Abstract: The present invention provides an aqueous tumor-targeting liposome nanoparticle composition comprising an aqueous dispersion of liposome nanoparticles. The nanoparticles preferably encapsulate an anti-cancer chemotherapeutic agent, which can be added to a pre-formed liposome composition or can be incorporated in the liposomes during the formation of the liposomes. The liposome nanoparticles comprise a legumain-targeting lipid admixed with one or more other micelle or vesicle-forming lipid materials in the form of nanoparticulate liposomes dispersed in an aqueous carrier. A preferred tumor-targeting liposome nanoparticle composition comprises (a) a legumain-targeting lipid component, (b) a zwitterionic lipid component; (c) an amino-substituted lipid component; (d) a neutral lipid component; and (e) polyethylene glycol-conjugated lipid component. The legumain-targeting lipid component comprising a hydrophobic lipid portion covalenetly attached to a legumain-binding moiety.

Abstract: The present invention provides, among other things, methods of delivering mRNA in vivo, including administering to a subject in need of delivery a composition comprising an mRNA encoding a protein, encapsulated within a liposome such that the administering of the composition results in the expression of the protein encoded by the mRNA in vivo, wherein the liposome comprises a cationic lipid of formula I-c: or a pharmaceutically acceptable salt thereof.

Abstract: The subject matter relates to newly discovered nucleic acid molecules and proteins associated with thymic lymphoma and hamartomatous tumors. Compositions and methods for detecting, characterizing, preventing, and treating human thymic lymphoma and hamartomatous tumors are provided.

Abstract: An ultra-wideband tapered slot antenna that is capable of providing spatial independent band-stop characteristics which are irrelevant to the radiation direction of the antenna in a dual-stop band. The antenna includes an ultra-wideband tapered slot antenna includes a radiating unit formed on a first surface of a substrate and configured to radiate radio signals. A feeding unit is formed on a second surface of the substrate and is configured to provide the radio signals to the radiating unit. Separate stubs are formed to be spaced apart from the feeding unit around the feeding unit and are configured to reject frequencies in a first stop band from the radio signals radiated from the radiating unit. A slot is formed in a stub formed at a first end of the feeding unit and is configured to reject frequencies in a second stop band from the radio signals.

Abstract: The present invention provides soluble single wall nanotube (SWNT) constructs functionalized with a plurality of a targeting moiety and a plurality of one or more payload molecules attached thereto. The targeting moiety and the payload molecules may be attached to the soluble SWNT via a DNA or other oligomer platform attached to the SWNT. These soluble SWNT constructs may comprise a radionuclide or contrast agent and as such are effective as diagnostic and therapeutic agents. Methods provided herein are to diagnosing or locating a cancer, treating a cancer, eliciting an immune response against a cancer or delivering an anticancer drug in situ via an enzymatic nanofactory using the soluble SWNT constructs.

Abstract: Methods for imaging a tumor in an animal including labeling an organ in the animal with a first detectable label detectable by both fluorescence molecular tomography (FMT) and magnetic resonance (MR) and localized substantially exclusively to the organ, whereupon the labeled organ is capable of use as a first fiducial marker in an image of the animal; administering to the animal a detectably labeled probe that localizes substantially exclusively to a region of interest in the body of the animal; after labeling the organ and administering the detectably labeled probe, imaging the animal with a FMT imager to generate an FMT image, and imaging the animal with a MR imager to generate an MR image; and aligning the FMT and MR images using the first fiducial marker as a first reference point, thereby generating an image comprising a fusion of the FMT image and the MR image.

Abstract: A method in a data processing system and apparatus for organizing files, data items, web site members, or web pages, structured or unstructured, of multiple users stored across one or more server computers into hierarchical file structures on a recordable medium of a data processing system. A user-defined metalabel is assigned to each of the electronic files, data items, web site members, or web pages. The electronic files, data items, web site members, or web pages are organized as a function of the metalabels into the hierarchical file structures. The method includes automatically forming personalized hierarchies, such as a shadow copy for a second user, from the user-defined metalabels of a first user according to a user profile. The method includes automatically forming keywords of strings of at least two user-defined metalabels or a portion thereof, and automatically forming search structures of the keywords existing simultaneously with the plurality of hierarchical structures.

Abstract: The present invention relates to isolated human cells that are precursors of endothelial cells other than embryonic stem cells, to isolated murine cells that are precursors of endothelial cells, and to methods using same. In particular, the present invention relates to established cell lines of isolated human cells that are precursors of endothelial cells other than embryonic stem cells and established cell lines of isolated murine cells that are precursors of endothelial cells. The present invention can be used in particular in the medical and/or veterinary fields, in particular in the field of therapeutics and/or in the field of studies of cellular mechanisms.

Abstract: A magnetic suspension planar motor comprises a structure of superconductor excitation. A primary base plate is in a shape of board. Armature windings are fixed on an air gap side of the primary base plate. A secondary base plate in a secondary structure is evenly divided into 2 h*2 h magnet cells. 2 h2 superconducting magnets are respectively fixed in the magnet cells on the secondary base plate, which resembles a checkerboard pattern. The superconducting magnets are adjacent to each other, neither in a horizontal direction nor in a vertical direction. The superconducting magnets are magnetized parallelly, and magnetization directions of the superconducting magnets are perpendicular to a surface on an air gap side of the secondary base plate. The superconducting magnets in a same row or column have same magnetization directions, and the superconducting magnets in adjacent rows columns have contrary magnetization directions. A cooling container shields all of the superconducting magnets.

Abstract: Provided is a method for fabricating an electronic device, the method including: preparing a carrier substrate including an element region and a wiring region; forming a sacrificial layer on the carrier substrate; forming an electronic element on the sacrificial layer of the element region; forming a first elastic layer having a corrugated surface on the first elastic layer of the wiring region; forming a metal wirings electrically connecting the electronic element thereto, on the first elastic layer of the wiring region; forming a second elastic layer covering the metal wirings, on the first elastic layer; forming a high rigidity pattern filling in a recess of the second elastic layer above the electronic element so as to overlap the electronic element, and having a corrugated surface; forming a third elastic layer on the second elastic layer and the high rigidity pattern; and separating the carrier substrate.

Abstract: A method and a device for encoding/decoding images are disclosed. The method for encoding images comprises the steps of: deriving a scan type of a residual signal for a current block according to whether or not the current block is a transform skip block; and applying the scan type to the residual signal for the current block, wherein the transform skip block is a block to which transform for the current block is not applied and is specified on the basis of information indicating whether or not transform for the current block is to be applied.

Abstract: A gas condensing device may be configured to condense regeneration gas and separate target gas from condensate. The gas condensing device may include: a housing; a condenser mounted in an upper portion of the housing and configured to condense the regeneration gas; and a reflux apparatus mounted in the housing below the condenser and configured to temporarily store the condensate and discharge evaporation gas evaporated from the condensate back to the condenser.

Abstract: A method for analyzing fMRI brain data, comprising: collecting the fMRI data including spatial information and temporal information from subjects; preprocessing the fMRI data; computing independent components (ICs) and their corresponding time course for each individual subjects; constructing an initial functional connectivity pattern; constructing a classifier based on the functional connectivity pattern; and applying the classifier to functional connectivity patterns of individual subjects for statistical analysis or diagnosis. The method may be used in fMRI based studies of a brain function and brain disorder diagnosis.

Abstract: The present disclosure relates to immunoglobulins and immunoglobulin conjugates with reduced oligomerization and efficient labeling and compositions, methods of generating such immunoglobulins and immunoglobulin conjugates and methods of using such immunoglobulin conjugates particularly in the treatment and prevention of disease.

Abstract: A CDDP complex is formed by complexation of CDDP and a polymer having a structure of Formula (I). The CDDP complex has good biocompatibility and is degradable. A side chain of the polymer is grafted with polyethylene glycol, which gives the CDDP complex good dissolvability. When dissolved in an aqueous medium, the CDDP is protected by a hydrophilic polyethylene glycol chain segment and a hydrophobic amino acid chain segment, which can effectively avoid a sudden release of the CDDP due to the influence of the blood circulation system after intravenous injection, thus improving the stability of the CDDP complex. A carboxyl group contained in the CDDP complex has pH value sensitivity and tends to be deprotonated in a low pH environment, which is advantageous for promoting the release of a drug, and improving the efficiency of the drug.

Abstract: Provided is an image recognition apparatus that identifies a person through a face of the person recognized from a photographed image, an image recognition method thereof and a face image generation method thereof. The method for recognizing a face image includes generating candidate images including at least one morphable image which is generated using an object image, extracting first features from the generated candidate images, extracting second feature from a reference image, and generating at least one score corresponding to each of the at least one morphable image by comparing the first features with the second feature, and performing matching to calculate a final score from the generated at least one score.

Abstract: Provided are a titanium dioxide-coated upconverting nanoparticle (UCNP) and a photocatalyst complex containing a gold nanorod (GNR) combined with the titanium dioxide-coated UCNP.

Abstract: A method is provided for fabricating a catalyst carrier. At first, aluminum hydroxide is used for forming an alumina powder. The alumina powder is mixed with carbon nanotubes and a complex additive to be shaped into a cake. The cake is kneaded into a noodle-like shape to be hot-dried. Then, calcination is processed in a furnace under 1200 celsius degrees (° C.) with air passed through. The crystal structure remains without phase change. A catalyst carrier of ?-alumina having nano-scaled pores is formed. The catalyst carrier is a powdery material made into different three-dimensional forms. The catalyst carrier thus fabricated is suitable for generating hydrogen through methane reformation. The catalyst carrier has a methane conversion greater than 99 percents. The catalyst carrier will not be crumbled under 800° C. for 4000 hours without carbon deposit.

Abstract: This disclosure describes methods, systems, computer-readable media, and apparatuses for efficiently calculating group-by statistics. A data set that includes multiple entries is accessed. The multiple entries are grouped into group-by subsets which are formed on two or more group-by variables and which are subsets are subsets of the data set. Cardinality data is determined for each of the group-by subsets, wherein cardinality data represents a number of entries in a group-by subset. At least one summary of data in each of the group-by subsets is generated, wherein each of the summaries includes the cardinality data determined for the group-by subset. Objects for the group-by subsets are initialized such that the objects store the summaries. The objects may then be used to generate multiple statistical summaries of the data set.

Abstract: Diagnosing or treating a human ear includes transporting a conjugated nanoparticle or a magnetically responsive nanoparticle into a human's middle or inner ear. Otologic nanophoresis includes electrically, magnetically or electromagnetically driving a nanoparticle through a membrane of the ear, including a tympanic membrane, a round window membrane, an oval window membrane, or a circulatory membrane. An otologic diagnostic device includes a nanoparticle conjugated with a material selected from the group consisting of lipids, proteins, growth factors, growth hormones, antioxidants, free radical scavengers, steroid preparations, and metabolically active substances; an otologic therapeutic device includes the same categories of substances and chemotherapeutic drugs. Another otologic composition includes a nanoparticle conjugated with a substance perceptible to magnetic resonance imaging.