Abstract: The present disclosure provides a method and system for improving a counting rate of a superconducting nanowire single photon detector. The method includes: coupling an electrical attenuator in series with an output end of the superconducting nanowire single photon detector; the electrical attenuator includes an input end and an output end, and the input end of the electrical attenuator is coupled with the output end of the superconducting nanowire single photon detector. The present disclosure couples the electrical attenuator in series with the output end of the superconducting nanowire single photon detector. Since the configuration of the electrical attenuator is a resistor network, it can act as a series resistor and can also reduce the response pulse amplitude of the superconducting nanowire single photon detector. The present disclosure can improve the counting rate of the superconducting nanowire single photon detector, while keeping the detection efficiency high.

Abstract: Anti-GAL9 antibody constructs, pharmaceutical compositions comprising the constructs, and methods of use thereof are presented.

Abstract: An antenna apparatus may be disclosed. The antenna apparatus may include a feed network including a plurality of first internal transmission lines arranged in a cross form and a plurality of second internal transmission lines arranged in a ring form around the plurality of first internal transmission lines; and a plurality of radiation elements positioned around the feed network and radiating signals fed by the feed network.

Abstract: Provided is a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; a pharmaceutical composition for the prevention or treatment of Sirt6-associated diseases, including as an active ingredient, a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; and a method for treating Sirt6-associated diseases including administering a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof to a subject in need.

Abstract: A device and a method for physical characterization in a large-scale natural gas hydrate experimental system are provided. The device includes a reactor, horizontal wellbores, and vertical wellbores. The reactor includes an upper cover, a lower cover, and a reactor body, and the upper cover and the lower cover are sealably attached to two ends of the reactor to form a closed chamber. The physical characterization device further includes lateral vertical well assemblies and temperature-pressure-resistance assemblies, wherein the lateral vertical well assemblies and the temperature-pressure-resistance assemblies are disposed to penetrate the reactor from the upper cover to the lower cover. The physical characterization method is conducted using the physical characterization device, including a step of producing contour plots using a data processing software with three-dimensional matrix data collected by the pressure measuring tubes, the temperature measuring tubes, and the resistivity measuring columns.

Abstract: A method in which a high-quality packet telephony terminal apparatus performing low-latency and lossless packet communication with a counterpart packet telephony terminal apparatus operates in an integrated network structure in which a time sensitive network (TSN) and a packet communication network are combined may be disclosed. The packet telephony terminal apparatus may perform packet telephony call processing, perform a TSN stream reservation procedure when the counterpart packet telephony terminal apparatus is capable of performing a TSN function for lossless packet communication, adjust a size of a dejitter buffer when the TSN stream reservation procedure is successful, and perform low-latency packet telephony communication through the minimized size of the dejitter buffer.

Abstract: A non-contact muscle signal sensing and assisting device, comprises a radar sensing module, a microprocessor and an electrical stimulation module. The radar sensing module continuously transmits a first microwave signal to a muscle bundle part and receives a corresponding reflected muscle signal, and performs a demodulation procedure on a second microwave signal and the reflected muscle signal to obtain and output a demodulated muscle signal. The microprocessor performs a muscle-movement signal characteristic processing procedure on the demodulated muscle signal to obtain a characterized muscle signal. The microprocessor obtains a muscle movement parameter according to the characterized muscle signal and controls the electrical stimulation module to emit a micro electrical stimulation signal to stimulate a reflex nerve when the muscle movement parameter fits an assistive condition, thereby stimulate muscle movement.

Abstract: Disclosed is a catalyst for hydrogen evolution reaction (HER) including: a first transition metal matrix; and a second transition metal oxide formed on the first transition metal matrix; wherein a hydroxyl group is introduced on the second transition metal oxide.

Abstract: The present disclosure relates to methods aimed towards non-invasive targeted genomic and epigenomic sequencing of spatially-defined cellular or subcellular region. More particularly, the present disclosure relates to methods of using photoselection to achieve non-invasive targeted genomic and epigenomic sequencing of spatially-defined cellular or subcellular regions, via the use of light-activated probes.

Abstract: Disclosed are a heterogeneously integrated optical modulator and a manufacturing method thereof. The modulator includes a substrate having a trench, an input waveguide disposed at one side of the trench, an output waveguide disposed at the other side of the trench, a first Mach-Zehnder interferometer including first branch waveguides disposed between the input waveguide and the output waveguide and a heater disposed on one of the first branch waveguides, and second Mach-Zehnder interferometers connected to each of the first branch waveguides.

Abstract: The present disclosure relates to a pharmaceutical composition comprising a nucleic acid molecule of an adjuvant, a metal complex stabilizing the nucleic acid molecule, and optionally an immunogen that may be a peptide or a protein, or a composition of stabilizing the nucleic acid molecule of the adjuvant comprising the metal complex. The metal complex interacts with the nucleic acid molecule of the adjuvant and/or the immunogen so as to stabilize such pharmaceutically active ingredients, and induces continuous effectiveness of the active ingredients without degradation.

Abstract: The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.

Abstract: Improvement is made in performance of a trained neural network that uses positional information indicating a position at which each token included in an input sequence is present in the input sequence.

Abstract: The present invention relates to a method for analyzing a biological sample obtained from a subject, comprising analyzing components contained in a biological sample by an assay using a first molecule selected from the group consisting of a molecule binding to a sugar chain bindable with BC2LCN, a molecule binding to SerpinA3, and a molecule binding to Gal3BP, and a second molecule that is BC2LCN.

Abstract: A comprehensive three-dimensional exploitation experimental system for large-scale and full-sized exploitation wells includes a reactor, configured to prepare a natural gas hydrate sample, for simulating an environment for forming a natural gas hydrate reservoir in seafloor sediments. The reactor includes a reactor body, an upper cover disposed at an upper surface of the reactor body, and a lower cover disposed at a lower surface of the reactor body; a gas introducing module, configured to introduce gas to the reactor during hydrate formation; a liquid introducing module, configured to introduce liquid to the reactor during hydrate formation; a temperature regulating module, configured to regulate a temperature in the reactor; a data collecting-processing-displaying module, configured to collect, store, process and display data of the comprehensive three-dimensional exploitation experimental system during an experiment.

Abstract: A method for controlling vibration of flexible mechanical arms based on cooperative tracking is disclosed, including: building a dynamic model of the flexible mechanical arm, according to a dynamic characteristic, constructing a flexible mechanical arm group made up of a plurality of flexible mechanical arms, assigning one of the plurality of flexible mechanical arms as a leader and the rest ones as followers which are required to track the leader's motion trajectory so as to realize cooperative work; designing cooperative control-based boundary controllers in combination with a Lyapunov method to realize cooperative work and suppress vibration of the flexible mechanical arms; and constructing a Lyapunov function using Lyapunov direct method to validate stability of the flexible mechanical arms under the control.

Abstract: The disclosure provides for systems, methods, and compositions for targeting polynucleotides. More particularly, the disclosure provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA and wherein the CRISPR effector protein is a Cas protein.

Abstract: A building envelope for a building wall, floor, or roof of a building, includes at least two shells spaced some distance apart from one another, which encloses an intermediate space therebetween, the shells including an exterior-facing shell configured to face an exterior of the building, and an interior-facing shell configured to face an interior of the building. The shells spaced apart from one another are filled with a building material and optionally include structural reinforcement and supply-engineering elements.

Abstract: A cooling system for cooling a machine tool having a machine temperature. The cooling system comprises gas source, refrigeration circulation, fan, and controller. The gas source is configured for providing gas. The refrigeration circulation comprises heat exchanger, compressor, condenser, and expansion valve. The heat exchanger is in fluid communication with the gas source and configured to cool the gas down to target temperature and to provide the gas to the machine tool. The compressor has operation frequency. The fan is configured to cool the condenser and has a rotation speed. The controller is connected to the compressor and the fan. When a target temperature difference that is equal to the machine temperature minus the target temperature is smaller than threshold temperature difference, the controller keeps the operation frequency at minimum frequency and sets the rotation speed to be smaller than a maximum rotation speed.

Abstract: A method and device for timing in time-varying distance protection based on multiple lines of a tower. The method includes: collecting an instantaneous current value at a time-varying distance protection installation location in the multiple lines of the tower, and acquiring preset parameters; calculating, according to the preset parameters and a multi-line ranging model, a multi-line ranging result; calculating, according to the preset parameters, the multi-line ranging result, and an adaptive calculation model, time of a section-II distance protection action and final time of a section-III distance protection action; and determining, according to the instantaneous current value, the preset parameters, and a cross-line failure auxiliary criterion model, final time of the section-II distance protection action.