Abstract: Disclosed herein are a Bluetooth connection device and method based on estimation of a relative angle. The Bluetooth connection method based on estimation of a relative angle is performed by a Bluetooth connection device based on estimation of a relative angle, and includes estimating relative angles using relative angle estimation information included in packets received from one or more communication target devices that are scanned for a Bluetooth connection, determining a communication target device with which a communication link is to be established based on the estimated relative angles, and establishing a communication link through a Bluetooth connection to the determined communication target device, and reestablishing the communication link to any one of additional communication target devices, relative angles of which have been estimated, depending on a change in a relative angle to the communication target device with which the communication link has been established.
Type:
Application
Filed:
August 14, 2020
Publication date:
February 25, 2021
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Jae-Ho LEE, Do-Hyung KIM, Jin-Kyeong KIM, Cheol RYU, Hyung-Seok LEE
Abstract: The present disclosure provides a Farmington virus formulated to induce an immune response in a mammal against a tumour associated antigen. The Farmington virus may express an antigenic protein that includes an epitope from the tumour associated antigen. The Farmington virus may be formulated in a composition where the virus is separate from an antigenic protein that includes an epitope from the tumour associated antigen. The present disclosure also provides a prime:boost therapy for use in inducing an immune response in a mammal. The boost includes a Farmington virus, or a composition that includes a Farmington virus.
Type:
Application
Filed:
April 9, 2019
Publication date:
February 25, 2021
Applicant:
CHILDREN'S HOSPITAL OF EASTERN ONTARIO RESEARCH INSTITUTE INC.
Abstract: The present disclosure relates to a method for extracting chitin nanocrystals through electron beam irradiation comprising the steps of: (i) irradiating a chitin-based solid material with an electron beam; (ii) washing the chitin-based solid material subjected to electron beam irradiation; (iii) adding a basic solution to the washed chitin-based solid material; (iv) high-pressure homogenizing the chitin-based solid material dispersed in an aqueous system to which the basic solution is added, to prepare a suspension containing chitin nanocrystals.
Type:
Application
Filed:
August 21, 2020
Publication date:
February 25, 2021
Applicant:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Abstract: An oxide sintered body has metal elements of In, Ga, Zn, and Sn and contains Ga2In6Sn2O16, ZnGa2O4, and InGaZnO4. The contents of In, Ga, Zn, and Sn in the oxide sintered body satisfy the relations [Ga]?37 atomic %, [Sn]?15 atomic %, and [Ga]/([In]+[Zn])?0.7, where [In], [Ga], [Zn], and [Sn] represent ratios (atomic %) of In, Ga, Zn, and Sn with respect to all metal elements contained in the oxide sintered body, respectively.
Abstract: A traffic flow dynamic guiding method based on a region block includes: building communication connection with a cloud server by a vehicle-mounted terminal; performing data acquisition by the vehicle-mounted terminal, and uploading acquired data to the cloud server; receiving feedback of the cloud server by the vehicle-mounted terminal; which is including an accident occurring probability of a current automobile in a set range of a current road section; sending the probability to a driver in a human-computer interaction mode; receiving communication addresses, sent by the cloud server, of the surrounding vehicle-mounted terminals in the set range by the current vehicle-mounted terminal in order to build a connection relationship with the surrounding vehicle-mounted terminals; performing running and updating after the region block relationship is built; performing traffic flow guiding on traffic accident information and performing traffic flow guiding on official vehicles by using the region block relationship
Type:
Application
Filed:
April 12, 2018
Publication date:
February 25, 2021
Applicant:
SHANDONG PROVINCIAL COMMUNICATIONS PLANNING AND DESIGN INSTITUTE CO.,LTD
Inventors:
Lizhi ZHENG, Wenbo JI, Yiwu LI, Tao LI, Xibo LI, Bin HAO, Zengjin LI, Xufei JIAO, Jibin ZHU
Abstract: The present invention relates to a novel anticancer fusion protein and use thereof, and more particularly, provides a fusion protein in which a tumor necrosis factor (TNF) superfamily protein is linked to a self-assembled protein, which is capable of forming a protein nanocage by self-assembly of the self-assembled protein.
Type:
Application
Filed:
September 4, 2020
Publication date:
February 25, 2021
Applicants:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Min-Woo KIH, Eun Jung LEE, Yoo Soo YANG, Cherl Hyun JEONG, In-San KIM, Soyoun KIM
Abstract: Provided is a method for improving productivity in producing an organic compound in a bacterium that originally does not have an inherent ED pathway. In one aspect, provided is a transformant of a coryneform bacterium that is obtained by introducing the Entner-Doudoroff pathway into the coryneform bacterium as a host. In another aspect, provided is a transformant of a coryneform bacterium that is obtained by introducing, into a coryneform bacterium as a host a gene in which an enzyme having glucose-6-phosphate dehydrogenase activity is encoded, a gene in which an enzyme having 6-phosphogluconate dehydratase activity is encoded, and a gene in which an enzyme having 2-keto-3-deoxy-6-phosphogluconate aldolase activity is encoded.
Type:
Application
Filed:
March 27, 2019
Publication date:
February 25, 2021
Applicant:
RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH
Abstract: An apparatus and method for assessing cybersecurity vulnerabilities based on a serial port. The apparatus includes a vulnerability DB for storing vulnerability assessment items, a communication unit for configuring an environment for serial communication with an assessment target device and configuring a network environment, a vulnerability scanning unit for selecting a vulnerability assessment item for which cybersecurity vulnerability assessment is to be performed on the assessment target device, and performing scanning for checking the selected vulnerability assessment item on the assessment target device, a response analysis unit for analyzing a response of the assessment target device to the scanning, and setting one or more of an operating system, an application, and a protocol corresponding to the assessment target device, and a vulnerability presence determination unit for determining, using the set one or more of the operating system, application, and protocol, whether a vulnerability is present.
Type:
Grant
Filed:
July 23, 2018
Date of Patent:
February 23, 2021
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: The present application provides bifunctional compounds of Formula (I): or an enantiomer, diastereomer, or stereoisomer thereof, or pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, which act as protein degradation inducing moieties for protein kinases (e.g., Bcr-Abl). The present application also relates to methods for the targeted degradation of one or more protein kinases through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to one or more protein kinases which can be utilized in the treatment of disorders modulated by protein kinases.
Type:
Grant
Filed:
November 10, 2017
Date of Patent:
February 23, 2021
Assignee:
DANA-FARBER CANCER INSTITUTE, INC.
Inventors:
Nathanael S. Gray, James Bradner, Li Tan, Hai-Tsang Huang, Dennis Buckley, Georg Winter, Mette Ishoey Rosenbaum
Abstract: Disclosed herein are a dynamic scheduling method for guaranteeing Quality of Service QoS depending on network transmission traffic and a system using the same. The dynamic scheduling method includes assigning communication channels to respective nodes based on Identifications (IDs) of parent nodes corresponding to the respective nodes, setting priorities for assignment of time slots to the respective nodes in each quarter based on data traffic volumes corresponding to the respective nodes, and assigning time slots to the respective nodes in each quarter depending on the set priorities for assignment of the time slots.
Type:
Grant
Filed:
July 24, 2018
Date of Patent:
February 23, 2021
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Kyeong-Tae Kim, Bum-Ho Kim, Sang-Cheol Kim, Seon-Tae Kim, Hae-Yong Kim, Yu-Seung Ma, Pyeong-Soo Mah, Hui-Ung Park, Duk-Kyun Woo, Jeong-Woo Lee
Abstract: The present application provides bifunctional compounds of Formula (X): or an enantiomer, diastereomer, or stereoisomer thereof, or pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, which act as protein degradation inducing moieties for Bruton's tyrosine kinase (BTK). The present application also relates to methods for the targeted degradation of BTK through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to BTK which can be utilized in the treatment of disorders modulated by BTK.
Type:
Grant
Filed:
November 22, 2017
Date of Patent:
February 23, 2021
Assignee:
DANA-FARBER CANCER INSTITUTE, INC.
Inventors:
Nathanael S. Gray, Dennis Dobrovolsky, Hai-Tsang Huang
Abstract: A wireless communication terminal communicating wirelessly with a base wireless communication terminal and unassociated with the base wireless communication terminal is disclosed.
Type:
Grant
Filed:
December 15, 2017
Date of Patent:
February 23, 2021
Assignees:
WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., SK TELECOM CO., LTD.
Abstract: Arrays and substrates comprising a material, in particular capture agents and/or detectable targets, attached to the substrates along substantially parallel lines forming a barcoded pattern and related methods and systems.
Abstract: Disclosed are a selective colorimetric detection sensor and a colorimetric detection method for C6+ ions using size controlled label-free gold nanoparticles, which may be useful for the detection of toxic materials such as heavy metal ions in the environmental sector and the industry. Selective colorimetric sensor solution used therein is selectively reacted with only Cr6+ ions in trivalent chromium ions (Cr3+) and hexavalent chromium ions (Cr6+), and there is no interference effect resulting from other metal ions, and it is possible to very rapidly and precisely detect Cr6+ ions compared to the related art.
Type:
Grant
Filed:
July 29, 2016
Date of Patent:
February 23, 2021
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: The present disclosure provides a new mutant of Bacillus thuringiensis which is deposited under Accession number DSM 32419. The present disclosure also provides a method for manufacturing a growth promoter for promoting microalgal cell growth, including: (a) inoculating a mutant of Bacillus thuringiensis into a culturing medium to obtain a bacterial suspension, wherein the mutant of Bacillus thuringiensis is deposited under Accession number DSM 32419; (b) culturing the mutant of Bacillus thuringiensis in the bacterial suspension at least to a stationary phase to obtain a cultured medium of the mutant of Bacillus thuringiensis; and (c) performing a vacuum heating procedure on the cultured medium of the mutant of Bacillus thuringiensis to obtain the growth promoter for promoting microalgal cell growth, wherein the growth promoter for promoting microalgal cell growth contains active substances for promoting microalgal cell growth.
Type:
Grant
Filed:
March 16, 2018
Date of Patent:
February 23, 2021
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The invention discloses a ginseng-derived nanoparticle and a preparation method and application thereof. The ginseng-derived nanoparticle disclosed in the invention has a membrane structure, a particle size ranging from 150 to 500 nm and a peak particle size of 280 to 350 nm; and the ginseng-derived nanoparticle is prepared by multiple centrifugation, filtration and impurity removal. The ginseng-derived nanoparticle has good application prospects in developing drugs for preparing natural immunopotentiators and for preparing natural anti-tumor drugs.
Type:
Grant
Filed:
June 19, 2017
Date of Patent:
February 23, 2021
Assignee:
JIANGSU PROVINCE INSTITUTE OF TRADITIONAL CHINESE MEDICINE
Abstract: The present invention relates to a method for transmitting an aggregate MPDU and a response frame thereto and a wireless communication terminal using the same, and more particularly, to a wireless communication method and a wireless communication terminal for setting various formats of the aggregate MPDU and the response frame thereto and performing an efficient data communication by using the same.
Type:
Grant
Filed:
June 21, 2019
Date of Patent:
February 23, 2021
Assignees:
WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., SK TELECOM CO., LTD.
Abstract: The present invention provides asymmetrical duplex RNA molecules that are capable of effecting sequence-specific gene silencing. The RNA molecule comprises a first strand and a second strand. The first strand is longer than the second strand. The RNA molecule comprises a double-stranded region formed by the first strand and the second strand, and two ends independently selected from the group consisting of 5?-overhang, 3?-overhang, and blunt end. The RNA molecules of the present invention can be used as research tools and/or therapeutics.
Type:
Grant
Filed:
February 20, 2019
Date of Patent:
February 23, 2021
Assignee:
1GLOBE HEALTH INSTITUTE LLC
Inventors:
Chiang Jia Li, Xiangao Sun, Harry Rogoff, Youzhi Li
Abstract: A terahertz security check method and system may include: a terahertz scanning device collecting a terahertz original image of a human body under test, and sending the same to a central server that identifies the terahertz original image, and determines whether the human body under test carries an article. If so, the image is marked with the position of the article and sent to a monitoring terminal. The monitoring terminal correspondingly marking the position of the article on a pre-stored human body cartoon image, and displaying the terahertz original images before and after marking to monitoring personnel, so that the monitoring personnel determine whether the central server has an identification error; and if so, the monitoring terminal changing a marker on the human body cartoon image, and sending the changed cartoon image to a client of security check personnel for displaying.
Type:
Grant
Filed:
December 21, 2016
Date of Patent:
February 23, 2021
Assignees:
CHINA COMMUNICATION TECHNOLOGY CO., LTD., SHENZHEN INSTITUTE OF TERAHERTZ TECHNOLOGY AND INNOVATION