Abstract: The purpose of the present invention is to develop: a method for selectively separating a glycoprotein derived from the central nervous system from a body fluid or a central nervous system cell; and a method for searching for an index marker for central nervous system diseases, which utilizes the aforementioned method. A protein derived from the central nervous system, which occurs in a trace amount in a body fluid or a central nervous system cell, can be selectively enriched by a two-stage separation procedure comprising removing a glycoprotein having sialic acid at a non-reducing terminal thereof from the body fluid or the central nervous system cell and then separating a glycoprotein having N-acetylglucosamine at a non-reducing terminal thereof.

Abstract: Provided are a composition for an anisotropic conductive adhesive, a method of forming a solder bump and a method of forming a flip chip using the same. The composition for an anisotropic conductive adhesive includes a low melting point solder particle and a thermo-curable polymer resin. The anisotropic conductive adhesive includes forming a mixture by mixing a polymer resin and a curing agent, and mixing a deforming agent, a catalyst or a reductant with the mixture.

Abstract: The invention relates to a novel class of self-assembling peptides, compositions thereof, methods for the preparation thereof and methods of use thereof. The invention also encompasses methods for tissue regeneration, increasing the production of extracellular matrix proteins, and methods of treatment comprising administering self-assembling peptides.

Abstract: Disclosed are nano multilayer film of electrical field modulation type, a field effect transistor of electrical field modulation type, an electrical field sensor of switch type, and a random access memory of electrical field drive type, for obtaining an electro-resistance effect in an electrical field modulation multilayer film at room temperature. The nano multilayer film comprises in succession from bottom to top a bottom layer (102), a substrate (101), a bottom layer (103), a functional layer (104), a buffer layer (105), an insulation layer (106), an intermediate conductive layer (107), and a cap layer (108), and the buffer layer (107) and the insulation layer (106) can be selectively added as required when the intermediate conductive layer (107) is a magnetic metal, a magnetic alloy or a magnetic metal composite layer.

Abstract: ?-Aminoamidine polymers and methods of preparing a-aminoamidine polymers by reacting by reacting one or more amines with one or more isocyanides and one or more aldehydes are described. Methods of preparing a-aminoamidine polymers from commercially available starting materials are also provided, wherein the starting materials are racemic or stereochemically pure. a-Aminoamidine polymers or salt forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems and for other purposes as well such as, for example, coatings, additives, excipients, plastics, and materials, etc. Given the amino moiety of these ?-aminoamidine polymers, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive ?-aminoamidine polymers and polynucleotides can be prepared. The inventive ?-aminoamidine polymers may also be used in preparing microparticles for drug delivery.

Abstract: A coniferyl alcohol or a Compositae family, Brassicaceae family, Umbelliferae family, Lamiaceae family, Liliaceae family or Amaranthaceae plant extract provides various uses associated with hTRPA1 activation, and, being a natural compound, involves relatively few side effects in the body and has substantial industrial applicability. The coniferyl alcohol or the Compositae family, Brassicaceae family, Umbelliferae family, Lamiaceae family, Liliaceae family or Amaranthaceae plant extract of the present invention not only will be a novel medical or food raw material which is helpful in maintaining homeostasis in the body associated with hTRPA1 activation, but can also be used to advantage in hTRPA1 antagonist screening.

Abstract: Digital focal plane arrays (DFPAs) with multiple counters per unit cell can be used to convert analog signals to digital data and to filter the digital data. Exemplary DFPAs include two-dimensional arrays of unit cells, where each unit cell is coupled to a corresponding photodetector in a photodetector array. Each unit cell converts photocurrent from its photodetector to a digital pulse train that is coupled to multiple counters in the unit cell. Each counter in each unit cell can be independently controlled to filter the pulse train by counting up or down and/or by transferring data as desired. For example, a unit cell may perform in-phase/quadrature filtering of homodyne- or heterodyne-detected photocurrent with two counters: a first counter toggled between increment and decrement modes with an in-phase signal and a second counter toggled between increment and decrement modes with a quadrature signal.

Abstract: The present invention relates to heterocyclic compounds (e.g., compounds described by Formula (I)) and pharmaceutically acceptable salts thereof. The invention also features pharmaceutical compositions that include these compounds and their use in therapy for treating conditions in which necroptosis is likely to play a substantial role. The heterocyclic compounds described herein can also achieve improved activity and selectivity towards RIP1 and/or RIP3.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to EGFR on tumor cells that overexpress EGFR, and on tumor cells that express the truncated version of the EGFR receptor, de2-7 EGF. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: The present disclosure generally relates to protein binding agents, such as protein kinase binding agents of general Formula (I). The protein binding agents may be provided attached to a solid support and may be used, for example, to detect the presence of a broad range of proteins in a sample. Methods of synthesizing the protein binding agents, and kits comprising the protein binding agents, are also disclosed.

Abstract: The method for redundancy of a wireless communication network according to the embodiment of the present invention includes: partitioning the same frequency band of a first base station transceiver subsystem and a second base station transceiver subsystem, which form redundant cell coverage, into a plurality of resource blocks; partitioning each of the partitioned resource blocks into a first frequency partition (FP) and a second frequency partition which are configured to have the same structure as each other; and transmitting and receiving, by the first base station transceiver subsystem, data using a first resource block allocated to the first frequency partition and by the second base station transceiver subsystem, data using a second resource block allocated to the second frequency partition.

Abstract: The present invention provides a method for synthesizing a BixSb2-xTe3 thermoelectric nanocompound (0<x<2), comprising the following steps: preparing a Bi—Sb—Te solution by adding Bi, Sb, and Te precursors to a solvent (step 1); preparing a Bi—Sb—Te hydrate by mixing the Bi—Sb—Te solution prepared in step 1) with a base aqueous solution (step 2); preparing a BixSb2-xTe3 reactant by liquid phase reduction at room temperature after adding a reducing agent to the Bi—Sb—Te hydrate prepared in step 2) (step 3); aging the BixSb2-xTe3 reactant prepared in step 3) (step 4); and preparing BixSb2-xTe3 nanoparticles by filtering and drying the BixSb2-xTe3 reactant aged in step 4) (step 5). The BixSb2-xTe3 thermoelectric nanocompound synthesized by the method of the present invention via liquid phase reduction is composed of regular nanoparticles since the method does not need any additional heat-treatment to eliminate chemical additives and prevents particles from being over-grown.

Abstract: A biological tissue cutting and fluid aspiration system provides a plurality of surgical instruments operable independent of an external control console. In some embodiments, each surgical instrument may include all sensors and controls directly applicable to the surgical instrument, and may be used independently. In some embodiments, instruments communicate status information to each other, and adjust operating parameters based on the communications.

Abstract: There is described herein a method of enriching a population of stem cells for hematopoietic progenitors. The method comprises inducing hematopoietic differentiation in a population of human embryonic stem cells or human induced pluripotent stem cells; sorting the population based on expression of CD43 and at least one of CD34, CD31 and CD144; and selecting a fraction that is at least one of CD34+CD43?, CD31+CD43? and CD144+CD43?. Also provided are populations of hematopoietic progenitors obtained by the methods described herein.

Abstract: The disclosure provides a filtration material and a method for fabricating the same. The filtration material includes a supporting layer, and a composite layer, wherein the composite layer includes an ionic polymer and an interfacial polymer. Particularly, the ionic polymer and the interfacial polymer are intertwined with each other, resulting from ionic bonds formed between the ionic polymer and the interfacial polymer.

Abstract: A photoactive article includes a substrate including a semiconductor to absorb light and to produce a plurality of charge carriers; a dielectric layer disposed on the substrate; a conductive member disposed on the dielectric layer and opposing the substrate such that the dielectric layer is exposed by the conductive member, the conductive member to receive a portion of the plurality of charge carriers from the substrate; and an electrolyte disposed on the dielectric layer and the conductive member. Making a photoactive article includes forming a dielectric layer on a substrate by rapid thermal oxidation, the dielectric layer comprising an oxide of a semiconductor; and forming a conductive member disposed on the dielectric layer.

Abstract: Technologies are generally described for detecting diseased tissues through fiber optic based Raman spectroscopy, image acquisition, and/or RF induced hyperthermia treatment of the detected tissues in an integrated manner. A fiber optic bundle for carrying optical and RF signals for the spectroscopy, visual imaging, and RF ablation may also be used to detect a temperature of the treated tissue such that level and duration of the RF signal can be controlled for optimum results. A shielding configuration in the form of a coaxial waveguide of the fiber optic bundle may be used to guide and deliver the RF signal. Sources and detectors for the optical and RF signals may be integrated into an endoscopic probe containing the fiber optic bundle or be externally positioned. An integrated or remote controller may be employed to manage the optical imaging, spectroscopy, RF ablation, and thermal sensing operations.

Abstract: A language learning system including a storage module, a feature extraction module, and an assessment and diagnosis module is provided. The storage module stores training data and an assessment decision tree generated according to the training data. The feature extraction module extracts pronunciation features of a pronunciation given by a language learner. The assessment and diagnosis module identifies a diagnosis path corresponding to the pronunciation of the language learner in the assessment decision tree and outputs feedback information corresponding to the diagnosis path. Thereby, the language learning system can assess and provide feedback information regarding words, phrases or sentences pronounced by the language learner.

Abstract: The main object of the invention is to provide an electromagnetic wave resonator making use of surface waves: an electromagnetic wave resonator structure capable of being achieved with existing technologies yet without much difficulty and applying voltage to a positive dielectric area, thereby overcoming a variety of problems arising from the fact that only thermal excitation is available. The contact structure of negative dielectric/positive dielectric/negative dielectric necessary for this type of electromagnetic wave resonator is provided on the surface of the negative dielectric material 1 just as the coaxial structure of the positive dielectric thin film 3 extending in the Y-axis direction and the negative dielectric material 2 received therein is cut in the axial direction.

Abstract: Disclosed are an apparatus and a method for extracting a foreground layer from an image sequence that extract a foreground object layer area in which a depth value is discontinuous with that of a background from an input image sequence. By using the present disclosure, the layer area is automatically tracked in the subsequent frames through user's setting in the start frame in the image sequence in which the depth values of the foreground and the background are discontinuous, thereby extracting the foreground layer area in which the drift phenomenon and the flickering phenomenon are reduced.