Patents Assigned to InterVet, Inc.
  • Publication number: 20210030862
    Abstract: The present invention pertains to a vaccine comprising an IgM protease antigen of Streptococcus suis, for use in a method for protecting pigs against an infection with Streptococcus suis of serotype 2 and against an infection with Streptococcus suis of serotype 9.
    Type: Application
    Filed: December 14, 2018
    Publication date: February 4, 2021
    Applicant: Intervet Inc.
    Inventor: Antonius Arnoldus Christiaan Jacobs
  • Publication number: 20210023303
    Abstract: A device for administering a fluid is provided, with a cylinder (16, 116) which has an open dispensing end (17), a piston (36) which is displaceable between a front and rear end position in the cylinder (16, 116) and is connected to a piston rod (35) that protrudes along a first direction beyond a rear end of the cylinder (16, 116) opposite the open dispensing end (17) and is guided in a receiving block (10), a nonreturn valve (18) closing the open dispensing end (17), and a tensioning device (S) which is connected to the piston rod (35, 135) and is arranged in the receiving block (10).
    Type: Application
    Filed: March 26, 2019
    Publication date: January 28, 2021
    Applicant: Intervet Inc.
    Inventors: Frank Altermann, Dominic Kamenzin, Manuel Mattes, Robin Sauter, Thomas Schmidt, Daniel Seeh
  • Publication number: 20200405692
    Abstract: The present invention relates to methods of treating demodicosis by administering an isoxazoline compound of formula (I)
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Applicant: Intervet Inc.
    Inventors: Heike Williams, Anja Regina Heckeroth, Janina Tanzler, Regis Joel Alain Frenais
  • Patent number: 10875847
    Abstract: The instant invention provides compounds of formula I which are selective JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as atopic dermatitis, arthritis, and cancer.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: December 29, 2020
    Assignee: Intervet Inc.
    Inventors: Peter H. Fuller, Jason Brubaker, Jonathan R. Young
  • Publication number: 20200390748
    Abstract: Liquid veterinary pour-on or spot-on composition comprising at least one isoxazoline compound of formula (I) and a pharmaceutically acceptable carrier comprising at least one dermal penetration 5 enhancer comprising menthol and a solvent system comprising a pyrrolidone solvent are disclosed. Methods for using and administering such preparation in the prevention and control of parasite infestations in livestock animals are also disclosed.
    Type: Application
    Filed: December 21, 2018
    Publication date: December 17, 2020
    Applicant: Intervet Inc.
    Inventors: John Gerard SHEEHAN, Keith FREEHAUF, Annie FLOCHLAY-SIGOGNAULT
  • Publication number: 20200390712
    Abstract: The present invention pertains to a method for producing a medicinal product comprising a biologically active protein comprising the steps of providing an aqueous composition comprising a solvent, the biologically active protein and between 20% w/w and 60% w/w of a non-polymeric sugar, freezing the composition, thereby forming at least one frozen body comprising the solvent in frozen form, putting the frozen body in a drying apparatus while being carried by a support, the support comprising one or more restraining elements that define one or more boundaries of the support, wherein at most 30% of the surface of the body is contiguous with the one or more restraining elements, reducing the pressure in the drying apparatus below atmospheric pressure, providing heat to the body in order to sublimate the frozen solvent of the body and obtain a dried body. The invention also pertains to a product obtainable by this method.
    Type: Application
    Filed: July 1, 2020
    Publication date: December 17, 2020
    Applicant: Intervet Inc.
    Inventors: Kevin O'Connell, Sandhya Buchanan
  • Patent number: 10863727
    Abstract: The present invention pertains to a method for automatic sea lice monitoring in fish aquaculture, the method comprising submerging a camera (4) in a sea pen (300) comprising fish, using the camera to make an image of at least one of said fish, analysing the image to differentiate between individual sea lice present on the fish and the fish itself and assessing the number of sea lice present on the fish, wherein the camera is attached to a device (1, 10, 100) for guiding the salmon along an imaging track (5), the camera being directed to the track.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: December 15, 2020
    Assignee: Intervet Inc.
    Inventors: Peter Jans, Evert Gijtenbeek
  • Patent number: 10864195
    Abstract: This invention provides topical localized formulations comprising an isoxazoline compound and a pharmaceutically or veterinary acceptable liquid carrier vehicle comprising N,N-diethyl-3-methylbenzamide as a solvent and an improved method for controlling, and preventing parasite infestation in animals.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: December 15, 2020
    Assignee: Intervet Inc.
    Inventors: Stefan Fuchs, Anja Regina Heckeroth, Ramona Müller, Heike Williams, Hartmut Zoller
  • Publication number: 20200384102
    Abstract: The invention pertains to a vaccine comprising in combination non-replicating immunogens of Erysipelothrix rhusiopathiae, porcine parvo virus, Leptospira interrogans and live attenuated PRRS virus, and a pharmaceutically acceptable carrier, for use in a method for prophylactic treatment of a swine against an infection with Erysipelothrix rhusiopathiae, porcine parvo virus, Leptospira interrogans and PRRS virus, wherein the vaccine is administered in a single dose with regard to the treatment against an infection with PRRS virus.
    Type: Application
    Filed: November 28, 2017
    Publication date: December 10, 2020
    Applicant: Intervet Inc.
    Inventors: Erwin Born van den, Antonius Arnoldus Christiaan Jacobs, Melanie Sno
  • Patent number: 10858437
    Abstract: The present invention discloses antibodies and blocking antibodies to canine IL-4 receptor alpha that have specific sequences and a high binding affinity for canine IL-4 receptor ?. The present invention also discloses the use of the antibodies of the present invention in the treatment of atopic dermatitis in dogs. The present invention further discloses unique epitopes that bind to the antibodies to canine IL-4 receptor alpha.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: December 8, 2020
    Assignee: Intervet, Inc.
    Inventors: Mohamad Morsey, Yuanzheng Zhang
  • Patent number: 10852286
    Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: December 1, 2020
    Assignee: Intervet, Inc.
    Inventors: Michelle Allen, Mark Garrett, Urs Peter Bruderer, Martinus Antonius Johannes Thijssen
  • Publication number: 20200368346
    Abstract: The present invention describes a liquid vaccine composition of a live enveloped virus and a pharmaceutically acceptable carrier, whereby the carrier is a natural deep-eutectic solvent (NADES), and the vaccine has a water activity of less than about 0.8. The NADES provides a stabilisation of the sensitive virus for prolonged time and at ambient temperature. In general, the liquid vaccine compositions according to the invention, in different compositions for the various enveloped viruses, show remarkable capabilities of stabilisation. This overcomes the need for lyophilisation, a great economic benefit. Also the liquid nature of the vaccines facilitates administration to human or animal targets.
    Type: Application
    Filed: December 21, 2018
    Publication date: November 26, 2020
    Applicant: Intervet Inc.
    Inventors: Paul Vermeij, Edwin Kets, Chris Dirks, Martin Piest
  • Publication number: 20200367475
    Abstract: A method for external fish parasite monitoring in aquaculture, comprising the steps of: —submerging a camera (52) in a sea pen containing fish, the camera having a field of view; —capturing images of the fish with the camera (52); and—identifying external fish parasite on the fish by analyzing the captured images, characterized in that a target region within the field of view of the camera (52) is illuminated from above and below with light of different intensities and/or spectral compositions.
    Type: Application
    Filed: December 19, 2018
    Publication date: November 26, 2020
    Applicant: Intervet Inc.
    Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
  • Publication number: 20200354450
    Abstract: The present invention discloses antibodies to canine PD-1 that have specific sequences and a high binding affinity for canine PD-1. The invention also discloses the use of the antibodies of the present invention in the treatment of cancer in dogs.
    Type: Application
    Filed: June 5, 2020
    Publication date: November 12, 2020
    Applicant: Intervet Inc.
    Inventors: Mohamad Morsey, Yuanzheng Zhang, Denise Bartels-Morozov, Jason Erskine, Ian Tarpey
  • Publication number: 20200345832
    Abstract: The present invention provides a vaccine for rabies virus and methods of making and using the vaccine alone, or in combinations with other protective agents.
    Type: Application
    Filed: November 5, 2018
    Publication date: November 5, 2020
    Applicant: Intervet Inc.
    Inventor: Ian Tarpey
  • Publication number: 20200338186
    Abstract: The present invention provides new feline calicivirus vaccines, including multivalent vaccines. The present invention also provides methods of making and using the vaccines.
    Type: Application
    Filed: November 5, 2018
    Publication date: October 29, 2020
    Applicant: Intervet Inc.
    Inventor: Ian Tarpey
  • Publication number: 20200337274
    Abstract: A system for external fish parasites monitoring in aquaculture, the system comprising: a camera (52) suitable to be submerged in a sea pen suitable for containing comprising fish, the camera being arranged for capturing images of the fish; and an electronic image processing system (86) configured for identifying external fish parasites on the fish by analyzing the captured images, wherein: a ranging detector (54) configured for detecting the presence of fish and measuring a distance from the detector to the fish is mounted adjacent to the camera (52); and an electronic control system (12) is arranged to control a focus of the camera (52) on the basis of the measured distance and to trigger the camera (52) when a fish has been detected within a predetermined distance range.
    Type: Application
    Filed: December 19, 2018
    Publication date: October 29, 2020
    Applicant: Intervet Inc.
    Inventors: Russel Howe, Zachary Lizer, James Wallace Sarrett, Peter Jon Abrahamson, Jascha Tucker Little
  • Patent number: 10813586
    Abstract: A system and method are provided for diagnosis of animal respiratory diseases using auscultation techniques. Animal lung sounds are recorded and stored as digitized data. Algorithms are applied to the data producing an output indicative of the health of the animal. Another method determines effectiveness of antibiotics administered to animals based upon observed relationships between lung score categories obtained from auscultation. A comparison is made between sample populations of animals that receive different classifications of antibiotics, and this data is compared to lung score categories observed for each of the animals that received the antibiotics. A statistical analysis is conducted to confirm statistical differences in case fatality rates between lung score categories.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: October 27, 2020
    Assignee: INTERVET INC.
    Inventors: Kurt Brattain, Randolph K. Geissler
  • Publication number: 20200330585
    Abstract: The present invention provides vectors and/or nucleic acid constructs that encode one or more influenza A virus neuraminidase (NA) antigens. The present invention also provides vaccine against influenza A virus comprising such vectors and/or nucleic acid constructs. The present invention further provides methods of making and using the vaccines alone, or in combination with other protective agents.
    Type: Application
    Filed: December 17, 2018
    Publication date: October 22, 2020
    Applicant: Intervet Inc.
    Inventors: Mark A. Mogler, Pravina Kitikoon, Supraja Puttamreddy, Erin Strait, Ruud Philip Antton Maria SEGERS, Basav Nagaraj
  • Publication number: 20200331867
    Abstract: The application relates to a process to produce large isoxazoline compound particles which comprises initiating crystallization and then maintaining the temperature of the crystallization in the metastable region by removing, reheating and recycling a portion of the solvent thereby allowing the existing crystals to grow larger while minimizing the formation of newer smaller crystals.
    Type: Application
    Filed: November 6, 2018
    Publication date: October 22, 2020
    Applicant: Intervet Inc.
    Inventors: Luke Ryan Schenck, Athanas Koynov, George X. Zhou, Aaron Cote