Patents Assigned to INSTITUTE
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Publication number: 20140270458Abstract: Devices, systems, and methods are disclosed for determining the number and type of blood cells in a blood sample. The blood sample is collected and held in a slide. In the slide, the blood sample is separated and channeled into at least two sampling chambers, one for red blood cells, another for white blood cells, and optionally yet another for platelets. The sampling chambers have wetting agents, lysing agents, staining agents, or the like therein to mix with the blood and facilitate cell count. The slide is placed in a portable slide analyzer where the sampling chambers are illuminated and images of the sampling chambers are taken. These images are converted into electronic form and sent by a communications module of the slide analyzer to a remote external location where the images are analyzed to determine the number and type of blood cells in the blood sample.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicants: The Regents of The University of California, Tahoe Institute for Rural Health Research, LLCInventors: Zachary Smith, Tingjuan Gao, Stephen Lane, Sebastian Wachmann-Hogiu, Denis Dwyre, Laurence Heifetz, James Hood, Dennis Matthews, Keith Tatsukawa
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Publication number: 20140275683Abstract: Disclosed is a catalyst for preparing isobutene by dissociation of methyl tert-butyl ether, the catalyst comprising amorphous silica alumina and a silicalite-1 molecular sieve, wherein the total IR acid amount of weak acids in the catalyst is in a range from 0.020 to 0.080 mmol/g, and the ratio of B acid/L acid of the weak acids is in a range from 2.5:1 to 4.0:1. Also provided is a method of preparing the catalyst and the use thereof. The catalyst has a high selectivity with respect to isobutene, and high conversion of methyl tert-butyl ether, and can also effectively inhibit formation of the by-product dimethyl ether.Type: ApplicationFiled: October 24, 2012Publication date: September 18, 2014Applicants: CHINA PETROLEUM & CHEMICAL CORPORATION, FUSHUN RESEARCH INSTITUTE OF PETROLEUM AND PETROCHEMICALS, SINOPECInventors: Shumei Zhang, Kai Qiao, Ming Chen, Qingtong Zhai, Changxin Guo, Chunmei Wang
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Publication number: 20140273222Abstract: In one embodiment, a bioreactor includes a cartridge adapted to deliver growth media to inner and outer surfaces of a tubular organ scaffold, the cartridge having a container that includes a first passage adapted to deliver a first growth medium to the inner surfaces of the tubular organ scaffold and a second passage adapted to deliver a second growth medium to the outer surfaces of the scaffold, wherein the first and second growth media are different media.Type: ApplicationFiled: March 17, 2014Publication date: September 18, 2014Applicant: GEORGIA REGENTS RESEARCH INSTITUTE, INC.Inventors: Paul Weinberger, Hunter Faircloth, Donald Mettenburg, Frederick Rueggeberg
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Publication number: 20140278062Abstract: The present invention relates to a navigation system for preventing an airplane or a ship carrying freight and passengers from becoming involved in an accident with other transport means. To this end, the navigation system of the present invention includes: a GPS module for obtaining position information on first transport means; an information searching module for searching second transport means positioned a predetermined distance away from the first transport means with reference to the position information and operation schedule of the first transport means; a path creating module for creating a secure path for the first transport means with reference to information on an operation path according to the operation schedules and the position information on the first and second transport means; and a display module for displaying the position information on the first and second transport means.Type: ApplicationFiled: April 20, 2012Publication date: September 18, 2014Applicant: THE KOREA TRANSPORT INSTITUTEInventors: Jae Hyun Han, Seung Ho Lee, You Chul Hwang
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Publication number: 20140263036Abstract: A flexible porous free-standing protein membrane includes cross-linked protein. At least part of pores of the porous membrane is formed by removing nanostrands whose diameters are 2-3 nm, the cross-linked protein is cross-linked by a bifunctional cross-linker, and a thickness of the protein membrane is 10 ?m or less.Type: ApplicationFiled: May 29, 2014Publication date: September 18, 2014Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: XinShen PENG, Izumi ICHINOSE
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Publication number: 20140271060Abstract: A feed mechanism to feed objects for insertion into tobacco industry products including a rotary member for receiving objects, the rotary member having a plurality of channels, each channel being adapted so that in use objects assemble in a row in the channel which rotates with the rotary member, each channel having an outlet for dispensing an object from the channel, and a pneumatic mechanism configured to hold an object in a row prior to the object being dispensed.Type: ApplicationFiled: May 29, 2014Publication date: September 18, 2014Applicant: Tobacco Research and Development Institute (Proprietary) LimitedInventor: Gerhard LE ROUX
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Publication number: 20140272993Abstract: The present invention provides methods of purifying RNA from a biological sample comprising two separate aqueous extractions of the organic phase obtained by mixing the biological sample with a first solution comprising guanidinium isothiocyanate and beta-mercaptoethanol and a second solution comprising phenol, chloroform, and isoamyl alcohol. Also provided are methods of sequencing RNA purified from a biological sample and methods of diagnosing Alzheimer's disease and Parkinson's disease in a subject by determining whether a plurality of miRNAs has deregulated expression in biological sample from the subject.Type: ApplicationFiled: March 15, 2014Publication date: September 18, 2014Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTEInventors: Kendall Van Keuren-Jensen, Kasandra L. Burgos
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Publication number: 20140280454Abstract: Distributed content caching is implemented in an efficient, low cost manner within a content delivery network (CDN). In various embodiments, content is identified for caching at a number of gateway devices within a CDN by minimizing a cost function associated with content delivery in the network. The cost function may take into consideration costs of delivering content to users from gateway devices as well as costs associated with delivering content to users from centralized locations of a CDN.Type: ApplicationFiled: November 22, 2013Publication date: September 18, 2014Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Muriel Medard, Flavio du Pin Calmon, Weifei Zeng
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Publication number: 20140272643Abstract: A reactor containing a heat exchanger is disclosed, which can be operated with co-current or counter-current flow. Also disclosed is a system that includes a reactor having a reformer and a vaporizer, a fuel supply, and a water supply. The reactor includes a source of combustion gas, a reformer operative to receive reformate, and a vaporizer operative to receive water. The reformer and vaporizer each include a stack assembly formed by a combination of separator shims and channel shims. The separator shims and channel shims are stacked in a regular pattern to form two sets of channels within the stack assembly. One set of channels will have vertical passageways at either end and a horizontal flowpath between them, while the other set of channels has only a horizontal flowpath.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: Battelle Memorial InstituteInventors: Paul E. George, II, Vincent Contini, Matthew E. Goshe
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Publication number: 20140271667Abstract: A method for inhibiting tumor cell migration or metastasis of a cancer in a mammalian subject comprises one or more of the steps of administering to a subject a therapeutically effective amount of a composition comprising a molecule that: suppresses focal adhesion kinase (FAK) activity or phosphorylation; suppresses ULK1 kinase activity; suppresses activation or signaling of the mTORC1 (Ser757) pathway; activates AMPK; activates FIP200; or activates LKB1, in a cancer cell. Still another method of inhibiting tumor cell migration involves inhibiting phosphorylation of ULK1 on Ser757 in subjects with lung cancer. Suppressing activation or signaling of the mTORC1 (Ser757) pathway in subjects is in one aspect useful in treating lung cancer.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: The Wistar Institute of Anatomy and BiologyInventors: Dario C. Altieri, Young Chan Chae
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Publication number: 20140271488Abstract: Synthesis of compounds having varying degrees of conformational rigidity is obtained via a low cost, high yield and efficient synthetic reactions. The library of compounds is structurally diverse having at least one or more chiral centers and providing large numbers of compounds having building block diversity and substantial scaffold diversity. The compounds further provide a novel method for obtaining candidate therapeutic agents for prevention, treatment or diagnosis of diseases.Type: ApplicationFiled: September 7, 2012Publication date: September 18, 2014Applicant: The Scripps Research InstituteInventors: Glenn C. Micalizio, Thomas Kodadek, Mohosin Sarkar
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Publication number: 20140280330Abstract: A method of performing a query on a cube of data is provided. A cube of data is distributed onto a plurality of computing devices with each computing device of the plurality of computing devices storing a different portion of the cube of data. A perturbation rule configured for application to the cube of data and associated with a user is received. A process space associated with the user is created. The received perturbation rule is compiled in association with the created process space. A query on the portion of the cube of data stored at the computing device is received. The received query is associated with the created process space. The query is processed while applying the compiled perturbation rule to data extracted from the portion of the cube of data stored at the computing device. A result of the processed query is sent to a requesting computing device.Type: ApplicationFiled: July 24, 2013Publication date: September 18, 2014Applicant: SAS Institute Inc.Inventors: Stacey M. Christian, Donald James Erdman, Scott T. Gray
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Publication number: 20140282799Abstract: The present invention relates to a method for transmitting media data via a heterogeneous IP network, the method efficiently transmitting, independently of a specific media codec, media streaming in the format of a coded media fragment data unit, including a header of a media unit having a minimized size and a simplified structure.Type: ApplicationFiled: October 12, 2012Publication date: September 18, 2014Applicant: Electronics and Telecommunications Research InstituteInventor: Seong Jun Bae
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Publication number: 20140282856Abstract: This disclosure describes methods, systems, and computer-program products for determining classification rules to use within a fraud detection system The classification rules are determined by accessing distributional data representing a distribution of historical transactional events over a multivariate observational sample space defined with respect to multiple transactional variables. Each of the transactional events is represented by data with respect to each of the variables, and the distributional data is organized with respect to multi-dimensional subspaces of the sample space. A classification rule that references at least one of the subspaces is accessed, and the rule is modified using local optimization applied using the distributional data. A pending transaction is classified based on the modified classification rule and the transactional data.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Applicant: SAS Institute Inc.Inventors: Brian Lee Duke, Vijay S. Desai, Paul C. Dulany, Kannan Shashank Shah
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Publication number: 20140278447Abstract: A digital watermark detection device includes a first chirp z-transform unit (202a) and a second chirp z-transform unit (202b) for estimating the cochlear delay characteristics simulated by cochlear delay filters that were used in embedding digital watermark data in an acoustic signal. The digital watermark data embedded in the acoustic signal is detected based on the cochlear delay characteristics estimated in accordance with the result of chirp z-transform applied by these first chirp z-transform unit (202a) and second chirp z-transform unit (202b).Type: ApplicationFiled: August 22, 2012Publication date: September 18, 2014Applicant: Japan Advanced Institute of Science and TechnologyInventors: Masashi Unoki, Ryota Miyauchi, Toshizo Kosugi
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Publication number: 20140271652Abstract: Disclosed are immunomodulatory polypeptides that elicit an unusual induced cytokine profile, compositions comprising such polypeptides, compositions comprising antibodies that specifically bind to such polypeptides, and methods of using the same, including in cancer treatment, in the treatment of autoimmune diseases, in organ transplantation and for reducing graft rejection, for promoting fertility, and for identifying a neutrophil subset and/or other cellular subset including by flow cytometry. Pharmaceutical compositions and kits, and treatment methods are also disclosed.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: Institute of Arthritis Research, LLCInventor: Craig D. Scoville
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Publication number: 20140275268Abstract: Novel solid forms of tacedinaline (4-(acetylamino)-N-(2-aminophenyl)benzamide), including crystalline tacedinaline Form B, a novel crystalline tacedinaline TFA salt, and amorphous tacedinaline, are disclosed. Pharmaceutical compositions comprising crystalline tacedinaline Form B, the novel crystalline tacedinaline TFA salt, and/or amorphous tacedinaline, and methods of treating various conditions by administering those novel solid forms, are also disclosed.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: THE BROAD INSTITUTE, INC.Inventors: Edward Holson, Florence F. Wagner, G. Patrick Stahly
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Publication number: 20140280220Abstract: A method of determining a storage device on which to store received data is provided. Data is received. A score indicating a value associated with the received data is computed. A storage device is determined from a plurality of types of storage devices on which to store the received data based on the computed score. The received data is sent to the determined storage device.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: SAS Institute Inc.Inventors: Gary Spakes, Scott Meredith Chastain, Bryan Christopher Harris
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Publication number: 20140282246Abstract: Various embodiments are generally directed to techniques for increasing the accuracy with which list items may be selected on a touch screen. A machine-readable storage medium includes instructions that when executed cause a computing device to present a list of multiple list items on a touch screen, each associated with a touch area and including a wide area marking a location of the touch area and a narrow area narrower than the wide area, the wide and narrow areas defining a presentation area wherein the wide areas of adjacent first and second list items are positioned at different first and second widthwise positions, respectively, and wherein the touch areas of the first and second list items coincide with the wide areas of the first and second list items, respectively. Other embodiments are described and claimed.Type: ApplicationFiled: February 11, 2014Publication date: September 18, 2014Applicant: SAS Institute Inc.Inventors: Qing Gong, Huifang Wang
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Publication number: 20140276454Abstract: Embodiments for superficial tissue compliance modulation and negative pressure wound therapy for stabilization of a chronic percutaneous implant are disclosed. An external cap is coupled to a compliance gradient of progressively decreasing stiffness. Together the external cap and compliance gradient act as a stress shield that allows forces that would otherwise act on the skin at the skin-implant interface to be dissipated over a larger area. In addition, negative pressure and fluids may be applied through negative pressure and fluid adapters, respectively, to the skin-implant interface, the status of which may be further monitored through the use of one or more sensors.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Rehabilitation Institute of ChicagoInventors: Todd A. Kuiken, Gregory A. Dumanian, Jason M. Souza
