Patents Assigned to INSTITUTE
  • Patent number: 12054764
    Abstract: Provided herein are methods for screening biological functions of microscale biological systems comprises segregating each microscale biological system from a set of microscale biological systems to be screened into individual discrete volumes, the individual discrete volume comprising a first polymer. The first polymer is then forced or allowed to polymerize to form a set of polymerized beads that encapsulate an individual microscale biological system. The polymerized beads are further encapsulated in a second droplet comprising a second polymer and one or more reporter elements. The reporter elements are configured to produce a readout upon detecting the absence or presence of a biological function to be screened. The second polymer is then forced or allowed to polymerize to form an outer capsule around each individual bead thereby forming a set of encapsulated beads. One or more biological functions of the double-encapsulated system are identified by detecting the readout of the reporters.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: August 6, 2024
    Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Paul Blainey, Navpreet Ranu
  • Patent number: 12054404
    Abstract: A preparation method and an application of a clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics are provided, which relate to the field of water environment treatments. A clay/tannic acid/metal ion composite adsorbent is prepared, preparation method and operation process are simple, synthesis time is short, and yield is large. A raw material used is tannic acid, which has a wide range of sources, is non-toxic, biodegradable, and has no risk of secondary pollution, due to abundant phenolic hydroxyl groups in tannic acid, the tannic acid can not only chelate with the metal ions, but also adsorb pollutants from water, when combined with the clay and the metal ions, a composite body is formed, which has a rougher surface, and adsorption active sites are increased, thereby effectively increasing adsorption, and improving an adsorption performance for pollutants. The clay/tannic acid/metal ion composite adsorbent has good adsorption effect for antibiotics.
    Type: Grant
    Filed: November 16, 2023
    Date of Patent: August 6, 2024
    Assignees: NANJING UNIVERSITY, QUANZHOU INSTITUTE FOR ENVIRONMENTAL PROTECTION INDUSTRY, NANJING UNIVERSITY
    Inventors: Hu Yang, Qianqian Chang
  • Patent number: 12058246
    Abstract: A secret key sharing system includes a transceiver in a first layer, a plurality of transceivers in a second layer, and a plurality of transceivers in a third layer. The transceivers in the second layer receive a first random number from the transceiver in the first layer via a directional carrier wave. The transceivers in the third layer receive a second random number from one of the transceivers in the second layer via the carrier wave. The transceiver in the first layer and the transceivers in the second layer share a first secret key based on the first random number, and the one of the transceivers in the second layer and the plurality of transceivers in the third layer share a second secret key based on the second random number.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: August 6, 2024
    Assignee: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
    Inventors: Hiroyuki Endo, Masahide Sasaki
  • Patent number: 12056427
    Abstract: A numerical experimental method for urban waterlogging includes the following steps: acquiring raw data of an urban underlying surface; batch-processing urban waterlogging modeling data; batch-running urban waterlogging numerical experimental models; batch-processing urban waterlogging numerical experimental results; and displaying and analyzing the batch-processed urban waterlogging numerical experimental results. The numerical experimental method constructs a numerical experimental process, which can perform an unlimited number of repeated experiments in the numerical simulation process of urban waterlogging and achieve batch-running of data preprocessing, model operation, and data post-processing processes. Therefore, the numerical experimental method has the advantages of high efficiency, high convenience, high reliability, and low cost.
    Type: Grant
    Filed: November 22, 2023
    Date of Patent: August 6, 2024
    Assignee: CHINA INSTITUTE OF WATER RESOURCES AND HYDROPOWER RESEARCH
    Inventors: Chao Mei, Hongyuan Shi, Jiahong Liu, Hao Wang, Xichao Gao, Jia Wang, Tianxu Song
  • Patent number: 12057886
    Abstract: An optical transceiver supports bidirectional communication with another optical transceiver that is a communications partner via a single-mode optical fiber. A surface emitting laser has a T-band oscillation wavelength that is shorter than the cutoff wavelength of the optical fiber. A photodetector has detection sensitivity with respect to the T band. A planar lightwave circuit couples the optical fiber, the surface emitting laser, and the photodetector.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: August 6, 2024
    Assignee: TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Susumu Kinoshita, Fumio Koyama, Xiaodong Gu
  • Patent number: 12054454
    Abstract: The present invention discloses a method for catalyzing olefin carbonylation, including the following steps: using cyclic alkylcarbene iridium as a catalyst and an olefin as a raw material to carry out carbonylation reaction to generate aldehydes, wherein a structural formula of the cyclic alkylcarbene iridium is as follows: wherein Dipp is 2,6-diisopropylbenzene; R1 and R2 are methyl or ethyl; X is Cl, Br, CH3CO2, NO3, BF4, PF6 or SbF6; wherein the olefin comprises one or more of ethylene, propylene, butylene and higher carbon olefins. According to the method for catalyzing olefin carbonylation of the present invention, by adopting an iridium catalyst, the catalytic activity is good, reaction energy consumption is reduced, and reaction temperature is fully lowered.
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: August 6, 2024
    Assignee: NANJING INSTITUTE OF MICROINTERFACE TECHNOLOGY CO., LTD
    Inventors: Xingbang Hu, Zhibing Zhang, Chenfei Yao, Lei Li, Zheng Zhou
  • Publication number: 20240259689
    Abstract: A method for decoding a 360-degree image includes: receiving a bitstream obtained by encoding a 360-degree image; generating a prediction image by making reference to syntax information obtained from the received bitstream; combining the generated prediction image with a residual image obtained by dequantizing and inverse-transforming the bitstream, so as to obtain a decoded image; and reconstructing the decoded image into a 360-degree image according to a projection format. Here, generating the prediction image includes: checking, from the syntax information, prediction mode accuracy for a current block to be decoded; determining whether the checked prediction mode accuracy corresponds to most probable mode (MPM) information obtained from the syntax information; and when the checked prediction mode accuracy does not correspond to the MPM information, reconfiguring the MPM information according to the prediction mode accuracy for the current block.
    Type: Application
    Filed: March 6, 2024
    Publication date: August 1, 2024
    Applicant: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek KIM
  • Publication number: 20240258762
    Abstract: Disclosed are a mode-locked resonator according to an embodiment and an ultrashort pulse laser comprising the mode-locked resonator. The mode-locked resonator according to an embodiment includes a resonator including a shape of a sphere; and a saturable absorber coated on a surface of the resonator, wherein the resonator is coupled with some photons traveling in a tapered optical fiber disposed near the mode-locked resonator and interacts with the saturable absorber based on a Whispering Gallery Mode (WGM).
    Type: Application
    Filed: April 20, 2023
    Publication date: August 1, 2024
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Yong-Won SONG, Hyowon MOON, Oleksiy KOVALCHUK, Sungjae LEE
  • Publication number: 20240254103
    Abstract: The present invention relates to a novel pyrimidine derivative, and a composition for preventing or treating neurodegenerative diseases and cancer, comprising same, the pyrimidine derivative having a LRRK2 protein inhibitory activity, and effectively passing through a blood-brain barrier (BBB) so as to be effectively used as a pharmaceutical composition for preventing or treating neurodegenerative diseases and cancer.
    Type: Application
    Filed: March 12, 2021
    Publication date: August 1, 2024
    Applicants: WHAN IN PHARMACEUTICAL CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Ge Hyeong LEE, Jee Yeon SEO, Jeong Heon YU, In Hae YE, Ho Chul SHIN, Jee Hee SUH, Seong Hwan KIM, Jin Sook SONG, Seong Hyeon SIM, Chong Hak CHAE, Hee Yeon KANG, Ji Hun LEE, Keon Ha HWANG
  • Publication number: 20240257468
    Abstract: Disclosed is an operation method of an electronic device, the method including: identifying a first quaternion value corresponding to rotation of a first object and a second quaternion value corresponding to rotation of a second object; identifying, on the basis of the first quaternion value, a first axis around which the first object rotates; identifying, on the basis of the second quaternion value, a second axis around which the second object rotates; identifying a first rotation angle related to rotation of the first object around the first axis, and a second rotation angle related to rotation of the second object around the second axis; identifying a first angle formed by the first and second axes; identifying a second angle corresponding to a difference between the first and second rotation angles; and determining a quaternion distance between the first and second objects on the basis of the first and second angles.
    Type: Application
    Filed: December 12, 2023
    Publication date: August 1, 2024
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Kap Kee KIM, Bonki KOO
  • Publication number: 20240259196
    Abstract: A timestamp generation method and apparatus, and an electronic device and a storage medium, which are used for solving the technical problem of recorded information being easily leaked because a trusted third party is usually needed as a timestamp authority for recording in a traditional trusted timestamp generation method. In the present invention, the method comprises: acquiring a file record; calculating a hash value of the file record; sending the hash value to a random issuer, and receiving a signature result returned by the random issuer, wherein the signature result is generated after the random issuer signs the hash value and a receiving time, and the receiving time is the time when the random issuer receives the hash value; and storing the signature result in a blockchain as a timestamp of the file record.
    Type: Application
    Filed: September 2, 2022
    Publication date: August 1, 2024
    Applicants: ELECTRIC POWER RESEARCH INSTITUTE, CHINA SOUTHERN POWER GRID, GUIZHOU POWER GRID CO., LTD.
    Inventors: Yi LUO, Jiaxiang OU, Bin QIAN, Houpeng HU, Yong XIAO, Yanhong XIAO, Ji WANG, Pengcheng LI, Mi ZHOU, Tianqiang DONG, Fan ZHANG, Xin WU, Fusheng LI, Zhenghao GAO, Xiaoming LIN, Hangfeng LI, Jianlin TANG, Zilong RAN, Xuan LUO, Wei ZHOU, Yaodan DENG
  • Publication number: 20240257305
    Abstract: A method for reconstructing an object from distorted images, according to an embodiment of the present invention, comprises the steps of: acquiring a plurality of original images including a distorted region; extracting a Fourier phase with respect to the original images; extracting a Fourier amplitude with respect to the original images; and acquiring a reconstructed image in which the distorted region has been reconstructed by performing inverse Fourier transform on a value obtained by multiplying the Fourier phase and the Fourier amplitude, wherein the step of extracting the Fourier phase and the step of extracting the Fourier amplitude are performed independently of each other.
    Type: Application
    Filed: March 28, 2022
    Publication date: August 1, 2024
    Applicant: UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventors: Chung Hun Park, Byung Jae Hwang
  • Publication number: 20240253026
    Abstract: Provided are a core-shell catalyst with improved durability and a manufacturing method thereof including irradiating ultrasonic waves to a solution containing a reducing solvent, a noble metal precursor, a transition metal precursor, and a carbon support to form a cavity due to the irradiation of the ultra-waves and forming transition metal precursor core and noble metal precursor shell particles due to a difference in vapor pressure; and nitriding the transition metal precursor core and noble metal precursor shell particles at a temperature of 450 to 550° C. and a pressure condition of 60 to 100 bar under a gaseous nitrogen source, in which the transition metal may be any one selected from the group consisting of Y, La, Ce, Zn, and Mn or combinations thereof.
    Type: Application
    Filed: January 12, 2024
    Publication date: August 1, 2024
    Applicant: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Gu-Gon PARK, Eunjik LEE, Sung-Dae YIM, Seok-Hee PARK, Minjin KIM, Young-Jun SOHN, Byungchan BAE, Seung-Gon KIM, Dongwon SHIN, Seung Wook CHOI, Hwangyeong OH, Seung Hee WOO, So Jeong LEE, Hyejin LEE, Yoon Young CHOI, Yun Sik KANG, Won-Yong LEE, Tae-Hyun YANG
  • Publication number: 20240252640
    Abstract: The presently disclosed subject matter provides for antigen-recognizing receptors that specifically target DLL3 and cells comprising such DLL3-targeted antigen-recognizing receptors. The presently disclosed subject matter further provides uses of the DLL3-targeted antigen-recognizing receptors for treatment.
    Type: Application
    Filed: February 29, 2024
    Publication date: August 1, 2024
    Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER, SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH, MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES
    Inventors: Janneke E. Jaspers, Marjan ZAMAN, Renier J. BRENTJENS
  • Publication number: 20240254514
    Abstract: Artificial expression constructs for modulating gene expression in targeted central nervous system cell types are described. The artificial expression constructs can be used to express synthetic genes or modify gene expression in GABAergic or glutamatergic neurons within the thalamus. In some cases, the artificial constructs can also be used to express synthetic genes or modify gene expression in neurons within the thalamus as well as a secondary cell type.
    Type: Application
    Filed: May 20, 2022
    Publication date: August 1, 2024
    Applicant: ALLEN INSTITUTE
    Inventors: Tanya Daigle, Edward Sebastian Lein, Boaz P. Levi, John K. Mich, Amanda Mitchell, Bosiljka Tasic, Jonathan Ting, Natalie Weed, Hongkui Zeng
  • Publication number: 20240255512
    Abstract: The present disclosure relates to a biomarker for diagnosis of oral cancer, using metabolite profiling and, more specifically, to a biomarker composition containing an acyl carnitine metabolite which varies in quantity upon the onset of oral cancer, and a diagnostic method for oral cancer, using same. The present disclosure allows for the early diagnosis of oral cancer which has been conventionally difficult to diagnose due to the impossible tissue biopsy thereof, and can reduce the pain and risk burden of patients because it uses a liquid biopsy method in which a blood sample is collected and analyzed.
    Type: Application
    Filed: May 31, 2022
    Publication date: August 1, 2024
    Applicants: NATIONAL CANCER CENTER, KOREA BASIC SCIENCE INSTITUTE
    Inventors: Mi Kyung KIM, Sung Weon CHOI, Geum Sook HWANG, Young Ae JUNG
  • Publication number: 20240254059
    Abstract: A system and method for steam curing and carbonation curing precast concrete, including: a steam curing tank forming a steam curing space; a carbonation curing tank disposed within the steam curing space and forming a carbonation curing space; a mold disposed within the carbonation curing space and forming a concrete shaping space by a plurality of segments; and a demolding device configured to separate the plurality of segments from one another to open the concrete shaping space.
    Type: Application
    Filed: December 21, 2023
    Publication date: August 1, 2024
    Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Haeng-Ki LEE, JiHoon PARK, Alam CHO, Naru KIM, DaeIk JANG
  • Publication number: 20240254397
    Abstract: A method for converting a fiber reinforced composite material into a softening or recycling agent or product for hard asphalt or bitumen may include contacting a fiber reinforced composite material with a solvent, and converting at least some of the fiber reinforced composite material into a liquid product. The softening step may include, contacting the hard asphalt with the liquid product to produce a softened or rejuvenated asphalt. The fiber reinforced composite material may include a solid organic thermoset material and fibers. The hard asphalt may be obtained by petroleum refining, polymer modification or field aging.
    Type: Application
    Filed: July 5, 2022
    Publication date: August 1, 2024
    Applicant: WESTERN RESEARCH INSTITUTE
    Inventors: Jeramie Joseph ADAMS, Jean-Pascal PLANCHE, Seth Taylor BASSHAM, Alex Mitchell LITERATI
  • Publication number: 20240258468
    Abstract: A phosphor which comprises a crystal phase that has a composition represented by the following formula [1]; and a light emitting device which is provided with this phosphor. (MA includes one or more elements selected from the group consisting of Ca, Ba, Na, K, Y, Gd, and La, MB includes one or more elements selected from the group consisting of Li, Mg, and Zn, MC includes one or more elements selected from the group consisting of Al, Si, Ga, In, and Sc, X includes one or more elements selected from the group consisting of F, Cl, Br, and I, Re includes one or more elements selected from the group consisting of Eu, Ce, Pr, Tb, and Dy, and a, b, c, d, e, f, x, and y respectively satisfy the following expressions. 0.8 ? a ? 1.2 1.4 ? b ? 2.6 1.4 ? c ? 2.6 1.1 ? d ? 2.9 1.1 ? e ? 2.9 0. ? f ? 0.1 0. < x ? 0.2 0. < y ? 0 .
    Type: Application
    Filed: April 4, 2024
    Publication date: August 1, 2024
    Applicants: MITSUBISHI CHEMICAL CORPORATION, NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Kyota UEDA, Yuhei INATA, Naoto HIROSAKI
  • Publication number: 20240258443
    Abstract: A light sensing device includes a semiconductor layer including a distributed Bragg reflector including a first surface of the semiconductor layer, and a photoelectric conversion unit including a second surface of the semiconductor layer, and the distributed Bragg reflector has a plurality of holes each having, in a cross-sectional view, a width gradually changing from a first width to a second width according to a width change period; a first electrode in one region of the semiconductor layer; and a second electrode on the second surface of the semiconductor layer and having a reflective metal.
    Type: Application
    Filed: April 9, 2024
    Publication date: August 1, 2024
    Applicants: Samsung Electronics Co., Ltd., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Insung JOE, Jonghwa SHIN, Joonkyo JUNG, Jong Uk KIM