Abstract: Provided is an apparatus for manufacturing a semiconductor or metal oxide ingot by sequentially inducing a liquid-to-solid phase transition of a liquid raw material following a solidification direction, the apparatus including: a crucible containing a semiconductor or metal oxide raw material; a cooling unit spaced apart from the crucible at a predetermined distance in a vertical direction, when a height direction of the crucible is designated by the vertical direction and a direction perpendicular to the vertical direction is designated by a horizontal direction; a first heating unit spaced apart from the crucible at a predetermined distance in the horizontal direction and surrounding a circumferential surface of the crucible; and an insulating member provided between the crucible and the cooling unit in the horizontal direction, a position of the insulating member being shifted by a shifting unit.

Abstract: The present invention relates to a bidirectional voice transmission system and a method thereof, wherein the system timing of the system is divided into three time slots for carrying a control signal, a broadcast voice signal and a mobile device voice signal. The bidirectional voice transmission system is able to carry out the signal transmission by way of frequency frogging, so as to effectively avoid the signal interference from occurring between any two different signal transmitting and receiving devices. Besides, all of the mobile devices can be added into the bidirectional voice transmission system by way of dynamic building, without using any specific communication interface. The most important is that, the number of node routers can be expanded to about 65,000 in order to apply the bidirectional voice transmission system in a huge range network communication or a wild rescue field.

Abstract: The present disclosure provides an isolated, engineered or non-naturally occurring protein comprising an antibody light chain variable domain (VL) which may comprise at least one negatively charged amino acid positioned between residues 49 to 56 according to the numbering system of Kabat, the protein capable of binding specifically to an antigen.

Abstract: A humanized antibody, or a binding fragment thereof, wherein the humanized antibody binds human ENO1 (GenBank: AAH50642.1), wherein the antibody comprises a light chain variable region (VL) domain comprising a CDR1 having the amino acid sequence LCDR1 (RASENIYSYLT; SEQ ID NO: 6) and a CDR2 having the amino acid sequence LCDR2 (NAKTLPE; SEQ ID NO: 7) and a CDR3 having the amino acid sequence LCDR3 (QHHYGTPYT; SEQ ID NO: 8) and an antibody heavy chain variable region (VH) domain comprising a CDR1 having the amino acid sequence HCDR1 (GYTFTSCVMN; SEQ ID NO: 3), a CDR2 having the amino acid sequence HCDR2 (YINPYNDGTKYNEKFKG; SEQ ID NO: 4) and a CDR3 having the amino acid sequence HCDR3 (EGFYYGNFDN; SEQ ID NO: 5), wherein framework regions in the light chain variable region (VL) domain and the heavy chain variable region (VH) domain comprise amino acid sequences from a human immunoglobulin.

Abstract: Methods and devices for preparing microscale polymer relief structures from a thin polymer layer on an absorbing substrate are described. The described methods are ultrafast (about 8 nanoseconds) and allow formation of patterned microstructures having complex morphologies and narrow line widths that are an order of magnitude smaller than the masks used in the methods.

Abstract: The present invention relates to new salts of pyrazolopyrimidinone represented by formula (I), and pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystallization, anhydrous, or amorphous form thereof, the pharmaceutical compositions, and a pharmaceutical unit dosage form containing the same, wherein x represents organic or inorganic acids, preferable maleic acid, succinic acid, methanesulfonic acid, hydrochloric acid, etc. The invention further relates to co-crystals or complexes of compounds of pyrazolopyrimidinone and pharmaceutical compositions containing the same. The present invention also relates to a process for the preparation, use thereof and pharmaceutical preparation containing the salts or crystalline forms.

Abstract: Disclosed herein are compositions, systems and methods for delivery of proteins of interest using adeno-associated virus (AAV) vectors.

Abstract: The invention provides aromatherapy devices that may be used to break a capsule containing a desired aromatic liquid, and then control the release of the aroma as the volatile aromatic liquid evaporates. The devices may be used, for example, in aromatherapy, including to control nausea or to mask unpleasant scents.

Abstract: A node processor and method for performing matrix operations includes storing, in memory, non-zero matrix elements of a first sparse matrix, non-zero matrix elements of a second sparse matrix, and matrix elements of a sparse results matrix mapped to the node processor. A matrix communications module exchanges with other node processors, non-zero matrix elements of one or more of the first sparse matrix, second sparse matrix, and sparse results matrix. An arithmetic logic unit generates partial results based on the non-zero matrix elements of the first sparse matrix and on the non-zero matrix elements of the second sparse matrix stored in memory. The arithmetic logic unit further generates a final value for each matrix element of the sparse results matrix mapped to the node processor based on the partial results generated by the arithmetic logic unit and on partial results received from the other node processors.

Abstract: The present invention relates to compounds that are useful for modulating hepatic cholesterol metabolism in an animal. The invention includes methods of making and using the compounds of the invention. The invention further provides methods of treating, preventing and/or alleviating a cholesterol related disorder, a cardiovascular disease and/or liver disease in an animal, such as a human, comprising administering compounds of the invention, or pharmaceutically acceptable salts or solvates thereof, to the animal.

Abstract: The present invention relates to identification of Zinc-ZIP8-MTF1 axis that plays an important role to OA (osteoarthritis) pathogenesis process and a novel use thereof. According to the present invention, ZIP8 and MTF1 of the present invention increase in the expression in joint disease induced cells or cartilage tissue, and induce the expression of various matrix-degrading enzymes (e.g., MMP-3, MMP-9, MMP-12, MMP-13 and ADAMTS-5 etc.). In addition, when the expression of ZIP8 or MTF1 is inhibited in cells or tissues of animals (e.g., human, mouse), OA pathogenesis is inhibited. Therefore, the ZIP8 and MTF1 of the present invention may be applied to the diagnosis or prognosis of joint diseases, and may be used for the development of therapeutics for joint diseases using these.

Abstract: A thermionic power generator includes an emitter generating thermions and a collector collecting the thermions. The emitter includes an emitter substrate having an electric conductivity, a low resistance layer stacked to the emitter substrate and made of an n-type diamond semiconductor that includes phosphorus as a donor, and an electron emission layer stacked to the low resistance layer and made of an n-type diamond semiconductor that includes nitrogen as a donor. The collector includes a collector substrate having an electric conductivity and is disposed opposite to the emitter via a clearance. The electron emission layer has a thickness equal to or less than 40 nm.

Abstract: An inter-prediction method according to the present invention comprises the steps of: deriving motion information of a current block; and generating a prediction block for the current block on the basis of the derived motion information. According to the present invention, computational complexity can be reduced and encoding efficiency can be improved.

Abstract: The present invention relates to an Aster glehni extract, a fraction thereof and the active compounds isolated therefrom, which are effective for the treatment, prevention and improvement of hyperuricemia or gout. The Aster glehni extract, the fraction thereof and 6?-O-caffeoylampelopsisionoside, 6?-O-caffeoylroseoside, 6?-O-caffeoylsonchuinoside C, 6?-O-caffeoyldihydrosyringin and glehnoside as the active compounds isolated from the fraction according to the present invention have substantial effect of inhibiting production of uric acid and decreasing its concentration. Accordingly, the Aster glehni extract, the fraction thereof and the active compounds isolated therefrom the fraction according to the present invention can be effectively used as an active ingredient of a drug, health food, etc. for the treatment, prevention and improvement of such as hyperuricemia or gout, which are diseases induced by increased level of uric acid.

Abstract: This invention provides a novel method for producing a lactide-lactone copolymer. The method is characterized by copolymerizing a lactide and a lactone using a molybdenum compound as a catalyst.

Abstract: Disclosed are a method of device-to-device discovery and an apparatus for the same. A method of device-to-device discovery performed in a discovery terminal may include receiving a discovery identifier of the discovery terminal from a device-to-device server; performing an authorization procedure on performing the restricted discovery of an application located in the discovery terminal with the device-to-device server; and obtaining terminal information of a discoverable terminal as a counterpart terminal with which performs the restricted discovery from the device-to-device server, when the authorization is completed. Thus, the device-to-device discovery may be performed efficiently.

Abstract: A flow energy harvesting device having a harvester pipe includes a flow inlet that receives flow from a primary pipe, a flow outlet that returns the flow into the primary pipe, and a flow diverter within the harvester pipe having an inlet section coupled to the flow inlet, a flow constriction section coupled to the inlet section and positioned at a midpoint of the harvester pipe and having a spline shape with a substantially reduced flow opening size at a constriction point along the spline shape, and an outlet section coupled to the constriction section. The harvester pipe may further include a piezoelectric structure extending from the inlet section through the constriction section and point such that the fluid flow past the constriction point results in oscillatory pressure amplitude inducing vibrations in the piezoelectric structure sufficient to cause a direct piezoelectric effect and to generate electrical power for harvesting.

Abstract: Disclosed are a graphene-ceramic hybrid coating layer formed from a graphene-ceramic hybrid sol solution including graphene (RGO: reduced graphene oxide) and a ceramic sol, wherein the graphene content in the graphene-ceramic hybrid coating layer is about 0.001 wt % to about 1.8 wt % based on the total weight of the graphene-ceramic hybrid coating layer, and a method for preparing the same.

Abstract: A polyp detection apparatus and a method of operating the same are provided. The method of operating a polyp detection apparatus includes: generating an image of an object; detecting a polyp candidate region based on the generated image; detecting a reflected light region within the detected polyp candidate region; and displaying a final polyp region by excluding the detected reflected light region from the polyp candidate region.

Abstract: The present application discloses a control method of a fire fighting truck for high-rise and super high-rise building firefighting, including: a command control equipment (2), a launch control equipment (3), a turret control apparatus (8), a photoelectric detection equipment (9), wherein the photoelectric detection equipment (9) comprises: an installing shell, a power supply, a white light zoom camera, an infrared camera, a laser rangefinder, and an integrated processing unit, the white light zoom camera is connected to the installing shell by a screw, the infrared camera is connected to the installing shell by a screw, the laser rangefinder is connected to the installing shell by a screw, a power supply interface of the white light zoom camera is connected to the power supply by a wire, a power supply interface of the infrared camera is connected to the power supply by a wire, a power supply interface of the laser rangefinder is connected to the power supply by a wire, a data interface of the white light zo