Abstract: The present invention relates to a method for predicting the risk of having the CLAD in a subject by measuring the expression level of TCL1A in a biological sample obtained from said subject. Inventors have used a large-scale gene expression profiling of whole blood cells to identify early biomarkers of BOS. Microarray experiments performed from 80 patients (40 stable (STA) and 40 BOS) identified 47 genes differentially expressed between STA and BOS recipients. An independent set of patients (13 STA, 11 BOS) was then used for external validation by qPCR. T-cell leukemia/lymphoma protein 1A (TCL1A) gene was identified and validated as a predictive marker of BOS more than 6 months before diagnosis with area under curve of 0.77. Accordingly, the invention relates to a method for predicting the risk of having the chronic lung allograft dysfunction (CLAD) and to a method for preventing the risk of having CLAD by administering immunosuppressive drugs.

Abstract: A convolutional neural-network calculating apparatus including a bidirectional-output operation module and a data scheduler is provided. The bidirectional-output operation module includes a number of bidirectional-output operators, a number of row-output accumulators, and a number of column-output accumulators. Each bidirectional-output operator has a row-output port and a column-output port. The row-output accumulators are coupled to the row-output ports, and the column-output accumulators are coupled to the corresponding column-output ports. The data scheduler is configured to provide a number of values of an input data and a number of convolution values of the convolution kernels to the bidirectional-output operators. In a first operation mode, the bidirectional-output operators output operation results to the corresponding column-output accumulators through the column-output ports.

Abstract: A reference voltage generating circuit includes a bandgap reference (BGR) circuit configured to output an active reference voltage at a first node according to a sample signal; a first charging circuit configured to charge a first capacitor using the active reference voltage according to the sample signal; a second charging circuit configured to charge a second capacitor using the active reference voltage according to the sample signal; and a comparing circuit configured to compare a voltage difference between a charge voltage of the first capacitor and a charge voltage of the second capacitor with a threshold value, wherein the sample signal is a pulse signal generated using an output of the comparing circuit and the charge voltage of the first capacitor is provided as a low power reference voltage in a low power operation mode.

Abstract: A method of treating eyelid laxity in a subject comprising exposing a tarsal plate of an eye, and applying to at least part of the exposed tarsal plate a photosensitizer that initiates crosslinking in response to photo-activating radiation; and irradiating the exposed tarsal plate with photo-activating radiation to initiate crosslinking in the tarsal plate tissue.

Abstract: Provided is a pressure sensitive display device including a sensing substrate, a reaction substrate provided on the sensing substrate, and spacers provided between the sensing substrate and the reaction substrate to space the sensing substrate apart from the reaction substrate. Here, the sensing substrate includes a flexible substrate and a touch electrode provided on one surface of the flexible substrate, which faces the reaction substrate. The reaction substrate includes a transparent substrate, a transparent electrode provided on one surface of the transparent substrate, which faces the sensing substrate, and a light emitting layer disposed on the transparent electrode.

Abstract: A used battery is discharged for a short time from a first Open Circuit Voltage (OCV1) to a second OCV2 and the discharge current ?Q measured. OCV1 is input to a calibration curve model to obtain a first modeled State of Charge (SOC1) value, and OCV2 is input to the calibration curve model to obtain a second modeled SOC2 value. The State of Health (SOH) is calculated as ?Q/[Qnew×(SOC1?SOC2)], where Qnew is the battery capacity when new. The used battery is sorted for reuse or disposal based on the SOH value. The calibration curve model is obtained by Artificial Intelligence (AI) modeling of OCV, SOC datapoints from fully charging and discharging used batteries. Only OCV values within a target region having a low first derivative of SOC as a function of OCV are modeled, and OCV1 and OCV2 are within this target region.

Abstract: The disclosure discloses a method, apparatus and system for detecting multi-mode electromagnetic acoustic and magnetic flux leakage and a sensor. The method comprises: S102, receiving an operation instruction for detecting an object to be detected, the operation instruction is used for controlling a detection sensor to enter into any one or more of working modes as follows: magnetic flux leakage detection, ultrasonic bulk wave detection, ultrasonic guided wave detection and surface wave detection; S104, controlling the detection sensor to output a corresponding detection signal according to the operation instruction; and S106, detecting the object to be detected on the basis of the detection signal. The technical solution achieves a purpose of using one sensor to realize various detection modes, such as magnetic flux leakage and electromagnetic acoustic modes, reduces complexity and cost of a detection system, and improves detection efficiency.

Abstract: Provided herein are compounds and compositions useful in increasing PPAR? activity. The compounds and compositions provided herein are useful for the treatment of PPAR? related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).

Abstract: A method of producing actinium by using liquefied radium includes producing Ac-225 using Ra-226 of a liquefied state, moving the produced Ac-225 in a liquefied state after Ac-225 is produced, and separating Ac-225 and reusing Ra-226. As a result, a nuclear reaction process of Ac-225 may be performed and loss of Ra-226 may be minimized. Further, such a method may improve safety by including a radon collection unit which is capable of discharging and isolating radon produced from Ra-226, thereby preventing radiation exposure due to radon.

Abstract: A cell product for prevention and/or treatment of vascular disorders such as aortic aneurysm, comprising a SSEA-3-positive pluripotent stem cell derived from a mesenchymal tissue in a living body or a cultured mesenchymal cell (Muse cell).

Abstract: A mobile platform is provided for a guided soft target. The mobile platform includes a platform base, and a drive unit that is configured to move the platform base along a ground surface. A projector assembly is provided, configured for projecting light patterns for visual display on an exterior of the guided soft target. The projector assembly may include a hardened housing defining at least one opening for projecting the light patterns. In certain aspects, the projector assembly is coupled to an outer surface of the platform base. In other aspects, the projector assembly may be built into, or is retractable into, an interior the platform base. The projector assembly may include a control module that is configured to be remotely controllable.

Abstract: A bumper for a mobile platform of a guided test platform includes a first end, a second end residing opposite the first end, a first surface extending between the first and second ends, and a second surface extending between the first and second ends and residing opposite the first surface. The bumper defines a ramp structure extending between the bumper first end and the bumper second end. The ramp structure is structured to guide a wheel of a vehicle in a direction away from the first surface as the wheel moves along the second surface in a direction from the bumper first end toward the bumper second end.

Abstract: A three-phase expandable AC system based on battery reconfiguration and a control method thereof are provided. The system includes a reconfigurable battery array capable of connecting to a load or being tied to a grid, and having a plurality of battery array modules. The reconfigurable battery array may perform charging or discharging with respect to the load or the grid, and may perform one of operations including: generating a single-phase AC voltage corresponding respectively to outputs of the battery array modules; generating a three-phase AC voltage corresponding to three battery array modules selected from the plurality of battery array modules; and generating a plurality of three-phase AC voltages in parallel from the plurality of battery array modules, and merging the three-phase AC voltages in parallel to scale power.

Abstract: Compositions containing a nucleic acid nanostructure having a desired geometric shape and antigens bound to its surface are provided. The nanostructures can be, for example, in the form of a 6-helix bundle or icosahedron. The nanostructure design allows for control of the relative position and/or stoichiometry of the antigen bound to its surface. The antigens displayed on the nanostructure surface are arranged with the preferred number, spacing, and 3D organization to elicit a robust immune response. The displayed antigen can be an HIV immunogen such as eOD-GT6, eOD-GT8, or variants thereof. The compositions may thus be useful as immunogens, vaccines, immunostimulators, adjuvants, and the like. Methods of inducing immune responses, inducing protective immunity, inducing the production of neutralizing antibodies or inhibitory antibodies, inducing tolerance, and treating cancer, infectious or autoimmune diseases are also provided.

Abstract: An abnormal packet detection apparatus and method are provided. The abnormal packet detection apparatus stores a whitelist corresponding to a protocol port, wherein the whitelist includes at least one legal packet record. Each legal packet record includes a legal packet length, a legal source address, and a legal variation position set, and corresponds to a reference packet. The abnormal packet detection apparatus determines that a current packet length and a current source address of a to-be-analyzed packet are respectively the same as the legal packet length and the legal source address of a reference packet record among the at least one legal packet record, determines a current variation position of the to-be-analyzed packet by comparing the to-be-analyzed packet with the reference packet corresponding to the reference packet record, and generates a detection result by comparing the current variation position with the legal variation position set of the reference packet record.

Abstract: Accordingly, embodiment herein disclose a method for handling block chain operation in a block chain system. The method includes parallelizing, by the block chain system, a block creation along with a consensus mechanism. The block creation along with the consensus mechanism includes parallelly combining a pre-computed state of a succeeding block (at height “k” greater than the current block, where “k” is a positive integer parameter chosen by the system designer) with transactions in a current block to obtain state to be stored in a next succeeding block (at height “k+1” greater than the current block) along with running a consensus protocol to finalize transactions to include in an immediate next block (at height one greater than the current block). Further, the method includes handling, by the block chain system, the block chain operation based on parallelizing. The method can be used for scaling up computation in blockchains.

Abstract: Disclosed herein include systems, methods, compositions, and kits for in situ readout of barcodes, such as DNA barcodes. Barcode constructs containing a promoter (e.g., a phage promoter) that is inactive in live cells can be integrated in the genomes of cells. Cells can be fixed, and phage RNA polymerase can be used for transcription of the barcode to RNA transcripts. The RNA transcripts can be detected using, for example, fluorescent imaging and used to determine barcode sequences.

Abstract: A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.

Abstract: Disclosed herein are a decoding method and apparatus and an encoding method and apparatus that perform inter-prediction using a motion vector predictor. For a candidate block in a col picture, a scaled motion vector is generated based on a motion vector of the candidate block. When the scaled motion vector indicates a target block, a motion vector predictor of the target block is generated based on the motion vector of the candidate block. The motion vector predictor is used to derive the motion vector of the target block in a specific inter-prediction mode such as a merge mode and an AMVP mode.

Abstract: The present disclosure is directed toward a measurement system capable of rapid spectroscopic and calorimetric analysis of the chemical makeup of a test sample. Systems in accordance with the present disclosure include a low-thermal-mass sample holder having a substrate whose surface has been engineered to create a large-area sample-collection surface. The sample holder includes an integrated temperature controller that can rapidly heat or cool the test sample. As a result, the sample holder enables differential scanning calorimetry Fourier-Transform Infrared Spectroscopy (DSC-FTIR) that can be performed in minutes rather than hours, as required in the prior art.