Patents Assigned to INSTITUTE
  • Patent number: 7239775
    Abstract: An optical delay line for use with an optical source including input/output optics optically coupled to the optical source and a curved mirror with a reflective surface that is centered about an evolute curve of the delay line to retro-reflect light traveling along a delay line beam path tangent to the edge of the evolute curve. The input/output optics direct light from the optical source along the delay line beam path and direct delayed light from the delay line beam path out of the optical delay line along an output beam path. The input/output optics and/or the curved mirror rotate about the evolute curve at a selected angular speed. The reflective surface has a curvature based on a parametric curve that is calculated from the evolute curve such that the delay of the delay line varies according to a predetermined function as the input/output optics and/or the curved mirror rotate.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: July 3, 2007
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Jingzhou Xu, Xi-Cheng Zhang
  • Patent number: 7239903
    Abstract: In addition to irradiating examination light toward the inside of the bead of the subject and detecting the examination light reflected from the head: structural data indicating the head structure, wherein the head is divided into multiple materials and the various materials are further divided into multiple elements, are stored in a structural data storage unit set up in a specified region of memory; the optical properties of the aforementioned elements are calculated from a given specified initial value; the hemodynamics inside the brain of the subject are calculated based on the optical properties thereof, and the aforementioned initial values are taken to be the optical properties when the light intensity signal values, provisionally calculated from optical properties under the assumption that the optical properties are uniform for each of the aforementioned materials, are in a fixed range of the actually measured light intensity signal values.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: July 3, 2007
    Assignee: National Institute of Information and Communications Technology
    Inventor: Hideo Eda
  • Patent number: 7238412
    Abstract: An optical device is provided. The optical device includes a plurality of high index layers. The optical device also includes a plurality of low index layers. The optical device is formed by creating alternating layers of the plurality of high layers and the plurality of low index layers, such that electricity and heat is allowed to be conducted through said optical device.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: July 3, 2007
    Assignee: Massachusetts Institute of Technology
    Inventors: Desmond R. Lim, Kazumi Wada, Lionel C. Kimerling
  • Patent number: 7238276
    Abstract: The present invention relates to a medium-pressure hydrocracking process which uses a fresh hydrogen resource and a hydrosaturation catalyst with reduced metals of group VIB and/or group VIII as the active ingredients to selectively and deeply hydrosaturate jet fuel and/or diesel cuts derived in the medium-pressure hydrocracking process.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: July 3, 2007
    Assignees: China Petroleum Corporation, Fushun Research Institute of Petroleum and Petrochemicals
    Inventors: Xiangchen Fang, Ling Lan, Xiaobing Song, Minghua Guan, Guang'an Jiang, Fenglai Wang, Zhengnan Yu, Qun Guo
  • Patent number: 7238715
    Abstract: A method of treating a patient suffering from pancreatitis comprising treating said patient with a therapeutically effective amount of a cholinergic agonist selective for an ?7 nicotinic receptor in an amount sufficient to decrease the amount of the proinflammatory cytokine that is released from a macrophage wherein said condition is acute pancreatitis. The compounds of the present invention include a quaternary analog of cocaine; (1-aza-bicyclo[2.2.2]oct-3-yl)-carbamic acid 1-(2-fluorophenyl)-ethyl ester; a compound of formula (I), a compound of formula (II), a compound of formula (III), a compound of formula (IV), and an oligonucleotide or mimetic capable of attenuating the symptoms of acute pancreatitis wherein the oligonucleotide or mimetic consists essentially of a sequence greater than 5 nucleotides long that is complementary to an mRNA of an ?7 cholinergic receptor.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: July 3, 2007
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Kevin J. Tracey, Hong Wang
  • Patent number: 7238797
    Abstract: The invention provides a transgenic pig having incorporated into its genome a HSP70 gene or fragment thereof, whereby the transgenic pig overexpresses HSP70. The transgenic pig of the invention can be used in the production of HSP in large quantities, as a xenograft source for transplation and as an animal model close to human for illustrating the protective roles of HSP. Furthermore, the transgenic pig of the invention has a better meat quality and exhibits an increased growth rate and a reduced backfat thickness.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: July 3, 2007
    Assignee: Animal Technology Institute
    Inventors: Wen-Chuan Lee, Ming-Yu Chen
  • Patent number: 7238864
    Abstract: The present invention provides methods for inducing tissue-specific expression, which includes preparing an expression vector having a promoter. The promoter includes any one of the following DNAs (a) to (c): (a) a DNA, which includes the nucleotide sequence shown in SEQ ID NO: 1; (b) a DNA, which includes the nucleotide sequence ranging from nucleotides 1344 to 2843 of SEQ ID NO: 1; and (c) a DNA, which is a DNA fragment that can hybridize under stringent conditions to a DNA fragment including a nucleotide sequence fully complementary to the nucleotide sequence shown in SEQ ID NO: 1, wherein (a), (b) or (c) can control the transcription of a coding sequence located downstream thereof; and wherein the stringent conditions are 5×SSC at 42° C.; The expression vector, also, includes a coding sequence located downstream of the promoter.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: July 3, 2007
    Assignees: Kumiai Chemical Industry Co., Ltd., National Institute of Agrobiological Sciences
    Inventors: Seiichi Toki, Hiroaki Ichikawa, Hidemitsu Nakamura, Kiyoshi Kawai, Koichiro Kaku, Tsutomu Shimizu
  • Patent number: 7239986
    Abstract: Methods and apparatus for classifying or predicting the classes for samples based on gene expression are described. Also described are methods and apparatus for ascertaining or discovering new, previously unknown classes based on gene expression.
    Type: Grant
    Filed: February 12, 2002
    Date of Patent: July 3, 2007
    Assignees: Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Inc.
    Inventors: Todd R. Golub, Eric S. Lander, Jill Mesirov, Donna Slonim, Pablo Tamayo
  • Patent number: 7238682
    Abstract: Bifunctional molecules comprising two hsp-binding moieties which bind to hsp90 in the pocket to which ansamycin antibiotics bind connected via a linker are effective for inducing the degradation and/or inhibition of HER-family tyrosine kinases. For example, a compound of two geldanamycin moities joined by a four-carbon linker provides selective degradation of HER-family tyrosine kinases, without substantially affecting other kinases. These compounds can be used for treatment of HER-positive cancers with reduced toxicity, since these compounds potently kill cancer cells but affect fewer proteins than geldanamycin.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: July 3, 2007
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Neal Rosen, Scott D. Kuduk, Samuel J. Danishefsky, Furzhong F. Zheng, Laura Sepp-Lorenzino, Ouatek Ouerfelli
  • Patent number: 7239954
    Abstract: A method for rapidly transitioning from a lean combustion mode to a rich combustion mode, such as often required for the regeneration of aftertreatment devices, is provided by abrupt intake air reduction and a concurrent abrupt increase in fuel injection quantity with accompanying retardation of fuel injection timing. The abrupt increase in fuel quantity is to a maximum value sufficient to immediately provide a defined initial rich air/fuel ratio for a coexistent oxygen concentration in the cylinder. The fuel quantity is then proportionally reduced from the maximum value to a target fuel quantity to maintain a target air/fuel ratio during the transition. Simultaneously, injection timing is abruptly retarded to a value sufficient to avoid torque increase as a result of the increased injected fuel. The injection timing is subsequently proportionally advanced from the abruptly retarded timing value when the target fuel quantity and air/fuel ratio values are achieved.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: July 3, 2007
    Assignee: Southwest Research Institute
    Inventor: Yiqun Huang
  • Patent number: 7238420
    Abstract: A method for preparing an ?-Al2O3 nanotemplate of fully crystalline ?-Al2O3 directly on the surface of a metal alloy is provided. Also provided is a related apparatus.
    Type: Grant
    Filed: June 17, 2004
    Date of Patent: July 3, 2007
    Assignee: Trustees of Stevens Institute of Technology
    Inventors: Woo Y. Lee, Yi-Feng Su, Limin He, Justin Daniel Meyer
  • Patent number: 7238265
    Abstract: The present invention provides a fountain-type electroplating apparatus with functions of voltage detection and flow rectification, comprising: an electroplating tank, a rectification device, and an overflow tank, wherein the electroplating tank is positioned inside the overflow tank, and the rectification device is arranged under the electroplating tank, in addition, the electroplating tank is composed of a shell, a cathode electrode, and an mesh shaped anode. The apparatus of the present invention further comprises: a power supplier, a switcher, a plurality of detection circuits, and a plurality of connecting line, which is used for monitoring the same.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: July 3, 2007
    Assignee: Industrial Technology Research Institute
    Inventors: Chih-Cheng Wang, Chih-Yuan Tseng, Jen-Rong Huang, Sheng-Lang Lee, Chia-Ming Chen, Pang-Ming Chiang
  • Patent number: 7239759
    Abstract: Disclosed is a spatial image information method and system for rapid and efficient storage in a relation type database and retrieval and management of spatial images acquired by a combined system of a global positioning system (GPS), an inertial navigation system (INS), and an image acquisition device (i.e., CCD camera). The spatial image acquired by the GPS/INS/CCD camera combined system is combined with an exterior orientation composed of a camera position (x,y,z), accelerated velocity, slope and direction at the moment the image is acquired and an interior orientation acquired by a camera calibration, so that calculation of a specified spatial coordinate information becomes possible.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: July 3, 2007
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Kwang Woo Nam, Jong Hun Lee, Jae Jun Yoo, In Hak Joo, Min Soo Kim
  • Patent number: 7240282
    Abstract: A system including a site specifying portion for receiving an identifier of a base site that becomes the basis of a displayed presentation and receives an identifier of a compared site displayed in a language different from that of the base site, a base page specifying portion that specifies a base page from the base site, a language converting portion that consolidates words of different languages into a single language, an aggregated word information producing portion that produces information for comparing the base page, a related page specifying portion that specifies a related page similar to the base page from among each compared page based on the word information of the base page and the word information of each compared page, and a display controlling portion that presents the related page together with the base page on the same display screen.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: July 3, 2007
    Assignee: National Institute of Information and Communications Technology
    Inventors: Akiyo Nadamoto, Katsumi Tanaka
  • Patent number: 7239846
    Abstract: The present invention relates to a signal modulation loop for the multi-mode mobile communication. The adaptive up-conversion modulation loop is applied in the multi-mode mobile communication, and is used for signal integration for the communication system comprising the second generation communication system, the global system for mobile communication (GSM), and the third generation communication system, the wideband code division multiple access (WCDMA), so as to achieve the object of multi-mode communication by using a single modulation loop.
    Type: Grant
    Filed: January 5, 2004
    Date of Patent: July 3, 2007
    Assignee: Industrial Technology Research Institute
    Inventors: Huan-Ke Chiu, June-Ming Hsu, Tzu-Yi Yang
  • Patent number: 7240239
    Abstract: The present invention provides an input and output device for computer system storage that can prevent a computer system being fatally damaged by a computer virus, and also provides a software execution method that by using the input and output device, enables trial software, trial data and mail data to be safely tried. For this, a virtual computer system is used that runs on a computer system. Writes to a hard disk in the virtual computer system are made via a disk cache, and whether or not data is transferred from the disk cache to the hard disk is controlled. Application program snapshot data created by the computer system is recorded on a recording medium that is substantially read-only or transmitted to a different computer system. The snapshot data from the recording medium is read or received by the different computer system and a processing by the application program is resumed in the state in which data transfer from the disk cache to the first storage has stopped.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: July 3, 2007
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventor: Kuniyasu Suzaki
  • Patent number: 7238941
    Abstract: A method (and resulting structure) for fabricating a sensing device. The method includes providing a substrate comprising a surface region and forming an insulating material overlying the surface region. The method also includes forming a film of carbon based material overlying the insulating material and treating to the film of carbon based material to pyrolyzed the carbon based material to cause formation of a film of substantially carbon based material having a resistivity ranging within a predetermined range. The method also provides at least a portion of the pyrolyzed carbon based material in a sensor application and uses the portion of the pyrolyzed carbon based material in the sensing application. In a specific embodiment, the sensing application is selected from chemical, humidity, piezoelectric, radiation, mechanical strain or temperature.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: July 3, 2007
    Assignee: California Institute of Technology
    Inventors: Yu-Chong Tai, Matthieu Liger, Scott Miserendino, Satoshi Konishi
  • Patent number: 7238775
    Abstract: Analogs of SRIF which are selective for SSTR4 in contrast to the other cloned SRIF receptors are useful in determining tissue and cellular expression of the receptor SSTR4 and its biological role in regulating tumor growth. SRIF analog peptides, such as des-AA1,2,4,5,12,13[Ala7]-SRIF; des-AA1,2,4,5,12,13[Aph7]-SRIF, des-AA1,2,4,5,12,13[Aph7]Cbm-SRIF; des-AA1,2,4,5,12,13[Tyr2,Ala7]-Cbm-SRIF, and des-AA1,2,4,5,12,13[Tyr7,C?Me-L-2Nal8]-SRIF, and counterparts incorporating D-Cys3 and/or D-Trp8 and/or Ala11, bind with high affinity to the cloned human receptor SSTR4 and activate the receptor, but they do not bind with significant affinity to human SSTR1, SSTR2, SSTR3 or SSTR5. By incorporating an iodinated tyrosine in position-2 in these SSTR4-selective SRIF analogs, a labeled compound useful in drug-screening methods is provided. Alternatively, for use in therapy, cytotoxins or highly radioactive elements can be N-terminally coupled or complexed thereto.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: July 3, 2007
    Assignee: The Salk Institute for Biological Studies
    Inventors: Jean E. F. Rivier, Jean Claude Reubi, Judit Erchegyi, Roland Riek
  • Publication number: 20070149770
    Abstract: Polynucleotides encoding chimeric proteins, and methods for their production and use are disclosed. The chimeric proteins comprise a flexible linker between two zinc finger DNA-binding domains, wherein the linker contains eight or more amino acids between the second conserved histidine residue of the carboxy-terminal zinc finger of the first domain and the first conserved cysteine residue of the amino-terminal zinc finger of the second domain.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 28, 2007
    Applicant: Massachusetts Institute of Technology
    Inventors: Jin-Soo Kim, Carl Pabo
  • Patent number: D545942
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: July 3, 2007
    Assignee: Battelle Memorial Institute
    Inventors: Robert E. Mora, R. Reade Harpham