Abstract: Disclosed herein are compounds, compositions and methods for preventing and treating diseases such as intracerebral hemorrhage, cancer, or conditions associated with damaged cells, activated lymphocytes, or microbial products. The disclosed compounds are curcumin analogs. The curcumin analogs possess anti-inflammatory and antioxidant properties, which in part, reduce AP-1 and NF-?B activity.
Type:
Grant
Filed:
September 22, 2014
Date of Patent:
June 21, 2016
Assignees:
Augusta University Research Institute, Inc., East China Normal University
Inventors:
Cargill H. Alleyne, Jr., Krishnan M. Dhandapani, Ken Wen, MingLiang Ma, WenJing Hu
Abstract: [Structure] An olfactory display 10 includes a housing 12 having an emitting port 22, and presents a fragrance within a range bounded in terms of time and space. Within the housing 12, a fragrance chamber 14 having an air inlet 26 and a fragrance outlet 24 which is communicated with the emitting port 22 is formed, and in the fragrance chamber 14, a solid-like fragrance source 20 is accommodated. Furthermore, in the fragrance chamber 14, there is provided with a airflow source 16 comprising a diaphragm 34 having a piezoelectric device 32. In presenting a fragrance, an air is sent into the fragrance chamber 14 from the air inlet 26 by the airflow source 16, and accordingly, the air within the fragrance chamber 14, which including a gas-like fragrance component volatilized from the fragrance source 20 is emitted from the emitting port 22 passing through the fragrance outlet 24.
Type:
Grant
Filed:
July 27, 2012
Date of Patent:
June 21, 2016
Assignee:
National Institute of Information and Communications Technology
Abstract: A polyamide-imide represented by the following formula is provided. A graphite film prepared by performing a thermal treatment process on the polyamide-imide represented by the above-mentioned formula is also provided. In the thermal treatment process, the temperature range of the thermal treatment process ranges from 25° C. to 2,900° C.
Type:
Grant
Filed:
September 12, 2014
Date of Patent:
June 21, 2016
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, prevention, and therapy of disease.
Abstract: Disclosed are a gas sensor, and a method of manufacturing and using the same. The method includes: forming a detection material on a heater; coating an encapsulant on the detection material; and heating the heater to remove the encapsulant from the detection material when the gas sensor is operated.
Type:
Grant
Filed:
August 24, 2012
Date of Patent:
June 21, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Hyung Kun Lee, Woo Seok Yang, Nak Jin Choi, Seung Eon Moon, Jong Dae Kim
Abstract: An optical access system is provided that enables subscriber terminals or termination devices to be interconnected via dedicated lines as needed, with respect to subscriber terminals or termination devices participating in an optical network. The optical network is a network connecting a plurality of accommodating stations, and in this network, the accommodating stations have a plurality of optical line termination devices and optical path selection means, the subscriber side optical terminals or optical line termination devices are connected in single star optical paths, and the optical line termination devices in the accommodating stations are connected with the above mentioned optical terminals or optical line termination devices via the optical path selection means.
Type:
Grant
Filed:
December 12, 2011
Date of Patent:
June 21, 2016
Assignee:
NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
Abstract: The present invention provides a method for producing a plant with a stress tolerance, comprising the step of inhibiting, in a plant, a function of a first polypeptide including an amino acid sequence represented by any one of SEQ ID NOS: 2, 4, 6, 8, and 10. This enables developing a new technique capable of producing a plant with a stress tolerance such as a salt tolerance and a high osmotic pressure tolerance.
Type:
Grant
Filed:
July 8, 2013
Date of Patent:
June 21, 2016
Assignees:
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, GREENSOGNA, INC.
Abstract: The phase rotation relates to an apparatus and method of indicating a bandwidth in a wireless communication system. This disclosure discloses a wireless device comprising a transmission transmitting and receiving a wireless signal and a processor operating in operative connection with the transmission, wherein the processor generates a PPDU (physical protocol data unit) to which a phase rotation application is selectively applied depending on a case of bandwidth indication or a case of no bandwidth indication.
Type:
Grant
Filed:
May 8, 2013
Date of Patent:
June 21, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Min Ho Cheong, Jae Seung Lee, Sok Kyu Lee
Abstract: The present invention is directed to isolated populations of human natural immunoglobulin-producing B1 lymphocytes, wherein the B1 lymphocytes display surface biomarkers CD20, CD43 and CD27 and are either CD11b+ or GD11b?. The present invention is also directed to a method of isolating human natural immunoglobulin-producing B1 lymphocytes from a blood sample comprising isolating B lymphocytes from the sample that express surface biomarkers CD20, CD43 and CD27, and, optionally, CD11b. In addition, the present invention is directed to a methods for diagnosing a B1 cell disorder in a patient, determining the prognosis of a patient having a B1 cell disorder, and treating a patient having a B1 cell disorder.
Type:
Grant
Filed:
September 22, 2011
Date of Patent:
June 21, 2016
Assignee:
The Feinstein Institute for Medical Research
Inventors:
Thomas L. Rothstein, Daniel O. Griffin, Nichol E. Holodick
Abstract: Compositions and methods for preparing nucleic acid nanotubes using DNA origami techniques are described, which provide for nanotubes of predictable and uniform length. The nucleic acid nanotubes thus formed are suitable as liquid crystal preparations enabling liquid-crystal NMR spectroscopy of proteins solubilized in detergent.
Type:
Grant
Filed:
April 20, 2011
Date of Patent:
June 21, 2016
Assignees:
Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
Inventors:
William M. Shih, Shawn M. Douglas, James J. Chou
Abstract: A rotary positioning apparatus includes a fixing base, a rotation mechanism, two driving modules and a carrier. The rotation mechanism is disposed on the fixing base, the first driving module is disposed on the fixing base and coupled to the rotation mechanism to drive the rotation mechanism rotating around a first rotation axis relatively to the fixing base. The carrier has plural accommodating slots on a circular-arc surface thereof and is pivoted to the rotation mechanism through a second rotation axis passing through the curvature center of the circular-arc surface and perpendicular to the first rotation axis, on which the curvature center is located. The second driving module is disposed on the rotation mechanism and coupled to the carrier to drive the carrier rotating around the second rotation axis relatively to the rotation mechanism. An automatic pick-and-place system and an operation method using the rotary positioning apparatus are also provided.
Type:
Grant
Filed:
November 19, 2013
Date of Patent:
June 21, 2016
Assignee:
Industrial Technology Research Institute
Abstract: An apparatus and method for 3D seismic exploration for use in a small ship. The apparatus includes a seismic source towed by the small ship from a rear side thereof, a pair of support rods connected to the rear side and horizontally arranged in two rows behind the seismic source in the direction extending from a sailing direction of the ship, and a plurality of streamers arranged between the support rods in the sailing direction of the ship.
Type:
Grant
Filed:
April 21, 2015
Date of Patent:
June 21, 2016
Assignees:
KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES, GEOVIEW CO. LTD.
Inventors:
Won Sik Kim, Jong Myung Park, Ho Young Lee, Young Jun Kim, Hyun Do Kim
Abstract: A resistive random access memory and a method for fabricating the same are provided. The method includes forming a bottom electrode on a substrate; forming a metal oxide layer on the bottom electrode; forming an oxygen atom gettering layer on the metal oxide layer; forming a first top electrode sub-layer on the oxygen atom gettering layer; forming a second top electrode sub-layer on the first top electrode sub-layer, wherein the first top electrode sub-layer and the second top electrode sub-layer comprise a top electrode; and subjecting the metal oxide layer and the oxygen atom gettering layer to a thermal treatment, driving the oxygen atoms of the metal oxide layer to migrate into and react with the oxygen atom gettering layer, resulting in a plurality of oxygen vacancies within the metal oxide layer.
Type:
Grant
Filed:
October 22, 2014
Date of Patent:
June 21, 2016
Assignee:
Industrial Technology Research Institute
Inventors:
Heng-Yuan Lee, Pang-Shiu Chen, Tai-Yuan Wu, Ching-Chiun Wang
Abstract: Provided is a wavelength converting structure for near-infrared rays and a solar cell using the same. More particularly, provided is a novel wavelength converting structure for near-infrared rays using gap plasmon characteristics and up-conversion nanoparticles. When applying the wavelength converting structure for near-infrared rays to a solar cell, it is possible to convert the light within a wavelength range of near-infrared rays into electric energy so that the photoconversion efficiency may be improved.
Type:
Grant
Filed:
January 27, 2015
Date of Patent:
June 21, 2016
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Hyungduk Ko, Ho Seong Jang, Doo-Hyun Ko, Il Ki Han, Gi Yong Lee
Abstract: A plasma generator according to an embodiment of the present invention is provided to generate a high density and stable plasma at near atmospheric pressure by preventing a transition of plasma to arc. The plasma generator includes a plate-shaped lower electrode for seating a substrate; and a cylindrical rotating electrode on the plate-shaped lower electrode, wherein the cylindrical rotating electrode includes an electrically conductive body that is connected to a power supply and includes a plurality of capillary units on an outer circumferential surface of the electrically conductive body; and an insulation shield layer that is made of an insulation material or a dielectric material, exposes a lower surface of the plurality of capillary units, and shields other parts.
Type:
Grant
Filed:
August 10, 2012
Date of Patent:
June 21, 2016
Assignee:
KOREA INSTITUTE OF MACHINERY & MATERIALS
Inventors:
Kee-Seok Nam, Jung-Dae Kwon, Yong Soo Jeong, Gun Hwan Lee, Jung Heum Yoon, Sung Hun Lee, Dong Ho Kim, Jae Wook Kang, Sung Gyu Park, Chang Su Kim
Abstract: A hole transport polymeric compound and a polymer light emitting diode using the same. The hole transport polymeric compound includes a hole transport material, a thermal cross-linking agent containing an ethynyl group, and a compound represented by [Formula 1], and can be applied to a polymer light emitting diode. In addition, the hole transport polymeric compound has excellent hole transport capabilities and has stability in solvents so as to be insoluble in a solvent used upon stacking other organic layers and blocking electrons well.
Type:
Grant
Filed:
July 2, 2013
Date of Patent:
June 21, 2016
Assignee:
GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: An apparatus and a method for an attack source traceback capable of tracing back an attacker, that is, an attack source present behind a command and control (C&C) server in a cyber target attack having non-connectivity over a transmission control protocol (TCP) connection are disclosed. The apparatus for the attack source traceback includes: a server information extracting unit detecting an attack for a system, which is generated via a server to thereby extract information on the server; a traceback agent installing unit installing a traceback agent in the server based on the information on the server; and a traceback unit finding an attack source for the system by analyzing network information of the server obtained by the traceback agent.
Type:
Grant
Filed:
October 20, 2014
Date of Patent:
June 21, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Min-Ho Han, Jung-Tae Kim, Ik-Kyun Kim, Hyun-Sook Cho
Abstract: Provided are an apparatus and method for maintaining cache coherency, and a multiprocessor apparatus using the method. The multiprocessor apparatus includes a main memory, a plurality of processors, a plurality of cache memories that are connected to each of the plurality of processors, a memory bus that is connected to the plurality of cache memories and the main memory, and a coherency bus that is connected to the plurality of cache memories to transmit coherency related information between caches. Accordingly, a bandwidth shortage phenomenon may be reduced in an on-chip communication structure, which occurs when using a communication structure between a memory and a cache, and communication for coherency between caches may be simplified.
Type:
Grant
Filed:
September 18, 2013
Date of Patent:
June 21, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: The present invention provides a novel endo-?-N-acetylglucosaminidase (Endo-Om) using a transformant produced by cloning an endo-?-N-acetylglucosaminidase (Endo-Om) gene originated from a methylotrophic yeast Ogataea minuta IFO10746 strain. The Endo-Om according to the present invention has a specific activity 13-fold higher than that of known Endo-M and a Vmax value 55-fold higher than that of the known Endo-M, and is useful for the analysis of the structures of sugar chains, including complex type sugar chains, in glycoproteins and the modification of the sugar chains.
Type:
Grant
Filed:
October 3, 2012
Date of Patent:
June 21, 2016
Assignee:
National Institute of Advanced Industrial Science and Technology