Abstract: The present invention relates to efflux inhibitor compositions and methods of using these agents for treating conditions where the activity of efflux transporter proteins (e.g., Breast Cancer Resistance Protein (BCRP) and P-Glycoprotein (P-GP)) inhibit effective delivery of a therapeutic agent to a target tissue (e.g., brain, spinal cord, nerves, cerebrospinal fluid, testis, eyeballs, retina, inner ear, placenta, mammary gland, liver, biliary tract, kidney, intestines, lung, adrenal cortex, endometrium, hematopoietic cells, and/or stem cells).

Abstract: A method for producing an antimicrobial agent is provided. The method includes co-fermenting at least one seed of Lepidium Sativum and at least one yeast in a growth media to produce a yeast lees co-fermented by-product. The yeast lees by-product is then applied to a growth medium and at least one cell of Ganoderma Lucidum as a liquid medium under controlled conditions to produce mycelium and the liquid medium is agitated. The liquid medium is then filtered to isolate and extract an antimicrobial agent.

Abstract: A vehicle system includes a floor. A dashboard is positioned vehicle-upward of the floor. A plurality of seating assemblies are coupled to the floor and are arranged into a first row and a second row. A base is coupled to the floor and comprises a trough that extends vehicle-rearward from a forward end to a rearward end. A storage console is coupled to the base and is operable to slide within the trough between a forward position that is proximate to the forward end, a rearward position that is proximate to the rearward end, and an intermediate position there between.

Abstract: This disclosure is generally directed to mitigating light-emitting diode (LED) imaging artifacts in an imaging system of a vehicle. In an example embodiment, the imaging system includes a first camera that operates under control of a first pulse trigger sequence, and a second camera that operates under control of a second pulse trigger sequence. The second pulse trigger sequence has a temporal offset with respect to the first pulse trigger sequence. The first camera captures an image of a light source, such as a traffic light containing LEDs. This image may contain an LED imaging artifact indicating that the traffic light is off. The second camera also captures an image of the light source. The temporal offset of the second pulse trigger sequence may eliminate the LED imaging artifact in the second image. A controller may compare the two images and determine that the traffic light is actually on.

Abstract: A motor vehicle includes a steering wheel and/or pedals that can be moved from an active driving position to an inactive or stowed position. The motor vehicle may include a pedal shield that substantially blocks a driver's access to the pedals when the pedals are in an inactive position. The steering wheel and pedals may shift laterally simultaneously between the active and inactive positions or configurations.

Abstract: The disclosure describes systems and methods including for monitoring and remotely controlling a fleet of autonomous vehicles. The remote vehicle control system determines a control input to control a vehicle based on an action performed on or with a controller bot. The controller bot is configured for use on a horizontal display that displays a map and a vehicle graphic at a location on the map.

Abstract: A process for preparing C2 to C5 paraffins includes introducing a feed stream comprising hydrogen gas and a carbon-containing gas into a reaction zone of a reactor, and converting the feed stream into a product stream comprising C2 to C5 paraffins in the reaction zone in the presence of a hybrid catalyst. The hybrid catalyst includes a metal oxide catalyst component and a microporous catalyst component. The metal oxide catalyst component satisfies: an atomic ratio of Cu/Zn from 0.01 to 3.00; an atomic ratio of Cr/Zn from 0.01 to 1.50; and percentage of (Al+Cr) from greater than 0.0 at % to 50.0 at % based on a total amount of metal in the metal oxide catalyst component.

Abstract: Additive manufacturing compositions include low-absorbing particles or non-absorbing particles that have an absorbance for wavelengths of 300 nm to 700 nm that is equal to or greater than 0 Au and is less 1.0 Au, such as 0.001 Au?absorbance?0.7 Au. Slurries including such particles and an uranium-containing particle and that are used in additive manufacturing processes have an increased penetration depth for curative radiation. Removal of low-absorbing particles or non-absorbing particles during post-processing of as-manufactured products results in pores that create porosity in the as-manufactured product that provide a volume accommodating fission gases and/or can enhance wicking of certain heat pipe coolant liquids.

Abstract: A vehicle having a heating and cooling system includes a refrigerant loop for conveying refrigerant, a coolant loop for conveying coolant, a chiller configured to convey the refrigerant and the coolant, and a vessel coupled to the chiller and having a phase change material disposed therein. The phase change material is configured to freeze via heat transfer from the phase change material to the refrigerant and melt via heat transfer from the coolant to the phase change material.

Abstract: A vehicle includes a vehicle frame having first frame rail and a second frame rail spaced from each other. The vehicle frame includes a cross-member extending from the first frame rail to the second frame rail. A battery enclosure extends from the first frame rail to the second frame rail. The battery enclosure includes a first side member and a second side member. The first side member is connected to and deformable relative to the first frame rail. The second side member is connected to and deformable relative to the second frame rail. The battery enclosure includes a reinforcement connected to the first side member, the second side member, and the cross-member.

Abstract: Systems and methods for predicting travel patterns of a vehicle or one or more occupants in the vehicle are provided. A transceiver may receive data indicative of at least one of passenger information, vehicle occupancy, vehicle status, and vehicle location from at least one of a voice recognition device, IoT sensors such as seat sensors, vehicle status sensors, or a GPS system. A processor may determine travel patterns based on the data, predict travel patterns based on the determined travel patterns, and generate a database comprising the predicted travel patterns. In addition, the processor may generate an alert if the determined travel pattern deviates from the predicted travel patterns.

Abstract: A light emitting diode (LED) flicker mitigation system disposed on a vehicle captures multiple images of an exterior scene to determine whether a light that appears to be off is actually off, or whether the state of the light is actually on but erroneously shown in the system image captures as off due to temporal aliasing. The LED flicker mitigation system may obtain information from external infrastructure and contact other vehicles proximate to the captured scene to determine the true state of the LED light source by identifying homography using the vehicle image captures, infrastructure information, and vehicle sensors. The images may be shared amongst the vehicles to correctly determine the LED status and correct any erroneous LED state information.

Abstract: A bracket for a display assembly includes a body that has a first edge and a second edge that define a first surface and a second surface of the body. An elongated retention feature is coupled to the first edge of the body and defines an elongated slot proximate to the first surface of the body. A plurality of retention clips are coupled to the second edge of the body. Each of the plurality of retention clips define a slot proximate to the first surface of the body. At least one housing is coupled to the second surface of the body and defines locking apertures. At least one cap is selectively coupled to the at least one housing. The at least one cap defines locking features selectively disposed within the locking apertures that are defined by the at least one housing.

Abstract: A bracket for a vehicle includes a first surface that defines support ribs and a second surface. A cantilevered end defines an attachment aperture. A retention feature is coupled to an upper edge of the cantilevered end and defines a retention notch. A central portion defines an arcuate notch and a fastening aperture. An attachment end includes a coupling feature that extends outwardly from the first surface.

Abstract: A computer, including a processor and a memory, the memory including instructions to be executed by the processor to train a neural network included in a memory augmented neural network based on one or more images and corresponding ground truth in a training dataset by transforming the one or more images to generate a plurality of one-hundred or more variations of the one or more images including variations in the ground truth and process the variations of the one or more images and store feature points corresponding to each variation of the one or more images in memory associated with the memory augmented neural network. The instructions can include further instructions to process an image acquired by a vehicle sensor with the memory augmented neural network, including comparing a feature variance set for the image acquired by the vehicle sensor to the stored processing parameters for each variation of the one or more images, to obtain an output result.

Abstract: Various medical devices are described herein. More particularly, various probes used for performing lithotripsy and methods of performing lithotripsy are described. In an example, a probe comprises an elongate member comprising a proximal end, a distal end, a proximal portion, an intermediate portion, and a distal portion. The proximal portion has an outer diameter that is greater than the outer diameter of the distal portion.

Abstract: A vehicle subscribed to an authentication system includes a wireless transceiver; and a controller, configured to responsive to receiving a wireless signal from a device identified as a key fob via the wireless transceiver, obtain history data reflecting time and location of the key fob associated with the vehicle detected via one or more entities subscribed to the authentication system, calculate a sanity value using the history data, such that a distant detection location from the vehicle location at a time before present time results in a lesser sanity value and a nearby detection location from the vehicle location at substantially the same time before the present time results in a greater sanity value, calculate a sanity threshold using at least one of the present time and the vehicle location, and responsive to the sanity value being greater than the sanity threshold, unlock a door of the vehicle.

Abstract: An interactive streaming media and application service provider system can securely stream high resolution, multiple formats of video and data. Different data sets can be included in a single stream. A rights management system controls matrix manipulation and other aspects of user control of the data, including one or more of rendering in various different 2D, 3D, or other media formats, reconstruction and modeling, zooming, frame grab, print frame, parental controls, picture in picture, preventing unauthorized copying, adapting to different data transmission formats, adapting to different resolutions and screen sizes, and actively control functionality contained in embedded data, encryption/decryption. Control can be exerted by an external entity through a user-side virtual machine. Control codes can optionally be embedded in the media, embedded in the user's device, and/or sent separately to the device.

Abstract: A trailer detection system for a vehicle includes a trailer sensor, an imaging system, and a controller. The controller implements a trailer angle indication process including receiving and processing image data to identify a rotation point of a trailer coupled with the vehicle about a fifth-wheel hitch, left and right lateral edges of the trailer, and a distance between a rear portion of a cab of the vehicle and a front face of the trailer. Trailer yaw rate data is received and processed to determine an angle of the trailer about the rotation point, and an expected position of the front face of the trailer and at least one of the left and right lateral edges of the trailer with respect to the cab of the vehicle is calculated.

Abstract: The disclosure provides systems and methods for tracking luggage. Luggage is tracked by associating the luggage with a user account during a loading action and during an unloading action. The system further includes systems and methods for retrieving lost luggage.