Patents Assigned to INSTITUTE
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Patent number: 12062121Abstract: A method to generate a digital avatar simulating a human for behavioral empathy and understanding is described. The method includes training a neural network to generate the digital avatar to simulate the human according to a vector of human attributes and generate responses in response to interactions with a user based on the vector of human attributes. The method also includes interacting, by the user, with the digital avatar, in which the digital avatar initially having a similar background and attributes as the user. The method further includes modifying, over time, the attributes of the digital avatar to represent a target background and a target set of attributes different from the user.Type: GrantFiled: October 2, 2021Date of Patent: August 13, 2024Assignee: TOYOTA RESEARCH INSTITUTE, INC.Inventors: Nikos Arechiga, Matthew Len Lee, Charlene C. Wu, Shabnam Hakimi
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Patent number: 12063565Abstract: A Multi-Access Edge Computing (MEC) system is provided. The MEC system includes a user equipment (UE), an MEC device, and a core network. The MEC device includes a relay User Plane Function (UPF) module, a first UPF module, and a second UPF module. The core network performs a UPF path management corresponding to the UE based on a notification of the MEC device. When the UE attaches to a network, the MEC device establishes an idle session between the UE and the relay UPF module. When the MEC device determines that a service for the UE needs to be switched from the first UPF module to the second UPF module and the second UPF module has not been activated, the MEC device notifies the core network to switch the service for the UE from the first UPF module to the relay UPF module first.Type: GrantFiled: June 7, 2022Date of Patent: August 13, 2024Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Wei-Cheng Wang, Kuo-Wei Wen, Tsun-Chieh Chiang
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Patent number: 12062796Abstract: A catalyst for an oxygen reduction reaction containing catalyst particles having a shell-core structure containing a PtCo alloy or a PtCoMn alloy as a core, and platinum as a shell layer. A specific plane of a face-centered cubic lattice is formed by a plurality of platinum atoms contained in the shell layer, and a lattice constant of the plane of the face-centered cubic lattice on the catalyst particle surface is 3.70 ? or more and 4.05 ? or less (in a PtCo alloy), or 3.870 ? or more and 4.10 ? or less (in a PtCoMn alloy). A catalyst design method includes a step of calculating, with respect to an orientation plane such as the plane formed by platinum atoms of the shell layer, adsorption energies for an oxygen molecule, an OH group and a water molecule by first-principles calculation based on density functional theory.Type: GrantFiled: December 13, 2021Date of Patent: August 13, 2024Assignees: TANAKA KIKINZOKU KOGYO K.K., NATIONAL INSTITUTE OF TECHNOLOGYInventors: Minoru Ishida, Koichi Matsutani, Hiroshi Nakanishi, Hideaki Kasai, Bhume Chantaramolee, Susan Menez Aspera
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Patent number: 12062040Abstract: A block consensus method of a computing device is provided. The computing device receives a delegate request message including transaction hashes from each of a plurality of nodes, generates a prepared block including transaction hashes based on the delegate request message, and transmits a prepare message including the prepared block to the nodes. The computing device receives a commit message including a proof of consensus on a validity of the prepared block from the nodes, and transmits a reply message including a final block decided based on the commit message.Type: GrantFiled: December 30, 2021Date of Patent: August 13, 2024Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Heesang Jin, Jintae Oh, Ki Young Kim, Young-Chang Kim
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Patent number: 12062205Abstract: Disclosed are camera pose determination methods and apparatuses. The method includes determining first pixels in a current image and second pixels in a previous image, determining second pixel points with the preconfigured semantics in a previous image frame before the current image frame, the first pixel points corresponding to at least a portion of the second pixel points, determining an error between the first pixel points and the second pixel points, and a camera pose change value of the current image frame relative to the previous image frame based on the error, and determining a camera pose of the current image based on a camera pose of the previous image and the camera pose change. Related devices and storage media are also disclosed.Type: GrantFiled: August 5, 2019Date of Patent: August 13, 2024Assignee: NANJING INSTITUTE OF ADVANCED ARTIFICIAL INTELLIGENCE, LTD.Inventor: Qinrui Yan
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Patent number: 12060391Abstract: Embodiments disclosed herein provide nucleic acid constructs and methods of use thereof that induce a live cell to give off sub-samples of the cell's cytosolic content. The tem “cell” as used herein may be any cell type. In certain example embodiments, the cells are mammalian cells. The sampling can be general or can be targeted to a particular class of molecules or to specific types of molecules. The constructs facilitate generation of a read-out for high-throughput screens by combining engineered export with simple bulk sample and sample processing. Live cell sampling enables time course measurements and expands, for example, the applicability of transcriptional profiles obtained by single cell gene expression analysis.Type: GrantFiled: March 16, 2016Date of Patent: August 13, 2024Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Paul Blainey, Jacob Borrajo
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Multi-functional computer-aided gastroscopy system optimized with integrated AI solutions and method
Patent number: 12062169Abstract: A multi-functional, computer-aided gastroscopy system optimized with integrated AI solutions is disclosed. The system makes use of multiple deep-learning neural models to achieve low latency and high-performance requirements for multiple tasks. The optimization is made at three levels: architectural, modular and functional level. At architectural level, the models are designed in such a way that it is able to accomplish HP infection classification and detection of some lesions for one inference in order to reduce computation costs. At modular level, as a sub-model of HP infection classification, the site recognition model is optimized with temporal information. It not only improves the performance of HP infection classification, but also plays important roles for lesion detection and procedure status determination. At functional level, the inference latency is minimized by configuration and resource aware optimization.Type: GrantFiled: April 25, 2022Date of Patent: August 13, 2024Assignee: HONG KONG APPLIED SCIENCE AND TECHNOLOGY RESEARCH INSTITUTE COMPANY LIMITEDInventors: Xuejian He, Lu Wang, Ping Shun Leung -
Patent number: 12059664Abstract: A method of producing a substance includes a producing step of producing a new substance by, in a state in which a raw material absorbing giant pulse laser light is disposed inside a base material or in a state in which the base material and the raw material are brought into contact with each other and are clamped together, performing irradiation with the giant pulse laser light such that the raw material absorbs the giant pulse laser light and thereby generating shock waves such that at least the raw material undergoes phase transition.Type: GrantFiled: May 14, 2019Date of Patent: August 13, 2024Assignee: INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCESInventors: Takunori Taira, Arvydas Kausas
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Patent number: 12060389Abstract: An enterovirus multi-antigen epitope fusion protein, a gene, a vaccine and a preparation method thereof are provided, relating to the field of vaccine preparation technologies. The amino acid sequence of the enterovirus multi-antigen epitope fusion protein is shown in SEQ ID NO: 4. The vaccine is prepared by adopting the preparation method of a genetically engineered protein vaccine, and the prepared vaccine has stronger specificity. After protein purification, there are fewer impure proteins and more specific antigen proteins, thus improving the effectiveness and safety of the combined vaccine.Type: GrantFiled: January 13, 2024Date of Patent: August 13, 2024Assignee: INSTITUTE OF MEDICAL BIOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCESInventors: Longding Liu, Huiwen Zheng, Heng Li, Xin Zhao, Li Yu, Guorun Jiang, Dandan Li, Heng Zhao, Ying Zhang, Yun Liao, Haijing Shi
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Patent number: 12060291Abstract: Disclosed is a method for the treatment and resource utilization of acidic organic wastewater, comprising: (1) performing activated sludge treatment on acidic organic wastewater; and (2) performing microalgae treatment on the acidic organic wastewater treated in step (1). By means of the combination of activated sludge treatment and microalgae treatment, the present invention can significantly reduce the COD of the acidic organic wastewater. In some embodiments, the use of acclimated activated sludge or activated sludge having a specific microbial flora structure can not only improve the treatment efficiency while shortening the treatment time, but also omit a pH value adjustment step without causing sludge accumulation.Type: GrantFiled: October 17, 2019Date of Patent: August 13, 2024Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC NANJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.Inventors: Haitao Li, Songbai Mao, Dong Wang, Xi Chen
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Patent number: 12062154Abstract: An image correcting method of the present invention includes: a step of performing a preprocessing process on an original image to generate a mask image including only an erased area of the original image; a step of predicting, by using generative adversarial networks, an image which is to be synthesized with the erased area in the mask image; and a step of synthesizing the predicted image with the erased area of the original image to generate a new image.Type: GrantFiled: March 5, 2020Date of Patent: August 13, 2024Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Young Joo Jo, Jong Youl Park, Yu Seok Bae
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Patent number: 12060352Abstract: The disclosure provides substituted pyrrolo[2,3-d]pyrimidine compounds of Chemical Formula 1 and compositions and uses thereof, wherein R1-R7, X, Y, Cy, m and n are defined in the disclosure. The compounds are useful for inhibiting ENPP1, activating the STING pathway, and treating cancer.Type: GrantFiled: March 29, 2022Date of Patent: August 13, 2024Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seo Jung Han, Sang Hee Lee, Hee Jin Jeong, Hye Lim Lee, Chan Sun Park, Sung Joon Kim
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Patent number: 12062555Abstract: The disclosure provides a micro light-emitting diode mass transfer apparatus and method. The micro light-emitting diode mass transfer apparatus includes a solution container, display backplanes, a solution drive assembly and a liquid level control assembly. The solution container contains a transfer solution, and micro light-emitting diodes to be transferred float on the liquid surface of the transfer solution. The display backplanes are submerged in the transfer solution and each provided with a plurality of chip mounting cells; mounting cell opening directions of the plurality of chip mounting cells face toward the micro light-emitting diodes; and at least one of the chip mounting cells is exposed on the liquid surface. The solution drive assembly is disposed in the solution container. The liquid level control assembly is configured to control a liquid level of the transfer solution in the solution container.Type: GrantFiled: July 23, 2021Date of Patent: August 13, 2024Assignee: CHONGQING KONKA PHOTOELECTRIC TECHNOLOGY RESEARCH INSTITUTE CO., LTD.Inventor: Qiang Li
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Patent number: 12062884Abstract: Provided is a laser device according to embodiments of the inventive concept comprising a substrate including a gain region, a phase control region, and a tuning region arranged along a first direction, the substrate having an air gap which extends from the phase control region to the tuning region, an upper clad layer on the substrate, a waveguide structure extending in the first direction between the upper clad layer and the substrate, a first upper electrode disposed on the upper surface of the upper clad layer of the tuning region, and a lower electrode disposed on a lower surface of the substrate and extending from the gain region to the tuning region, wherein the air gap may have a larger width than the waveguide in a second direction crossing the first direction.Type: GrantFiled: February 23, 2021Date of Patent: August 13, 2024Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Oh Kee Kwon, Kisoo Kim, Su Hwan Oh, Chul-Wook Lee
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Patent number: 12058988Abstract: The present disclosure provides a warm water immersion-based hatching method of silkworm eggs, belonging to the technical field of sericulture production. In the present disclosure, a warm water treatment is conducted on silkworm eggs of a bivoltine silkworm variety in production, and a water temperature and an immersion time are optimized to ensure a higher hatching rate. The silkworm eggs are subjected to the warm water immersion at 49° C. to 51° C. for 15 s to 23 s to rapidly hatch the silkworm eggs without diapause.Type: GrantFiled: May 12, 2022Date of Patent: August 13, 2024Assignee: SERICULTURE AND AGRI-FOOD RESEARCH INSTITUTE, GUANGDONG ACADEMY OF AGRICULTURAL SCIENCESInventors: Dongxu Xing, Qiong Yang, Sentai Liao, Yang Xiao, Qingrong Li
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Patent number: 12060070Abstract: The disclosure generally relates to methods for assisting a driver of a vehicle that include monitoring the driver's actions, during a first portion of time that starts when the driver begins to engage in a surveillance type action and ends when the driver ends the surveillance type action, activating one or more feedback devices, when the driver engages in a surveillance type action, monitoring the driver's actions during a second portion of time that beings when the driver ends the surveillance type action, and ends when the driver begins the surveillance type action, and activating one or more feedback devices, during the second portion of time when the driver engages in a driving maneuver and fails to engage in the surveillance type action.Type: GrantFiled: April 25, 2022Date of Patent: August 13, 2024Assignees: TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Jaime S. Camhi, Manuel Ludwig Kuehner, Hiroshi Yasuda
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Patent number: 12060332Abstract: Disclosed herein are compounds and methods for reducing the risk of developing, preventing, or treating graft versus host disease (GVHD) in a subject. The compounds can concurrently block Aurora kinase A and JAK2 signal transduction which synergistically suppresses alloreactive human T-cells in vitro, prevents xenogeneic graft-versus-host disease without impairing anti-tumor responses, and promotes the development and suppressive potency of CD39+ inducible Treg. In certain aspects, disclosed are compounds of Formula I-V.Type: GrantFiled: January 19, 2023Date of Patent: August 13, 2024Assignee: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.Inventors: Brian Betts, Said M. Sebti, Harshani Lawrence, Nicholas Lawrence, Claudio Anasetti, Joseph Pidala
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Patent number: 12061802Abstract: Disclosed herein are a dynamic memory management apparatus and method and a computer-readable storage medium for the same. The dynamic memory management method includes defining a shadow area mapped to a memory area, setting a coloring value in the shadow area, and permitting or denying access to the memory area based on the coloring value when accessing the memory area.Type: GrantFiled: October 20, 2022Date of Patent: August 13, 2024Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Hong-Il Ju, Dong-Wook Kang, Gae-Il An, Bo-Heung Chung, Byeong-Cheol Choi
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Publication number: 20240261424Abstract: The present invention relates to an antibody drug conjugate in which an antibody that binds to tissue factor and Dxd that is the cytotoxic agent are bound via a linker composed of maleimide caproyl-glycine-glycine-phenylalanine-glycine.Type: ApplicationFiled: March 16, 2021Publication date: August 8, 2024Applicants: NATIONAL CANCER CENTER, RIN INSTITUTE INC.Inventors: Yasuhiro MATSUMURA, Ryo TSUMURA
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Publication number: 20240263415Abstract: An unpowered-filtering sewage cleaning device includes a sewage discharge mechanism, a water conveyance mechanism, a filtration mechanism, a water guidance mechanism, a water discharge mechanism, a support mechanism, and a transmission mechanism. The transmission mechanism includes a main transmission shaft, a clutch mechanism, and an auxiliary transmission shaft. The main transmission shaft is mounted with the auxiliary transmission shaft through the clutch mechanism. In case of disengagement of the clutch mechanism, the main transmission shaft rotates, while the auxiliary transmission shaft does not rotate. In case of engagement of the clutch mechanism under a pressure, the main transmission shaft drives the auxiliary transmission shaft to rotate coaxially. The water conveyance mechanism, the filtration mechanism, and the water guidance mechanism are mounted with the main transmission shaft. The sewage discharge mechanism is mounted with the auxiliary transmission shaft.Type: ApplicationFiled: November 21, 2022Publication date: August 8, 2024Applicant: FARMLAND IRRIGATION RESEARCH INSTITUTE, CAASInventors: Peng Li, Qibiao Han, Jinshan Li, Hao Li, Yang Liu, Yayang Feng