Patents Assigned to JIANGNAN UNIVERSITY
  • Patent number: 11963542
    Abstract: The present disclosure discloses a casein micelle with composition and structural features simulating human milk and a preparation method thereof. The method includes the following steps: adding a citrate ion, a calcium ion, and a phosphate ion to a solution of compound casein to obtain a mixed solution; and then adjusting the pH of the mixed solution to 6.7-7.4, and achieving a constant volume with water to obtain a solution of the casein micelle simulating human milk. Wherein ?-casein, ?-casein, and ?s1-casein have a mass proportion of 65-71%, 17-23%, and 9-15% in the compound casein respectively. In the solution of the casein micelle simulating human milk, the concentrations of compound casein, citrate ion, calcium ion and phosphate ion were 0.3-0.6%, 1.5-4.2 mM, 4.5-10.8 mM, and 1.1-4.5 mM, respectively. The casein micelle simulating human milk of the present disclosure is similar to human milk casein micelle, and has low allergenicity.
    Type: Grant
    Filed: March 13, 2023
    Date of Patent: April 23, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Peng Zhou, Dasong Liu, Tingting Yang, Lina Zhang
  • Patent number: 11963970
    Abstract: The present disclosure discloses a preparation method of ginseng composition with high ginsenoside bioavailability. The composition is composed of ginseng powder of 250 meshes or more and ?-cyclodextrin, and the mass ratio of the ginseng powder to the ?-cyclodextrin is 1:0.05. Results show that when ?-cyclodextrin is used as a solid dispersant and added to the 1000-mesh ginseng powder at a mass ratio of 5%, the total dissolution amount is maximum; and furthermore, animal experiments (SD rats) show that the area under the plasma drug concentration-time curve (AUC0-48 h) after 48 h of ginseng powder ingestion is maximum, indicating that in-vivo bioavailability of the ginseng powder is the highest. The method of this application can effectively inhibit the aggregation of the ultra-finely pulverized 1000-mesh ginseng powder by adding the ?-cyclodextrin, thus significantly improving the total dissolution amount of ginsenoside.
    Type: Grant
    Filed: September 13, 2023
    Date of Patent: April 23, 2024
    Assignees: JIANGNAN UNIVERSITY, STANDARD FOODS (CHINA) CO., LTD, LE BONTA WELLNESS CO., LTD
    Inventors: Peng Zhou, Changshu Liu, Tao Yang, Chang Liu, Yaowei Liu, Zikuan Zhao, Jianguo Liu, Kexin Li
  • Patent number: 11964249
    Abstract: The disclosure discloses a milk protein concentrate-based microencapsulation wall material and microcapsules, and belongs to the technical field of microcapsule preparation. In the disclosure, liquid or solid microcapsules are prepared by performing cation exchange treatment on milk protein concentrates, and then using the treated milk protein concentrates as a wall material. The prepared microcapsules have good physical and chemical stability during storage, and are suitable for protecting active functional factors and to be applied in the fields of food, medicine, health care products, cosmetics, daily chemicals and the like.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: April 23, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Peng Zhou, Jinhua Hu, Fengchen Zhuang, Xiang Li, Yuejie Jin, Chaoyue Zhang, Minjun Cheng, Yongxue Liang
  • Patent number: 11965141
    Abstract: Disclosed is food-grade lubricating grease and a method for preparing the same, belonging to the technical field of lubricating grease. The food-grade lubricating grease is prepared from the following components in percentage by mass: 75% to 85% of food-grade white oil, 6% to 16% of stearic acid, 2.0% to 3.0% of benzoic acid, 4.7% to 8.7% of aluminum isopropoxide, 1.0% to 1.5% of water and 1.0% to 7.0% of nano-PTFE, and has good extreme-pressure, abrasion-resistant and friction-reduction properties, a last non-seizure load (PB) reaching 411.6 N, a sintering load (PD) reaching 1,960 N, and a friction coefficient reduced by 18.5%. The lubricating grease can be used for a food production industry and in household food appliances, the service life of a device and the service life of the food-grade lubricating grease are effectively prolonged, and meanwhile, food security is guaranteed to a certain degree.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: April 23, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Shanhua Qian, Longfei Gong, Wei Wang, Zifeng Ni, Juan Tang
  • Patent number: 11965196
    Abstract: The disclosure relates to an enzymatic preparation method of inclusion complexes of tributyrin, and belongs to the technical field of oil microencapsulation. The disclosure combines enzymatic synthesis of cyclodextrin and inclusion of tributyrin with cyclodextrin, including enzymatic preparation of cyclodextrin with a CGT enzyme. Tributyrin is added in the preparation process; after reaction, Tween is added, and homogenization and spray drying are carried out. The effect of the finally obtained tributyrin powder is much better than that of single inclusion of tributyrin with cyclodextrin. The disclosure is simple in process, low in cost and convenient in operation; reaction processes are free of toxicity and pollution; there are no toxic reagent residues; the inclusion effect is obvious, and better utilization of a nutritional additive tributyrin in actual production is facilitated.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: April 23, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Caiming Li, Zhaofeng Li, Shuangdi Chen, Zhengbiao Gu, Yan Feng, Zexi Li, Li Cheng, Yan Hong
  • Patent number: 11959113
    Abstract: The disclosure discloses a production process and application of fermented tapioca starch for baking, and belongs to the fields of starch deep processing and food processing and production. The disclosure develops a production method of the fermented tapioca starch for baking. The method includes simple steps and greatly shortens a process cycle. By using tapioca starch as a main raw material and adding a specific amount of carbon source and a specific strain, under the action of fermentation and illumination in cooperation, the structure of the starch is improved. By adding the fermented tapioca starch, the effects of increasing the size of gluten-free Mochi bread, increasing pores of the bread and improving the texture and taste of the bread are realized.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: April 16, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Yan Hong, Qiaoting Qi, Zhengbiao Gu, Li Cheng, Zhaofeng Li, Caiming Li
  • Patent number: 11959901
    Abstract: Provided are method and system for rapidly predicting foaming tendency of edible frying oil, including: heating the oil; immersing a polar component content detection probe into the oil to measure an initial polar component content of the oil; at a frying state, removing the detection probe from the oil, placing frying food into the oil and frying the same taking out the frying food from the oil after frying, and measuring the largest frying oil foam height and recording the same as an initial foam height; at an air introduction state, immersing the detection probe and introducing air into the oil, and continuing to introduce air and heat thereinto until the polar component content in the oil is 10%; repeating the frying state; and fitting measurements and parameters into a formula.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: April 16, 2024
    Assignee: Jiangnan University
    Inventors: Gangcheng Wu, Hui Zhang, Xu Li, Xingguo Wang, Qingzhe Jin, Linglu Meng, Linya Shao, Zhengmei Zhao, Yanting Lu
  • Patent number: 11951450
    Abstract: A processing system and processing method for blocked microreactor. The processing system comprises an gas intake device, a flushing device, a microreactor to be processed and a plasma processing device. One end of the microreactor to be processed is connected with the gas intake device and the flushing device through a pipeline; the other end of the microreactor to be processed is connected with a waste liquid bottle through the pipeline; and the microreactor to be processed is arranged between electrodes of the plasma processing device. The present invention uses the effective reactivity of plasma and active free radicals in an excitation atmosphere to crack micro blockage in a micro channel in a short time. The method of the present invention has high flexibility and strong controllability, and can select plasma electrodes according to blocked regions to crack the blockage in a specific region.
    Type: Grant
    Filed: October 31, 2022
    Date of Patent: April 9, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Liangliang Lin, Ziyi Zhang, Lichen Rui
  • Patent number: 11946197
    Abstract: The present disclosure relates to a method for modifying polyester by a swelling agent combined with cutinase, belonging to the technical field of textile processing. According to the method, a phenol solution or an o-vanillin solution is used as the swelling agent to perform swelling treatment on the polyester, and combined with a Humicola insolens cutinase solution to perform hydrophilic modification on the polyester, which not only significantly improves the release amount of hydrolysates, but also reduces the fabric mass loss compared with the traditional chemical modification method.
    Type: Grant
    Filed: July 27, 2023
    Date of Patent: April 2, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jiajia Fu, Jundan Feng, Artur Cavaco-paulo, Rong Li, Yuzheng Lu, Xinming Zheng, Ruijuan Han, Chaoran Meng
  • Patent number: 11946088
    Abstract: The disclosure discloses a method for processing oil crops with rhodotorula, and belongs to the technical field of fermentation. The method includes the step of inoculating the rhodotorula (such as Rhodotorula mucilaginosa, Sporidiobolus salmonicolor and Rhodotorula glutinis) that can produce carotenoid into a fermentation medium that contains oil-rich oil crops for solid state fermentation to obtain oil and oil crop meal rich in carotenoid. The carotenoid as a fermentative metabolite of the rhodotorula has bioactivities of resisting oxidation, preventing vascular sclerosis, enhancing immunity and preventing cancers. Contents of carotenoid in the oil and oil crop meal acquired by the method can be up to 9.071 ?g/g and 8.062 ?g/g correspondingly.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: April 2, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Yuanfa Liu, Zhongyang Ding, Yunzhi Jiang, Liting Zhao, Mengmeng Xu, Qi Zhang, Zhenghua Gu, Guiyang Shi
  • Patent number: 11946196
    Abstract: The present disclosure discloses an atmospheric-pressure plasma equipment for fabric functional finishing and its application, and belongs to the field of textile printing and dyeing engineering. The atmospheric-pressure plasma equipment, including a discharging system, a grafting instrument and a cloth guider, can conduct continuous plasma treatment on fabrics under an atmospheric pressure, including plasma etching and plasma grafting, which breaks through the disadvantage of batch processing of vacuum plasma equipment. The equipment and method of the present disclosure realize functional finishing of the fabrics in the absence of water, and this finishing process is cost efficient, environmentally friendly, uniform, shorter treatment time and higher reactivity, and applicable to many materials and can keep the bulk properties of the treated substances.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: April 2, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Chang-E Zhou, Hongwei Wang, Wenkai Shen, Lei Fan, Xin Ju, Guozheng Zhang, Tongxin Yang, Wanning Wang, Chang Sun
  • Patent number: 11938465
    Abstract: The invention discloses a coordination type zirconium phosphotungstate catalyst and its application in catalytic hydrogenation of furfural, belonging to the field of heterogeneous catalysis. The zirconium phosphotungstate catalyst prepared by the invention not only has good catalytic effect on the conversion of furfural to furfuryl alcohol, but also has mild reaction conditions. The yield of solid line furfuryl alcohol can be 98% if it can be reacted for 1 h at 120 ° C., and the amount of catalyst is less, which greatly reduces the energy consumption in the prior art. In addition, the zirconium phosphotungstate prepared by the invention is easy to separate, has good stability for catalyzing the hydrogenation of furfural to furfuryl alcohol, and is a new, efficient and green catalyst.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: March 26, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Liping Zhang, Haijun Wang, Guangzhi Xu, Chen Liu
  • Patent number: 11938629
    Abstract: A micro-robot magnetic drive device and a control method based on double closed loop three-dimensional path tracking are disclosed. The method includes: inputting a desired tracking path, obtaining current pose information of a magnetic micro-robot through a camera, and then calculating a position of a center of mass, an actual axial direction, coordinates of a desired position point with the shortest distance from the center of mass on a desired tracking path, and a tangent direction of this point; calculating a horizontal distance, a vertical distance, a direction angle error, and a pitch angle error of the two points according to the actual axial direction, the tangent direction, and disturbance compensation; and obtaining a required rotating magnetic field according to a designed position closed loop controller.
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: March 26, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Qigao Fan, Wei Chen, Linbai Xie, Yixin Zhu, Guofeng Yang, Yueyang Li, Kaitao Bi, Wentao Huang, Haichi Luo, Zhengqing Zhao
  • Patent number: 11925708
    Abstract: The invention provides a making method of modified polyvinyl alcohol embolic microspheres. First, polyvinyl alcohol dimethyl sulfoxide solution is added to acryloyl chloride dichloromethane solution for reaction, then taurine solution is added to the above solution for further reaction, so that functional groups are introduced into the side chains of polyvinyl alcohol, then blank microspheres are prepared by suspension crosslinking method, and finally, drug-loaded modified polyvinyl alcohol embolic microspheres are prepared. The invention aims at improving the drug loading rate and drug loading speed of the microspheres. Through modification, the crystallinity of polyvinyl alcohol is weakened, the swelling in water is accelerated, and the application effect of the microspheres is improved.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: March 12, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Liping Zhang, Yi Zhu, Wenlong Wang, Caihua Ni
  • Patent number: 11911353
    Abstract: The disclosure discloses a fatty acid synthase inhibitor and application thereof and belongs to the technical field of medical biology. The fatty acid synthase inhibitor of the disclosure can significantly inhibit the activity of fatty acid synthase without affecting normal expression, and adjust the ratio of fatty acids in cells. The fatty acid synthase inhibitor of the disclosure has a good tumor proliferation inhibitory effect, can arrest the growth cycle of tumor cells in the interphase, prevent tumor cell division, inhibit tumor cell proliferation, promote tumor cell apoptosis and exert a tumor treatment effect, can be used to treat tumors and metabolism related diseases, and has an important clinical application prospect.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: February 27, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Yongquan Chen, Hongyan Qu, Chunlei Tang, Guosheng Wu, Guozhen Cui, Ninghan Feng, Xiaoying Wang, Kai Shan, Shenglong Zhu, Lengyun Wei
  • Publication number: 20240060076
    Abstract: The disclosure relates to a thermal switch system and application thereof in improving yield of amino acid, and particularly relates to a method for improving the yield of amino acid by regulating intracellular metabolic flux distribution using the thermal switch system, which belongs to the technical fields of genetic engineering and microbial fermentation. The system rebalances metabolic flux between pyruvate and oxaloacetate by controlling heterologous expression of pyruvate carboxylase and in combination with chemical properties that oxaloacetate is temperature-sensitive and easy to decarboxylate, and dynamically regulates a central metabolic pathway to ensure the supply of reducing cofactors, so as to promote the production of L-threonine. Temperature-controlled threonine-producing strains TWF106/pFT24rp and TWF113/pFT24rpa1 obtained in the disclosure have threonine molar conversion rates of 111.78% and 124.03% respectively.
    Type: Application
    Filed: May 17, 2022
    Publication date: February 22, 2024
    Applicant: Jiangnan University
    Inventors: Xiaoyuan WANG, Yu FANG, Jianli WANG, Shuyan ZHANG, Xiaoqing HU
  • Patent number: 11910536
    Abstract: In a direct-ink-writing (DIW) method for printing a strain gauge array circuit, several insulating strips are printed on the upper layer of the first circuit layer after the first circuit layer has been printed and cured, and the second circuit layer is then printed at the insulating strips. The functional layer of a strain gauge is printed and covered thereon without contacting the insulating strips; the head and tail electrodes of the functional layer are respectively connected to two layers of circuit layers; and finally, a layer of insulating material is printed for encapsulation. DIW is used to complete the whole printing. A new insulating method is used in a cross part of two silver lines of a row-column compound circuit. The local glue dispensing is changed to printing the insulating strips in routing regions, and ensures the strain transmission efficiency from the strain gauge substrate to the functional layer.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: February 20, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Peishi Yu, Junhua Zhao, Lixin Qi, Zhiyang Guo, Yu Liu
  • Patent number: 11903401
    Abstract: A method for increasing the yield of Amadori rearrangement products (ARP) based on a mechanism in which addition of tea polyphenols to deoxyosones inhibits degradation of the ARP. The method includes the following steps: dissolving and mixing amino acid, sugar and tea polyphenol in water, and adjusting a pH value; placing the obtained mixed solution in a reaction flask, and heating the mixed solution at a constant temperature in a water bath to obtain a reaction solution; and performing vacuum decompression dehydration reaction at a constant temperature; after the reaction is completed, using an ice bath to terminate the reaction to obtain a solid reactant, and redissolving the solid reactant in water to obtain an ARP solution. This method promotes the formation of ARP and inhibits degradation of ARP, so that ARP is accumulated and enriched in a large amount (80% and above yield).
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: February 20, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Xiaoming Zhang, Junhe Yu, Heping Cui, Huan Zhan, Yun Zhai, Jingyang Yu, Shuqin Xia
  • Patent number: 11891490
    Abstract: Disclosed are a protective starch-based film and its preparation method and application, belonging to the field of food packaging. According to the method for preparing the protective starch-based film, surfaces of zinc oxide nanoparticles are enabled to adsorb tannic acid and iron ions under the action of metal coordination by controlling the pH to obtain metallic polyphenol network coated zinc oxide nanoparticles, dispersion of the obtained nanoparticles is added to a starch gelatinization solution, and a melanin-like precursor is simultaneously added to form mixed liquid; and by controlling the pH of the mixed solution, ?-? stacking, self-polymerization and metal coordination are induced, so that a stable protective starch-based film with a nano-reinforced interpenetrating network structure is formed.
    Type: Grant
    Filed: August 14, 2023
    Date of Patent: February 6, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Long Chen, Hao Xu, Zhengyu Jin, Ming Miao, Yaoqi Tian, Xinwen Peng, Yidong Zou, Guanxiong Chen
  • Patent number: 11879071
    Abstract: The present disclosure discloses a low-viscosity thermosetting starch adhesive for particleboards, and a preparation method therefore, belonging to the technical field of adhesive preparation. The adhesive of the present invention selects N-hydroxyethyl acrylamide or acetoxyethyl methacrylate as the crosslinking monomer, which has a low degree of crosslinking in the process of adhesive preparation to avoid the problem of increasing viscosity, but can cross-link quickly during the hot pressing process, forming a network structure, and improving the water resistance of the adhesive; and furthermore, itaconic acid is added to promote the self-crosslinking reaction of the crosslinking monomer in the hot-pressing process, thus further improving the water resistance.
    Type: Grant
    Filed: June 13, 2023
    Date of Patent: January 23, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Li Cheng, Junnan Jin, Zhengbiao Gu, Zhaofeng Li, Yan Hong, Caiming Li, Xiaofeng Ban