Abstract: The invention provides methods of monitoring differential gene expression of biomarkers to determine patient sensitivity to Cyclin Dependent kinase inhibitors (CDKi), methods of determining the sensitivity of a cell to a CDKi, methods of treating a patient with a CDKi and methods of screening for candidate CDKi.

Abstract: Embodiments of the invention provide a method detecting and treating cancer, such as lung cancer. In some aspects, the method may include detecting cancer in a subject, which may comprise assessing the expression of a marker in a sample from the subject. For example, the marker may comprise c-Met and/or Fn14. In some embodiments, if the subject is diagnosed as having cancer, the method may further provide administering a therapeutically effective amount of a substance that reduces the expression level of Fn14 to the subject to reduce the invasive and migratory capabilities of the cancer.

Abstract: A precursor for labeling therapeutic agents for liver cancer and a method for manufacturing the same are revealed. The chemical structure of the precursor has a ligand linked to complex compounds of radioisotopes. Moreover, the chemical structure of the precursor further includes a specific functional group soluble in Lipiodol or having properties of Lipiodol. Thus the radioisotopes attached to the precursor are allowed to retain in hepatic tissues of patients with liver cancer for internal radiation therapy of liver cancer.

Abstract: A one-pot synthesis of Nb5+-doped TiO2 nanoparticles (NPs) with low cost and high efficiency for dye sensitized solar cells (DSSCs) is disclosed in the present invention. The Nb5+-doped TiO2 NPs with Nb dopants of 0˜5 mol % are prepared by directly mixing TiO2 slurry with Nb2O5 gel obtained by UV treatment of a mixture of NbCl5 powder, ethanol and water in a certain ratio, following by heat treatment without using hydrothermal method. The as-prepared NPs exhibit well-crystallized pure anatase TiO2 phase with uniform particle distribution. The incorporation of Nb5+ leads to a stronger and broader light absorption in visible light range and a decrease of band gap with increasing Nb dopant content, which enhances the efficiencies of light-harvesting and electron injection and suppresses the charge recombination. The present method provides a simple and cost-effective mass-production route to synthesize n-type metallic ion doped TiO2 nanoparticles as excellent photoanode materials.

Abstract: Provided are a mineralizing removal method and apparatus for highly concentrated iodine in radioactive wastewater. According to the present invention, since only a small amount of sludge is discharged as compared to the previous treatment methods, a generation amount of the radioactive waste may be significantly decreased, such that wastewater containing highly or ultra-highly concentrated iodine may also be effectively treated. Further, only iodine may be selectively removed regardless of the presence of competitive anions in the wastewater. Treatment may be performed under a neutral or weak alkaline condition rather than an acidic condition, such that a volatilization of radioactive iodine was fundamentally blocked, and at the time of discharging the wastewater, a neutralization treatment process is not required.

Abstract: An air data sensor device using a flow around a cylinder is provided. The air data sensor device may include a sensor measurement unit which includes a sensor body provided in a cylindrical form including a hollow inside, a plurality of pressure measurement holes disposed on an outside of the sensor body, and a thermostat attached to one side of the sensor body, and a signal processing unit which includes a pressure sensor connected to the plurality of pressure measurement holes, and a microprocessor connected to the pressure sensor to perform calculation. A main pressure measurement hole having a high pressure value may be selected from the plurality of pressure measurement holes, pressure distribution may be calculated, and at least one of an angle of attack, a static pressure, and a total pressure may be calculated using the pressure distribution.

Abstract: Disclosed is a method for treating a surface of a PVC product. A PVC product including PVC and plasticizer is provided. A surface of the PVC product is treated by an aqueous solution of a crosslinking agent and a first phase transfer catalyst to form a first surface treated PVC product. The surface of the first surface treated PVC product is treated by an aqueous solution of an aqueous free radical initiator and a second phase transfer catalyst to form a second surface treated PVC product. As such, the release of the plasticizer from the PVC product to an environment is inhibited.

Abstract: An implanted parylene tube shunt relieves intra-ocular pressure. The device is implanted with an open end in the anterior chamber of the eye, allowing excess fluid to be drained through the tube out of the eye. In one embodiment, only a first end of the tube implanted into the anterior chamber of the eye is open. Intra-ocular pressure (IOP) is then monitored, for example utilizing an implanted sensor. When IOP exceeds a critical valve, a practitioner intervenes, puncturing with a laser a thinned region of the tube lying outside the eye, thereby initiating drainage of fluid and relieving pressure. In accordance with alternative embodiments, the both ends of the tube are open, and the tube includes a one-way valve configured to permit drainage where IOP exceeds the critical value. The tube may include projecting barbs to anchor the tube in the eye without the need for sutures.

Abstract: A method of setting a cycle of a low-duty mode in a femto base station is provided. The cycle of the low-duty mode has a pattern in which an available interval and an unavailable interval repeatedly appear, and the available interval is set to include a paging listening interval of a paging cycle. A method of setting a cycle of a low-duty mode in a femto base station having a service area overlapping with that of a macrocell is provided. An unavailable interval is set by taking the overlapping degree of the service area of the femto base station with the macrocell into consideration. A method of setting a cycle of a low-duty mode in a plurality of femto base stations operated in the low-duty mode is provided. The same cycle can be set for a plurality of base stations.

Abstract: An apparatus and method for controlling a sensor node are provided that may calculate an azimuth angle and a slope of the sensor node using a 2-axis magnetic sensor and a 3-axis acceleration sensor, and may detect a target approaching the sensor node. The apparatus may include a calculation unit to calculate an azimuth angle and a slope of a sensor node, based on a magnetic values measured by a 2-axis magnetic sensor and a acceleration values measured by a 3-axis acceleration sensor; a sensor control unit to filter the magnetic values and the vibration values and to amplify the filtered magnetic values and the filtered vibration values, when the azimuth angle and the slope are calculated; and a detection unit to detect a target based on the amplified magnetic values and the amplified vibration values.

Abstract: A silicon carbide vertical field effect transistor includes a first-conductive-type silicon carbide substrate; a low-concentration first-conductive-type silicon carbide layer formed on a surface of the first-conductive-type silicon carbide substrate; second-conductive-type regions selectively formed on a surface of the first-conductive-type silicon carbide layer; first-conductive-type source regions formed in the second-conductive-type regions; a high-concentration second-conductive-type region formed between the first-conductive-type source regions in the second-conductive-type region; a source electrode electrically connected to the high-concentration second-conductive-type region and a first-conductive-type source region; a gate insulating film formed from the first-conductive-type source regions formed in adjacent second-conductive-type regions, onto the second-conductive-type regions and the first-conductive-type silicon carbide layer; a gate electrode formed on the gate insulating film; and a drain elec

Abstract: A method in a data processing system and apparatus for organizing files or web pages, structured or unstructured, of multiple users stored across one or more server computers into hierarchical file structures on a recordable medium of a data processing system. A user-defined metalabel is assigned to each of the electronic files or web pages. The electronic files or web pages are organized as a function of the metalabels into the hierarchical file structures.

Abstract: A compound represented by the formula (1): wherein Xa and Ya are each a single bond and the like, cancer antigen peptide A is an MHC class I-restricted WT1 peptide consisting of 7-30 amino acid residues, R1 is a hydrogen atom, a group represented by the formula (2): wherein Xb and Yb are each a single bond and the like, cancer antigen peptide B has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide consisting of 7-30 amino acid residues, or cancer antigen peptide C, and cancer antigen peptide C has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide or an MHC class II-restricted WT1 peptide, consisting of 7-30 amino acid residues containing one cysteine residue, or a salt thereof, and the like.

Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).

Abstract: Disclosed are a climbing shoes outsole with good adhesive and non-slip properties and a method for manufacturing the same. More specifically, the climbing shoes outsole comprises a butyl rubber layer formed at a side of the outsole in contact with the ground, and a general-purpose rubber layer laminated on the butyl rubber layer.

Abstract: The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.

Abstract: A resonator structure for a wireless power transfer system Includes resonators, which are to transfer wireless power, and a dielectric substance, which includes at least one exposure region formed on the dielectric substance to fix the resonators in a covered shape and to selectively expose parts of the resonators.

Abstract: Provided is an analysis apparatus for a high energy particle and an analysis method for a high energy particle. The analysis apparatus for the high energy particle includes a scintillator generating photons with each unique wavelength by the impinging with a plurality of kinds of accelerated high energy particles, a parallel beam converting unit making the photons proceed in parallel to one another, a diffraction grating panel making the photons proceeding in parallel to one another enter at a certain angle, and refracting the photons at different angles depending on each unique wavelength, and a plurality of sensing units arranged on positions where the photons refracted at different angles from the diffraction grating panel reach in a state of being spatially separated, and detecting each of the photons.

Abstract: An apparatus and method for generating a power delivery network (PDN) of a circuit system is provided. The apparatus performs a power diagnostics on the PDN of a circuit system. According to result of the power diagnostics, a number of areas are generated and divided into at least three subsets. At least one area is selected from each of the at least three subsets, and one node is selected from each of the selected areas, and the nodes are connected sequentially to form an interconnection with at least three nodes in the PDN.

Abstract: Provided is a device and a method for smart device and sensor node integrated application update, including an application program updating device including a generator to generate a package in a storage space by installing a sensing application, an extractor to extract an installation file and a profile of an application program interworking with the sensing application from the package, a recognizer to recognize a sensor node by referring to the profile, an installer to install the application program by transmitting the installation file to the sensor node, and an executor to execute the application program and the sensing application when the application program is installed in the sensor node.