Abstract: A use of Gemifibrozil and a pharmaceutically acceptable salt, ester, or stereoisomer thereof in the preparation of a medicament for the treatment and/or prevention of a neurodegenerative disease. The neurodegenerative disease is selected from Alzheimer's disease, Parkinson's disease, Huntington's disease, or amyotrophic lateral sclerosis. Further provided is a pharmaceutical composition for treating and/or preventing a neurodegenerative disease, wherein the pharmaceutical composition comprises Gemifibrozil, or a pharmaceutically acceptable salt, ester, or stereoisomer thereof, and, preferably, the pharmaceutical composition further comprises one or a plurality of pharmaceutically acceptable carriers. Further provided is a use of the pharmaceutical composition comprising Gemifibrozil, or a pharmaceutically acceptable salt, ester, or stereoisomer thereof in the preparation of a medicament for the treatment and/or prevention of a neurodegenerative disease.

Abstract: An electron emission device having a narrow electron energy range and excellent electron emitting efficiency, and an electron microscope using the electron emission device. An electron emission device having a laminated structure in which a first electrode, an electron accelerating layer made of an insulating film, and a second electrode are laminated in this order, in which the second electrode through which electrons transmit and from whose surface electrons emit, and the energy width of the emitted electrons is 100 meV or more and 600 meV or less. For example, graphene having one or more layers and 20 layers or less can be used as the second electrode, and hexagonal boron nitride can be used as the insulating film.

Abstract: A radio frequency (RF) aperture includes an interface board. An array of electrically conductive tapered projections have bases disposed on a front side of the interface printed circuit board and extend away from the front side of the interface printed circuit board. RF circuitry is disposed at the back side of the interface board and is electrically connected with the electrically conductive tapered projections.

Abstract: Provided is a preparing method of an amide directly from a tertiary amine by using a reduced titanium dioxide (Blue TiO2), which is formed by mixing a titanium dioxide having an anatase phase and a rutile phase with a reducing agent and selectively reducing any one of the anatase phase and the rutile phase, as a photocatalyst.

Abstract: Provided are positively charged nanoparticles and use thereof. According to the nanoparticles of an aspect, cucurbituril may limit electrostatic attraction between a guest for cucurbituril and a metal salt, thereby generating nanoparticles with a uniform size. Accordingly, the nanoparticles may have an effect of being capable of efficient intracellular gene delivery.

Abstract: A safety system for a heating apparatus includes an inlet for receiving input gases for combustion and a flue for expelling flue gases. A carbon monoxide sensor is also included for monitoring carbon monoxide content in the heating apparatus. The safety system also includes a pressure switch which permits the input gases to mix with the flue gases based on the information from the carbon monoxide sensor.

Abstract: A pressure difference generating apparatus includes a first pipe, a second pipe and a third pipe. The first pipe have a first inlet. The second pipe disposed inside of the first pipe has a conical inlet runner, a conical outlet runner and a neck portion between the conical inlet runner and outlet runner. The third pipe has a third conical outlet portion extending into the conical inlet runner. A first fluid and a second fluid flow into the first pipe and the third pipe separately in different flow rates. A negative pressure generated between the third conical outlet portion and the conical inlet runner allows at least part of the first fluid to flow into the conical inlet runner, then the neck portion, then the conical outlet runner, and finally out of the second pipe with the second fluid.

Abstract: The present disclosure provides a preparation method of a contact material with high thermal stability and low contact resistance based on an MgAgSb-based thermoelectric material and relates to the field of the contact materials preparation. The present disclosure aims to solve the problem of failure to achieve long-term stability for the MgAgSb/Mg3Bi2 device due to the fact that a contact material used by MgAgSb is Ag and MgAgSb may easily yield Ag3Sb in an Ag-rich environment at present. The method includes: at step 1, preparing MgCuSb nano-powder; at step 2, preparing MgCu0.1Ag0.87Sb0.99 nano-powder; at step 3, preparing MgCu0.1Ag0.87Sb0.99—Mg3.2Bi1.5Sb0.5 thermoelectric generation device. The present disclosure is applied to preparation of a contact material with high thermal stability and low contact resistance based on an MgAgSb-based thermoelectric material.

Abstract: A conical workpiece length measurement method is provided. Two laser displacement sensors are symmetrically arranged at opposite sides of a to-be-measured conical workpiece or a tooling loaded with the to-be-measured conical workpiece. Distance X0 from each displacement sensor to a bottom plane of the to-be-measured conical workpiece is calibrated. An elongated base plate is arranged at a tip of the to-be-measured conical workpiece, and the two displacement sensors measure their respective distances to the base plate. The total length of the to-be-measured conical workpiece is calculated as follows: X=X0+(X1+X2)/2, where X1 represents distance from one of the two displacement sensors to the base plate, and X2 represents distance from the other of the two displacement sensors to the base plate. Factors influencing the length measurement include calibration of the fixed length, measurement accuracy of the displacement sensor and a tilt error of the base plate.

Abstract: A method and apparatus for block propagation in a blockchain platform. Where multiple nodes establish a peer through a peer-to-peer network and maintain the same blockchain, a node stores information of a first peer transmitted a first forwarding message in a first storage when receiving, from the first peer, which is a node on the network, the first forwarding message including a first portion associated with a block. The node transmits a second forwarding message including the first portion to a second peer that is a node on the network. The node transmits a first request message to the first peer based on information in the first storage, the first request message requesting a second portion associated with the block and corresponding to the first portion. The node receives a third forwarding message including the second portion corresponding to the first request message from the first peer.

Abstract: A wireless communication terminal is disclosed. The wireless communication terminal includes a transceiver configured to transmit/receive a wireless signal; and a processor configured to control an operation of the wireless communication terminal. The transceiver transmits a training signal to a base wireless communication terminal based on a sub-frequency band allocated from the base wireless communication terminal, and transmits data to the base wireless communication terminal through the sub-frequency band allocated from the base wireless communication terminal. The training signal is used, by the base wireless communication terminal, for receiving the data from the wireless communication terminal.

Abstract: The subject matter disclosed herein is generally directed to novel CD8+ tumor infiltrating lymphocyte (TIL) subtypes associated with response to immunotherapy treatment. Specifically, the subtypes are associated with checkpoint blockade therapy. Moreover, the subject matter disclosed herein is generally directed to methods and compositions for use of the subtypes. Also, disclosed herein are gene signatures and markers associated with the subtypes and use of said signatures and markers. Further disclosed are therapeutic methods of using said gene signatures and immune cell subtypes. Further disclosed are pharmaceutical compositions comprising populations of CD8+ TILs enriched for a specific subtype.

Abstract: A flexible intestinal anastomosis stent which sucks secretions on an inner wall of an intestinal tract and at a suture site into a horn-shaped channel through a through-hole. The secretion is discharged to an inside of the stent body through a liquid-inlet hole after being squeezed by intestinal tract contents, thereby reducing a risk of infection at the suture site. A lower edge of the outlet end of the stent body has a concave polygonal structure, each reflex angle at a lower edge of the concave polygonal structure being formed with one inwardly folded wrinkle structure on a side wall of the stent body, and the wrinkle structure also able to accommodate the secretions. The lower edge is stressed and deformed by the intestinal tract contents to reduce a reflex angle, so that secretions in the wrinkle structure are discharged downwardly, such that risk of complications is reduced.

Abstract: The present invention relates to methods of treating an auditory disorder. In particular, the present invention relates to treating an auditory disorder using supraparticles comprising a therapeutic payload.

Abstract: Provided are topical delivery systems and methods for treating and/or preventing a disease or disorder in a subject, or for eliciting an immune response in a subject including applying, to at least a portion of the subject's post-auricular region, a topical delivery system including a therapeutically effective amount of a topical pharmaceutical composition comprising at least one active agent and a pharmaceutically acceptable carrier and/or adjuvant. The topical pharmaceutical composition can include a topical immunogenic composition. The topical delivery system can further include a flexible substrate in communication with the topical immunogenic composition. The subject can be a pediatric subject.

Abstract: Provided is a wireless communication terminal including a transceiver for transmitting/receiving a wireless signal and a processor for controlling an operation of the wireless communication terminal. The transceiver receives a first frame indicating information on a resource that a base wireless communication terminal allocates to a plurality of wireless communication terminals from the base wireless communication terminal, and transmits data to the base wireless communication terminal based on the first frame. The plurality of wireless communication terminals include the wireless communication terminal.

Abstract: Disclosed are a voltage source converter based high voltage direct current (VSC-HVDC) high-frequency resonance suppression method, system, and device. The method includes: when an effective value of an actually input alternating current (AC) voltage is reduced from a normal value to meet a preset condition, making the virtual electrical quantity completely equal to the actual electrical quantity, and performing full real-time tracking for the actual electrical quantity to improve dynamic characteristics of a power system at the moment of a fault; and after performing the full tracking for a period of time, if the effective value of the actual AC voltage is less than a preset threshold, performing adaptive tracking until the actual electrical quantity recovers to a stable value. The present disclosure can reduce a risk of high-frequency resonance of a VSC-HVDC, avoid deteriorating dynamic characteristics of the VSC-HVDC, and improve safety of fault ride-through of the VSC-HVDC.

Abstract: The present disclosure provides vermicompost made of aquatic plants and a preparation method of the vermicompost. The preparation method includes: mixing aquatic plant residues and fresh cow dung according to a proportion, and crushing the aquatic plant residues while stirring until even mixing; adding earthworms to a mixture of the aquatic plant residues and the cow dung, where the earthworms transform the mixture of the aquatic plant residues and the cow dung in a forest at 15-35° C., and moisture in the mixture is maintained at 65-75% in the process; and after 35-45 days, separating the earthworms and vermicompost, and drying the vermicompost to obtain the vermicompost made of aquatic plants.

Abstract: The present invention relates to a pharmaceutical composition which is for preventing or treating obesity, and comprises a biglycan as an active ingredient. Biglycan according to the present invention suppresses appetite by decreasing the expression of Agrp and NPY, which are appetite promoting peptides, and increasing the expression of POMC, which is an appetite suppressing peptide, and thus is very useful as a medicine for treating obesity.

Abstract: The present disclosure relates to an aglycosylated antibody-producing transgenic mouse and the use of an aglycosylated antibody produced therefrom. When the transgenic mouse of the present disclosure is used, it is possible to easily produce aglycosylated antibodies against various target antigens, and to precisely diagnose disease by detecting a glycoprotein biomarker using the produced aglycosylated antibody.