Patents Assigned to INSTITUTE
  • Publication number: 20220152187
    Abstract: The present invention provides a recombinant Vaccinia virus as a dengue virus vaccine that can be used as a therapeutic or prophylactic agent in the clinic. This recombinant Vaccinia virus is characterized by including: all or part of a cDNA that encodes a non-structural protein from a dengue virus; and an expression promoter.
    Type: Application
    Filed: March 13, 2020
    Publication date: May 19, 2022
    Applicants: TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, KAGOSHIMA UNIVERSITY, NAGASAKI UNIVERSITY
    Inventors: Michinori KOHARA, Fumihiko YASUI, Daisuke YAMANE, Kyoko KOHARA, Kouichi MORITA, Yasuhiro YASUTOMI, Koji ISHII
  • Publication number: 20220154250
    Abstract: The present disclosure relates to a composition for discriminating the species Lactobacillus acidophilus, which enables microorganisms belonging to the species Lactobacillus acidophilus to be discriminated, detected and identified simply, quickly and accurately from a target sample. Therefore, the present disclosure can be effectively used in the development of fermented milk, baby food, dairy products, livestock feed, cosmetics, health supplements, drugs for intestinal disorders, raw materials, etc. using the Lactobacillus acidophilus sp. strain.
    Type: Application
    Filed: May 29, 2019
    Publication date: May 19, 2022
    Applicant: KOREA FOOD RESEARCH INSTITUTE
    Inventors: Young-do NAM, Won-Hyong CHUNG, Mi Young LIM, So-Young LEE, Yong-Soo PARK, Jisu KANG, Yun-Tai KIM, Hee Soon SHIN, Ji-hee SHIN, Seungpyo Hong
  • Publication number: 20220156536
    Abstract: The system includes a metric map creation unit configured to create a metric map using first image data received from a 3D sensor, an image processing unit configured to recognize an object by creating and classifying a point cloud using second image data received from an RGB camera; a probability-based map production unit configured to create an object location map and a spatial semantic map in a probabilistic expression method using a processing result of the image processing unit, a question creation unit configured to extract a portion of high uncertainty about an object class from a produced map on the basis of entropy and ask a user about the portion, and a map update unit configured to receive a response from the user and update a probability distribution for spatial information according to a change in probability distribution for classification of the object.
    Type: Application
    Filed: August 24, 2021
    Publication date: May 19, 2022
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Yoon Seon OH, Ho Yeon HWANG, Sung Kee PARK, Chang Joo NAM
  • Publication number: 20220153258
    Abstract: Aspects of the disclosure provide a parking method and system for a vehicle. For example, the parking system can include a processor and an output circuit. As another example, the parking system can include the processor and a compelling unit. The processor can be configured to determine whether a first weather condition, such as snowing, raining, icing and hailing, at a first parking location meets a first criterion, and identify, when the first weather condition meets the first criterion, a second parking location at which a second weather condition meets a second criterion different from the first criterion. The output unit can be configured to output an alert to the vehicle parked at the first parking location indicating that the vehicle is to be moved to the second parking location. The compelling unit can be configured to compel the vehicle to move to the second parking location.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 19, 2022
    Applicant: TOYOTA RESEARCH INSTITUTE, INC.
    Inventors: Nikos ARECHIGA-GONZALEZ, Soonho KONG, Jonathan DECASTRO, Frank PERMENTER, Dennis PARK
  • Publication number: 20220152109
    Abstract: The application provides genetically modified cell receptors (TCRs) specific for an epitope from cancer antigen NY-ESO-1. Also provided are related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells, including but not limited to genetically engineered cells, and pharmaceutical compositions. The application further provides the use of such modified T cell receptors (TCRs) and related compositions for cancer immunotherapy (e.g., adoptive cell therapy).
    Type: Application
    Filed: March 17, 2020
    Publication date: May 19, 2022
    Applicant: LUDWIG INSTITUTE FOR CANCER RESEARCH LTD
    Inventors: George COUKOS, Melita IRVING, Vincent ZOETE, Olivier MICHIELIN
  • Publication number: 20220157661
    Abstract: Embodiments including apparatus, systems, and methods for nanofabrication are provided. In one example, a method of manufacturing a semiconductor device includes forming a two-dimensional (2D) layer comprising a 2D material on a first substrate and forming a plurality of holes in the 2D layer to create a patterned 2D layer. The method also includes forming a single-crystalline film on the patterned 2D layer and transferring the single-crystalline film onto a second substrate.
    Type: Application
    Filed: November 19, 2021
    Publication date: May 19, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Jeehwan Kim, Sanghoon Bae, Yunjo Kim
  • Patent number: 11336622
    Abstract: An apparatus for deploying a firewall on a software-defined network (SDN) includes a public key distributor configured to transmit a public key, a resource monitor configured to monitor resources of a network, a host monitor configured to receive a firewall rule of at least one host, which is encrypted by the public key, a decryption unit configured to decrypt information received from the host monitor by using a secret key, a merge unit configured to merge the decrypted information to provide a merged firewall rule, and a firewall deployment unit configured to deploy the merged firewall rule to a switch.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: May 17, 2022
    Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyuk Lim, Sung Hwan Kim, Jargalsaikhan Narantuya, Seung Hyun Yoon
  • Patent number: 11333663
    Abstract: A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: May 17, 2022
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Timothy Manning Swager, Joseph Michael Azzarelli, Shinsuke Ishihara
  • Patent number: 11332372
    Abstract: The present disclosure provides an apparatus capable of continuously producing carbon nanotubes having high crystallinity, a low residual catalyst content and a high aspect ratio. The apparatus for producing carbon nanotubes includes: a reaction unit configured to synthesize carbon nanotubes (CNTs), a supply unit configured to supply a carbon source to the reaction unit through a supply pipe; and a collection unit configured to collect carbon nanotubes discharged from the reaction unit, wherein the reaction unit may include a chemical vapor deposition reactor.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: May 17, 2022
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Seung Min Kim, Sung Hyun Lee, Jun Beom Park, Ji Hong Park, Dong Myeong Lee, Sook Young Moon, Hyeon Su Jeong
  • Patent number: 11333634
    Abstract: A signal sensing module includes a substrate, a sensing electrode, a piezoresistive material layer and a sensing circuit. The substrate has a surface. The sensing electrode is disposed on the substrate and is exposed from the surface. The piezoresistive material layer is formed on the surface and covers the sensing electrode. The piezoresistive material layer has a resistance value. The sensing circuit is disposed in the substrate and adapted to sense a change of resistance value when a pressure wave passes through the piezoresistive material layer.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: May 17, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventor: Kuo-Tso Chen
  • Patent number: 11335018
    Abstract: The present application provides a volumetric measuring method and apparatus based on a TOF depth camera, which is achieved by: acquiring depth images; denoising the depth images; selecting a first feature area of the first depth image and a second feature area of the second depth image that have been denoised respectively, traversing each pixel point in the first feature area at multiple traversal speeds, and matching a first depth value of a current pixel point with a second depth value of a target pixel point corresponding to the current pixel point in the second feature area to acquire multiple total similarity values; determining a traversal speed corresponding to a maximum total similarity value as an instantaneous speed at a current moment; calculating a package volume according to the instantaneous speed. The present application effectively solves the problem that an accurate package volume cannot be obtained when a speed of the conveyor belt is not fixed, and high in feasibility.
    Type: Grant
    Filed: January 7, 2022
    Date of Patent: May 17, 2022
    Assignee: WEIHAI INNOVATION INSTITUTE, QINGDAO UNIVERSITY
    Inventors: Weizhong Zhang, Zenghui Liu, Chi Zhang, Hongfeng Zhang, Cuimei Yuan, Yongpan Li, Tianyu Chen
  • Patent number: 11331856
    Abstract: The present application relates to a linear light source using ultraviolet light emitting diodes (LEDs), and a photopolymer 3D printer comprising the linear light source. The linear light source may include a substrate distanced from a polymer case of the photopolymer 3D printer and an ultraviolet LED array in which a plurality of ultraviolet LEDs, which project ultraviolet rays toward the polymer case, are arranged on the substrate in multiple rows in the X-axis direction. The arrangement of the multiple columns in the Y-axis direction is at an oblique angle to the multiple rows.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: May 17, 2022
    Assignee: Korea Electronics Technology Institute
    Inventors: Jaehyoun Park, Yonggon Seo, Jinkoog Shin
  • Patent number: 11332719
    Abstract: The present invention generally relates to methods and compositions used delivery of gene editing compositions including transcriptional effectors with parvovirus and preferred methods for making same.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 17, 2022
    Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Feng Zhang, Mark D. Brigham, Le Cong, Silvana Konermann
  • Patent number: 11331791
    Abstract: A 3 DOFs decoupling spherical parallel mechanism provided by the present disclosure comprises: a fixed platform, a rotation assembly, a moving platform, a first arc kinematic chain, a second arc kinematic chain, a first arc rod, and a second arc rod. In the 3 DOFs decoupling spherical parallel mechanism, the rotation assembly can drive the moving platform to rotate by 360 degrees around a direction being perpendicular to the fixed platform, and the first arc rod and the second arc rod reciprocate along tangential directions of the first arc kinematic chain and of the second arc kinematic chain respectively to enable the moving platform to rotate around an axis of a plane where the first arc kinematic chain or the second arc kinematic chain is located. In this way, the rotations of the moving platform in three directions are respectively driven by driving units in three directions and being independent from each other, such that the three rotation actions of the mechanism have decoupling capability.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: May 17, 2022
    Assignee: SHENZHEN INSTITUTE OF ADVANCED TECHNOLOGY
    Inventors: Guoru Zhao, Yongfeng Wang
  • Patent number: 11336250
    Abstract: A method for preparing a film bulk acoustic wave device by using a film transfer technology includes: 1) providing an oxide monocrystal substrate; 2) implanting ions from the implantation surface into the oxide monocrystal substrate, and then forming a lower electrode on the implantation surface; or vice versa; and forming a defect layer at the preset depth; 3) providing a support substrate and bonding a structure obtained in step 2) with the support substrate; 4) removing part of the oxide monocrystal substrate along the defect layer so as to obtain an oxide monocrystal film, and transferring the obtained oxide monocrystal film and the lower electrode to the support substrate; 5) etching the support substrate from a bottom of the support substrate to form a cavity; 6) forming an upper electrode on the surface of the oxide monocrystal film.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: May 17, 2022
    Assignee: SHANGHAI INSTITUTE OF MICROSYSTEM AND INFORMATION TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Xin Ou, Kai Huang, Qi Jia, Shibin Zhang, Tiangui You, Xi Wang
  • Patent number: 11333661
    Abstract: A detection analyzer including a first sample input/output element, a second sample input/output element, a sample compartment, a vibration platform, a vibration generator, a data acquisition system, a laser converter, and a data display. The first sample input/output element and the second sample input/output element are each connected to the sample compartment; the vibration platform is located inside the sample compartment; the vibration generator is located outside the sample compartment, and the vibration platform is connected to the vibration generator; the data acquisition system is located outside the sample compartment, and is connected to the vibration platform; and the data display is connected to the data acquisition system.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: May 17, 2022
    Assignees: CIXI INSTITUTE OF BIOMEDICAL ENGINEERING NINGBO INSTITUTE OF INDUSTRIAL TECHNOLOGY, CHINESE ACADEMY OF SCIENCES, NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Fang Yang, Aiguo Wu
  • Patent number: 11331203
    Abstract: A multi-component implant insertion system for insertion of an intervertebral implant cage and methods of use thereof are described herein. Preferably, the proximal end of a hollow jaw is inserted into the distal end of an inserter. Once inside the inserter, a thread on the jaw engages a corresponding thread inside the inserter, allowing axial advancement of the jaw along the inserter. A ram is inserted through the proximal end of the jaw until the distal end of the ram protrudes at the distal end of the inserter assembly. Optionally, an adjustable stop introduced onto the superior portion of the inserter allows for control over the depth of insertion of the implant. An implant of appropriate size is introduced to the jaw of the inserter assembly and the implant/inserter assembly can be impacted into the vertebral body until the adjustable stop contacts the anterior edge of the vertebral body.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: May 17, 2022
    Assignee: Institute For Musculoskeletal Science and Education, Ltd.
    Inventors: William Duffield, James A. Sack
  • Patent number: 11331383
    Abstract: The present invention provides an attenuated African Swine Fever (ASF) virus which lacks a functional version of the following genes: multigene-family 360 genes 9L, 10L, 11L, 12L, 13L and 14L; and multigene-family 505 genes 1R, 2R, 3R and 4R. The invention further provides an attenuated African Swine Fever (ASF) virus which Lacks a functional version of the DP148R gene. The present invention also provides a vaccine comprising such an attenuated virus and its use to prevent ASF. Further, the invention relates to intranasal administration of an attenuated ASF virus.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: May 17, 2022
    Assignee: THE PIRBRIGHT INSTITUTE
    Inventors: Charles Abrams, Ana-Luisa Reis, Chris Netherton, Linda Dixon, Dave Chapman, Pedro Sanchez-Cordon
  • Patent number: 11332729
    Abstract: This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 17, 2022
    Assignee: California Institute of Technology
    Inventors: David K. Romney, Javier Murciano Calles, Jori E. Wehrmuller
  • Patent number: 11332747
    Abstract: Bispecific aptamers having a first end that specifically binds to a first tumor specific marker, tumor antigen, or viral protein and a second end that specifically binds to a second tumor specific marker, tumor antigen, or viral protein are provide. The bispecific aptamers can be used to treat cancer or virally infected cells. Generally, the bispecific aptamers bind to two surface proteins, preferably different proteins, on the same cell. In a preferred embodiment the bispecific aptamers bind to two different tumor markers, tumor antigens, tumor specific proteins and combinations thereof.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: May 17, 2022
    Assignee: AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.
    Inventor: Hongyan Liu