Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Abstract: An operation method of a terminal may comprise receiving information on one CG configuration for uplink transmission from a base station; obtaining common time domain resource allocation information for combinations of RB sets based on the information on the one CG configuration; obtaining frequency domain resource allocation information for each of the combinations of the RB sets based on the information on the one CG configuration; determining a number of PRBs to which an uplink channel is mapped based on the frequency domain resource allocation information corresponding to one combination of the combinations; determining a TBS based on the common time domain resource allocation information and the number of PRBs; and transmitting a TB having the TBS to the base station within the one combination through the uplink channel according to the common time domain resource allocation information and the frequency domain resource allocation information.

Abstract: A composite film includes a fiber structure layer and a filling material layer. The fiber structure layer has a plurality of fibers and a first melting temperature. The filling material layer is disposed on the fiber structure layer and has a second melting temperature. At least one of the fibers extends into the filling material layer, and the first melting temperature is greater than the second melting temperature. Wherein the fiber structure layer includes a polymer selected from a group consisting of PI, polyurethanes (PU), polyamide, polybenzimidazole, polycarbonate, polyacrylonitrile, polyethyleneterephtalate, poly(vinylidenefluoride), poly(4-methylpentene) (TPX), and the arbitrary combinations thereof; the filling material layer includes polyolefin or polyester.

Abstract: A method and apparatus for reconstructing an image using an extended neural network is provided. The method includes receiving an input image and reconstructing an output image from the input image using a neural network meeting a predetermined frame constraint. The reconstructing includes transforming the input image into signals corresponding to different frequencies, adjusting coefficients of the transformed signals using a nonlinear function, reconstructing the adjusted coefficients, and inversely transforming all coefficients determined using the reconstructed coefficients into the output image.

Abstract: A radioactive cesium adsorbent includes photocatalyst particles and Prussian blue. The ferric ions of the Prussian blue are reduced to ferrous ions by activation of the photocatalyst particles. A method of removing radioactive cesium using the radioactive cesium adsorbent includes preparing a composition comprising photocatalyst particles and Prussian blue; preparing a precursor solution by mixing radioactive cesium and the composition prepared in the preparing of a composition; and reducing ferric ions of the Prussian blue to ferrous ions by activating the photocatalyst particles in the precursor solution prepared in the preparing of a precursor solution.

Abstract: An all-solid-state secondary battery including: a positive electrode layer; a negative electrode layer; and a solid electrolyte layer between the positive electrode layer and the negative electrode layer, wherein the positive electrode layer includes a sulfur-containing positive electrode active material, a halogen-containing sulfide solid electrolyte, and a conductive carbon material, and wherein the sulfur-containing positive electrode active material includes elemental sulfur and a transition metal disulfide.

Abstract: Disclosed is a linear expander includes: a body portion including a suction hole through which a fluid having a first pressure flows in, a discharge hole through which the fluid flows out with a second pressure that is lower than the first pressure, and first and second holes connecting an expansion space formed between the suction hole and the discharge hole, a first linear generating portion and a second linear generating portion respectively causing pistons provided in the first hole and the second hole to linearly reciprocate to generate an induced electromotive force with an expansion force generated when the fluid having the first pressure expands to the fluid having the second pressure, a suction valve opening and closing the suction hole, and a discharge valve and closing the discharge hole.

Abstract: According to an aspect of the present invention, there is provided a pattern structure inspection method including irradiating a wave from a wave source onto a sample including a pattern region in which a structure having a certain pattern is provided on a substrate, collecting speckle data generated due to multiple scattering of the wave in the pattern region, by using a data collector, and analyzing whether the structure of the pattern region has a defect, by comparing the collected speckle data to reference speckle data.

Abstract: The invention provides heterocyclic compounds of formula A, B, and C as described herein that inhibit monocarboxylate transporters, such as MCT1 and MCT4. Compounds of the invention can be used for treatment of a condition in a patient, wherein the condition is characterized by the heightened activity or by the high prevalence of MCT1 and/or MCT4, such as cancer or type II diabetes.

Abstract: The present invention relates to an antibody specifically bound to mesothelin (MSLN), a nucleic acid encoding the antibody, a vector and a host cell including the nucleic acid, a method for producing the antibody, and a pharmaceutical composition for treating cancer or tumor including the antibody as an active ingredient. The antibody specifically bound to the mesothelin according to the present invention has high affinity and specificity to an antigen, such that it is possible to develop an antibody effectively usable for treatment or diagnosis of cancer or tumor diseases.

Abstract: The present invention relates to a method of producing metal nanoparticles and metal sulfide nanoparticles using a recombinant microorganism co-expressing metallothionein and phytochelatin synthase, which are heavy metal-adsorbing proteins, and to the use of metal nanoparticles and metal sulfide nanoparticles synthesized by the method. The present invention provides a method for synthesizing metal nanoparticles which have been difficult to synthesize by conventional biological methods. The present invention makes it possible to synthesize metal nanoparticles in an environmentally friendly and cost-effective manner, and also makes it possible to synthesize metal sulfide nanoparticles. In addition, even metal nanoparticles which could have been produced by conventional chemical or biological methods are produced in a significantly increased yield by use of the method of the present invention.

Abstract: The agent for inhibiting inflammation promoted by GM3 of the present invention comprises a substance that inhibits inflammation promoted by GM3 as an active ingredient. The substance which inhibits inflammation promoted by GM3 is preferably a ganglioside having 2 or more of sialic acids. The ganglioside having 2 or more of sialic acids is at least one kind of ganglioside selected from the group consisting of GD1c, GD1a, GT1a, GD3, GD2, GD1b, GT1b, GQ1b, GT3, GT2, GT1c, GQ1c, and GP1c. Further, the substance which inhibits inflammation promoted by GM3 has a structure represented by the following formula (1): [In the formula (1), R1 represents a glycan constituting ganglioside GM3, R2—C(?O)— represents a fatty acid residue having 18 or less of carbon atoms, or an unsaturated fatty acid residue having 20 or more of carbon atoms.

Abstract: A polycrystalline form of a dehydrophenylahistin-like compound, and a manufacturing and purification method and application thereof. A (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)deuteromethylene]piperazine-2,5-dione monohydrate crystal and a (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylene]piperazine-2,5-dione monohydrate crystal are more competitive crystalline forms with stable quality. The manufacturing and purification method is simple and easy to operate, and can effectively control the generation of a trans-isomer contaminant to obtain a high purity product. The polycrystalline form of the dehydrophenylahistin-like compound has a certain value in an application for manufacturing an antitumor pharmaceutical product.

Abstract: Disclosed herein are an autonomous driving robot apparatus and an autonomous driving method. The autonomous driving method of the autonomous driving robot apparatus includes receiving task information for autonomous driving from a server device for supporting autonomous driving; creating a route for autonomous driving based on the task information and performing autonomous driving; and selecting an autonomous driving operation corresponding to any one of moving, waiting, and wandering when arriving at a preset destination by performing autonomous driving along the route.

Abstract: The present invention discloses an electromechanical compound transmission device for a tracked vehicle. The electromechanical compound transmission device includes a front transmission mechanism, a power coupling mechanism, an independent drive mechanism, and convergent planetary gearsets arranged on both sides of the power coupling mechanism. The present invention can not only implement driving, steering, and other functions of a vehicle, but also provide sufficient electric energy for a vehicle-mounted device. In other words, a series mode can be adopted to satisfy a torque output requirement, and is mainly used for low and medium-low speed driving, as well as reverse driving and climbing steep slopes; and a series-parallel mode can also be adopted to satisfy requirements of high and medium-high speed driving, and can achieve relatively high transmission efficiency and fuel economy.

Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences especially for use as to nucleotide repeat disorders. Provided are delivery systems and tissues or organ which are targeted as sites for delivery especially for use as to nucleotide repeat disorders. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex or system especially for use as to nucleotide repeat disorders, as well as methods for the design and of such. Also provided are methods of directing CRISPR complex or system formation in eukaryotic cells especially for use as to nucleotide repeat disorders including with consideration of specificity for target recognition and avoidance of toxicity and editing or modifying a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.

Abstract: An enhanced HFET, comprising a HFET device body.

Abstract: The present disclosure provides a LADCP-USBL combined observation and data processing method and an apparatus. According to one embodiment, an exemplary method may include: acquiring bottom tracking data from the LADCP, position trajectory data collected by the USBL, and ocean current data collected by the LADCP; removing abnormal data points from the position trajectory data; performing azimuth angle correction on the position trajectory data according to the bottom tracking data to determine a movement velocity of the LADCP; and calculating an absolute ocean current velocity according to the movement velocity of the LADCP and the ocean current data.

Abstract: Phase modulated Optical Parametric Amplification Imaging (p-OPA), can be used to determine the magnitude and the sign of the second-order nonlinear susceptibility of a material, and its spatial variation.

Abstract: Modified asphalt particles contain asphalt and a modifier. The modifier comprises poly-sulfur and free sulfur. The sulfur element accounts for 10-40 weight percent of the total amount of the modified asphalt particles, and the poly-sulfur accounts for 30-70 weight percent of the total amount of the sulfur element. The total particle size of the modified asphalt particle is smaller than or equal to 150 ?m. The modified asphalt particles have an excellent high temperature performance, and can be used for preparing drilling fluids. Water-in-oil based drilling fluid obtained from the modified asphalt particles has low plastic viscosity, high dynamic shear force, high dynamic plastic ratio, and high emulsion-breaking voltage, and improves the high temperature resistance and cutting carrying capability of a system.