Patents Assigned to INSTITUTE
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Patent number: 7247719Abstract: Oligonucleotide primers and polynucleotide probes provide selective amplification and detection of Id genetic sequences and are selected both (1) to provide the desired specificity so that they amplify only the specific Id type to which they are targeted; and (2) to introduce terminal restriction endonuclease cleavage sites into the amplicon that facilitate the incorporation of the amplicon into plasmid-based vectors. Detection of Id genetic sequences can be carried out using the labeled-amplicon by reamplifying the amplicon with the primers in the presence of labeled, for example radiolabeled, deoxynucleotide triphosphates. The probes of the invention correspond in sequence to the amplicons produced using the primers of the invention, after cleavage at the restriction endonuclease sites.Type: GrantFiled: June 3, 2004Date of Patent: July 24, 2007Assignee: Sloan-Kettering Institute for Cancer ResearchInventor: Robert Benezra
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Patent number: 7248616Abstract: There are provided a bi-directional transceiver module and a method for driving the same. The bi-directional transceiver module includes a 1.3 ?m Distributed Bragg Reflection Laser Diode (DBR LD) including an active layer which performs light-emission in response to a light at 1.3 ?m and a DBR mirror formed near the active layer. The DBR mirror is formed to prevent an upstream signal emerging from the 1.3 ?m DBR LD from being deleted by a PD. A monitoring PD and a PD for detecting an optical signal are integrated and mounted behind the DBR mirror using a butt-joint method. The 1.3 ?m DBR LD, the monitoring PD, and the PD for detecting the optical signal are electrically isolated by insulated areas. To drive the bi-directional transceiver module, a forward bias (+) is applied to a p-electrode formed on the 1.3 ?m DBR LD, a backward bias (?) is applied to p-electrodes formed on the monitoring PD and the PD for detecting the optical signal, and a n-electrode as a common electrode is grounded.Type: GrantFiled: November 14, 2003Date of Patent: July 24, 2007Assignee: Electronics and Telecommunications Research InstituteInventors: Sung Bock Kim, Eundeok Sim, Ki Soo Kim
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Patent number: 7248654Abstract: An apparatus and a method for controlling a gain of I-channel signal and compensating Q-channel signal in response to the gain imbalance based on the gain-controlled I-channel signal as a reference channel signal is disclosed. The apparatus includes: an auto gain controller for controlling a gain of a signal selected from the I-channel signal and the Q-channel signal to have a predetermined amplitude, thereby generating a gain-controlled signal; a detector for detecting a gain imbalance between the gain-controlled signal and the remaining channel signal; and a compensator for compensating the gain imbalance of the remaining channel signal based on the detected gain imbalance.Type: GrantFiled: May 27, 2004Date of Patent: July 24, 2007Assignee: Electronics and Telecommunications Research InstituteInventors: Yun-Jeong Song, Young-Wan Kim, Ho-Jin Lee
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Patent number: 7247731Abstract: One aspect of the present invention relates to novel ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.Type: GrantFiled: September 16, 2005Date of Patent: July 24, 2007Assignee: Massachusetts Institute of TechnologyInventors: Stephen L. Buchwald, David W. Old, John P. Wolfe, Michael Palucki, Ken Kamikawa
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Patent number: 7248610Abstract: A laser driver. The laser driver comprises a diode driver, a power detector, a first extreme detector, a second extreme detector and a current controller. The diode driver receives bias and modulation currents to control a laser diode for generating light signals. The power detector detects optical power of the light signals. The first and second extreme detectors, both coupled to the power detector, detect the first and second extreme values among detected optical power. The first extreme value is either the maximum or the minimum optical power of the light signals, while the second extreme value is the other.Type: GrantFiled: May 3, 2005Date of Patent: July 24, 2007Assignee: Industrial Technology Research InstituteInventors: Day-Uei Li, Li-Ren Huang, Wei-Zen Chen
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Publication number: 20070166232Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles comprise a core represented as FexMavZy and a shell of an inner-transition element Mb or the compound thereof, wherein Ma is an inner-transition element, Z is an element of the group Vla, x is greater or equal to 0, and v, y are positive numbers. The surface of the shell is optionally modified by liposome, polymer, aliphatic compound, aromatic compound or combinations thereof.Type: ApplicationFiled: March 19, 2007Publication date: July 19, 2007Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
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Publication number: 20070167638Abstract: Multiphasic reactions, especially those reactions using a phase transfer catalyst, are conducted in microchannel apparatus. Advantageously, these reactions can be conducted with two, planar microlayers of reactants in adjacent laminar flow streams. Microchannel apparatus and methods for conducting unit operations such as reactions and separations in microchannel apparatus is also described. Microchannel apparatus can provide advantages for controlling reactions and separating products, solvents or reactants in multiphase reactions.Type: ApplicationFiled: July 26, 2006Publication date: July 19, 2007Applicant: Battelle Memorial InstituteInventors: John Brophy, Bruce Monzyk
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Publication number: 20070167992Abstract: The present invention includes an apparatus, kit and method for providing neural stimulation to reduce preterm labor contractions and thereby reduce subsequent preterm births. The present invention includes one or more implantable electrodes adapted for electrical communication with one or more sacral nerve roots and an electrical energy generator to produce one or more electrical signals in electrical communication with the one or more implantable electrodes.Type: ApplicationFiled: January 18, 2006Publication date: July 19, 2007Applicant: Baylor Research InstituteInventor: Michael Carley
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Publication number: 20070166218Abstract: It is aimed at providing an oxynitride powder, which is suitable for usage as a phosphor, is free from coloration due to contamination of impurities, and mainly includes a fine ?-sialon powder. An oxynitride powder is produced by applying a heat treatment in a reducing and nitriding atmosphere, to a precursor compound including at least constituent elements M, Si, Al, and O (where M is one element or mixed two or more elements selected from Li, Mg, Ca, Sr, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu), thereby decreasing an oxygen content and increasing a nitrogen content of the precursor.Type: ApplicationFiled: April 22, 2005Publication date: July 19, 2007Applicant: National Institute For Materials ScienceInventors: Naoto Hirosaki, Takayuki Suehiro
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Publication number: 20070166331Abstract: A novel prophylactic/remedy for immunopathy is provided which is not neutralized by a neutralizing antibody to Staphylococcal enterotoxin B (SEB), known as one of superantigens, and may effectively act as a superantigen. A modified SEB having a reduced reactivity with a neutralizing antibody to SEB (anti-SEB antibody) and a prophylactic/remedy for immunopathy comprising as an active ingredient said modified SEB. The modified SEB of the present invention may be prepared with the evolutionary molecular engineering technique by introducing amino acid substitution in the amino acid sequence of SEB, especially at an epitope recognition site of the anti-SEB antibody in the amino acid sequence of SEB.Type: ApplicationFiled: March 28, 2003Publication date: July 19, 2007Applicants: Juridical Foundation The Chem-Sero-Therapeutic Research Institute, Kowa Company Ltd.Inventors: Toshihiro Nakashima, Takumi Sasaki, Kazuhiko Kimachi, Shigeki Kuwata, Tsukasa Nishihara, Atsuko Sakata, Masao Ohkuchi, Tomoyuki Koshi, Toshiyuki Edano
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Publication number: 20070166917Abstract: A non-volatile memory device and fabricating method therefor are provided. The non-volatile memory device includes a substrate, a first insulating layer, a conductor layer, a second insulating layer, and charge storage units. Herein, the substrate, the first insulating layer, and the conductor layer are formed, respectively. Then, the second insulating layer is disposed on the sidewalls of the first insulating layer and the conductor layer, and multiple charge storage units are formed within the second insulating film. As such, the charge storage units separated from one another effectively to improve the phenomenon of crosstalk, and provide multi-bit storage capability. Furthermore, a multi-layer charge storage structure perpendicular to and parallel to the substrate is used to enlarge the charge storage capacity.Type: ApplicationFiled: September 12, 2006Publication date: July 19, 2007Applicant: Industrial Technology Research InstituteInventors: Pei-Je Tzeng, Cha-Hsin Lin, Lurng-Shehng Lee
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Publication number: 20070168148Abstract: A test method of an embedded capacitor and test system thereof are provided. The method and system are used to determine an electrical specification of the embedded capacitive component in a circuit board substrate, thereby avoiding executing a follow-up fabricating process for the circuit board substrate not satisfying the desired specification. In the method and system, a geometric size of the embedded capacitor is measured, and a relation value between the electrical parameter and the geometric size and a standard electrical parameter are obtained from a model database, to calculate the electrical parameter of the embedded capacitor. Then, the electrical parameter of the embedded capacitor is compared with the standard electrical parameter, to obtain an error value. Therefore, according to the error value, it may be acquired whether or not the circuit board substrate satisfies set electrical specifications.Type: ApplicationFiled: November 1, 2006Publication date: July 19, 2007Applicant: Industrial Technology Research InstituteInventors: Uei-Ming Jow, Chin-Sun Shyu, Chang-Sheng Chen, Min-Lin Lee, Shinn-Juh Lai
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Publication number: 20070168012Abstract: Methods of making coated implantable medical devices are provided. The methods include positioning a first layer comprising a bioactive on at least a portion of a structure, and positioning at least one porous layer over the first layer. The at least one porous layer has a thickness adequate to provide a controlled release of the bioactive.Type: ApplicationFiled: November 27, 2006Publication date: July 19, 2007Applicants: MED Institute, Inc., Cook IncorporatedInventors: Anthony Ragheb, Brian Bates, Neal Fearnot, Thomas Kozma, William Voorhees
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Publication number: 20070167195Abstract: A communication system, a method for extending stand-by time, and a computer readable medium therefor are provided. The communication system includes a mobile communication apparatus and a core network. The method and the computer readable medium therefor perform the following steps. When the mobile communication apparatus is in a low battery situation or required to enter a power saving mode by a user, it sends a signal to the core network to request to enter the power saving mode. After receiving the signal, the core network reduces a data quantity transmitted to the mobile communication apparatus, and thereby the purpose of extending stand-by time is achieved.Type: ApplicationFiled: May 19, 2006Publication date: July 19, 2007Applicant: INSTITUTE FOR INFORMATION INDUSTRYInventors: Chih-Wei Su, Xiang-Rui Chung, Kun-Hung Lee
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Publication number: 20070164396Abstract: A multi-functional composite substrate structure is provided. The first substrate with high dielectric constant and the second substrate with low dielectric constant and low loss tangent are interlaced above the third substrate. One or more permeance blocks may be formed above each substrate, so that one or more inductors may be fabricated thereon. One or more capacitors may be fabricated on the first substrate. Also, one or more signal transmission traces of the system impedance are formed on the second substrate of the outside layer. Therefore, the inductance of the inductor(s) is effectively enhanced. Moreover, the area of built-in components is reduced. Furthermore, it has shorter delay time, smaller dielectric loss, and better return loss for the transmission of high speed and high frequency signal.Type: ApplicationFiled: December 28, 2006Publication date: July 19, 2007Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Uei-Ming Jow, Chang-Sheng Chen, Chin-Sun Shyu, Min-Lin Lee, Shinn-Juh Lay, Ying-Jiunn Lai
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Publication number: 20070166791Abstract: This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.Type: ApplicationFiled: February 22, 2007Publication date: July 19, 2007Applicant: The Scripps Research InstituteInventors: Jason Chin, T. Cropp, J. Anderson, Peter Schultz
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Publication number: 20070164656Abstract: An apparatus for generating a planar light source and method for driving the same is provided. The apparatus for generating a planar light source comprises an emitting layer disposed not only on a cathode electrode, but also on a gate electrode as well. Accordingly, by applying an AC voltage to the apparatus, a duty cycle of the AC voltage can reach 100% so as to enhance the brightness to the extent that the apparatus is applied a DC voltage.Type: ApplicationFiled: June 28, 2006Publication date: July 19, 2007Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Wei-Yi Lin, Biing-Nan Lin, Ming-Chun Hsiao, Liang-You Jiang
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Publication number: 20070166203Abstract: The present invention provides a self-sealing high-temperature biochemical reaction apparatus and a method for the same. The present apparatus has a microfluidic channel including a main channel chamber, an inlet sub-channel and an outlet sub-channel. The main channel chamber has an inlet and an outlet respectively communicated with the inlet sub-channel and outlet sub-channel. The inner diameters of the inlet sub-channel and outlet sub-channel are smaller than that of the main channel chamber. The present invention controls the temperature gradient of the main channel chamber and sub-channels during the biochemical reaction such that the microfluid itself becomes self-sealing material to seal the openings of the sub-channels during the high-temperature reaction. The microfluid would not be vaporized to adversely influence the reaction result.Type: ApplicationFiled: May 1, 2006Publication date: July 19, 2007Applicant: Industrial Technology Research InstituteInventors: Chien-Chih Huang, Mei-Ya Wang
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Publication number: 20070169130Abstract: An apparatus of dynamic anti-vibration for a storage device to support a storage device in a housing is provided. The apparatus includes a base board for holding the storage device, a plurality of damping elements coupled to the base board and the housing which have damping characteristics to dissipate kinetic energy and reduce the vibration of the base board, and at least one actuator coupled to the base board and the housing which generates a force to neutralize the vibration of the base board.Type: ApplicationFiled: June 7, 2006Publication date: July 19, 2007Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventor: Min-Der WU
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Publication number: 20070164308Abstract: A light emitting apparatus has a light emitting element with an emission wavelength in the range of 360 to 550 nm and a rare-earth element doped oxide nitride phosphor or cerium ion doped lanthanum silicon nitride phosphor. Part of light radiated from the light emitting element is wavelength-converted by the phosphor. The light emitting apparatus radiates white light generated by a mixture of the wavelength-converted light and the other part of light radiated from the light emitting element.Type: ApplicationFiled: March 13, 2007Publication date: July 19, 2007Applicants: TOYODA GOSEI CO., LTD., INDEPENDENT ADMINISTRATIVE INSTITUTION, NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Naoki Yoshimura, Yoshinobu Suehiro, Yuji Takahashi, Koichi Ota, Mamoru Mitomo, Tadashi Endo, Masakazu Komatsu