Patents Assigned to INSTITUTE
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Patent number: 7249881Abstract: A method and apparatus for performing characterization of devices is presented. The characteristic of the device are determined by obtaining a first temperature measurement in a first location of a device, obtaining a second temperature measurement, computing the difference between the temperature measurements and, using the temperatures and/or the temperature difference, a characteristic of the device is determined.Type: GrantFiled: April 29, 2005Date of Patent: July 31, 2007Assignee: Massachusetts Institute of TechnologyInventors: Kevin P. Pipe, Rajeev J. Ram
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Patent number: 7251589Abstract: Computer-implemented systems and methods for performing forecast scoring based upon time series data that is indicative of a data generation activity occurring over a period of time. One or more data stores store historical data and future data. The historical data includes historical exogenous inputs. The future data includes future exogenous inputs. A dynamic statistical model receives the historical data and future data that are stored in the one or more data stores. The dynamic statistical model is to provide forecast scoring based upon the historical exogenous inputs and the future exogenous inputs. An optimizer having an objective function iteratively varies the future data, so that forecasts associated with the varying future data values are generated by the dynamic statistical model for evaluation by the objective function.Type: GrantFiled: May 9, 2006Date of Patent: July 31, 2007Assignee: SAS Institute Inc.Inventors: Keith E. Crowe, Rajesh S. Selukar, Michael J. Leonard
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Patent number: 7250134Abstract: A steel powder metal skeleton is infiltrated with an infiltrant composition similar to the skeleton, with an additional agent that depresses the melting point of the infiltrant relative to the skeleton. Infiltration is driven primarily by capillary pressure. The powder and infiltrant compositions differ primarily only in a higher concentration of a melting point depressant agent “MPD” in the infiltrant. Carbon (C) and silicon (Si) and several other elements can be elements in an MPD, either alone or in combination. Certain steel target compositions are such that a complementary infiltrant, and skeleton can be chosen such that a skeleton will remain solid at an infiltration temperature at which the infiltrant can be melted and fully infiltrated, and further where there is a persistent two phase field, with a liquid phase that is large enough (greater than 7% vol, and typically between 20 and 40 vol %) so that flow can be maintained without choke off from diffusional solidification.Type: GrantFiled: November 26, 2003Date of Patent: July 31, 2007Assignee: Massachusetts Institute of TechnologyInventors: Brian D. Kernan, Emanuel M. Sachs, Samuel M. Allen, Adam M. Lorenz
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Publication number: 20070172600Abstract: External energy is fed to N-[3-{3,5-bis{3,5-bis[3,5-bis(4-mercaptobenzylthio)benzylthio]benzylthio}benzyloxy}-propionyl-4-nitro-1-naphthylamine (18a) being a molecule capable of photosensitization as an intermediate excitation medium, fixed on support (12) of a metal, so as to photosensitized molecule of excited triplet state (18b), thereby inducing an excited triplet energy transfer from this photosensitized molecule to first molecule (28a) having a residue capable of bonding. The first molecule (28b) having thus been excited by the excited triplet energy transfer is bonded with second molecule (30) having a residue capable of bonding which is a bonding object to be bonded with the first molecule.Type: ApplicationFiled: April 23, 2004Publication date: July 26, 2007Applicant: National Institute of Information and Communication Technology IncorporatedInventors: Akiro Otomo, Seiichi Furumi, Hitoshi Suzuki, Hideki Miki, Shinro Mashiko
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Publication number: 20070171334Abstract: This invention provides a wide viewing angle liquid crystal display and a method for achieving wide viewing angle effect. The invention adds conductive nanoparticles in a liquid crystal layer of the present liquid crystal display. When a driving voltage is applied on the present liquid crystal display, an electric field applied on the liquid crystal layer is distorted by the conductive nanoparticles dispersed in the liquid crystal layer. A non-uniform electric field is hence formed in the liquid crystal layer and the liquid crystal molecules are prone to multi-directional alignments. As such, a wide viewing angle effect can be achieved.Type: ApplicationFiled: April 14, 2006Publication date: July 26, 2007Applicant: Industrial Technology Research InstituteInventors: Shie-Chang Jeng, Wei-Ting Hsu, Chi-Chang Liao
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Publication number: 20070174009Abstract: The present invention provides a method and system for analyzing a network of biological functions, such as transcriptional factors, structural genes, cellular markers, cell surface markers, cell shapes, organelle shapes, cell mobility, enzyme activities, metabolite concentrations, and localization of cellular components, in a biological entity such as a cell. Particularly, an object of the present invention is to provide a system and method for presenting biological information in a global manner without modification where the cell is considered a complex system.Type: ApplicationFiled: October 28, 2005Publication date: July 26, 2007Applicant: National Institute Of Advanced Industrial Science And TechnologyInventors: Masato Miyake, Tomohiro Yoshikawa, Takanori Ueda, Jun Miyake
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Publication number: 20070173643Abstract: The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of producing an N-alkyl product. Ammonia content of a solution is adjusted to produce a ratio of ammonia to di-carboxylate compound of from about 1:1 to about 1.5:1. An alkylating agent is added and the initial compound is alkylated and cyclized. The invention includes methods of making N-methyl pyrrolidinone (NMP). Aqueous ammonia and succinate is introduced into a vessel and ammonia is adjusted to provide a ratio of ammonia to succinate of less than 2:1. A methylating agent is reacted with succinate at a temperature of from greater than 100° C. to about 400° C. to produce N-methyl succinimide which is purified and hydrogenated to form NMP.Type: ApplicationFiled: March 19, 2007Publication date: July 26, 2007Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Todd Werpy, John Frye, James White, Johnathan Holladay, Alan Zacher
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Publication number: 20070171703Abstract: A current source for magnetic random access memory (MRAM) is provided, including a band-gap reference circuit, a first stage buffer, and a plurality of second stage buffers. The band-gap reference circuit provides an output reference voltage which is locked by the first stage buffer. The plurality of second stage buffers generate a stable voltage in response to the locked voltage, so as to provide a current for the conducting wire after being converted, such that magnetic memory cell changes its memory state in response to the current. The current source may reduce the discharge time under the operation of biphase current, so as to raise the operating speed. Further, the circuit area of the current source for the MRAM is also reduced. The operation of multiple write wires may be provided simultaneously to achieve parallel write.Type: ApplicationFiled: November 9, 2006Publication date: July 26, 2007Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Rei-Fu Huang, Young-Shying Chen, Chien-Chung Hung, Yuan-Jen Lee, Ming-Jer Kao
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Publication number: 20070173400Abstract: A supported catalyst system comprising the product obtainable by contacting an adduct of formula (I) MgT2a.yAlQj(OU)3-j??(I) wherein T is chlorine, bromine, or iodine; U is a linear or branched C1-C10 alkyl radical, y ranges from 6.00 to 0.05; j ranges from 3 to 0.1; Q substituents, are hydrocarbon radicals containing from 1 to 20 carbon atoms; with at least one compound selected from the compounds of formula (II), (III) and (IV) wherein M1 is a transition metal atom selected from Groups 3-11 of Periodical Table; each R1, R2, R3, R4, R5 and R8 is a hydrogen atom, a halogen atom or a hydrocarbon group; L and L1 are divalent or trivalent hydrocarbon groups; T1 is a Lewis base; A1 and A2 are oxygen sulfur or nitrogen containing groups and X is hydrogen halogen or hydrocarbon group.Type: ApplicationFiled: February 14, 2005Publication date: July 26, 2007Applicant: Stichting Dutch Polymer InstituteInventors: John Severn, John Chadwick
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Publication number: 20070170176Abstract: The present invention provides a composite tool bar which has a composite body part (10) covered with a covering (20), with a plurality of bites (TO1-T05) mounted on the composite body part (10) along a longitudinal direction. The composite tool bar includes a first insert (240) which is inserted into the composite body part (10). A bite mounting hole (210) is provided in the first insert (240) to receive a bite therein. A bite height adjusting hole (220) is axially aligned with the bite mounting hole (210) to receive therein a bite height adjusting bolt (BO1-B05). The composite tool bar further includes a second insert (250) which is inserted into the composite body part (10) to be coupled to the first insert (240). A bite holding hole (230) is provided in the second insert (250) to receive therein a bite holding bolt (B06-B10).Type: ApplicationFiled: September 22, 2004Publication date: July 26, 2007Applicant: Korea Advanced Institute of Science and TechnologyInventors: Dai Lee, Hui Hwang, Seung Lee, Byung Kim
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Publication number: 20070173438Abstract: [?[CH2NH]PG4] glycopeptide antibiotic analogs are reengineered forms of glycopeptides that exhibit antimicrobial activity against both wild type and glycopeptide antibiotic resistant strains of microorganisms. For example, [?[CH2NH]Tpg4] vancomycin aglycon is a reengineered form of vancomycin that exhibits antimicrobial activity (MIC=31 ?g/mL) against both wild type and VanA resistant organism (E. faecalis BM4166). The VanA resistant organism achieves its resistance, upon glycopeptide antibiotic challenge, by remodeling its D-Ala-D-Ala peptidoglycan cell wall precursor to D-Ala-D-Lac. [?[CH2NH]PG4] glycopeptide antibiotic analogs have an altered glycopeptide backbone wherein the carbonyl of the fourth amino acid residue of the glycopeptide backbone has been replaced with a methylene. This alteration of the glycopeptide backbone imparts dual binding affinities for both D-Ala-D-Ala and D-Ala-D-Lac and dual antimicrobial activities for both wild type and resistant strains.Type: ApplicationFiled: January 16, 2007Publication date: July 26, 2007Applicant: The Scripps Research InstituteInventor: Dale Boger
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Publication number: 20070169686Abstract: High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.Type: ApplicationFiled: March 21, 2007Publication date: July 26, 2007Applicants: California Institute of Technology, The Regents of the University of CaliforniaInventors: Stephen Quake, Carl Hansen, James Berger
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Publication number: 20070174221Abstract: A system and method for combining the model-based and genetics-based methods are combined according to a convergence criterion. When the population is not converged, the genetics-based approach is used, and when the population is converged, the model-based method is used to generate offspring. The algorithm benefits from using a model-based offspring generation only when the population shows a certain degree of regularity, i.e., converged in a stochastic sense. In addition, a more sophisticated method to construct the stochastic part of the model can be used. Also a biased Gaussian noise (the mean of the noise is not zero), as well as a white Gaussian noise (the mean of the noise is zero) can be preferably used for the stochastic part of the model.Type: ApplicationFiled: January 16, 2007Publication date: July 26, 2007Applicant: HONDA RESEARCH INSTITUTE EUROPE GMBHInventors: Bernhard Sendhoff, Yaochu Jin, Edward Tsang, Qingfu Zhang, Aimin Zhou
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Publication number: 20070171015Abstract: The magnetic field in an acceleration chamber defined by a magnet structure is shaped by shaping the poles of a magnetic yoke and/or by providing additional magnetic coils to produce a magnetic field in the median acceleration plane that decreases with increasing radial distance from a central axis. The magnet structure is thereby rendered suitable for the acceleration of charged particles in a synchrocyclotron. The magnetic field in the median acceleration plane is “coil-dominated,” meaning that a strong majority of the magnetic field in the median acceleration plane is directly generated by a pair of primary magnetic coils (e.g., superconducting coils) positioned about the acceleration chamber, and the magnet structure is structured to provide both weak focusing and phase stability in the acceleration chamber. The magnet structure can be very compact and can produce particularly high magnetic fields.Type: ApplicationFiled: January 19, 2007Publication date: July 26, 2007Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Timothy Antaya
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Publication number: 20070174923Abstract: The present invention discloses nucleic acids, proteins, and antibodies for SALL4 (including isoforms SALL4A, SALL4B, and SALL4C), a zinc finger transcriptional factor. Further, methods are disclosed which demonstrate that constitutive expression of SALL4 increases leukemogenic potential in cells of model animal systems. Moreover, constitutive expression of select isoforms (e.g., SALL4B) in transgenic mice demonstrate that these animals develop myelodysplastic syndrome (MDS)-like signs and symptoms, including subsequent acute myeloid leukemia (AML), which is transplantable. The disclosure also provides methods for identifying and purifying embryonic stem cells, adult stem cells, cancer stem cells, including leukemia stem cells, methods for identifying substances which bind to and/or modulate SALL4, methods for diagnosing MDS in a subject, and methods of treating a subject presenting MDS.Type: ApplicationFiled: November 29, 2006Publication date: July 26, 2007Applicant: Nevada Cancer InstituteInventor: Yupo Ma
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Publication number: 20070174377Abstract: The present invention provides a system for analyzing a time series signal by a method of Chaos Theory and calculating a chaos theoretical exponent value.Type: ApplicationFiled: July 21, 2006Publication date: July 26, 2007Applicants: ELECTRONIC NAVIGATION RESEARCH INSTITUTE, AN INDEPENDENT ADMINISTRATIVE INSTITUTION (25%)Inventors: Kakuichi SHIOMI, Susumu KOBAYASHI
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Publication number: 20070172402Abstract: A compact integrated combustion reactor is described. In a preferred embodiment, the combustion catalyst is disposed in a staggered configuration such that the hot spot in an adjacent endothermic reaction chamber is substantially less than would occur with a conventional, unstaggered configuration. The integrated reactor may also include a methanation chamber for methanation of a reformate product. Systems containing reactant and product streams, and methods of conducting integrated combustion reactions are also described. A staggered catalyst conformation can be used more broadly for thermal chemical reactions requiring heat transfer in a layered device.Type: ApplicationFiled: December 15, 2006Publication date: July 26, 2007Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Daniel Palo, Jamelyn Holladay, Robert Dagle, Robert Rozmiarek
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Publication number: 20070171351Abstract: To obtain truly flexible electro-optic films for image display or other related applications and to obtain a low cost solution for making electro-optic films, a new concept for manufacturing such films is disclosed. The method disclosed in this invention include mixing liquid crystal with “sponge particles” having fibril or porous surface morphology, coating such mixture directly on substrates with conductive electrodes and laminating with release liner or another substrate having conductive electrodes. The electro-optic films manufactured by using traditional R2R coating techniques. The electro-optic film manufactured by the method disclosed in the invention can be used for segment type, passive matrix type or active matrix type display applications or other related applications.Type: ApplicationFiled: July 28, 2006Publication date: July 26, 2007Applicant: Industrial Technology Research InstituteInventors: Wei-Hsin Hou, Hsing-Lung Wang, Chi-Chang Liao, Kang-Hung Liu, Shie-Chang Jeng
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Publication number: 20070171526Abstract: Methods and systems for determining position relative to a stereographic pattern generator including capturing an image of a stereographic pattern from a known stereographic pattern generator with a viewer. The location of portion of the stereographic pattern is determined relative to the stereographic pattern generator is then determined with a processor. The location information is used to find the orientation of the viewer relative to the pattern generator.Type: ApplicationFiled: January 26, 2006Publication date: July 26, 2007Applicant: MASS INSTITUTE OF TECHNOLOGY (MIT)Inventor: Eric Feron
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Publication number: 20070172801Abstract: Devices for training in extinguishing fires comprising a control unit and a flame generation unit as well as methods and systems of use thereof are presented.Type: ApplicationFiled: February 7, 2007Publication date: July 26, 2007Applicant: RENSSELAER POLYTECHNIC INSTITUTEInventors: Paul R. Darois, Steven Galonska, Burt L. Swersey, John Blackburn, Travis B. Bashaw