Abstract: A method of treating a waste evacuation dysfunction comprising administering transcutaneous electrical stimulation (TES) to at least one lower pelvic and/or sacral region for a specific treatment regimens. Also disclosed is a system for configuring a stimulation device to deliver transcutaneous electrical stimulation (TES) the system comprising: a computing device storing or having access to a plurality or TES settings and comprising a user interface to enable authorized selection of at least on of the TES settings for provision of TES by the stimulation device according to the at least one selected TES setting and the stimulation device communicatively coupled to the computing device to receive and store the selected at least one TES setting the stimulation device being of a size to be readily carried on a body and configured to selectively provide current to external electrode according to the one TES setting.

Abstract: Disclosed is a laser radar apparatus. The laser radar apparatus includes: a light transmission unit configured to output a laser pulse by using a light source; a light reception unit configured to receive a reflected laser pulse in connection with the laser pulse; and a controller configured to adjust a repetition rate of the laser pulse of the light source, in which the controller adjusts the repetition rate of the laser pulse based on at least one of reception power, a target distance, a movement speed, a vertical angle, and a radiation angle.

Abstract: A natural gas hydrate drilling simulation device, includes a hydrate rock core simulation system, a drilling system, a drilling fluid injection system and a drilling fluid treatment system. The hydrate rock core simulation system includes a hydrate formation simulation wellbore, an artificial rock core, a water bath jacket and low temperature water bath. The drilling system includes a bracket, a high pressure rotary connecting device, a hydraulic device and a drilling device. The drilling fluid injection system includes a mud tank, a drilling fluid flowmeter, mud pumps and an overflow valve. The drilling fluid treatment system includes a high pressure sand remover, a back pressure and overflow control system, a gas-liquid separator, a dyer, a gas flowmeter, a liquid flowmeter and a mud treatment tank. This natural gas hydrate drilling simulation device performs simulation experiments under a variety of downhole working condition environments.

Abstract: Disclosed herein is a novel strontium precursor containing a beta-diketonate compound. Being superior in thermal stability and volatility, the strontium precursor can form a quality strontium thin film.

Abstract: A programmable photonic integrated circuit implements arbitrary linear optics transformations in the spatial mode basis with high fidelity. Under a realistic fabrication model, we analyze programmed implementations of the CNOT gate, CPHASE gate, iterative phase estimation algorithm, state preparation, and quantum random walks. We find that programmability dramatically improves device tolerance to fabrication imperfections and enables a single device to implement a broad range of both quantum and classical linear optics experiments. Our results suggest that existing fabrication processes are sufficient to build such a device in the silicon photonics platform.

Abstract: A liquid-crystal photo-alignment layer that is composed of polymer stabilized azo dyes is provided, where a polymer network is introduced in the photo-alignment layer for stabilization. The photo-alignment layer is realized based on a two-step irradiation to first achieve molecule alignment to form the photo-alignment layer and then stabilize this layer. To realize the photo-alignment layer, a pre-determined surface of the substrate is first coated with a film of mixture. The mixture comprises an azo dye and a monomer preferably mixed in an optimal concentration of 0.67 wt/wt. The azo dye and the monomer have light-absorption peaks at different wavelengths such that photo-alignment of the azo-dye molecules and stabilization of the photo-alignment layer by polymerization of the monomer are achievable by two separate exposures of light to the film.

Abstract: Disclosed is a boron recovering device including: an aeration-type water-channel reactor including a water channel; at least one aeration unit disposed in the water channel and aerating a boron-containing solution by passing it through the water channel to deposit boron in the form of borax; and a precipitation bath precipitating the deposited borax in the boron-containing solution having passed through the aeration-type water-channel reactor and separating a filtrate by overflowing, a boron recovering device, a method of recovering boron, and a boron recovering system.

Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and pharmaceutical compositions thereof. The present invention also provides methods and kits using the inventive compounds and pharmaceutical compositions for treating and/or preventing diseases associated with protein aggregation, such as amyloidoses (e.g., Parkinson's disease and Alzheimer's disease), treating and/or preventing neurodegenerative diseases, treating and/or preventing diseases associated with Tar DNA binding protein 43 kDa, reducing or preventing protein aggregation, and/or modulating E3 ubiquitin ligase in a subject in need thereof.

Abstract: The invention provides methods, reagents and systems for incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to enrich the proteins or fragments thereof in a number of uses, such as proteomic analysis, imaging of diseased tissues/cells, etc.

Abstract: Disclosed are an apparatus and method for generating a scenario for testing interoperability of robot software. The apparatus for generating a scenario for testing interoperability of robot software includes a user interface unit for receiving a request to test a component under test from a user, a semantic model-mapping unit for mapping a test case semantic model to the component under test, a test scenario template selection unit for selecting a test scenario template corresponding to a type of the component under test, a test case component selection unit for selecting a test case component based on whether the mapped test case semantic model corresponds to a source or a target, and an interoperability test scenario generation unit for generating an interoperability test scenario based on information about a connection between the component under test and the test case component in the selected test scenario template.

Abstract: Provided is a method of improving a bandwidth of an antenna using a transmission line stub to enable long-range communication together with broadband matching. According to the method, it is possible to combine a transmission line stub in series or parallel with a feeding point, which is an antenna signal input/output point of a body serving as an antenna, and apply the transmission line stub to an antenna for wide use.

Abstract: Provided is a scanning device including a transmission module configured to divide a scan target into a plurality of scan areas and alternately irradiate a first laser light and a second laser light to the scan areas that are sequentially arranged, a reception module configured to receive laser lights reflected from each of the scan areas, and an image generation module configured to generate divided images of each of the scan areas by using the reflected laser lights and generate a whole image of the scan target based on the divided images and an edge component of the reflected laser lights, wherein the transmission module is configured to trigger a rising edge of a trigger signal to generate the first laser light and trigger a falling edge of the trigger signal to generate the second laser light.

Abstract: A repeat expansion in C90RF72 causes frontotemporal dementia and amyotrophic lateral sclerosis (c9FTD/ALS). RNA of the expanded repeat (r(GGGGCC)exp) forms nuclear foci or undergoes repeat-associated non-ATG (RAN) translation producing “c9RAN proteins”. Since neutralizing r(GGGGCC)exp could inhibit these potentially toxic events, we sought to identify small molecule binders of r(GGGGCC)exp, Chemical and enzymatic probing of r(GGGGCC)8 indicate it adopts a hairpin structure in equilibrium with a quadruplex structure, Using this model, bioactive small molecules targeting r(GGGGCC)exp were designed arid found to significantly inhibit RAN translation and foci formation in cultured cells expressing r(GGGGCC)66 and neurons trans-differentiated from fibroblasts of repeat expansion carriers. Finally, we show that poly(GP) c9RAN proteins are specifically detected in c9ALS patient cerebrospinal fluid.

Abstract: A positioning system by visible light includes at least one luminaire, at least one positioning transceiver and a server. The luminaire is disposed at a specific position and has a first identification code, and emits the first identification code in a selected signal form. Each positioning transceiver has a second identification code, and further includes a receiving device and a wireless transceiver. The receiving device movably receives the first identification and demodulates the first identification code. The wireless transceiver transmits the first and the second identification codes to a receiving terminal. The server is coupled to the at least one positioning transceiver via the receiving terminal, and obtains the first and the second identification codes so as to position the at least one positioning transceiver in a space defined by the at least one luminaire.

Abstract: A hole transporting material having excellent heat resistance and durability, a perovskite solar cell including the hole transporting material in a hole transporting layer, and a method for manufacturing the solar cell are provided. Provided is a perovskite solar cell having PCE which is equal to or greater than PCE in the related art because the hole transporting layer is formed by using the hole transporting material in which the phthalocyanine-based organic ligand is coordinate-bonded to metal. Also, provided is a perovskite solar cell which can maintain initial PCE for a long time in a wide temperature range when the hole transporting material is used as the hole transporting layer due to excellent heat resistance and durability.

Abstract: A microfluidic system for cell retention for a perfusion bioreactor is provided. The system comprises at least one inlet configured to receive a bioreaction mixture to be processed. At least one curvilinear microchannel is in fluid flow connection with the at least one inlet, the at least one curvilinear microchannel being adapted to isolate cells in the bioreaction mixture, based on cell size, along at least one portion of a cross-section of the at least one curvilinear microchannel. At least two outlets are in fluid flow connection with the at least one curvilinear microchannel. At least one outlet of the at least two outlets is configured to flow the isolated cells to be recycled to the perfusion bioreactor.

Abstract: A preparation method of separation membrane is provided. First, a polyimide composition including a dissolvable polyimide, a crosslinking agent, and a solvent is provided. The dissolvable polyimide is represented by formula 1: wherein B is a tetravalent organic group derived from a tetracarboxylic dianhydride containing aromatic group, A is a divalent organic group derived from a diamine containing aromatic group, A? is a divalent organic group derived from a diamine containing aromatic group and carboxylic acid group, and 0.1?X?0.9. The crosslinking agent is an aziridine crosslinking agent, an isocyanate crosslinking agent, an epoxy crosslinking agent, a diamine crosslinking agent, or a triamine crosslinking agent. A crosslinking process is performed on the polyimide composition. The polyimide composition which has been subjected to the crosslinking process is coated on a substrate to form a polyimide membrane. A dry phase inversion process is performed on the polyimide membrane.

Abstract: The present disclosure provides FGF2 mutant proteins, such as those having an N-terminal deletion, point mutation(s), or combinations thereof, which can reduce blood glucose in a mammal. Thus, the disclosed mutant FGF2 proteins can be used to treat one or more metabolic diseases. In some examples, mutant FGF2 proteins have reduced mitogenic activity. Also provided are nucleic acid molecules that encode such proteins, and vectors and cells that include such nucleic acids. Methods of using the disclosed molecules to reduce blood glucose levels, for example to treat a metabolic disorder are also provided.

Abstract: In a position estimation of a terminal using a beacon, the precision is improved by reducing influences of noise due to moving obstacles such as human so that a beacon region can be easily and flexibly constituted. According to a typical embodiment, a portable terminal includes a location determination unit that acquires beacon information including a reception intensity of each of beacon signals received from one or more of the beacon terminals, accumulates history data as beacon detection information, acquires a plurality of pieces of the beacon information accumulated as the beacon detection information and contained within a past predetermined period at every predetermined interval, aggregates the beacon information by scoring, and determines the beacon terminal located most closely based upon scores.

Abstract: The disclosure is directed to a device to device (D2D) mobility management method applicable to a network entity and a user equipment and related apparatuses. In one of the exemplary embodiments, the disclosure is directed to a device to device (D2D) mobility management method used by a network entity. The method would include not limited to transmitting a service request message which includes an application identifier (ID) and a traffic type ID, receiving a first measurement report including a signal quality measurement which is measured based on the service request message, determining a topology type ID and a communication type ID in response to receiving the first measurement report, transmit an access request message which comprises the topology type ID, the communication type ID, and the traffic type ID, and receive an authorization of a network slice in response to transmitting the access request message.