Patents Assigned to INSTITUTE
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Publication number: 20210211336Abstract: Disclosed herein are a synchronization apparatus and method for a upstream system. The synchronization apparatus for a upstream system includes one or more processors, and execution memory for storing at least one program that is executed by the one or more processors, wherein the at least one program is configured to receive a signal and calculate a first channel estimation value for the received signal using a predefined pilot, and calculate a second channel estimation value using a predefined complementary pilot and the first channel estimation value.Type: ApplicationFiled: May 4, 2020Publication date: July 8, 2021Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Kwan-Woong RYU, Jin-Hyuk SONG, Joon-Young JUNG, Dong-Joon CHOI
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Publication number: 20210207205Abstract: A PCR reaction vessel includes: a substrate; a channel formed on the substrate; a pair of filters, a first filter and a second filter, provided at respective ends of the channel; a pair of air communication ports, a first air communication port and a second air communication port, that communicate with the channel through the first filter and the second filter; a thermal cycle region formed between the first filter and the second filter in the channel; a branch point formed between the first filter and the second filter in the channel; a branched channel whose one end is connected to the branch point; and a sample introduction port formed at the other end of the branched channel.Type: ApplicationFiled: March 23, 2021Publication date: July 8, 2021Applicants: Nippon Sheet Glass Company, Limited, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, Go!Foton, Inc.Inventors: Takashi FUKUZAWA, Hidenori NAGAI, Naofumi NISHIZAWA
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Publication number: 20210209744Abstract: A system for establishing a junction trace of an assembly includes a surface model creating module, a processing module, and a material inspection module. The assembly includes a first part and a second part assembled with each other. The surface model creating module scans the first part and the second part to separately establish first surface model data and second surface model data. The processing module establishes assembled surface model data according to the first surface model data and the second surface model data, determines a junction region from the assembled surface model data, and determines inspection points mapped on the assembly according to the junction region. The material inspection module inspects materials of the assembly at the inspection points. The processing module establishes a junction trace of the first part and the second part in the assembly according to a material inspection result.Type: ApplicationFiled: March 5, 2020Publication date: July 8, 2021Applicant: Industrial Technology Research InstituteInventors: Bing-Cheng Hsu, Cheng-Kai Huang, Jan-Hao Chen, Chwen-Yi Yang, Yi-Ying Lin
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Publication number: 20210205381Abstract: Provided are engineered phages populations, which are homogeneous in length, as well as methods of making and methods of using such phages. Also provided are engineered chlorotoxin-phages as well as their methods of making and using. The disclosed homogeneous phage populations and chlorotoxin-phages may be used, for example, for treating and/or imaging tumors, such as central nervous system tumors.Type: ApplicationFiled: March 22, 2021Publication date: July 8, 2021Applicant: Massachusetts Institute of TechnologyInventors: Angela M. Belcher, Uyanga Tsedev, Fred Lam
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Publication number: 20210204967Abstract: A guide for positioning an orthopaedic guide pin on a bone structure includes a base having an upper face, a lower face intended to bear against the bone structure, and a through-hole for the pin, said guide including several bearing members able to move in guide holes formed in the base, wherein each bearing member has a lower end facing the lower face and is able to be moved selectively between a retracted position inside the guide hole and at least one deployed position in which the bearing member protrudes from the lower face so as to have a salient lower end intended to bear against the bone structure in order to allow the base to be inclined.Type: ApplicationFiled: March 22, 2021Publication date: July 8, 2021Applicant: SHOULDER FRIENDS INSTITUTEInventors: Yves LEFEBVRE, Stephane AUDEBERT, Johannes BARTH, Christophe CHAROUSSET, Jerome GARRET, David GALLINET, Arnaud GODENECHE, Jacques GUERY, Thierry JOUDET
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Publication number: 20210207290Abstract: A method for isolating exosomes from a biological sample may include synthesizing a first nanofibrous substrate by coaxial electrospinning of a core polymer solution and a shell polymer solution. The shell polymer solution may include gelatin. A method for isolating exosomes may further include obtaining a second nanofibrous substrate by immobilizing an antibody, such as CD63, CD9, and CD81 to the first nanofibrous substrate, capturing the exosomes from the biological sample by incubating the biological sample with the second nanofibrous substrate, and releasing the captured exosomes from the second nanofibrous substrate by incubating the second nanofibrous substrate with water at a temperature of 37° C.Type: ApplicationFiled: March 19, 2021Publication date: July 8, 2021Applicants: National institute of genetic engineering and biotechnologyInventor: Matin Mahmoudifard
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Publication number: 20210206064Abstract: A three-dimensional printing apparatus having electrostatic auxiliary, including a printing platform, a feeding device, a nozzle, and a high voltage power supply, is provided. The feeding device and the nozzle are disposed above the printing platform. The nozzle is connected to the feeding device and is located between the feeding device and the printing platform. A distance between the nozzle and the printing platform is less than or equal to 1 cm. The high voltage power supply has an output end electrically connected to the nozzle and a ground end electrically connected to the printing platform.Type: ApplicationFiled: December 22, 2020Publication date: July 8, 2021Applicant: Industrial Technology Research InstituteInventors: Hsin-Hsin Shen, Chang-Chou Li, Li-Wen Lai, Yu-Bing Liou, Ying-Wen Shen
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Publication number: 20210207175Abstract: A compound for improving the gene editing specificity and application thereof. Specifically disclosed is a compound represented by formula I or a use of a pharmaceutically acceptable salt thereof. The compound and the pharmaceutically acceptable salt thereof are used for preparing an inhibitor, a composition, or a formulation for inhibiting gene editing and/or improving the gene editing specificity. The structure of the formula I is as stated in the description. The compound can significantly improve the accuracy of CRISPR gene editing, thereby providing a simple and high-efficient policy for accurate gene editing.Type: ApplicationFiled: December 14, 2020Publication date: July 8, 2021Applicants: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, SHANGHAITECH UNIVERSITYInventors: Jia Liu, Jiajia Dong
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Publication number: 20210208565Abstract: A method for inspecting defects of a machining path is provided. The method includes the following steps. Firstly, a contour mold with a plurality of surface nodes is generated according to a machining program code. Next, a normal vector of each surface node of the contour mold is calculated. Then, a tangent vector of a block of the machining program code corresponding to the normal vector is calculated. Afterwards, an error information is obtained according to a relation between the normal vector and the tangent vector. When the error information is greater than a predetermined value, a defect information is shown on the contour mold.Type: ApplicationFiled: May 13, 2020Publication date: July 8, 2021Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Cheng-Wei WANG, Kuo-Hua CHOU, Chien-Chih LIAO, Jen-Ji WANG
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Publication number: 20210210745Abstract: An electrode and a lithium-ion battery employing the electrode are provided. The electrode includes an active layer, a conductive layer, and a non-conductive layer. The conductive layer is disposed on the top surface of the active layer. The conductive layer includes a first porous film and a conductive lithiophilic material, and the conductive lithiophilic material is within the first porous film and covers the inner surface of the first porous film. The non-conductive layer includes a second porous film and a non-conductive lithiophilic material, and the non-conductive lithiophilic material is within the second porous film and covers the inner surface of the second porous film. The conductive layer is disposed between the active layer and the non-conductive layer. The binding energy (?G) of the lithiophilic material with lithium is less than or equal to ?2.6 eV.Type: ApplicationFiled: December 17, 2020Publication date: July 8, 2021Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Wei-Hsin WU, Chih-Ching CHANG, Yu Fang HUANG, Li-Ju CHEN, Chia-Chen FANG
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Publication number: 20210210965Abstract: A plurality of battery packs is provided in communication with an energy monitoring and control system. Each battery pack includes a plurality of battery cells that collectively dictate the capabilities of the battery pack. The energy monitoring and control system determines a plurality of pack charging or pack discharging parameters for each battery pack that, when performed, achieve one or more performance metrics at a user level (e.g., performance metrics of each battery pack within a system of multiple battery packs). The battery pack further determines a plurality of cell charging or cell discharging parameters for each battery cell based upon the determined plurality of pack charging or pack discharging parameters for each battery cell that, when performed, achieve one or more performance metrics at a battery level (e.g., performance metrics of different cells of each battery pack).Type: ApplicationFiled: December 15, 2020Publication date: July 8, 2021Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Mahshid ROUMI, Farshid ROUMI
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Publication number: 20210205210Abstract: The purpose of the present invention is to provide an ointment preparation in which both separation over time and discoloration over time are suppressed. Both separation over time and discoloration over time are suppressed in: a topical composition containing (A) 30-60 weight % of zinc chloride, a specific (B) inorganic powder and a specific (C) additive, and (D) a solvent; and a topical composition containing (A) 30-60 weight % of zinc chloride, a specific (B) inorganic powder, and (D) a solvent.Type: ApplicationFiled: May 29, 2019Publication date: July 8, 2021Applicants: JINNO INSTITUTE, OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Masato SHIGEYAMA, Toshiya NAGIRI, Yuki TAKEUCHI, Yu MIMA, Katsunori SHIRAI, Toshimitsu TERAO
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Publication number: 20210207082Abstract: A spherical 3D tumor spheroid according to an aspect has an appropriate diameter, roundness and specificity so as to be suitably used in vitro, and expresses an ECM structure similar to that of in vivo tumor, and thus may be used in evaluating the efficacy of drug for treating various types of tumors.Type: ApplicationFiled: December 18, 2020Publication date: July 8, 2021Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sang-Heon KIM, Seung Ja OH, Wooshik CHOI, Inyeong BAE
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Publication number: 20210204890Abstract: Systems and methods for obtaining scattering images during computed tomography (CT) imaging are provided. Two gratings or grating layers can be disposed between the object to be imaged and the detector, and the gratings or grating layers can be arranged such that primary X-rays are blocked while scattered X-rays that are deflected as they pass through the object to be imaged reach the detector to generate the scattering image.Type: ApplicationFiled: February 17, 2017Publication date: July 8, 2021Applicant: RENSSELAER POLYTECHNIC INSTITUTEInventors: Ge WANG, Wenxiang CONG
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Publication number: 20210209950Abstract: A method for generating data sets of a UAV, performed by a data set generation apparatus, may comprise obtaining flight environment information including a moving object; obtaining flight data including first physical information and first sensor information of the UAV in a flight environment based on the flight environment information; obtaining second physical information and second sensor information of the UAV when the moving object exists, based on the flight data, and generating a first data set based on the second physical information and the second sensor information; obtaining third physical information and third sensor information of the UAV when the moving object does not exist, based on the flight data, and generating a second data set based on the third physical information and the third sensor information; and combining the first data set and the second data set to generate a third data set.Type: ApplicationFiled: December 16, 2020Publication date: July 8, 2021Applicant: Electronics and Telecommunications Research InstituteInventor: Jeong Gi YANG
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Publication number: 20210205395Abstract: A composition is provided for promoting skeletal muscle oxidative muscle fiber generation. The composition comprises a Lycium barbarum water extract. The Lycium barbarum extract comprises polysaccharide, Lycium barbarum flavone, carotenoid, polyphenol, and Lycium barbarum pigment. The composition may further comprise one or more pharmaceutically acceptable excipients selected from such as a solvent, a co-solvent, an emulsifier, a preservative, a buffer, a protein powder, or a combination thereof. The composition may be used as medicine, functional product, or food supplement.Type: ApplicationFiled: December 30, 2020Publication date: July 8, 2021Applicant: Institute of Biophysics, Chinese Academy of SciencesInventors: Chang Chen, Jiao Meng, Zhenyu Lv, Chuanxin Sun, Xinhua Qiao
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Publication number: 20210206777Abstract: A lycorine derivative of Formula (I), and a pharmaceutically acceptable salt, a preparation method, a pharmaceutical composition and use thereof wherein the lycorine derivative has obvious antiviral activity and is useful in the treatment of viral diseases such as hand-foot-mouth disease.Type: ApplicationFiled: July 27, 2018Publication date: July 8, 2021Applicants: SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD, BEIJING DYNE HIGH-TECH PEDIATRIC PHARMACEUTICAL R&D INSTITUTE CO., LTD.Inventors: Xiandao PAN, Yajun YANG, Longying SHEN, Wensheng ZHENG, Shuwang HE, Shiqiang YAN, Yajun JING
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Publication number: 20210205234Abstract: A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.Type: ApplicationFiled: February 1, 2021Publication date: July 8, 2021Applicants: OSAKA UNIVERSITY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Hiroyuki TANAKA, Kiyoshi OKADA, Hideki YOSHIKAWA, Koji SUZUKI, Mitsuhiro EBARA
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Publication number: 20210206841Abstract: Provided herein are methods and compositions for disrupting biofilms in vitro and in vivo. Also disclosed are antibodies comprising a specified heavy chain (HC) immunoglobulin variable domain sequence and/or a specified light chain (LC) immunoglobulin variable domain sequence.Type: ApplicationFiled: January 28, 2021Publication date: July 8, 2021Applicant: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITALInventors: Steven D. Goodman, Lauren O. Bakaletz
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Publication number: 20210207203Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide robust CRISPR-based nucleic acid amplification methods and systems. Embodiments disclosed herein can amplify both double-stranded and single-stranded nucleic acid targets. Moreover, the embodiments disclosed herein can be combined with various detection platforms, for example, CRISPR-SHERLOCK, to achieve detection and diagnostic with attomolar sensitivity. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.Type: ApplicationFiled: June 26, 2019Publication date: July 8, 2021Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Feng Zhang, Max Kellner, Jonathan Gootenberg, Omar Abudayyeh