Patents Assigned to INSTITUTE
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Publication number: 20230072809Abstract: The present disclosure relates to immunogenic compositions comprising tetanus, diphtheria, and acellular pertussis (Tdap) antigens, and a toll-like receptor 9 (TLR9) agonist, such as oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions may further comprise an aluminum salt adjuvant to which the Tdap antigens are adsorbed. The immunogenic compositions are suitable for active booster immunization against tetanus, diphtheria, and pertussis in an individual in need thereof.Type: ApplicationFiled: March 9, 2021Publication date: March 9, 2023Applicants: Dynavax Technologies Corporation, Serum Institute of India Private LimitedInventors: John D. CAMPBELL, Robert L. COFFMAN, Randall N. HYER, Robert S. JANSSEN, David NOVACK, Martin GOHLKE, Maureen URBAN, Sunil GAIROLA, Umesh SHALLIGRAM, Manish GAUTUM, Harish RAO
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Publication number: 20230077033Abstract: A fuel cell catalyst including a conductive carrier and core-shell nanoparticles supported on the carrier. The core includes platinum and a transition metal and the shell includes a secondary metal. An electrochemical specific activity measured at a voltage of 0.05 V to 1.05 V (vs. RHE) in a potential range, at a scan rate of 5 mV/s and a rotation rate of 1,600 rpm in an O2-saturated 0.1 M HClO4 electrolyte solution is 0.3 mA/cm2 to 0.6 mA/cm2, and a mass activity is 0.05 mA/?g to 0.08 mA/?g.Type: ApplicationFiled: August 25, 2022Publication date: March 9, 2023Applicants: HYUNDAI MOBIS CO., LTD., KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Eun Young YOU, Yun Sik KANG, Dae Jong YOU, Sung Chul LEE, Sung Jong YOO, Se Hyun LEE, Jue Hyuk JANG, Eung Jun LEE
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Publication number: 20230071059Abstract: An imaging lens system includes a first lens, a second lens, a third lens, a fourth lens, a fifth lens, a sixth lens, and a seventh lens, sequentially disposed from an object side. A field of view (FOV) of the imaging lens system according to an embodiment is wider than 85 degrees and narrower than 160 degrees. In the imaging lens system according to an embodiment, a distance (TTL) from an object-side surface of the first lens to an imaging plane is greater than 6.0 mm and less than 9.0 mm.Type: ApplicationFiled: January 6, 2022Publication date: March 9, 2023Applicants: SAMSUNG ELECTRO-MECHANICS CO., LTD., KUMOH NATIONAL INSTITUTE OF TECHNOLOGY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Tae Yeon LIM, Yong Joo JO, Phil Ho JUNG, Jae Myung RYU
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Publication number: 20230076251Abstract: Disclosed are a method, an electronic apparatus for detecting tampering audio and a storage medium. The method includes: acquiring a signal to be detected, and performing a wavelet transform of a first preset order on the signal to be detected so as to obtain a first low-frequency coefficient and a first high-frequency coefficient corresponding to the signal to be detected, the number of which is equal to that of the first preset order; performing an inverse wavelet transform on the first high-frequency coefficient having an order greater than or equal to a second preset order so as to obtain a first high-frequency component signal corresponding to the signal to be detected; calculating a first Mel cepstrum feature of the first high-frequency component signal in units of frame, and concatenating the first Mel cepstrum features of a current frame signal and a preset number of frame signals.Type: ApplicationFiled: February 8, 2022Publication date: March 9, 2023Applicant: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCESInventors: Jianhua TAO, Shan LIANG, Shuai NIE, Jiangyan YI
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Publication number: 20230071946Abstract: The present disclosure provides a package structure, an antenna module, and a probe card. The package structure includes a connection member and a first redistribution structure disposed on the connection member. The connection member includes a conductive connector and an insulation layer surrounding the conductive connector. The first redistribution structure includes a first dielectric layer, and a first wiring pattern, and a first device. The first dielectric layer is disposed on the connection member. The first wiring pattern is disposed in the first dielectric layer. The first device is disposed above the first dielectric layer and is electrically connected to the conductive connector.Type: ApplicationFiled: March 30, 2022Publication date: March 9, 2023Applicant: Industrial Technology Research InstituteInventors: Chieh-Wei Feng, Tai-Jui Wang, Jui-Wen Yang, Tzu-Yang Ting
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Publication number: 20230071976Abstract: A virtual function performance analysis system and an analysis method thereof are disclosed. The virtual function performance analysis method includes: monitoring performance of at least one virtual function of a virtual network function application on a virtual platform having at least one physical resource and at least one virtual resource; monitoring and recording an actual value of each of performance indicators of each of physical resources, each of virtual resources and each of virtual functions; comparing the actual value of each of performance indicators with the associated expected value and/or threshold value to obtain a comparison result; and analyzing system performance according to the comparison result.Type: ApplicationFiled: December 2, 2021Publication date: March 9, 2023Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yu-Wei LEE, Ming-Hung HSU, Chih-Kuan YEN
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COMPOSITION FOR PREVENTING OR TREATING COGNITIVE DYSFUNCTION INCLUDING INHIBITOR OR MECP2 EXPRESSION
Publication number: 20230075981Abstract: Disclosed is a composition for preventing or treating a degenerative brain disease. The composition includes, as an active ingredient, a MECP2 inhibitor for treating the degenerative brain disease, a polynucleotide encoding the MECP2 inhibitor or a recombinant virus containing the MECP2 inhibitor. The composition is useful for the treatment of a degenerative brain disease (particularly Alzheimer's syndrome) caused by beta-amyloid. In addition, the composition is effective in improving or ameliorating deterioration of cognitive functions and social deficits caused by Alzheimer's syndrome.Type: ApplicationFiled: May 16, 2022Publication date: March 9, 2023Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Heh-In IM, Sangjoon LEE, Ji Eun CHOI -
Publication number: 20230076741Abstract: A handheld microsurgical robot according to an embodiment of the present disclosure includes a tool, and a driving mechanism configured to detachably fix the tool and operate the tool, wherein the driving mechanism includes a platform supporting the tool, a plurality of driving assemblies connected to the platform and configured to operate the platform; and a base configured to fix the plurality of driving assemblies, wherein each of the plurality of driving assemblies is capable of a linear motion with respect to the base and is capable of a rotational motion with respect to the base, wherein a position and an angle of the platform with respect to the base are controlled by the linear motion of each of the plurality of driving assemblies.Type: ApplicationFiled: October 19, 2021Publication date: March 9, 2023Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sungwook YANG, Eunchan KIM, Ingu CHOI
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Publication number: 20230073419Abstract: Schemes are described for conductor and coolant placement in stacked-plate superconducting magnets, including arranging coolant channels and conducting channels within the plates on opposing faces. If the two types of channels are aligned with one another across the plate stacks, the plates may be stacked such that the cooling channel in one plate is adjacent to the conducting channel of the neighboring plate. By stacking a number of these plates, therefore, cooling may be supplied to each conducting channel through the cooling channels of each neighboring plate. Moreover, by aligning the two types of channels, the stacks of plates may have improved mechanical strength because mechanical load paths through the entire stack that do not pass through any of the channels may be created. This arrangement of channels may produce a very strong stack of plates that can withstand high Lorentz loads.Type: ApplicationFiled: March 25, 2021Publication date: March 9, 2023Applicants: Massachusetts Institute of Technology, Commonwealth Fusion Systems LLCInventors: Brian LABOMBARD, Robert MUMGAARD, William BECK, Jeffrey DOODY
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Patent number: 11597743Abstract: The present invention relates to methods of treating bacterial infections and cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula I.Type: GrantFiled: January 11, 2019Date of Patent: March 7, 2023Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: William M. Clemons, Michio Kurosu
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Patent number: 11601677Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method of decoding an image includes receiving a bitstream in which the image is encoded; obtaining index information for specifying a block division type of a current block in the image; and determining the block division type of the current block from a candidate group pre-defined in the decoding apparatus. The candidate group includes a plurality of candidate division types, including at least one of a non-division, a first quad-division, a second quad-division, a binary-division or a triple-division. The method also includes dividing the current block into a plurality of sub-blocks; and decoding each of the sub-blocks with reference to syntax information obtained from the bitstream.Type: GrantFiled: January 20, 2022Date of Patent: March 7, 2023Assignee: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.Inventor: Ki Baek Kim
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Patent number: 11598847Abstract: A light detection and ranging (LiDAR) apparatus and a method of operating the LiDAR apparatus are provided. The LiDAR apparatus includes a light transmitter configured to irradiate a laser pulse towards an object, the laser pulse being generated based on a reference signal; a light receiver configured to receive the laser pulse reflected from the object and configured to obtain a first signal from the received laser pulse; and at least one processor configured to convert the first signal and the reference signal respectively into unipolar signals and configured to detect a flight time of the laser pulse based on a correlation between the converted first signal and the converted reference signal.Type: GrantFiled: August 28, 2019Date of Patent: March 7, 2023Assignees: SAMSUNG ELECTRONICS CO., LTD., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jungwoo Kim, Youngjoon Jo, Kyihwan Park
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Patent number: 11597751Abstract: Glycan-binding proteins, and compositions thereof, are generally described, including methods of making and using such proteins. The proteins may include scaffolds based on easily evolvable DNA-binding proteins, with binding sites able to specifically bind to mono- or disaccharides, such as monosaccharide-binding determinants, disaccharide-binding determinants, more complex carbohydrates, etc. In certain aspects, a protein may be generated starting from a small DNA-binding protein, such as Sso7d. Such glycan-binding proteins may have numerous applications, including in enzyme-linked immunosorbent assays (ELISAs), glycan characterization, cell selection, flow cytometry, histology, imaging, arrays, affinity purification, enzyme-linked visualization, binding to a target for pharmaceutical purposes, etc.Type: GrantFiled: March 13, 2020Date of Patent: March 7, 2023Assignee: Massachusetts Institute of TechnologyInventors: Barbara Imperiali, Cristina Zamora, Elizabeth Ward
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Patent number: 11597098Abstract: An assistive robot system includes a lifting mechanism, a movable arm assembly, a processing device, and a non-transitory, processor-readable storage medium in communication with the processing device. The processing device transmits a command to the lifting mechanism to cause the lifting mechanism to move the movable arm assembly such that a container is gripped within the movable arm assembly, transmits a first one or more signals to the movable arm assembly to cause the movable arm assembly to extend in a system longitudinal direction such that the movable arm assembly grips the container. The movable arm assembly is positioned at a release location and transmits a second one or more signals to the movable arm assembly to cause the movable arm assembly to extend in a system lateral direction such that the container gripped within the movable arm assembly is released from the movable arm assembly at the release location.Type: GrantFiled: September 4, 2019Date of Patent: March 7, 2023Assignee: Toyota Research Institute, Inc.Inventors: Aimee S. Goncalves, Christopher Gidwell, Joseph Bondaryk, Paul W. Baim, Toffee Albina
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Patent number: 11597659Abstract: Disclosed is a device for treating high-concentration organic wastewater by catalyst hydrothermal gasification, including a CHG reactor, a temporary wastewater storage tank and a condensing heat exchanger which are sequentially in loop connection. The CHG reactor includes a shell, a thermocouple, a water distribution device, and a packing support. The device of the present disclosure can quickly convert the high-concentration organic wastewater into clean energy or harmless gas at a low temperature under the action of a catalyst, so that the energy consumption of a treatment process is greatly reduced, and the treatment efficiency is improved. The device has potential application prospect.Type: GrantFiled: March 20, 2021Date of Patent: March 7, 2023Assignees: Nanjing University, Nanjing University-International Research Institute of Environmental IndustriesInventors: Lu Lv, Linping Wang, Jie Rui, Qianlin Huang, Jingsheng Xu, Weiming Zhang, Bingcai Pan
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Patent number: 11600363Abstract: Provided is a pedo-transfer function (PTF)-based method for predicting a target soil property. Based on the collection of a multi-source soil dataset and environmental variables, a dataset containing all measured information is divided. Second-level regions are obtained by zoning according to the spatial variation in soil properties. An optimal independent variable set of PTFs in different regions is obtained by screening. Then, linear fitting and nonlinear fitting of the PTFs are performed for different zones separately. By comparing the accuracy of different functions between different zones, optimal PTFs oriented toward sampling sites are selected, so as to build a database including soil sampling sites. Further, regional independent variable layers are constructed by means of machine learning, to establish region-oriented PTFs; and a spatial distribution map of the target soil property and content for a target region is produced.Type: GrantFiled: January 16, 2022Date of Patent: March 7, 2023Assignee: INSTITUTE OF SOIL SCIENCE, CHINESE ACADEMY OF SCIENCESInventors: Xiaodong Song, Ganlin Zhang, Decheng Li, Feng Liu, Huayong Wu, Fei Yang, Jinling Yang, Yuguo Zhao
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Patent number: 11596114Abstract: Disclosed is a floating island construction method for overall transplantation of sandy soil plants, the method comprising the following steps: separation from a surrounding soil body; construction of a buoyancy tank device (13); and waterproof construction, so as to construct a plant floating island from plants to be transplanted in a reservoir area. The floating island protects all the root systems of the plants and most of the undisturbed soil, improves the survival rate, preserves the unique landscape of an original habitat, and can be constructed at the same time as water conservancy project construction, which saves on the construction period, saves costs, and is convenient for on-site overall scheduling.Type: GrantFiled: March 3, 2021Date of Patent: March 7, 2023Assignee: CHINA RENEWABLE ENERGY ENGINEERING INSTITUTEInventors: Hao Jiang, Bo Lu, Baiyan Chen
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Patent number: 11598518Abstract: An enhanced boiling apparatus includes a substrate having at least one heated region, at least one outer surface, and one or more asymmetric shaped cavities extending into the substrate along the at least one outer surface. Each of the one or more asymmetric shaped cavities has a sidewall which intersects at a corner with a bubble pathway surface with a different slope from the sidewall. Each of the asymmetric shaped cavities is configured to non-gravitationally direct fluid that is moving along the sidewall out along the bubble pathway surface.Type: GrantFiled: June 3, 2020Date of Patent: March 7, 2023Assignee: Rochester Institute of TechnologyInventor: Satish G. Kandlikar
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Patent number: 11596934Abstract: Disclosed are a pincer-type ligand having a structurally rigid acridane structure and a metal complex consisting of the pincer-type ligand and a metal bound to each other, and exhibiting high reactivity and stability during a variety of bonding activation reactions. T-shaped complexes can be prepared from acriPNP(4,5-bis(diisopropylphosphino)-2,7,9,9-tetramethyl-9H-acridin-10-ide), which is a pincer-type PNP ligand having an acridane structure, and metal complexes, which can be structurally rigid and thus exhibit excellent reactivity and stability based on minimized structural change thereof, can be prepared by introducing an acridane structure into the backbone thereof. The PNP ligand is structurally stable and has novel chemical properties, as compared to conventional similar ligands, and thus can be utilized in a wide range of catalytic reactions and material chemistry.Type: GrantFiled: February 2, 2021Date of Patent: March 7, 2023Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Yunho Lee, Changho Yoo, Jonghoon Choi
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Patent number: 11598917Abstract: A silicon nitride phased array chip based on a suspended waveguide structure, which includes a silicon nitride waveguide area and a suspended waveguide area. The silicon nitride waveguide area includes a silicon substrate, a silicon dioxide buffer layer, a silicon dioxide cladding layer and a silicon nitride waveguide-based core layer. The silicon nitride waveguide-based core layer includes an optical splitter unit, a first curved waveguide, a thermo-optic phase shifter and a spot-size converter. The suspended waveguide area includes a second curved waveguide and an array grating antenna.Type: GrantFiled: June 3, 2021Date of Patent: March 7, 2023Assignees: Chongqing Institute of East China Normal University, SHANGHAI LANGYAN OPTOELECTRONICS TECHNOLOGY CO., LTD., East China Normal UniversityInventors: Heping Zeng, Jijun Feng, Mengyun Hu, Xiaojun Li, Qinggui Tan, Jinman Ge