Abstract: The disclosure provides a method for passivating a silicon carbide epitaxial layer, relating to the technical field of semiconductors. The method includes the following steps: introducing a carbon source and a silicon source into a reaction chamber, and growing a silicon carbide epitaxial layer on a substrate; and turning off the carbon source, introducing a nitrogen source and a silicon source into the reaction chamber, and growing a silicon nitride thin film on an upper surface of the silicon carbide epitaxial layer. The silicon nitride thin film grown by the method has few defects and high quality, and may be used as a lower dielectric layer of a gate electrode in a field effect transistor. It does not additionally need an oxidation process to form a SiO2 dielectric layer, thereby reducing device fabrication procedures.

Abstract: A supercapacitor-like device is described that uses a porous, conductive foam as the electrodes. After the device is charged, an explosive wave front can be used to remove electrolyte from the metal foam. This creates a large net charge on each electrode, which will readily flow through a load placed across the electrodes. The removal of charge can potentially occur on a time scale of microseconds, allowing a supercapacitor to be used in pulsed power applications. The creation of this net charge requires significant energy, meaning this concept may also be suitable for removing kinetic energy from objects.

Abstract: Provided herein are methods and apparatus for characterizing high aspect ratio (HAR) structures of fabricated or partially fabricated semiconductor devices. The methods involve using small angle X-ray scattering (SAXS) to determine average parameters of an array of HAR structures. In some implementations, SAXS is used to analyze symmetry of HAR structures in a sample and may be referred to as tilted structural symmetry analysis-SAXS (TSSA-SAXS) or TSSA. Analysis of parameters such as tilt, sidewall angle, bowing, and the presence of multiple tilts in HAR structures may be performed.

Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject).

Abstract: A method for producing a recombinant adeno-associated virus (rAAV) and a recombinant baculovirus virus, the method including: (1) infecting an insect host packaging cell line with a corresponding recombinant baculovirus integrated with an rAAV genome ITR-GOI (gene of interest flanked by AAV inverted terminal repeats) and an AAV Cap gene or AAV Rep gene; (2) culturing the host packaging cell line infected with the recombinant baculovirus, so as to produce the recombinant adeno-associated virus; and (3) separating and purifying the recombinant adeno-associated virus obtained in (2).

Abstract: Provided are a flexible electronic device including device units, a first etching preventing layer provided on the device units, a conductive line provided on the first etching preventing layer and electrically connected to the device units, a flexible substrate covering the conductive line on the first etching preventing layer and the conductive line, a trench separating the device units and exposing a portion of a bottom surface of the first etching preventing layer and a side surface of each of the device units, and a flexible protective layer conformally covering a bottom surface of each of the device units and an inside of the trench, wherein each of the device units includes a protective substrate, driving parts provided on the protective substrate, and a first encapsulation layer configured to cover the driving parts, and a manufacturing method thereof.

Abstract: A method and apparatus for improving data quality using GNSS. The method is implemented through middleware for existing GNSS survey systems. The method and device automatically analyze streams of GNSS messages from a GNSS receiver mounted to a GNSS survey pole for preconfigured conditions and also automatically measure an angle or tilt of the GNSS survey pole. The middleware automatically locks onto a location point reading of the GNSS receiver when the GNSS survey pole is positioned in an acceptable vertical position, and any preconfigured conditions within the stream of GNSS messages are met. The middleware automatically repeats the GNSS message of the location point instead of the continuing live stream of data to enable a GIS or other system to collect the location point.

Abstract: Disclosed herein is a method of operating a plenoptic data storage system. The method may include obtaining plenoptic image data from a plenoptic camera array, generating additional information pertaining to the plenoptic image data, performing compression-coding on the plenoptic image data, and storing the additional information and the compression-coded plenoptic image data in a storage device in accordance with a storage format.

Abstract: The present invention provides markers, marker signatures and molecular targets that correlate with dysfunction of immune cells and are advantageously independent of the immune cell activation status. The present markers, marker signatures and molecular targets provide for new ways to evaluate and modulate immune responses. Specifically, GATA3 and/or FOXO1 modulation are provided for use as markers, marker signatures and molecular targets. Therapeutic methods are also provided to treat a patient in need thereof who would benefit from an increased immune response.

Abstract: It is an object to provide a method for producing a diamond substrate effective for reducing various defects including dislocation defects and a foundation substrate used for the same. This object is achieved by a foundation substrate for forming a diamond film by a chemical vapor deposition method, wherein an off angle is provided to the surface of the foundation substrate with respect to a predetermined crystal plane orientation.

Abstract: The present invention provides methods for analyzing polynucleotides such as genomic DNA. In some embodiments, the disclosure provides a method for preparing and amplifying a genomic DNA library in situ in a fixed biological sample. The method comprises treating a fixed biological sample with an insertional enzyme complex to produce tagged fragments of genomic DNA. The method further comprises circularizing the tagged fragments of genomic DNA. The method further comprises amplifying the tagged fragments of genomic DNA.

Abstract: The present invention is directed to methods of diagnosing, prognosing, and monitoring cancer in a subject. These methods involves selecting a subject having cancer, and obtaining, from the selected subject, a sample containing exosomal DNA. The presence or absence of one or more mutations in BRAF and/or EGFR is detected in the exosomal DNA sample from the subject, and a diagnosis and/or prognosis of the cancer is given based on the detection of the one or more mutations in BRAF and/or EGFR. The present invention further relates to methods of treating a subject having cancer and/or monitoring a subject response to therapy based on the detection of one or more mutations in BRAF and/or EGFR in the exosomal DNA sample.

Abstract: An image forming apparatus includes a plurality of temperature-influence members, a first-point temperature acquisition unit, a second-point temperature estimation unit, and a controller. The plurality of temperature-influence members have influence on a temperature of a recording medium on which an image is formed. The first-point temperature acquisition unit is configured to detect or estimate a temperature of the recording medium at a first point. The second-point temperature estimation unit is configured to estimate a temperature of the recording medium at a second point, based on a detection result of at least one of a temperature of the recording medium at a point different from the second point and a temperature of a member or atmosphere. The controller is configured to control the plurality of temperature-influence members, based on an acquisition result from the first-point temperature acquisition unit and an estimation result from the second-point temperature estimation unit.

Abstract: The present invention relates to a bioinformation processing analysis method for the identification and quantification of O-linked glycopeptide using high resolution mass spectrum. Particularly, according to the bioinformation processing analysis method of the present invention, the quantitative changes of O-linked glycopeptide containing non-informed sugar chains included in various samples can be efficiently and accurately analyzed; the prediction or diagnosis of disease including cancer can be made easy by using a high resolution mass spectrometer; or the investigation of O-linked glycopeptide structure of a therapeutic glycoprotein can be efficiently achieved.

Abstract: Disclosed in the present invention are a thiazolidone spiro pyrimidine trione compound, a preparation method therefor and uses thereof, the compound having a structure represented by formula (I). In the formula, the definitions of the substituents are described in the specification and the claims. The thiazolidone spiro pyrimidine trione compound in the present invention has high in vivo and in vitro antibacterial activity, has better metabolic properties, and is obviously superior to existing compounds of the same kind.

Abstract: A method for managing a power load of a grid includes performing a statistic-based distribution estimation of a composite load model using static and dynamic models with Gibbs sampling; deriving a distribution estimation of load model coefficients; and controlling grid power based on a simulation, a prediction, a stability analysis or a reliability analysis with the load model coefficients.

Abstract: The present invention pertains to field of pharmaceutical chemicals, and relates to thiazole inner salt compounds, preparation methods and uses thereof. Specifically, the present invention relates to a compound of Formula I, hydrates or pharmaceutically acceptable salts thereof. The compound of Formula I of the present invention is a potent cross-linking protein cleavage agent, has a stable structure, good physical and chemical properties, and good pharmacological activities, and is suitable for large scale production to obtain samples with stable, controllable and reliable quality, thereby being suitable for pharmaceutical development.

Abstract: Systems and methods for predicting wait time in a parking area are disclosed herein. The systems and methods include determining how long a sensing vehicle has been within a parking area without parking. Using this information, the method determines the estimated wait time for the parking area and transmits guidance to one or more recipient vehicles. This helps with efficient selection of parking areas, saving gas and preventing congestion on roadways.

Abstract: Disclosed is a device and a method for measuring stream water depth in real-time through positioning data filtering to ensure the reliability of the measured water depth data even when the stream water depth measurement data is filtered and applied to a small stream having a small basin area and a steep slope. The device for measuring stream water depth in real-time through positioning data filtering includes: a measuring part for measuring the water depth of a stream to be measured; a positioning data filtering part for filtering the water depth data measured by the measuring means by a local linear regression-based bivariate scatterplot smoothing technique through elastic bandwidth application; and a water depth calculating part for calculating a water depth of the stream to be measured by using the positioning data filtered by the positioning data filtering part, and minimizing the uncertainty of the water depth measurement.

Abstract: The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the following formula (I): wherein X1 represents a nitrogen atom or CR9, R1 represents a hydrogen atom, a C1-C6 alkyl group, or a C1-C6 alkoxy group, R2 represents a halogen atom, R3 represents a hydrogen atom or a halogen atom, R4 represents a hydrogen atom or a halogen atom, and R5 represents a C1-C3 alkylsulfonyl group, a substituted C1-C6 alkyl group, a substituted C1-C6 haloalkyl group, a substituted C1-C6 alkoxy group, or a substituted C1-C6 alkylamino group, or a pharmacologically acceptable salt thereof.