Abstract: Compounds that inhibit COMT enzyme and pharmaceutical compositions comprising the same are provided herein. Methods of treating various psychiatric and neurological disorders with the compounds and pharmaceutical compositions described herein are also provided.

Abstract: Disclosed herein is an anode for a secondary battery manufactured thereby. The anode for a secondary battery includes a first adhesive member and a second adhesive member to which a plurality of electrolytes are fused, a first case configured to be fused to the first adhesive member, and a second case configured to be fused to the second adhesive member and the first case and into which an anode active material and a liquid electrolyte are injected. The anode has an effect of maximizing a reaction area because an electrolyte is exposed at both surfaces of the anode for a secondary battery.

Abstract: The present invention relates to compositions and methods for detecting CDK4/6 response and resistance.

Abstract: The invention discloses a monitoring system for deformations and destructions of a gas storage, including an acoustic emission sensor installed in a borehole of a monitored rock mass and a ground workstation. The acoustic emission sensor includes an acoustic emission probe and a probe installation mechanism for installing the acoustic emission probe and a transmission mechanism for transmitting the probe installation mechanism. The probe installation mechanism includes a shell, a probe sleeve and two sets of pistons hydro-cylinder components. The present invention realizes the control of the moving direction of the shell and the probe sleeve by the piston hydro-cylinder component and the hydraulic pump, thus solving the problem of effective installation and coupling of the acoustic emission probe, ensuring the effective coupling between the acoustic emission probe and the wall of the borehole.

Abstract: The invention provides an antisense oligonucleotide reduced in toxicity. The antisense oligonucleotide has a central region, a 5?-side region and a 3?-side region, wherein the central region has a nucleotide (2?-3? bridged nucleotide) in which the 2?-position and the 3?-position of a sugar moiety are bridged and/or a non-bridged nucleotide (3?-position-modified non-bridged nucleotide) having a substituent at the 3?-position.

Abstract: Provided is a humidity sensor including a support body, an RFID chip, an antenna, and a capacitor on the support body, a top cover sheet on the RFID chip and the antenna, and a hydrophobic material pattern on the capacitor, wherein the capacitor is exposed by the top cover sheet, the hydrophobic material pattern has a network shape including a plurality of holes, and an electrostatic capacitance of the capacitor changes according to humidity.

Abstract: A biosignal-based avatar control system according to an embodiment of the present disclosure includes an avatar generating unit that generates a user's avatar in a virtual reality environment, a biosignal measuring unit that measures the user's biosignal using a sensor, a command determining unit that determines the user's command based on the measured biosignal, an avatar control unit that controls the avatar to perform the command, an output unit that outputs an image of the avatar in real-time, and a protocol generating unit for generating a protocol that provides predetermined tasks, and determines if the avatar performed the predetermined tasks. According to an embodiment of the present disclosure, it is possible to provide feedback in real-time by understanding the user's intention through analysis of biosignals and controlling the user's avatar in a virtual reality environment, thereby improving the user's brain function and motor function.

Abstract: A method and system for measuring an inert gas by an ion probe. Embedding a to-be-measured sample into an epoxy resin, to obtain a sample target, where the to-be-measured sample includes an inert gas atom; after putting the obtained sample target into an analysis chamber of the ion probe, vacuumizing the analysis chamber, where the ion probe includes a primary ion source, an electron gun, a mass analyzer, and an ion detector; bombarding the sample target by using a primary ion beam formed by the primary ion source to release the inert gas atom in the sample target; ionizing the released inert gas atom by using an electron beam formed by the electron gun to form an inert gas ion; and analyzing a secondary ion containing the inert gas ion by using the mass analyzer and the ion detector to achieve measurement of the inert gas.

Abstract: A method of localizing brain regions for the purpose of guiding placement of electrodes and related implants is disclosed. The inventive method involves effecting a pulse in a patient's brain, temporally aligning readings taken from an electrode at various depths, measuring local field potentials at each depth during interstimulus intervals, performing a coherence analysis comparing the local field potential measurements of the different depths, and determining a corresponding brain region for the depths compared.

Abstract: Methods, systems and devices for managing humidity within an HVAC system including a nanostructured desiccant porous material configured to adsorb water from an inlet stream at a first air pressure and to release water from that material when subjected to a second air pressure when the second air pressure is lower than the first air pressure is located within a particular location so as to allow for the passage of wet air over the materials and allow adsorption of the water on to the material. When coupled with a vacuum pump water can be collected and released from the materials and the system, regenerating the material for future use and removing water from a stream at a significantly lower cost than existing processes.

Abstract: The present application provides bifunctional compounds of Formula (Ia): (Ia), or an enantiomer, diastereomer, stereoisomer, or pharmaceutically acceptable salt thereof, which act as protein degradation inducing moieties for one or mor of cyclin-dependent kinase 8 (CDK8) and cyclin-dependent kinase 19 (CDK19). The present application also relates to methods for the targeted degradation of CDK8 and/or CDK19 through the use of the bifumtional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to CDK8 and/or CDK19 which can be utilized in the treatment of disorders modulated by CDK8 and/or CDK19.

Abstract: An operation verifying apparatus of a first embodiment acquires a log indicating the content of a sequence of operations performed on a predetermined device, identifies corresponding functions from the log, and automatically generates a program based on the identified functions. Input data, which is to serve as an argument of each of these functions, is set. Execution sets as well as test scenarios are each structured by combining a program and input data. Then each execution set is continuously executed. As a result, an operation test using a test program is executed.

Abstract: Embodiments of the innovation relate to an emotional quality estimation device comprising a controller having a memory and a processor, the controller configured to execute a training engine with labelled training data to train a neural network and generate a classroom analysis machine, the labelled training data including historical video data and an associated classroom quality score table; receive a classroom observation video from a classroom environment; execute the classroom analysis machine relative to the classroom observation video from the classroom environment to generate an emotional quality score relating to the emotional quality of the classroom environment; and output the emotional quality score for the classroom environment.

Abstract: The present invention provides use of a photoperiod-sensitive genic male sterility mutant of cotton in crossbreeding or hybrid seed production. The fertility of the photoperiod-sensitive genic male sterility mutant of cotton is influenced by the photoperiod. The photoperiod characteristic of the photoperiod-sensitive genic male sterility mutant of cotton is that, the photoperiod-sensitive genic male sterility mutant of cotton shows normal fertility when the illumination time is shorter than 11.5 h and shows genic male sterility when the illumination time is longer than 12 h; the photoperiod-sensitive genic male sterility mutant of cotton is in a fertility change period when the illumination time is in a range of 11.5-12 h and has less pollen. The photoperiod-sensitive genic male sterility mutant of cotton is PSM1, and/or a photoperiod-sensitive genic sterile line obtained through selective breeding of hybridized and/or backcrossed and/or self-bred offsprings of the PSM1.

Abstract: An information processing method based on contextual signals and a prefrontal cortex-like network includes: selecting a feature vector extractor based on obtained information to perform feature extraction to obtain an information feature vector; inputting the information feature vector into the prefrontal cortex-like network, and performing dimensional matching between the information feature vector and each contextual signal in an input contextual signal set to obtain contextual feature vectors to constitute a contextual feature vector set; and classifying each feature vector in the contextual feature vector set by a feature vector classifier to obtain classification information of the each feature vector to constitute a classification information set. An information processing system based on contextual signals and a prefrontal cortex-like network includes an acquisition module, a feature extraction module, a dimensional matching module, a classification module and an output module.

Abstract: A cell therapy structure and method, including a matrix of fibers of a proteinaceous material and an electrically conductive material. The aligned fibers are spun from a combination the electrically conductive material, such as carbon nanotubes, and a fibroin material or a collagen material. A method of tissue engineering includes seeding a cell culture on a matrix of electrically conductive protein fibers, applying an electric current to the matrix to stimulate the cell culture, and applying the simulated cell culture to a tissue.

Abstract: A sparger includes a main pipe connecting inside and outside of a water tank having a storage space therein for storing cooling water, so as to define a flow path through which steam and air containing radioactive materials generated outside the water tank are discharged into the cooling water, a header part connected to one end portion of the main pipe located in the storage space, and having a storage chamber in which the steam and air transferred through the main pipe are collected, and a plurality of discharge nozzles disposed in a spacing manner, each having inlet and outlet formed on one end located in the storage chamber and another end located in the storage space, respectively, to discharge the steam and air from the storage chamber to the storage space, and at least some of the plurality of discharge nozzles protruding from the header part by different lengths.

Abstract: The present disclosure relates to a cracking device and a deposition apparatus including the same, and more particularly includes a source supply part for supplying a source gas, a cracking part for decomposing the source gas supplied from the source supply part, a distribution part disposed between the source supply part and the cracking part and distributing the source gas to the cracking part; and a heating element for heating the cracking part. The cracking part extends in a first direction, the cracking part has a first width in a second direction crossing the first direction, the cracking part has a first height in a third direction perpendicular to the first and second directions, and the ratio of the first width to the first height is about 2-20.

Abstract: The present disclosure relates to an anode electrode active material for a secondary battery containing nickel cobalt molybdenum oxide, an anode electrode for a secondary battery including the same, a secondary battery including the anode electrode for a secondary battery, and a method for manufacturing the same. The novel anode electrode material for a sodium secondary battery containing nickel cobalt molybdenum oxide according to the present disclosure allows intercalation/deintercalation reaction of sodium ion during charge/discharge and does not undergo significant volume change during the intercalation reaction because structure is maintained stably during repeated charge/discharge. As a result, electrode damage and electric short circuit are decreased and, thus, improved electrochemical characteristics can be achieved in long-life and high-rate capability.

Abstract: Provided is a method for controlling an interaction undo/redo interface. The method for controlling an interaction undo/redo interface includes causing interaction to be performed between a plurality of virtual objects created in a three-dimensional virtual space and a user, wherein the interaction is performed by recognition of the user's gesture, and activating the interaction undo interface or the interaction redo interface in response to a gesture not corresponding to the user's interaction gesture.