Patents Assigned to INSTITUTE
  • Patent number: 9518035
    Abstract: A method for preparing glycidol using glycerol includes mixing glycerol with urea in the presence of at least one zinc-based catalyst selected from the group consisting of Zn(NO3)2, ZnCl2, ZnO and Zn(OAc)2 under a pressure of 0.5-10 kPa at a temperature of 100-170° C. to obtain glycerol carbonate; filtering the glycerol carbonate mixed with the zinc-based catalyst through an adsorbent including a polymer resin coordinated with amine groups to separate the zinc-based catalyst and glycerol carbonate from each other; and carrying out reaction of the glycerol carbonate separated from the zinc-based catalyst in the presence of an anion alkali metal salt catalyst that is Na, K, Rb, Cs or a mixture thereof containing at least one anion selected from the group consisting of Cl?, Br?, I?, NO3?, NO2? and acetate under a pressure of 0.13-6.67 kPa at a temperature of 140-250° C. to obtain glycidol.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: December 13, 2016
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Joo Lee, Byoung Sung Ahn, Sang Deuk Lee, Ji Sik Choi, Hyejeong Lee, Hye Jin Lee
  • Patent number: 9518099
    Abstract: Disclosed are a folded chlorotoxin, a chlorotoxin variant and a folded chlorotoxin variant and their preparation technology. The folded chlorotoxin has a peptide sequence of MCMPCFTTDHQMARKCDDCCGGKGRGKCYGPQCLCR-NH2, and the folded chlorotoxin variant has a peptide sequence of MCMPCFTTDHQMARSCDDCCGGSGRGSCYGPQCLCR-NH2 and is formed by replacing serine (Ser, S) by lysine (Lys, K) in the peptide sequence of chlorotoxin. The chlorotoxin and its derivatives have potential application values in biological and medical fields and good economic and social benefits to life, health, and personalized healthcare.
    Type: Grant
    Filed: September 13, 2015
    Date of Patent: December 13, 2016
    Assignee: WENZHOU INSTITUTE OF BIOMATERIALS AND ENGINEERING
    Inventor: Zhe Liu
  • Patent number: 9517879
    Abstract: A foldable transport container substantially slides and folds so that the transport container can be folded and unfolded conveniently. In an example embodiment, a foldable transport container comprises a planar foldable base, a pair of opposing straight side walls, a pair opposing foldable end walls, a foldable top, and a folding mechanism. A first straight side wall is operable to slide towards a second straight side wall along a first longitudinal axis, and a first foldable end wall and a second foldable end wall are operable to fold inwardly towards each other along a second latitudinal axis. The folding mechanism allows surfaces of the first and second foldable base sections to be used for storing goods within the container without any interfering protrusions when the foldable transport container is in its erected configuration.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: December 13, 2016
    Assignees: Indian Institute of Technology, Simpri Investments Limited
    Inventors: Anoop Chawla, Sudipto Mukherjee
  • Patent number: 9519975
    Abstract: A method of determining an edge of an object on a digital image sequence comprising the step of determining a first gradient direction profile of a first image in the digital image sequence; determining a second gradient direction profile of a second image in the digital image sequence; computing a differential profile based on the first gradient direction profile and the second gradient direction profile; and determining the edge of the object based on the differential profile wherein the differential profile registers gradient magnitudes of the second gradient direction profile and angular differences between the first gradient direction profile and the second gradient direction profile. A system thereof is also disclosed.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: December 13, 2016
    Assignee: Hong Kong Applied Science and Technology Research Institute Co. Ltd.
    Inventor: Yan Wang
  • Patent number: 9518014
    Abstract: A process for the production of ezetimibe and intermediates used in said process are disclosed. A kind of Morita-Baylis-Hillman adduct can be altered to chiral carboxylic acid derivatives of ?-arylamino ?-methylene with high activity and selectivity by means of ally lamination reaction, and the above carboxylic acid derivatives of ?-arylamino ?-methylene can be altered to the chiral intermediates of ezetimibe by means of simple conversion and further synthesized into the chiral drug ezetimibe. The synthesis route introduces chirality through the use of a chiral catalysis method, thereby avoiding the use of the chiral auxiliary oxazolidinone; and the route is economical and eco-friendly.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: December 13, 2016
    Assignee: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
    Inventors: Kuiling Ding, Xiaoming Wang, Zheng Wang
  • Patent number: 9518300
    Abstract: Provided are compositions and methods for treating hematological malignancies, such as multiple myeloma, in a subject by increasing levels or activity of miR-30 RNA in plasma cells of the subject.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: December 13, 2016
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Ruben Carrasco, Jianjun Zhao
  • Patent number: 9520243
    Abstract: Disclosed are a method of manufacturing a flexible thin-film type super-capacitor device and a super-capacitor device manufactured by the same. The flexible thin-film type super-capacitor device comprises a base film which has flexibility; a separator which is interposed between the base films; and an active material which is formed on the base film. Thus, flexibility is given since thickness is very thin while maintaining high electrical conductivity and high binding property. In addition, economic feasibility is high and mass production is possible. Further, it is possible to stably and efficiently contain a highly corrosive material.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: December 13, 2016
    Assignee: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Jung-Joon Yoo, Jong-Huy Kim, Jae-Kook Yoon, Hana Yoon, Yong-Il Kim
  • Publication number: 20160354458
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Application
    Filed: February 11, 2015
    Publication date: December 8, 2016
    Applicants: The State of Israel, Ministry of Agriculture & Rur al Development, Kimron Veterinary Institute, Ramot at Tel-Aviv University Ltd.
    Inventors: Eran Bacharach, Avi Eldar
  • Publication number: 20160356728
    Abstract: Apparatus for improving a three-dimensional (3D) reconstruction of a sample is programmed to execute instructions including: removing uncorrelated noise in said 3D reconstruction with COMET or other regularization techniques; and removing correlated noise in said 3D reconstruction by applying an Extended Field Iterative Reconstruction Technique (EFIRT) procedure.
    Type: Application
    Filed: July 21, 2016
    Publication date: December 8, 2016
    Applicant: Okinawa Institute of Science and Technology School Corporation
    Inventors: Faisal MAHMOOD, Lars-Göran Wallentin ÖFVERSTEDT, Bo Ulf SKOGLUND
  • Publication number: 20160355720
    Abstract: The present disclosure relates to a thermal storage material containing a hexanary composition of NaNO3—NaNO2—KNO3—KNO2—Ca(NO3)2—LiNO3 for lowering a melting point of molten salts.
    Type: Application
    Filed: November 12, 2014
    Publication date: December 8, 2016
    Applicant: Korea Institute of Energy Research
    Inventors: Hong-Soo Kim, Si-Kyoung Kim, Kang Bai, Jong-Kyu Kim, Yong-Heack Kang
  • Publication number: 20160354406
    Abstract: An absorbable periodontal tissue and bone regeneration material uses bacterial cellulose that has been exposed to radiation. The bacterial cellulose was confirmed to block the invasion of soft tissue in a calvarial defect in rat and rabbit models and to display excellent absorptiveness enough to contribute bone formation. Therefore, the bacterial cellulose can be developed as an absorbable periodontal tissue and bone regeneration material useful in the field of medical engineering by regulating biodegradability without using chemicals that are toxic to human and environment.
    Type: Application
    Filed: April 13, 2016
    Publication date: December 8, 2016
    Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTE
    Inventors: Youn-Mook Lim, Sung In Jeong, Hui-Jeong Gwon, Jong Seok Park, Jung-Bo Huh
  • Publication number: 20160360207
    Abstract: A method of encoding or decoding coding units of a video content in a palette coding mode using an adaptive palette predictor is provided. The method includes adaptively determining a maximum size of the adaptive palette predictor based on at least one of a complexity of the video content and coding quality of the video content; and encoding or decoding the coding units of the video content in the palette coding mode using the adaptive palette predictor while limiting the adaptive palette predictor that is derived from all palette(s) of previously encoded or decoded coding unit(s) of the video content within the maximum size determined in the adaptively determining step. An apparatus of encoding or decoding coding units of a video content in a palette coding mode using an adaptive palette predictor is also provided.
    Type: Application
    Filed: June 8, 2016
    Publication date: December 8, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Ching-Chieh LIN, Yao-Jen CHANG, Chun-Lung LIN, Jih-Sheng TU
  • Publication number: 20160354440
    Abstract: The method provides methods and compositions for treating metabolic disorders such as impaired glucose tolerance, elevated blood glucose, insulin resistance, dyslipidemia, obesity, and fatty liver.
    Type: Application
    Filed: August 18, 2016
    Publication date: December 8, 2016
    Applicant: Salk Institute for Biological Studies
    Inventors: Johan W. Jonker, Michael Downes, Ronald M. Evans, Jae Myoung Suh
  • Publication number: 20160356923
    Abstract: The invention provides a class of block copolymers having a plurality of chemically different blocks, at least a portion of which incorporating polymer side chain groups having a helical secondary structure. The invention also provides structures generated by self-assembly of polymer blends including at least one block copolymer component, such as a brush block polymer or wedge-type block polymer. The invention provides, for example, periodic nanostructures and microstructures generated by self-assembly of block copolymers and polymer blends comprising a mixture of at least one block copolymer component, such as a brush block copolymer, and at least a second component.
    Type: Application
    Filed: August 22, 2016
    Publication date: December 8, 2016
    Applicant: California Institute of Technology
    Inventors: Garret M. MIYAKE, Raymond WEITEKAMP, Robert H. GRUBBS, Victoria PIUNOVA
  • Publication number: 20160355849
    Abstract: Aspects of the invention relate to methods for producing lactic acid from organic waste, comprising contacting organic waste with a microbial community to form a fermentation mixture, and fermenting the fermentation mixture under controlled pH and temperature conditions for a time sufficient to produce lactic acid.
    Type: Application
    Filed: April 29, 2016
    Publication date: December 8, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Devin Hedley Currie, Kristen Jean Fortnam
  • Publication number: 20160355473
    Abstract: The present invention relates to the novel compounds represented by Formula (Ia) or (Ib) and to their pharmaceutical preparations for the treatment of atherosclerosis and cholesterol level reduction.
    Type: Application
    Filed: December 16, 2014
    Publication date: December 8, 2016
    Applicant: Rudjer Boskovic Institute
    Inventors: Ivan Habus, Tonko Drazic
  • Publication number: 20160360529
    Abstract: A base station defines a short TTI (transmission time interval) equal to the length of one subslot as the minimum unit of a time resource for data transmission in a subframe including a plurality of subslots, determines the RS type the terminal will use for transmission, among a plurality of RS types, based on the positions of RSs (reference signals) within the short TTI, and sends information on the RS type the terminal will use for transmission to the terminal.
    Type: Application
    Filed: June 4, 2016
    Publication date: December 8, 2016
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Yu Ro LEE, Kwang Jae LIM, Won-Ik KIM, Taegyun NOH, Sung Cheol CHANG
  • Publication number: 20160360229
    Abstract: Disclosed are a method for inducing a prediction motion vector and an apparatus using the same. An image decoding method can include: a step of determining the information related to a plurality of spatial candidate prediction motion vectors from peripheral predicted blocks of a predicted target block; and a step of determining the information related to temporal candidate prediction motion vectors on the basis of the information related to the plurality of spatial candidate prediction motion vectors. Accordingly, the present invention can reduce complexity and can enhance coding efficiency when inducing the optimum prediction motion vector.
    Type: Application
    Filed: August 23, 2016
    Publication date: December 8, 2016
    Applicants: Electronics and Telecommunications Research Institute, Industry-University Cooperation Foundation Korea Aerospace University
    Inventors: Sung Chang LIM, Hui Yong KIM, Jin Ho LEE, Jin Soo CHOI, Jin Woong KIM, Jae Gon KIM, Sang Yong LEE, Un Ki PARK
  • Publication number: 20160359606
    Abstract: Provided is a communication method in a wireless communication system using an interference alignment. The method includes: receiving, by a first AP, a data stream by using N1 (natural number) first reception antennas, and receiving, by a second AP, the data stream by using N2 (natural number) second reception antennas, in a wireless communication system including the first AP and the second AP which receive the data stream through a transmission beam which one or more user terminals having m (natural number) transmission antennas within a given number transmit; and updating to selectively add a part of user terminals which are newly connected to the first AP and the second AP to a set of connected user terminal, and transmitting, by each terminal of the set of connected user terminal, linearly independent transmission beams by applying an interference alignment with respect to a plurality of the first and the second reception antennas for the updated set of connected user terminal.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 8, 2016
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jin Hyung OH, Sang Woon JEON, Myung Sun SONG
  • Publication number: 20160357903
    Abstract: Current methods for annotating and interpreting human genetic variation typically exploit only a single information type (e.g., conservation) and/or are restricted in scope (e.g., to missense changes). Here, a method for objectively integrating many diverse annotations into a single measure (integrated deleteriousness score, or C-score) for each variant is described. The method may be implemented as a support vector machine (SVM) trained to differentiate high-frequency human-derived alleles from simulated variants. C-scores were precomputed for all 8.6 billion possible human single-nucleotide variants and allow scoring of short insertions-deletions. C-scores correlate with allelic diversity, annotations of functionality, pathogenicity, disease severity, experimentally measured regulatory effects and complex trait associations, and they highly rank known pathogenic variants within individual genomes.
    Type: Application
    Filed: September 20, 2014
    Publication date: December 8, 2016
    Applicants: University of Washington through its Center for Commercialization, Hudsonsalpha Institute for Biotechnology
    Inventors: Jay Shendure, Gregory M Cooper, Martin Kircher, Daniela Witten