Patents Assigned to INSTITUTE
  • Patent number: 11474008
    Abstract: An exhaust gas dilution device according to an exemplary embodiment of the present invention includes a head part, ejector unit, a nozzle part, and a dilution part. The head part has a space part into which an exhaust gas flows and a through-hole formed through the center axis direction to be connected to the space part. The ejector unit is coupled to the head part and has a first discharge hole formed passing through the center axis direction to be connected to the through-hole and connected to a first inlet to which primary dilution air is supplied. The nozzle part is inserted into a first discharge hole through the through-hole and has a second discharge hole that penetrates in the center axis direction so that the exhaust gas flowed into the space part is sucked and ejected into the first discharge hole as the primary dilution air moves through the first discharge hole.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: October 18, 2022
    Assignee: KOREA INSTITUTE OF MACHINERY & MATERIALS
    Inventors: Bangwoo Han, Chang Gyu Woo, Hak Joon Kim, Yong-Jin Kim
  • Patent number: 11472868
    Abstract: Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4, these antibodies having improved potency and breadth.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: October 18, 2022
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE ROCKEFELLER UNIVERSITY
    Inventors: Ron Diskin, Pamela J. Bjorkman, Michel C. Nussenzweig, Johannes Scheid
  • Patent number: 11472883
    Abstract: The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human OX40 and modulate OX40 activity, e.g., enhance, activate, or induce OX40 activity, or reduce, deactivate, or inhibit OX40 activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., enhances, activates, or induces OX40 activity. Also provided are methods for treating autoimmune or inflammatory diseases or disorders, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., reduces, deactivates, or inhibits OX40 activity.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: October 18, 2022
    Assignees: Agenus Inc., Memorial Sloan-Kettering Cancer Center, Ludwig Institute for Cancer Research Ltd.
    Inventors: Marc Van Dijk, Ekaterina V. Breous-Nystrom, Volker Seibert, Gerd Ritter, David Schaer, Daniel Hirschhorn-Cymerman, Taha Merghoub, Hao Tang, David A. Savitsky, Jeremy Waight, Nicholas S. Wilson
  • Patent number: 11472915
    Abstract: Porous compositions such as flexible polymers with side chain porosity are generally provided. In some embodiments, the composition comprises a flexible polymer backbone and a plurality of rigid side chains. In some embodiments, the rigid side chains form pores. In some embodiments, the rigid side chains may comprise two or more [2.2.2] bicyclic cores (e.g., formed by a ring opening metathesis polymerization. The compounds and methods described herein may be useful in various applications including, for example, gas separation.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: October 18, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Yuan He, Zachary Smith, Sharon Lin, Francesco Maria Benedetti
  • Patent number: 11472469
    Abstract: An electric power steering device including a column actuator disposed on a column side of the intermediate shaft and outputting a column assist torque; a rack actuator disposed on a rack side of the intermediate shaft and outputting a rack assist torque; a column torque sensor coaxially disposed with the steering shaft and detecting a column torsion torque; a rack torque sensor coaxially disposed with the intermediate shaft and detecting a rack torsion torque; and a calculator calculating instruction values of the column assist torque and the rack assist torque based on the torsion torques.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: October 18, 2022
    Assignees: DENSO CORPORATION, NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Shuji Kuramitsu, Hiroyasu Otake, Ryo Kano, Yoshifumi Morita, Hironao Watanabe, Takayuki Kato
  • Patent number: 11475633
    Abstract: A three-dimensional (3D) image dynamic correction evaluation and auxiliary design method for orthotics includes the following steps. 3D scanning information of the human body is obtained. A plurality of 2D images of the human body is obtained for identification, and the pixel values of the 2D images are calculated so as to synthesize an original 3D spine curve. The 2D images of the human body and the 3D scan information are synthesized. An image deformation prediction and correction method of body shape is used to generate a deformed body shape of the human body. A spine material properties and mechanical model prediction method is used to predict parameters of the position, direction and magnitude of the force applied by an orthotics to the human body according to the deformed body shape.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: October 18, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Po-Fu Yen, Zhong-Yi Haung, Shang-Yi Lin, Tian-Li Yu, Tzong-Ming Wu, Tsung-Wen Tsai
  • Patent number: 11476945
    Abstract: Disclosed is a multi-channel optical signal generating apparatus, which includes a CW laser that generates a single optical signal, an optical signal processor unit that processes the single optical signal, an oscillator that generates an electrical signal, and an electrical signal processor unit that generates a modulation signal, based on the electrical signal, and the optical signal processor unit includes ‘n’ optical circulators, at least one optical intensity modulator, (m-1) optical phase modulators, and ‘n’ BiODLs, the electrical signal processor unit includes a RF power divider which divides the electrical signal, and ‘m’ RF power amplifiers, the RF power divider divides the electrical signal into ‘m’ divided electrical signals, and the optical signal processor unit modulates and outputs the single optical signal by the at least one optical intensity modulator and the (m-1) optical phase modulators, based on the ‘m’ divided electrical signals divided from the RF power divider.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: October 18, 2022
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sang-Pil Han, Sungil Kim, Jaegyu Park, Minhyup Song
  • Patent number: 11473219
    Abstract: The present application provides methods for producing polybenzimidazole carbon fiber that does not require infusibilization treatment.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: October 18, 2022
    Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Toshihira Irisawa, Hiroaki Hatori, Yasushi Soneda, Masaya Kodama
  • Patent number: 11471825
    Abstract: Processes and systems for the capture of CO2 from a CO2-containing gas stream are provided. The CO2-containing gas stream is passed to a membrane contactor absorber wherein the CO2-containing gas contacts or passes a first side of a membrane element while a CO2 selective solvent with a viscosity between 0.2 and 7 cP contacts, passes or flows on second side of the membrane, opposed to the first side. The CO2 permeates through the hollow fiber membrane pores and is chemically absorbed into the solvent.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: October 18, 2022
    Assignee: GAS TECHNOLOGY INSTITUTE
    Inventors: Shiguang Li, Travis Pyrzynski, Howard Meyer, Naomi Klinghoffer, Timothy Tamale
  • Patent number: 11472696
    Abstract: The present disclosure belongs to the field of geological exploration, and particularly relates to a seismic acquisition system and a sensor based on an MEMS sensor with low power consumption, so as to solve the problem that the existing seismic wave acquisition technology cannot balance high accuracy and low power consumption when the MEMS sensor is used. The present disclosure comprises: the MEMS sensor is used for receiving seismic wave signals and outputting MEMS sensor electrical signals; a common-mode voltage adjustment module is used for adjusting the MEMS sensor signals to be within the input range of common-mode voltage of a readout circuit, so as to obtain low voltage MEMS sensor signals. In the present disclosure, high voltage ensures the detection accuracy of the MEMS sensor; and low voltage is supplied to the readout circuit, thereby reducing the power consumption of the overall seismic acquisition system.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: October 18, 2022
    Assignee: INSTITUTE OF GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Zongwei Li, Jing Liu, Yongjian Zhou, Changchun Yang, Kedu Han
  • Patent number: 11473100
    Abstract: Isolated DNA of the Wtk1 gene or a functional equivalent capable of conferring resistance to stripe rust, is provided, as well as artificial vectors comprising same, proteins encoded by same and nucleic acid molecules for detecting same. Transgenic plants, as well as cells, seeds, and tissue therefrom which express the Wtk1 gene or a functional equivalent thereof are also provided.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: October 18, 2022
    Assignees: CARMEL HAIFA UNIVERSITY ECONOMIC CORPORATION LTD., NATURAL RESOURCES INSTITUTE FINLAND (LUKE)
    Inventors: Tzion Fahima, Abraham B. Korol, Lin Huang, Dina Raats, Valentyna Klymiuk, Zeev Frenkel, Alan Howard Schulman, Elitsur Yaniv, Andrii Fatiukha
  • Patent number: 11473453
    Abstract: A reciprocating piston engine, comprising an engine block having a piston cylinder; a piston disposed in the piston cylinder; an intake port to the piston cylinder, an intake valve to open and close the intake port to the piston cylinder; a rotatable crankshaft; a flywheel connected to the crankshaft which is rotatable with the crankshaft, the flywheel having a circumferential profile; and a cam lobe forming a portion of the circumferential profile of the flywheel wherein, during rotation of the crankshaft, the cam lobe acts on the intake valve to open the intake valve.
    Type: Grant
    Filed: February 23, 2022
    Date of Patent: October 18, 2022
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: Anthony Perkins, Riccardo Meldolesi, Clive Lacy, Dustin Kramer
  • Patent number: 11476012
    Abstract: The disclosure provide an apparatus for producing a nuclide by using a liquid target which can perform the nuclear reaction process and can discharge the radioactive gas such as Radon within the vial. As described above, an apparatus for producing a nuclide by using a liquid target according to the present disclosure can minimize quantitative loss of a reactant by performing the nuclear reaction process using a target of a liquefied state and reusing a liquefied target on which the nuclear reaction process has not been performed, and can improve safety by enabling the radioactive gas generated to be disposed.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: October 18, 2022
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Se Young Oh, Sang Moo Lim, Kyo Chul Lee, Joo Hyun Kang
  • Patent number: 11474093
    Abstract: The present invention relates to a method for screening protein-protein interaction inhibitors using a nanopore, a method for analyzing protein structures, a method for analyzing protein-protein interactions, and a kit therefor.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: October 18, 2022
    Assignees: Korea Research Institute of Bioscience and Biotechnology, Seoul National University R&DB Foundation
    Inventors: Seung Wook Chi, Ki Bum Kim, Dong Kyu Kwak, Mi Kyung Lee, Hong Sik Chae, Ji Hyang Ha
  • Patent number: 11475980
    Abstract: In at least one illustrative embodiment, a method may comprise selecting a first plurality of text strings that each represent a nucleotide sequence that was read by a massively parallel sequencing instrument, where the nucleotide sequences represented by the selected first plurality of text strings each correspond to a first target locus, comparing the selected first plurality of text strings to one another to determine an abundance count for each unique text string included in the selected first plurality of text strings, identifying a first number of unique text strings included in the selected first plurality of text strings as representing noise responses, and determining a method detection limit as a function of the abundance counts for the first number of unique text strings identified as representing noise responses.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: October 18, 2022
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Brian A. Young, Esley M. Heizer, Angela T. Minard-Smith, Nancy J. McMillan, Gokhan Yavas, Daniel M. Bornman
  • Patent number: 11473238
    Abstract: The invention relates to a water-repellent and lipophilic composite needle-punched nonwoven fabric and a preparation method thereof. The method comprises the following steps: blending a PET fiber and a polyolefin-based fiber in a mass ratio of 3:1-1:3, and performing needle punching to obtain a composite needle-punched nonwoven fabric; carrying out hot-drying treatment on the composite needle-punched nonwoven fabric at 110-160° C. for 40-90 min; and carrying out water-repellent finishing on the hot-dried fabric using 50-70 mL/L of an aqueous solution of a modified resin-based fluorine-free waterproofing agent, and drying to obtain the water-repellent and lipophilic composite needle-punched nonwoven fabric, wherein the water-repellent finishing is dip rolling, the air pressure is 1.8 kPa and the liquid carrying rate is 160-230%.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: October 18, 2022
    Assignees: NANTONG TEXTILE AND SILK INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, SOOCHOW UNIVERSITY
    Inventors: Huijing Zhao, Yingmei Zhang
  • Patent number: 11475248
    Abstract: Acquiring labeled data can be a significant bottleneck in the development of machine learning models that are accurate and efficient enough to enable safety-critical applications, such as automated driving. The process of labeling of driving logs can be automated. Unlabeled real-world driving logs, which include data captured by one or more vehicle sensors, can be automatically labeled to generate one or more labeled real-world driving logs. The automatic labeling can include analysis-by-synthesis on the unlabeled real-world driving logs to generate simulated driving logs, which can include reconstructed driving scenes or portions thereof. The automatic labeling can further include simulation-to-real automatic labeling on the simulated driving logs and the unlabeled real-world driving logs to generate one or more labeled real-world driving logs. The automatically labeled real-world driving logs can be stored in one or more data stores for subsequent training, validation, evaluation, and/or model management.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 18, 2022
    Assignee: Toyota Research Institute, Inc.
    Inventors: Adrien David Gaidon, James J. Kuffner, Jr., Sudeep Pillai
  • Patent number: 11475577
    Abstract: A motion prediction system for predicting the motion of a random animate subject. A first neural network is a markerless motion capture network, trained to receive video data of the subject and to process the video data to generate a time sequence of musculoskeletal motion capture data. A second neural network is a motion prediction network, trained to receive the musculoskeletal motion capture data and to process the data to generate a prediction of the subject's location based on position change in position of joints and/or muscles.
    Type: Grant
    Filed: November 1, 2020
    Date of Patent: October 18, 2022
    Assignee: Southwest Research Institute
    Inventors: Samuel E. Slocum, Omar D. Medjaouri, Edmond M. DuPont, Christopher I. Mentzer
  • Patent number: 11476433
    Abstract: Provided is a light emitting device including a lower electrode, an upper electrode disposed to face the lower electrode, a quantum dot light emitting layer between the lower electrode and the upper electrode, an electron transport layer between the lower electrode and the quantum dot light emitting layer, and a hole transport layer between the upper electrode and the quantum dot light emitting layer, wherein the quantum dot light emitting layer includes a quantum dot, and a first ligand on a surface of the quantum dot, and a second ligand on the surface of the quantum dot.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: October 18, 2022
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sukyung Choi, Hyunkoo Lee, Byoung-Hwa Kwon, Jaehyun Moon, Hyunsu Cho, Chan-mo Kang, Chunwon Byun, Jin Wook Shin, Nam Sung Cho
  • Patent number: 11472777
    Abstract: Provided herein piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction. Also provided methods of treatment of diseases associated with said processes, e.g. Alzheimer's and Parkinson's diseases.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: October 18, 2022
    Assignee: THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.
    Inventors: Varda Shoshan-Barmatz, Arie Lev Gruzman