Abstract: The present invention relates a prophylactic or therapeutic composition for cancer, and more particularly, to a prophylactic or therapeutic composition for cancer comprising a peptide which is represented by an amino acid sequence of the following Formula (I), a method for preventing or treating cancer comprising the step of administering the peptide to a subject, and use of the peptide in the preparation of the prophylactic or therapeutic composition for cancer. (I) APKAMX1LLX2X3L-LX4LQKKGI wherein X1, X2, X3 and X4 are each independently R or K.

Abstract: The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods, such as the reaction of Z-X with C(L)(R)(R?)2 in the present of a catalyst and a base, thereby forming C(Z)(R)(R?)2; wherein X represents I, Cl, alkylsulfonate, or arylsulfonate; Z represents optionally substituted aryl, heteroaryl or alkenyl; L represents H or a negative charge; catalyst comprises a copper atom or ion, and a ligand, wherein the ligand is an optionally substituted aryl alcohol, alkyl amine, 1,2-diamine, 1,2-aminoalcohol, 1,2-diol, imidazolium carbene, pyridine, or 1,10-phenanthroline; the ligand is a chelating ligand; and the base represents a Bronsted base; R represents H, optionally substituted alkyl, cycloalkyl, aralkyl, aryl, or heteroaryl; R? represents independently for each occurrence H, alkyl, cycloalkyl, aralkyl, aryl, or heteroaryl, formyl, acyl, —CO2R?, —C(O)N(R)2, sulfonyl, —P(O)(OR?)2, —CN, or —NO2; R? represents independently for each occurrence optionally substituted alky

Abstract: There are provided a method of generating a ranging signal of a wireless terminal and a device for generating a ranging signal of a wireless communication system that can generate the ranging signal using one IFFT engine independently from a mode of the ranging signal transmitted in uplink in a wireless communication system in which a frequency interval of subcarriers used to generate an initial ranging signal and a frequency interval of subcarriers using periodic ranging are different. In this way, it is possible to decrease complexity of hardware and design of the wireless terminal, and decrease power consumption of the wireless terminal through hardware simplification.

Abstract: In one aspect, the present invention provides for a compound of Formula I in which in Formula I, the variables X1, X2a, X2b, X2c, R1, B, L, E, A and the subscript n are as defined herein. In another aspect, the present invention provides for pharmaceutical compositions comprising compounds of Formula I as well as methods for using compounds of Formula I for the treatment of diseases and conditions (e.g., cancer, thrombocythemia, etc) characterized by the expression or over-expression of Bcl-2 anti-apoptotic proteins, e.g., of anti-apoptotic Bcl-xL proteins.

Abstract: An apparatus for determining a speed of cyclic motion of a device or user and one or more poses of a device may include a processor and memory storing executable computer code causing the apparatus to at least perform operations including receiving one or more determined acceleration values during one or more time periods in response to detected cyclic motion of a user moving with an apparatus. The computer program code may further cause the apparatus to transform the acceleration values to one or more corresponding frequency components associated with the acceleration values. The computer program code may further cause the apparatus to determine a speed of the cyclic motion of the user based in part on comparing a spectrum of the frequency components to one or more spectrums of distribution associated with respective one or more speeds of training data. Corresponding methods and computer program products are also provided.

Abstract: The present disclosure relates to an apparatus and method for anaerobic wastewater treatment with a membrane, which effectively generates biogas and suppresses fouling on a membrane surface by performing anaerobic treatment to wastewater. The apparatus for anaerobic wastewater treatment with a membrane includes: an anaerobic reactor for performing anaerobic treatment to wastewater and generating biogas; an anaerobic membrane bio-reactor for filtering wastewater discharged from the anaerobic reactor by means of a membrane module and providing an additional anaerobic treatment space for the wastewater; submerged membrane modules provided in the anaerobic membrane bio-reactor to filter wastewater; rotating disks provided at both sides of the submerged membrane module to induce turbulence to the wastewater by means of rotation; and a second media provided in the anaerobic membrane bio-reactor to circulate according to the flow of the wastewater so that foulants on a surface of the membrane module are detached.

Abstract: The inventive concept discloses a new temperature sensor structure based on oscillator which is insensitive to a process change and improves an error rate of temperature output. The temperature sensor based on oscillator compares an oscillator circuit structure insensitive to a temperature change with an oscillator circuit structure having a frequency change in proportion to a temperature change to output a relative difference between the two oscillator circuit structures and thereby it is compensated itself. In the temperature sensor based on oscillator, a problem of performance reduction due to an external environment and a process deviation of temperature sensor is improved and an output distortion and temperature nonlinearity are effectively improved. Thus, since the temperature sensor based on oscillator has a structure of high performance, low power and low cost, it can be variously used in a detection equipment of temperature environment.

Abstract: Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a functionalized layer contacted to either the base or the gate electrode. The functional layer can bind molecules, which causes an electrical signal in the sensor.

Abstract: The present disclosure provides a method for manufacturing a three-dimensional semiconductor memory device. In the method, a storage array is divided into a plurality of storage sub-arrays. As a result, a respective via of each storage sub-array can be etched respectively, which is different from the prior art, where a via for a bottom electrode of a plurality of layers of resistive cells is etched at one time. The vias are filled with metal so that storage sub-arrays are connected with each other. The method for manufacturing the three-dimensional semiconductor memory device according to the present disclosure can substantially reduce process complexity and difficulty of etching process in high-density integration, and also improve a number of layers of the resistive cells integrated in the storage array.

Abstract: A method, apparatus, system, and computer program products provides personal alert and tracking capabilities using one or more nodes. Each node includes radio transceiver chips operating at different frequency ranges, a power amplifier, sensors, a display, and embedded software. The chips enable the node to operate as either a mobile sensor node or a relay base station node while providing a long distance relay link between nodes. The power amplifier enables a line-of-sight communication between the one or more nodes. The sensors provide a GPS signal, temperature, and accelerometer information (used to trigger an alert condition). The embedded software captures and processes the sensor information, provides a multi-hop packet routing protocol to relay the sensor information to and receive alert information from a command center, and to display the alert information on the display.

Abstract: Data visualization methods, data visualization devices, data visualization apparatuses, and articles of manufacture are described according to some aspects.

Abstract: The present invention provides a process for preparing high melt strength propylene polymer by direct polymerization, comprising that a propylene polymer with wide molecular weight distribution and containing “very high molecular weight fraction” can be prepared by controlling the species and ratios of the external electron donors in the Ziegler-Natta catalyst system at different reaction stages according to the requirement for different molecular weight fractions in the different propylene polymerization stage of the series operation, and said polymer has excellent mechanical properties, especially with very high melt strength. The present invention also provides a propylene homopolymer with high melt strength, comprising the following features: (1) the MFR is 0.2-10 g/10 min at 230° C. with a load of 2.16 kg; (2) the molecular weight distribution Mw/Mn is 6-20; (3) the content of the fraction with a molecular weight higher than 5,000,000 is higher than or equal to 0.

Abstract: The present invention relates to novel iturin biosynthesis genes, and uses thereof. More specifically, the present invention provides novel iturin biosynthesis genes, wherein the iturin biosynthesis genes were cloned from Bacillus subtilis subsp. krictiensis ATCC 55079, the base sequence was determined after checking whether the cloned genes are iturin biosynthesis genes or not, and it was ascertained that the identified genes are novel genes different from the reported gene by comparing the base sequences with that of the reported gene, and uses thereof.

Abstract: A forging apparatus and method of uniformly heating, rheologically softening, and thermoplastically forming metallic glasses rapidly into a net shape using a rapid capacitor discharge forming (RCDF) tool are provided. The RCDF method utilizes the discharge of electrical energy stored in a capacitor to uniformly and rapidly heat a sample or charge of metallic glass alloy to a predetermined “process temperature” between the glass transition temperature of the amorphous material and the equilibrium melting point of the alloy in a time scale of several milliseconds or less. Once the sample is uniformly heated such that the entire sample block has a sufficiently low process viscosity it may be shaped into high quality amorphous bulk articles via forging in a time frame of less than 1 second.

Abstract: Disclosed is a method for the detection of radiation-induced damage on a biomaterial using a magnetic sensor, and a magnetic sensor biochip for biodosimetry. Designed to utilize a magnetic sensor in detecting damage to biomaterials in vitro, the method and magnetic sensor biochip can accurately determine the degree of damage irrespective of the self-recovery of the organism. Thanks to their high sensitivity, the method and biochip can detect the biomaterial damage by exposure to even a low dose of radiation.

Abstract: Disclosed herein is a debris-flow simulation apparatus having a variable flume. The flume includes a plurality of flume bodies which are connected to each other in the longitudinal direction. The heights of the flume bodies can be easily adjusted, thus varying the angles of inclination of the flume bodies.

Abstract: The present invention relates to compositions comprising a combination of PKC activators and PKC inhibitors and methods to modulate ?-secretase activity; improve or enhance cognitive ability; and/or reduce neurodegeneration in individuals suffering from diseases that impair cognitive ability, particularly Alzheimer's Disease. The invention also relates to methods for improving or enhancing cognitive ability. The present invention also provides methods for increasing the generation of non-amyloidogenic soluble APP (sAPP) comprising the activation of protein kinase C (PKC) in the brain and inhibiting PKC in peripheral tissues. Macrocyclic lactones (i.e. bryostatin class and neristatin class) are preferred PKC activators and Vitamin E is a preferred PKC inhibitor for use in the inventive composition.

Abstract: A magnesium halide adduct is provided, comprising at least one compound of the formula MgXY, at least one compound of the formula ROH, methanol, at least one modifying agent chosen from DOE and o-hydroxy benzoates, and optionally water. Also provided herein are a catalyst component comprising the magnesium halide adduct, a catalyst for olefin polymerization comprising the catalyst component; the respective processes for preparing the magnesium halide adduct and the catalyst component; use of the magnesium halide adduct for preparing the catalyst component, use of the catalyst component in a catalyst for olefin polymerization and use of the catalyst in olefin polymerization; and a process of olefin polymerization.

Abstract: A 3-axis magnetic field sensor on a substrate and including, a first tunneling magneto-resistor (TMR) having a first easy-axis for sensing a X-axis magnetic field, a second TMR having a second easy-axis for sensing a Y-axis magnetic field, an out-of-plane magnetic sensor for sensing a Z-axis magnetic field, and a reference unit is provided. The first easy-axis and the second easy-axis are orthogonal and include an angle of 45±5 degrees with a bisection direction, respectively. The out-of-plane magnetic sensor includes a groove or bulge structure having a first incline and a second incline; a third TMR on the first incline having a third easy-axis; a fourth TMR on the second incline having a fourth easy-axis; and a central axis orthogonal to the bisection direction and parallel to the third easy-axis and the fourth easy-axis. The reference unit has a fifth TMR and a fifth easy-axis parallel to the bisection direction.

Abstract: Provided is an optical module. The optical module includes: an optical bench having a first trench of a first depth and a second trench of a second depth that is lower than the first depth; a lens in the first trench of the optical bench; at least one semiconductor chip in the second trench of the optical bench; and a flexible printed circuit board covering an upper surface of the optical bench except for the first and second trenches, wherein the optical bench is a metal optical bench or a silicon optical bench.