Abstract: A distance measuring apparatus includes an image sensor and an image sensor driver. The image sensor includes a photodiode, a first capacitor and a second capacitor, and a first transfer gate and a second transfer gate configured to transmit an output of the photodiode to the respective first and second capacitors. The image sensor driver is configured to complementarily drive the first transfer gate and the second transfer gate.

Abstract: According to some embodiments, a method can identify and discriminate contributions from one or more noise sources using the multi-level structure of a quantum system with three or more levels. The method can include: preparing the quantum system in a predetermined state; applying one or more control signals to the quantum system; measuring values of one or more observables of the quantum system that quantify the quantum system's response to the noise sources and the one or more applied control signals; extracting noise spectra information associated with the noise sources from the measured values; and identifying contributions from the one or more noise sources based on the noise spectra information.

Abstract: Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.

Abstract: The present invention is based on the identification of novel biomarkers predictive of responsiveness to anti-immune checkpoint therapies.

Abstract: The present disclosure generally relates to the field of resistive sensing. In particular, the present disclosure relates to a highly sensitive reduced graphene oxide-nickel (RGO—Ni) composite based fast response temperature sensor. Aspects of the present disclosure provide a method for fabrication of a highly sensitive reduced graphene oxide-nickel (RGO—Ni) composite-based temperature sensor. An aspect of the present disclosure provides a temperature sensor comprising: a substrate; and a composite film deposited onto said substrate, wherein the composite film comprises a reduced graphene oxide-nickel composite film. In an embodiment, the temperature sensor is cryo-compatible.

Abstract: Disclosed herein is a nano membrane. The nano membrane includes an insulating layer having a thickness corresponding to a diameter of each of metal nanowires and configured to contain the metal nanowires therein, and the metal nanowires arranged to cross and having portions of side surfaces which protrude from one surface of the insulating layer.

Abstract: The present disclosure provides a method for making a single photon detector with a modified superconducting nanowire. The method includes: preparing a substrate; modifying a superconducting nanowire with stress on a surface of the substrate; and fabricating a superconducting nanowire single photon detector based on the superconducting nanowire with stress. Based on the above technical solution, in the superconducting nanowire single photon detector provided by the present disclosure, the device material layer film has a certain thickness, the critical temperature of the device material can be reduced, the uniformity of the device material and small superconducting transition width are ensured, thereby improving the detection efficiency of the device.

Abstract: Provided herein are analogs of the natural product icariin represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The analogs can be used to modulate (e.g., inhibit, such as by competitive inhibition) PDE5 and thereby treat a wide range of PDE5-mediated diseases, including cardiovascular, gastrointestinal, pulmonary, musculoskeletal, neurological and reproductive diseases. Also provided herein are compositions and methods including compounds of Structural Formula (I).

Abstract: A semiconductor device includes a cell array, a computation circuit, and a control circuit. The cell array includes a plurality of unit cells configured to store a plurality of first signals by a write operation and to output a plurality of output signals corresponding to the first signals by a read operation. The computation circuit includes a plurality of unit computation circuits receiving the plurality of output signals and being set according to a plurality of second signals during a computation operation. The control circuit is configured to control the cell array and the computation circuit during the write operation, the read operation, and the computation operation.

Abstract: Systems and methods in accordance with embodiments of the invention impalement adaptive electric vehicle (EV) charging. One embodiment includes one or more electric vehicle supply equipment (EVSE); an adaptive EV charging platform, including a processor; a memory containing: an adaptive EV charging application; a plurality of EV charging parameters. In addition, the processor is configured by the adaptive EV charging application to: collect the plurality of EV charging parameters from one or more EVSEs, simulate EV charging control routines and push out updated EV charging control routines to the one or more EVSEs. Additionally, the adaptive EV charging platform is configured to control charging of EVs based upon the plurality of EV charging parameters collected from at least one EVSE.

Abstract: Methods are provided for reducing blood glucose, which utilize an agent that increases the biological activity of a vitamin D receptor (VDR) (e.g., a VDR agonist), in combination with an antagonist of bromodomain-containing protein 9 (BRD9). IN some examples, such methods treat type II diabetes.

Abstract: The present invention is based on the identification of novel biomarkers predictive of responsiveness to anti-immune checkpoint therapies.

Abstract: In order to provide a means to uniquely estimate the attitude in a wider range of angles to thereby realize a more accurate attitude estimate, a planar marker is provided. The planar marker includes a planar visual marker having a two-dimensional pattern code and at least two attitude inversion detection patterns Fx and Fy each consisting of a transparent cylindrical body having a pattern on the side face within the range of 180 degrees around the central axis ra and being provided so as to be orthogonal to each other on the same plane as that of planar visual marker. A marker is provided that includes at least one attitude inversion detection pattern. The attitude inversion detection pattern consists of the planar visual marker and a transparent spherical body having a pattern on a hemispherical surface and is provided on the same plane as that of the planar visual marker.

Abstract: Disclosed is an image decoding method using the correlation between color components to perform into prediction of chrominance components. Here, the image decoding method using the correlation between color components to perform intra prediction of chrominance components comprises the steps of: checking image data and a prediction mode in a bitstream; generating a prediction block according to a reconstructed prediction mode; determining compensation settings according to the size of a current block and the reconstructed prediction mode; compensating the prediction block according to the determined compensation settings; and reconstructing the current block by adding reconstructed image data to the prediction block.

Abstract: In a phosphor according to an aspect, an emission site has a perovskite crystal structure expressed by ABX3, in which A and B are each a cation and X is an anion, and an emission element is located at a B site serving as a body center of the perovskite crystal structure.

Abstract: Compositions and methods for the treatment of ocular diseases are disclosed. In accordance with one aspect of the instant invention, methods for treating, inhibiting (e.g., reducing), and/or preventing an ocular disease in a subject are provided. The methods comprise the administration of at least one inhibitor of the induction or activity of tryptophan degradation and/or of the downstream pathways that respond to this process. In a particular embodiment, the methods comprise the administration of an inhibitor of IDO1.

Abstract: A microscale photoacoustic sensor uses the detection of ultrasound waves generated by a sample in response to incident light absorption to perform photoacoustic spectroscopy, imaging, and microscopy. The microscale photoacoustic sensor, including components to excite a sample and detect ultrasound waves, may be integrated onto a single chip. The microscale photoacoustic sensor may excite a sample using a metasurface collimator. The metasurface collimator includes an array of diffraction grooves to collimate an excitation beam uniformly out of the plane of the sensor to create a wide and homogeneous beam spot. The microscale photoacoustic sensor may detect ultrasound waves using an optical photoacoustic transducer. The optical photoacoustic transducer includes a resonator on a mechanical membrane to detect ultrasound waves with high sensitivity. The microscale photoacoustic sensor may be used in applications such as deep-tissue neural imaging or microfluidic biological screening.

Abstract: Deployable reflectors and antennas and spacecraft using such reflectors are disclosed. An example disclosed reflector includes: a hub having a cross-section formed in a circular, elliptical or polygonal shape; a plurality of ribs, each rib having an inner side surface facing an outer peripheral side of the hub when folded, and an outer side surface that is a surface opposite to the inner side surface, the plurality of ribs being folded to be wound around an outer periphery of the hub such that the inner side surface of each rib and the outer side surface of its adjacent rib partially face each other or the outer side surface of each rib and the inner side surface of its adjacent rib partially face each other, each rib being deployed in a parabolic shape; and a sheet installed across each of the plurality of ribs and capable of reflecting radio waves.

Abstract: A base station of a wireless communication system is disclosed. The base station of the wireless communication includes a communication module, and a processor. The processor generates a preemption indicator indicating a preempted resource. In this case, the resource indicated by the preemption indicator does not include an orthogonal frequency divisional multiplexing (OFDM) symbol configured as an uplink (UL) symbol by a radio resource control (RRC) signal. The processor is configured to transmit the preemption indicator to a user equipment of the wireless system based on a predetermined period.

Abstract: Provided herein are dibenzocyclooctyne compounds useful as reagents in 1,3-dipolar cycloaddition reactions, and methods for their preparation.