymer and a hierarchically porous polymer prepared thereby. The method comprises the steps of: (a) polymerizing an external oil phase of a high internal phase emulsion (HIPE) consisting aqueous droplets to produce a cross-linked block copolymer; (b) obtaining a macroporous polymer with interconnected macropores by removing the aqueous droplets; and (c) treating the obtained porous polymer with a base, thereby obtaining a hierarchically porous polymer having three-dimensional mesopores formed in the macroporous walls. According to the method, the macropore size and mesopore size of the hierarchically porous polymer can all be controlled. The hierarchically porous polymer prepared by the method can easily separate polymers having different sizes, and thus is highly useful in the polymer separation field.

Abstract: The present invention relates to a glucose measurement device which is arranged and operates under the skin of a subject. One embodiment can comprise: a transmitting unit for wirelessly receiving power and transmitting measured biometric-related parameters; a clock recovery unit for recovering a frequency used for the wireless power reception of the communication unit; a direct frequency synthesizer for converting the recovered frequency recovered by the clock recovery unit into a first band frequency; a clock control unit, which divides the recovered frequency so as to input same in an injection locked oscillator as a specific interval frequency; the injection locked oscillator, which receives the first band frequency and the specific interval frequency so as to output a second band frequency; and a measurement unit for measuring subcutaneous biometric-related parameters by using the second band frequency.

Abstract: An immunogenic composition comprising of Diphtheria toxoid antigen (D), tetanus toxoid (T) antigen, Hepatitis B surface antigen (HBsAg), inactivated whole-cell B. pertussis (wP) antigen, Haemophilus influenzae type B (Hib) capsular saccharide conjugated to a carrier protein, Inactivated Polio Virus (IPV) antigen and additionally one or more antigens and the method of preparing the same. A fully liquid combination vaccine, showing improved immunogenicity, reduced reactogenicity and improved stability. Improved methods of formaldehyde inactivation, improved adsorption profile of Diphtheria toxoid antigen (D), tetanus toxoid (T) antigen and Hepatitis B (HepB) surface antigen adsorbed individually onto aluminium phosphate adjuvant, minimum total aluminum content (Al3+) and optimized concentration of 2-phenoxyethanol (2-PE) as preservative.

Abstract: Provided is a driving guide system, and more specifically, a system for guiding a vehicle occupant in driving through linguistic description. One embodiment of the present invention is an apparatus for guiding driving with linguistic description of a destination, which is installed on a vehicle and guides driving by outputting a linguistic description of a destination building, wherein the apparatus sets a destination according to a command or input, receives appearance information of a building of the destination from a server, and represents and outputs the appearance information in a linguistic form.