Abstract: Disclosed herein are methods of determining the sequence and/or positions of modified bases in a nucleic acid sample present in a circular molecule with a nucleic acid insert of known sequence comprising obtaining sequence data of at least two insert-sample units. In some embodiments, the methods comprise obtaining sequence data using circular pair-locked molecules. In some embodiments, the methods comprise calculating scores of sequences of the nucleic acid inserts by comparing the sequences to the known sequence of the nucleic acid insert, and accepting or rejecting repeats of the sequence of the nucleic acid sample according to the scores of one or both of the sequences of the inserts immediately upstream or downstream of the repeats of the sequence of the nucleic acid sample.
Type:
Grant
Filed:
June 8, 2012
Date of Patent:
March 18, 2014
Assignee:
Industrial Technology Research Institute
Abstract: An electrochemical device having a liquid electrolyte which includes a protic solvent, an anode electrode disposed in contact with the liquid electrolyte, and a cathode electrode disposed in contact with the liquid electrolyte. A membrane which interrupts the transport of ions between the electrodes at a predetermined temperature is disposed in the liquid electrolyte between the anode electrode and the cathode electrode. In this way, electrochemical devices such as batteries, fuel cells, electrolyzers, and sensors, which may overheat during use and cause a fire or explosion, are precluded from overheating.
Abstract: A process for production of fermentable sugars from biomass using multi-enzyme multi-step system is provided herein. The process disclosed in the present invention provides high yielded sugars in less time period. The multi-enzyme system disclosed in the present invention converts celluloses, hemicelluloses and/or mixture thereof to fermentable sugar with higher efficiency and better economics than the process known in the prior art. Cellulose and hemicelluloses fractions derived from natural sources such as any lignocellulosic biomass are saccharified in a shortened time with higher conversion rates of intermediates with modified enzymatic compositions/groups of the Multi-enzyme system to enhance the rate thus providing an economical cellulose and hemicellulose saccharification process.
Type:
Grant
Filed:
November 20, 2012
Date of Patent:
March 18, 2014
Assignee:
Chemical Engineering Department, Institute of Chemical Technology (Deemed University)
Abstract: Examples are disclosed for forwarding cells of partitioned data through a three-stage memory-memory-memory (MMM) input-queued Clos-network (IQC) packet switch. In some examples, each module of the three-stage MMM IQC packet switch includes a virtual queue and a manager that are configured in cooperation with one another to forward a cell from among cells of partitioned data through at least a portion of the switch. The cells of partitioned data may have been partitioned and stored at an input port for the switch and have a destination of an output port for the switch.
Abstract: A method of determining a transmitted vector (x) in a MIMO receiver includes the steps of receiving a received vector (y) representative of the transmitted vector (x), generating a first random number and forming, in a first iteration, a first symbol of a first candidate vector, the candidate vector representing a potential solution vector. The step of forming is based on a first approach if the first random number is greater than a first predetermined value (q), but is based on a second approach if the random number is less than or equal to the first predetermined value (q). The first approach randomly selects the first symbol from a uniform distribution of symbols in the transmission alphabet. The second approach selects the first symbol based on Gibbs sampling. The method represents a randomized Markov Chain Monte Carlo (RMCMC) sampling technique.
Abstract: Disclosed are a method and apparatus for providing metadata for a sensory effect, a computer-readable recording medium on which metadata for a sensory effect are recorded, and a method and apparatus for reproducing a sensory effect. A method for providing metadata for a sensory effect includes generating Sensory Effect Metadata (SEM) including sensory effect information on contents using binary representation syntax; and analyzing the SEM and transmitting the SEM to a sensory reproduction apparatus engine unit that generates control information on a sensory reproduction apparatus. In the method, the sensory effect information includes color correction effect information on the contents.
Type:
Grant
Filed:
April 1, 2011
Date of Patent:
March 18, 2014
Assignee:
Electronics and Telecommunications Research Institute
Abstract: The present invention relates to nanostructured material capable of storing hydrogen. The nanostructured material may be configured with a selected geometry to provide the capability to influence and increase the limiting or theoretical gravimetric storage level (GSL) of hydrogen for a given chemical composition.
Type:
Grant
Filed:
December 22, 2006
Date of Patent:
March 18, 2014
Assignee:
Southwest Research Institute
Inventors:
Michael A. Miller, Kent Edward Coulter, James H. Arps
Abstract: Embodiments of the present invention include apparatuses, systems and methods for multi-patch based super-resolution from a single video frame. Such embodiments include a scale-invariant self-similarity (SiSS) based super-resolution method. Instead of searching HR examples in a database or in LR image, the present embodiments may select the patches according to the SiSS characteristics of the patch itself, so that the computational complexity of the method may be reduced because there is not any search involved. To solve the problem of lack of relevant examples in natural images, the present embodiments may employ multi-shaped and multi-sized patches in HR image reconstruction. Additionally, embodiments may include steps for a hybrid weighing method for suppressing artifacts. Advantageously, certain embodiments of the method may be 10˜1,000 times faster than the example based SR approaches using patch searching and can achieve comparable HR image quality.
Type:
Grant
Filed:
September 28, 2012
Date of Patent:
March 18, 2014
Assignee:
Hong Kong Applied Science and Technology Research Institute Co., Ltd.
Inventors:
Luhong Liang, King Hung Chiu, Edmund Y. Lam
Abstract: The present invention relates to methods and products associated with in vivo enzyme profiling. In particular, the invention relates to methods of in vivo processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. The invention also relates to products, kits, and databases for use in the methods of the invention.
Type:
Grant
Filed:
March 2, 2010
Date of Patent:
March 18, 2014
Assignee:
Massachusetts Institute of Technology
Inventors:
Sangeeta N. Bhatia, Geoffrey A. von Maltzahn, Gabriel Kwong
Abstract: Sets, kits or stocks of anti-myopia contact or spectacle lenses, along with methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Extensive surveys have shown that lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than ?6 D central refractive error. In one example, a kit or set of lenses (50, FIG. 15) can have multiple parts or sub-sets (52, 54) each comprising a compartmented container (56a, 56b) with lenses (58a, 58b) arranged according to increments of central corrective power (59a, 59b). The lenses (58a) of the first part (52) have four steps (60a, 61a, 62a, 64a) of peripheral power or defocus to pro vide therapeutic effect and, while the lenses (58b) of the second part (54) also have four steps (60b, 61b, 62b, 64b), the level of therapeutic effect is higher.
Type:
Grant
Filed:
April 20, 2009
Date of Patent:
March 18, 2014
Assignees:
Novartis AG, Brien Holden Vision Institute
Inventors:
Aldo Abraham Martinez, Arthur Ho, Padmaja Rajagopal Sankaridurg, Percy Fabian Lazon, Brien Anthony Holden, Rick Payor, Gregor F. Schmid
Abstract: Computer-implemented systems and methods are provided to perform accuracy analysis with respect to forecasting models, wherein the forecasting models provide predictions based upon a pool of production data. As an example, a forecast accuracy monitoring system is provided to monitor the accuracy of the forecasting models over time based upon the pool of production data. A forecast model construction system builds and rebuilds the forecasting models based upon the pool of production data.
Abstract: Methods and therapeutic agents are disclosed for treating neurodegenerative disorders by depletion of CD8 positive T cells by using antibodies, FAb fragments of antibodies or similar agents that sequester, neutralize or deplete the CD8+ cytotoxic T cells.
Type:
Grant
Filed:
February 23, 2012
Date of Patent:
March 18, 2014
Assignee:
ALS Therapy Development Institute
Inventors:
Steven Perrin, John Lincecum, Alan Gill, Fernando Vieira
Abstract: Disclosed herein is a method for preparing a ceramic waste form containing radioactive rare-earth and transuranic oxide, and the ceramic waste form with enhanced density, heat-stability, and leach resistance prepared by the same.
Type:
Grant
Filed:
June 11, 2010
Date of Patent:
March 18, 2014
Assignee:
Korea Atomic Energy Research Institute Korea Hydro & Nuclear Power Co., Ltd.
Inventors:
Byung-Gil Ahn, Hwan-Seo Park, Hwan-young Kim, In-Tae Kim, Hansoo Lee
Abstract: A direct current to direct current converter includes: an input terminal; an output terminal having voltage higher than the input terminal; a coupled inductor boost cell including a coupled inductor connected to the input terminal, a switch connected to the coupled inductor, and an output diode connected to the output terminal; and a clamp and energy transfer cell including a clamp diode connected to the coupled inductor, a clamp capacitor connected to the clamp diode, and an energy transfer diode connected to the output diode.
Type:
Grant
Filed:
March 9, 2012
Date of Patent:
March 18, 2014
Assignees:
Samsung Display Co., Ltd., Korea Advanced Institute of Science and Technology
Inventors:
Won Sik Oh, Gun Woo Moon, Shin Young Cho, Dae Youn Cho
Abstract: Provided is a method of forming a fine pattern of a polymer thin film using a phenomenon that another material having a large difference in surface energy in comparison with a polymer thin film pattern is dewetted on the polymer thin film pattern. Two polymer materials having a large difference in surface energy can be applied to readily and conveniently form a fine pattern of a polymer thin film of micrometer or sub-micrometer grade.
Type:
Grant
Filed:
August 17, 2009
Date of Patent:
March 18, 2014
Assignee:
Electronics and Telecommunications Research Institute
Inventors:
Seong Hyun Kim, Sang Chul Lim, Yong Suk Yang, Zin Sig Kim, Doo Hyeb Youn
Abstract: An electromagnetic transmission apparatus comprises a plurality of electromagnetic coupling elements, wherein each electromagnetic coupling element has at least one resonant structure. The plurality of electromagnetic coupling elements are arranged that when the electromagnetic transmission apparatus is operated within a specific frequency band, an electromagnetic coupling device near the electromagnetic transmission apparatus within an electromagnetic distance can electromagnetically couple with the electromagnetic transmission apparatus by near-field coupling, and the electromagnetic wave of the electromagnetically coupling propagates along with the arrangement direction of the plurality of electromagnetic coupling elements.
Type:
Grant
Filed:
April 12, 2011
Date of Patent:
March 18, 2014
Assignee:
Industrial Technology Research Institute
Inventors:
Ta Chun Pu, Chun Yih Wu, Hung Hsuan Lin
Abstract: Computer-implemented systems and methods are provided for processing a multi-dimensional data structure. For example, systems and methods are provided for processing the multi-dimensional data structure and allowing cell selection rules related to the multi-dimensional data structure to be resolved efficiently, so that computational cost associated with processing the multi-dimensional data structure can be saved.
Abstract: Disclosed herein is a flexible short pipe having a shock absorbing function. The flexible short pipe has flexibility so as to absorb shocks generated in the longitudinal direction of a lifting pipe (or flexible pipe) and have resistance to a bending load or a torsional load when being wound around a roller. The flexible short pipe includes flanges provided at upper and lower ends thereof to be coupled to a unit lifting pipe or flexible pipe. An inner layer has a curved shape and is provided between the upper and lower flanges to allow slurry, lifted up or discharged by a lifting pump, to flow along the inner layer. An outer layer has a curved shape and surrounds the inner layer. A shock absorbing means is positioned between the inner layer and the outer layer, and absorbs longitudinal force and bending force.
Type:
Grant
Filed:
April 15, 2010
Date of Patent:
March 18, 2014
Assignee:
Korea Institute of Geoscience and Mineral Resources (KIGAM)
Inventors:
Chi-Ho Yoon, Byung-Sik Ahn, Jong-Myung Park
Abstract: The present disclosure provides a mirror device with illumination comprising a transparent conductive substrate, an isolation layer, a mirror layer and a light emitting diode (LED) layer. The isolation layer, formed on a surface of the transparent conductive substrate, divides the surface of the transparent conductive substrate into at least one first region and at least one second region. The mirror layer formed on the transparent conductive substrate within the at least one first region, while the LED layer is formed on the transparent conductive substrate within the at least one second region, wherein the mirror layer and the LED layer are electrically isolated from each other. In another embodiment, the present disclosure further provides a mirror box having the mirror device with illumination disposed therein so that the mirror device can be easily carried and kept in the pocket, or purse of user.
Type:
Grant
Filed:
April 27, 2012
Date of Patent:
March 18, 2014
Assignee:
Industrial Technology Research Institute