Patents Assigned to INSTITUTE
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Publication number: 20160228352Abstract: Compositions comprising extracts from marine organisms show beneficial effects on skin ailments. Fine lines, wrinkles, and sagging in skin are improved with the application of compositions with marine extracts. Production of collagen, elastin and hyaluronic acid are increased after application of the compositions.Type: ApplicationFiled: April 14, 2016Publication date: August 11, 2016Applicant: I Commercial Marine Biology Institute, LLCInventor: Eric Lewis
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Publication number: 20160231314Abstract: In various aspects the invention provides methods of predicting sensitivity of a cancer cell to a therapeutic agent by contacting a test cell population BH3 domain peptide; measuring the amount of BH3 domain peptide induced mitochondrial outer membrane permeabilization in the test cell population; and comparing the amount of BH3 domain peptide induced mitochondrial outer membrane permeabilization in the test cell population to a control cell population that has not been contacted with the therapeutic agent. An increase in mitochondrial membrane permeabilization in the test cell population compared to the control cell population indicates the cell is sensitive to the therapeutic agent.Type: ApplicationFiled: September 18, 2014Publication date: August 11, 2016Applicant: Dana-Farber Cancer Institute, Inc.Inventors: Jeremy Ryan, Anthony Letai
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Patent number: 9409147Abstract: The present invention relates to a method for granulation of an absorbent and adsorbent granules prepared by the same. The method comprises the steps of blending sodium metasilicate, metakaoline and an inorganic ion exchange material in water to form a slurry; decanting the resulted slurry onto a nylon cloth of 300 to 400 meshes and natural drying at ambient temperature to solidification; then breaking the solidified final product and sieving it by a screen having a mesh size of from 0.2 to 2.5 mm to provide the absorbent granules having excellent absorbability.Type: GrantFiled: August 7, 2014Date of Patent: August 9, 2016Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUANInventors: Sheng-Wei Chiang, Kuang-Li Chien, Jen-Chieh Chung, Shih-Che Huang, Chi-Hung Liao, Kou-Min Lin
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Patent number: 9410959Abstract: A semiconductor nanocrystal heterostructure has a core of a first semiconductor material surrounded by an overcoating of a second semiconductor material. Upon excitation, one carrier can be substantially confined to the core and the other carrier can be substantially confined to the overcoating.Type: GrantFiled: August 24, 2012Date of Patent: August 9, 2016Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Sungjee Kim, Moungi G. Bawendi
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Patent number: 9412013Abstract: A hand motion recognizing apparatus obtains an image with first resolution including a hand and an image with second resolution higher than the first resolution including the hand, maps the image with the first resolution and the image with the second resolution, extracts a hand position from the image with the first resolution, obtains a hand region corresponding to the hand position from the image with the second resolution mapped to the image with the first resolution, and subsequently estimates a hand motion from the hand region.Type: GrantFiled: January 7, 2015Date of Patent: August 9, 2016Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Moon Wook Ryu, Soonchan Park, Ju Yong Chang, Ji Young Park, Kwang Hyun Shim, Hee Kwon Kim, Hyuk Jeong, Seung Woo Nam
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Patent number: 9410176Abstract: This invention relates to a method for producing a protein of interest, comprising introducing an expression vector which comprises a gene fragment comprising a DNA encoding the protein of interest and a selectable marker gene and also comprises a pair of transposon sequences at both terminals of the gene fragment, into a suspension mammalian cell; integrating the gene fragment inserted between the pair of transposon sequences into a chromosome of the mammalian cell; obtaining a suspension mammalian cell producing the protein of interest; and suspension-culturing the suspension mammalian cell, and a suspension mammalian cell which expresses the protein of interest by the method.Type: GrantFiled: December 14, 2011Date of Patent: August 9, 2016Assignees: Inter-University Research Institute Corporation Research Organization of Information and Systems, KYOWA HAKKO KIRIN CO., LTD.Inventors: Megumi Kurokawa, Yoko Hayashi, Masayoshi Tsukahara
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Patent number: 9408917Abstract: The disclosure provides a pharmaceutical composition. The pharmaceutical composition includes a chitosan with palmitoyl groups and an active agent. According to another embodiment, the pharmaceutical composition can further include a gelling accelerating agent. According to an embodiment of the disclosure, the active agent of the disclosure can be administered in the form of a nano-drug, liposome, micelle, or microparticle.Type: GrantFiled: June 25, 2013Date of Patent: August 9, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Maggie J. M. Lu, Yu-Wen Lo, Chih-Peng Liu, Chia-Wen Huang, Shuen-Hsiang Chou, Po-Hung Lai, Tsan-Lin Hu, Min-Ying Lin, Chia-Mu Tu
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Vacuum ultraviolet photoionization and chemical ionization combined ion source for mass spectrometry
Patent number: 9412577Abstract: This invention relates to the field of mass spectrometry, and more specifically to a vacuum ultraviolet photoionization and chemical ionization combined ion source, which consists of a vacuum ultraviolet light source and an ion source chamber. An ion acceleration electrode, an ion repulsion electrode, an ion extraction electrode, and a differential interface electrode positioned inside the ion source chamber are arranged along the exit direction of the vacuum ultraviolet light beam in sequence and spaced, coaxial, and parallel from each other. The ion acceleration electrode, the ion repulsion electrode, the ion extraction electrode, and the differential interface electrode are all plate structures with central through holes. The vacuum ultraviolet light beam passes through the central through holes of the electrodes along the axial direction.Type: GrantFiled: February 17, 2011Date of Patent: August 9, 2016Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Haiyang Li, Lei Hua, Qinghao Wu, Huapeng Cui, Keyong Hou -
Patent number: 9412173Abstract: A method for mapping an environment comprises moving a sensor along a path from a start location (P0) through the environment, the sensor generating a sequence of images, each image associated with a respective estimated sensor location and comprising a point cloud having a plurality of vertices, each vertex comprising an (x,y,z)-tuple and image information for the tuple. The sequence of estimated sensor locations is sampled to provide a pose graph (P) comprising a linked sequence of nodes, each corresponding to a respective estimated sensor location. For each node of the pose graph (P), a respective cloud slice (C) comprising at least of portion of the point cloud for the sampled sensor location is acquired. A drift between an actual sensor location (Pi+1) and an estimated sensor location (Pi) on the path is determined.Type: GrantFiled: April 22, 2014Date of Patent: August 9, 2016Assignees: National University of Ireland, Maynooth, Massachusetts Institute of TechnologyInventors: John Joseph Leonard, Michael Kaess, John McDonald, Thomas John Whelan
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Patent number: 9414235Abstract: The invention includes a method and apparatus for dynamically allocating spectrum available within a region including a plurality of base stations. The method includes obtaining a plurality of spectrum demands associated with at least a portion of the base stations, each spectrum demand requesting a portion of the available spectrum, and determining a plurality of spectrum allocations satisfying at least a portion of the spectrum demands. The spectrum allocations are determined by processing the spectrum demands using network information such as base station information associated with the base stations and region information such as terrain information associated with the region. The region information may include signal propagation information.Type: GrantFiled: February 13, 2015Date of Patent: August 9, 2016Assignees: Alcatel Lucent, Stevens Institute of TechnologyInventors: Milind M. Buddhikot, Scott C. Miller, Kevin Ryan
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Patent number: 9409157Abstract: Provided is a catalyst for preparing a syngas by reforming methane wherein a nickel-based catalyst is mixed with a metal oxide catalyst. More particularly, alumina is used as a support and a metal oxide catalyst including magnesia, nickel, vanadium, tungsten, iron, molybdenum or chromium is used to inhibit carbon deposition and maintain or improve catalytic activity.Type: GrantFiled: June 4, 2013Date of Patent: August 9, 2016Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Dong Ju Moon, Young Chul Kim, Hye Jeong Ok
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Patent number: 9410095Abstract: A method of gasification of biomass using a gasification island. The gasification island includes: a biomass pre-treatment and storage unit, a biomass feeder, an external heat source, a gasifier, a crude syngas cooling unit, a crude syngas washing unit, a fresh syngas storage unit, and an ash and wastewater treatment unit. The method includes: pre-treating and storing biomass, gasifying the biomass in the gasifier, cooling a crude syngas, washing and removing dust from the crude syngas, and storing fresh syngas.Type: GrantFiled: June 26, 2014Date of Patent: August 9, 2016Assignee: WUHAN KAIDI ENGINEERING TECHNOLOGY RESEARCH INSTITUTE CO., LTD.Inventors: Yanfeng Zhang, Minggui Xia, Hongtao Nie, Wenyan Liu, Liang Zhang
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Patent number: 9412967Abstract: A foldable package structure including a first substrate, a second substrate, a plurality of adhesive layers and at least one environmental-sensitive electronic component is provided. At least one of the first and second laminated substrates comprises an ultra-thin glass plate. The foldable package structure comprises a predetermined folded region and the ultra-thin glass plate is disposed at one side of the predetermined folded region and stays away from the predetermined folded region.Type: GrantFiled: October 30, 2014Date of Patent: August 9, 2016Assignee: Industrial Technology Research InstituteInventors: Kuang-Jung Chen, Cheng-Chung Lee
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Patent number: 9410206Abstract: Long noncoding RNAs (lncRNAs) that may be used as cancer biomarkers and methods of diagnosing, prognosing and monitoring cancer including, but not limited to, cutaneous melanoma using said lncRNAs are provided herein. In some embodiments, the methods include steps of isolating one or more lncRNA transcripts in a biological sample from the subject; measuring a test level of the one or more isolated lncRNA transcripts; comparing the test level to a control level of the one or more lncRNA transcripts; and diagnosing or making a prognosis based on the lncRNA level. In some embodiments, the lncRNA transcript is an linc00340 transcript or variant thereof. These lncRNA transcripts may also be used as a therapeutic target in the treatment of cancer.Type: GrantFiled: November 30, 2012Date of Patent: August 9, 2016Assignee: JOHN WAYNE CANCER INSTITUTEInventors: Dave S. B. Hoon, Laurent Lessard
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Patent number: 9412657Abstract: In a method for manufacturing a semiconductor, a Through Silicon Via (TSV) template wafer and production wafers form a sandwich structure, in which the TSV template wafer has TSV structures uniformly distributed therein, for providing electrical connection between the production wafers to form 3D interconnection. The TSV template wafer is obtained by thinning a semiconductor wafer, which facilitates reducing the difficulty in etching and filling. Connection parts are provided on the TSV template wafer, for convenience of interconnection between the overlying and underlying production wafers, which facilitates reducing the difficulty in alignment and improving the convenience of design of electrical connection for 3D devices.Type: GrantFiled: November 17, 2015Date of Patent: August 9, 2016Assignee: Institute of Microelectronics, Chinese Academy of SciencesInventors: Huicai Zhong, Chao Zhao, Huilong Zhu
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Patent number: 9408910Abstract: The present invention relates to an anticancer prodrug consisting of peptide of acetyl-SEQ ID NO: 1-linker-anticancer drug. The anticancer prodrug effectively provides an anticancer drug unstable in acid or base, such as doxorubicin, in a form of prodrug. Thus, the anticancer prodrug exists as a non-toxic inactive form when administered into the body, but effectively releases the anticancer drug as an active ingredient in the target area in the presence of caspase activated by radiation or UV treatment after administered into the body. Accordingly, the anticancer drug exhibits selective anticancer effects on cancer cells, thereby maximizing the therapeutic effect and minimizing the side-effects of chemotherapy.Type: GrantFiled: March 2, 2011Date of Patent: August 9, 2016Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Ju-Hee Ryu, Kwang-Meyung Kim, Ick-Chan Kwon, Kui-Won Choi, Sang-Yoon Kim, Beom-Suk Lee, Dae-Yoon Chi, Hee-Seup Kil, Hyun-Ju Sung
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Patent number: 9414236Abstract: Provided is a resource management system in a communication system including a plurality of systems having no right to use a first frequency band. The resource management system includes: a coexistence manager (CM) configured to manage the plurality of systems for the purpose of coexistence and frequency sharing of the plurality of systems in a frequency band available for the plurality of systems, when the available frequency band is detected in the first frequency band; a coexistence enabler (CE) configured to transmit and receive information of the plurality of systems and information of the CM; and a coexistence discovery and information server (CDIS) configured to support the CM to control the plurality of systems. The CM performs channel classification for the first frequency band based on channel information of the available frequency band, and allocates operating channels to the plurality of systems.Type: GrantFiled: November 10, 2011Date of Patent: August 9, 2016Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Hyunduk Kang, Dong-Hun Lee
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Patent number: 9410128Abstract: The present invention is based on the seminal concept of combining genomics and chemical biology to identify new agents useful for induced pluripotent stem cell (iPSC) generation. The invention provides a method of generating an iPSC utilizing agents that antagonize a cell specific gene or upregulate expression or activity of a nuclear reprogramming gene, as well as a method of screening for such agents.Type: GrantFiled: February 22, 2012Date of Patent: August 9, 2016Assignee: Sanford-Burnham Medical Research InstituteInventor: Tariq M. Rana
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Patent number: 9411097Abstract: Provided herein is an optical module including an optical bench having a first step with a first depth and a second step with a second depth that is smaller than the first depth; a silicon carrier disposed above the first step, and where at least one semiconductor chip is installed; an AWG chip (Arrayed Waveguide Grating chip) secured to the second step, extends up to the first step, and is chip-to-chip bonded with the silicon carrier above the first step; a lens disposed on an upper surface of the optical bench where the first step and the second step are not formed; and a metal package surrounding the optical bench, silicon carrier, AWG chip and lens, wherein at one side of the metal package, a double slit that includes an upper slit and a lower slit are formed, a DC FPCB (Direct Current FPCB) extends from outside towards inside the metal package through the upper slit and is secured to a support formed on an inner surface of the upper slit, and an RF FPCB (Radio Frequency FPCB) extends from outside towardsType: GrantFiled: June 1, 2015Date of Patent: August 9, 2016Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Young Tak Han, Sang Ho Park, Yong Soon Baek, Jang Uk Shin
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Patent number: 9411026Abstract: This computation device and method exponentially shortens a computation time of an NP-complete problem or the like mapped into an Ising model by exponentially shortening a computation time of the Ising mode. For each pair of a plurality of slave lasers, by controlling the intensity, the polarization, and the phase of light exchanged between two slave lasers using an attenuator and a wave plate, the magnitude and the sign of pseudo Ising interaction between two slave lasers are implemented. Then, after the plurality of slave lasers arrive at a steady state, by measuring the polarization of light generated by each slave laser with left-handed circular polarization and right-handed circular polarization used as bases, a pseudo spin of each slave laser is measured.Type: GrantFiled: February 28, 2012Date of Patent: August 9, 2016Assignee: INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, RESEARCH ORGANIZATION OF INFORMATION AND SYSTEMSInventors: Yoshihisa Yamamoto, Shoko Utsunomiya, Kenta Takata, Kai Yan